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Anyone treated with enzalutamide +cabazitaxel?
Hi, I have stage4b with extensive bone mets. I've had sequentially ADT+abiraterone; docetaxel+carboplatin; Pluvicto. PSA never got below 3. Latest CT bone scan shows progression in a few areas. RO will zap the progressing areas locally. MO suggested cabazitaxel (1st choice) or enzalutamide (discouraged
Hi, I have stage4b with extensive bone mets. I've had sequentially ADT+abiraterone; docetaxel+carboplatin; Pluvicto. PSA never got below 3. Latest CT bone scan shows progression in a few areas. RO will zap the progressing areas locally. MO suggested cabazitaxel (1st choice) or enzalutamide (discouraged
BeLikeWater
in
Advanced Prostate Cancer
5 days ago
PMR or PsA or both
I'm on prednisone since last April and have managed to get down from 35 to 10 mg with a few minor flares. My Rheumatologist thinks it could be PMR or PsA or both. Can't get a definite answer. It started overnight after a fall I had. Now I wake up really achy all over and after about an hour feel fine
I'm on prednisone since last April and have managed to get down from 35 to 10 mg with a few minor flares. My Rheumatologist thinks it could be PMR or PsA or both. Can't get a definite answer. It started overnight after a fall I had. Now I wake up really achy all over and after about an hour feel fine
Seal49
in
PMRGCAuk
5 days ago
what now failed R223
‘what now’ failed R223 My husband this week because of low Hb 83 had a blood transfusion + iron infusion. He has suffered ‘Proctitis’ rectal bleeding since having radiotherapy 2019 and although complaining to Oncologist, GP, Gastroenterologist had endoscopy (found Barrett’s disease and has difficulty
‘what now’ failed R223 My husband this week because of low Hb 83 had a blood transfusion + iron infusion. He has suffered ‘Proctitis’ rectal bleeding since having radiotherapy 2019 and although complaining to Oncologist, GP, Gastroenterologist had endoscopy (found Barrett’s disease and has difficulty
Janhpr
in
Advanced Prostate Cancer
5 days ago
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Minor psa increase again
Just over 12 months since adt finished. All clear at <0.01 2 months ago when it started to rise to 0.03 then 4 weeks later 0.05 now 0.07. Have Dr's app in 3 weeks which will probably be a referral back to oncologist. Do we need to wait until 2.0 then a PET scan or can I be proactive now? My adt was
Just over 12 months since adt finished. All clear at <0.01 2 months ago when it started to rise to 0.03 then 4 weeks later 0.05 now 0.07. Have Dr's app in 3 weeks which will probably be a referral back to oncologist. Do we need to wait until 2.0 then a PET scan or can I be proactive now? My adt was
Runner1957
in
Prostate Cancer Network
6 days ago
PSA Rising and Falling during Chemo
I have been receiving chemotherapy since November 2023. Started with Docetaxel until it failed after 7 cycles. Switched to Cabazitaxel and currently on the 5th cycle. Since starting the Cabazitaxil my PSA has been raising and lowering. I am currently having some scans done to confirm if there is progression
I have been receiving chemotherapy since November 2023. Started with Docetaxel until it failed after 7 cycles. Switched to Cabazitaxel and currently on the 5th cycle. Since starting the Cabazitaxil my PSA has been raising and lowering. I am currently having some scans done to confirm if there is progression
Islandboy2021
in
Advanced Prostate Cancer
7 days ago
PSA level from 4 (Dec 2023) to 22 (present)
Hello, I am posting on behalf of my father. He tested a level of 4 PSA back in Dec 2023; the doctor did not say much except try to keep your stress level down, etc. He felt things were feeling quite abnormal so went back to doctor April this year and tested a level of 8 PSA so he was finally referred
Hello, I am posting on behalf of my father. He tested a level of 4 PSA back in Dec 2023; the doctor did not say much except try to keep your stress level down, etc. He felt things were feeling quite abnormal so went back to doctor April this year and tested a level of 8 PSA so he was finally referred
Dodododo
in
Prostate Cancer Network
8 days ago
Anyone out there start Pluvicto at 85 or older?…Oncologist wants me to try but I’m Hesitant due to side effects possible…
I’m 10 years into the battle …Last 4 1/2 Metastatic….my oncologist wants me to try Pluvicto….Im feeling pretty good right now and can do most things…..I’ve had chemo and 78 proton beam treatments and also 7 months of BAT…He says I’ll tolerate it good and if not we can just quit….I know you just can’t
I’m 10 years into the battle …Last 4 1/2 Metastatic….my oncologist wants me to try Pluvicto….Im feeling pretty good right now and can do most things…..I’ve had chemo and 78 proton beam treatments and also 7 months of BAT…He says I’ll tolerate it good and if not we can just quit….I know you just can’t
Roxysdad
in
Advanced Prostate Cancer
8 days ago
Phase 1b: FOR46, a novel antibody-drug conjugate targeting a tumor-specific epitope of CD46, in combination with Enza in patients with mCRPC
"Preliminary anti-tumor activity was observed with PSA declines in 13/16 (81.3%) of evaluable pts, and a disease control rate (stable disease ≥ 6 months) of 41.2%" But side effects could be very hard on heavily pretreated patients https://ascopubs.org/doi/10.1200/JCO.2024.42.16_suppl.5066
"Preliminary anti-tumor activity was observed with PSA declines in 13/16 (81.3%) of evaluable pts, and a disease control rate (stable disease ≥ 6 months) of 41.2%" But side effects could be very hard on heavily pretreated patients https://ascopubs.org/doi/10.1200/JCO.2024.42.16_suppl.5066
Maxone73
in
Advanced Prostate Cancer
9 days ago
Castrate Resistant
I know that patients who were started at beginning with combo of, say, Lupron plus abiraterone acetate are declared castrate resistant when PSA rises in certain ways and/or progression is shown on scans. However, for someone like me, who's been on Lupron only since diagnosis, am I not castrate resistant
I know that patients who were started at beginning with combo of, say, Lupron plus abiraterone acetate are declared castrate resistant when PSA rises in certain ways and/or progression is shown on scans. However, for someone like me, who's been on Lupron only since diagnosis, am I not castrate resistant
dhccpa
in
Advanced Prostate Cancer
9 days ago
TRUST IN HEALTHCARE : free registration at https://malecare.org/trust-in-healthcare
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Darryl
Partner
in
Prostate Cancer Network
9 days ago
TRUST IN HEALTHCARE : free virtual conference for patients, friends and those you care about
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Darryl
Partner
in
LGBT Cancer Community
9 days ago
DO YOU TRUST YOUR DOCTOR : Free registration at https://malecare.org/trust-in-healthcare
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Darryl
Partner
in
Advanced Prostate Cancer
9 days ago
DO YOU TRUST YOUR DOCTOR? Free registration at malecare.org/trust-in-healthcare
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Darryl
Partner
in
Active Surveillance - Prostate Cancer
9 days ago
Phase 2 trial: Evaluation of Treatment Interruption After Response in mHSPC
"Patients are allowed to enrolle if they have a stable or falling prostate-specific antigen (PSA) level below 0.2 ng/mL and a castrate testosterone level under 50 ng/dL at baseline after having a PSA level of at least 5 ng/mL and a testosterone level of at least 150 ng/dL prior to the start of ADT. "
"Patients are allowed to enrolle if they have a stable or falling prostate-specific antigen (PSA) level below 0.2 ng/mL and a castrate testosterone level under 50 ng/dL at baseline after having a PSA level of at least 5 ng/mL and a testosterone level of at least 150 ng/dL prior to the start of ADT. "
Maxone73
in
Advanced Prostate Cancer
9 days ago
Should I do chemotherapy?
New here. I am 81 and was diagnosed last month with PCa metastatic to a few bones. Gleason 9. PSA 21 at diagnosis. Have been put on orgovyx and xtandi. Chemo was not mentioned. Reading some posts here I wonder if chemo would be an important option for me ? I will turn 82 In a few
New here. I am 81 and was diagnosed last month with PCa metastatic to a few bones. Gleason 9. PSA 21 at diagnosis. Have been put on orgovyx and xtandi. Chemo was not mentioned. Reading some posts here I wonder if chemo would be an important option for me ? I will turn 82 In a few
Simpson80
in
Advanced Prostate Cancer
9 days ago
After Orgovyx
Age 76, diagnosed with advanced prostate cancer in December 2021. PSA was 8.6, but had zero symptoms. Started Orgovyx in February 2022 and received 25 treatments of external radiation therapy starting in March 2022. Treated in April 2022 with brachytherapy. Current PSA is negligible, but urologist
Age 76, diagnosed with advanced prostate cancer in December 2021. PSA was 8.6, but had zero symptoms. Started Orgovyx in February 2022 and received 25 treatments of external radiation therapy starting in March 2022. Treated in April 2022 with brachytherapy. Current PSA is negligible, but urologist
BubbaC
in
Prostate Cancer Network
10 days ago
When to Commence ADT and/or Androgen Blocking Therapy?
Greetings All - New to this forum but have followed the Healing Well PC forum since beginning treatment in 2018 and later began to follow Prostate Cancer News, Reviews and Views which referenced this forum. The details are provided below but my question is: At what ultra-sensitive (LabCorp) PSA level
Greetings All - New to this forum but have followed the Healing Well PC forum since beginning treatment in 2018 and later began to follow Prostate Cancer News, Reviews and Views which referenced this forum. The details are provided below but my question is: At what ultra-sensitive (LabCorp) PSA level
Biochem
in
Advanced Prostate Cancer
10 days ago
Ckd with one kidney
I am on 10mg per day Amlodepine. My blood pressure readings are 123/65/63. With just one kidney, eGFR is 46 PSA is 0. 7ug/l and Creatinine is127umol/l. On food supplements for my kidney and liver from Japan. Very stable virtually no pain from area of kidney.
I am on 10mg per day Amlodepine. My blood pressure readings are 123/65/63. With just one kidney, eGFR is 46 PSA is 0. 7ug/l and Creatinine is127umol/l. On food supplements for my kidney and liver from Japan. Very stable virtually no pain from area of kidney.
Amsaved
in
Kidney Disease
10 days ago
Predicting Response to Bipolar Androgen Therapy - A Blood Based Biomarker Approach
Recently there has been a number of posts and subsequent responses from members of Fight Prostate Cancer on Bipolar Androgen Therapy. This very recent UroToday video (see link) in which Professor Samuel Denmeade is interviewed by Alicia Morgans might be of interest to some on this forum. In the
Recently there has been a number of posts and subsequent responses from members of Fight Prostate Cancer on Bipolar Androgen Therapy. This very recent UroToday video (see link) in which Professor Samuel Denmeade is interviewed by Alicia Morgans might be of interest to some on this forum. In the
marnieg46
in
Fight Prostate Cancer
10 days ago
AI to predict clinical trials outcome
"Dr. Sabbagh explains that traditional endpoints like overall survival often require long follow-ups, delaying access to potentially life-saving treatments. His research leverages baseline clinical characteristics and PSA changes over four months to accelerate predictions of trial outcomes. " It would
"Dr. Sabbagh explains that traditional endpoints like overall survival often require long follow-ups, delaying access to potentially life-saving treatments. His research leverages baseline clinical characteristics and PSA changes over four months to accelerate predictions of trial outcomes. " It would
Maxone73
in
Advanced Prostate Cancer
10 days ago
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