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Neutropenia
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What to ask immunologist
These symptoms were gradually joined by many others, including joint and muscle pains and blood tests showed low C3 and C4, intermittent
neutropenia
, and low iron.
These symptoms were gradually joined by many others, including joint and muscle pains and blood tests showed low C3 and C4, intermittent
neutropenia
, and low iron.
Ophelia1
in
LUPUS UK
3 years ago
AbbVie Pharm--positive phase 3 for CLL!
The most frequently occurring serious adverse reactions in patients receiving venetoclax in combination with obinutuzumab were pneumonia, sepsis, febrile
neutropenia
, and TLS.
The most frequently occurring serious adverse reactions in patients receiving venetoclax in combination with obinutuzumab were pneumonia, sepsis, febrile
neutropenia
, and TLS.
Vlaminck
in
CLL Support
3 years ago
Neutrophils update.
After my oncologist appt I looked into all of this, and discovered this paper explaining the neutrophil issue. https://www.cancer.net/coping-with-cancer/physical-emotional-and-social-effects-cancer/managing-physical-side-effects/
neutropenia
I realised I had had pretty well all of the symptoms mentioned
After my oncologist appt I looked into all of this, and discovered this paper explaining the neutrophil issue. https://www.cancer.net/coping-with-cancer/physical-emotional-and-social-effects-cancer/managing-physical-side-effects/
neutropenia
I realised I had had pretty well all of the symptoms mentioned
Beryl71
in
SHARE Metastatic Breast Cancer
3 years ago
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Oesophagus pain, What Private Tests ?
I also have mild
Neutropenia
at 1.4, and other low bloods, quite possibly from radiotherapy in my 20s,and whatever is going on at the moment. I'm a divorced man with no one to talk this over with i guess i'm just looking for people whom have had similar experiences to chat with.
I also have mild
Neutropenia
at 1.4, and other low bloods, quite possibly from radiotherapy in my 20s,and whatever is going on at the moment. I'm a divorced man with no one to talk this over with i guess i'm just looking for people whom have had similar experiences to chat with.
jezburg
in
Oesophageal & Gastric Cancer
3 years ago
Is this an autoimmune flare up....or some sort of low Ferritin hinterland?
I always have a borderline/low white cell count and have previously been monitored for
Neutropenia
but never really got to the bottom of the cause. I think this could be autoimmune?? On this occasion lower than usual.
I always have a borderline/low white cell count and have previously been monitored for
Neutropenia
but never really got to the bottom of the cause. I think this could be autoimmune?? On this occasion lower than usual.
MacG
in
Thyroid UK
3 years ago
Zanubrutinib looks promising on all fronts in first interim analysis of ALPINE Trial - Ibrutinib v Zanubrutinib in R/R CLL - report from EHA
Rate of
neutropenia
was higher with zanubrutinib (28.4% vs 21.7%), while grade ≥3 infections were lower with zanubrutinib (12.7% vs 17.9%).
Rate of
neutropenia
was higher with zanubrutinib (28.4% vs 21.7%), while grade ≥3 infections were lower with zanubrutinib (12.7% vs 17.9%).
Jm954
Administrator
in
CLL Support
3 years ago
Anaemia and neutropenia with Peg?
Does anyone have any experience of having severe anaemia, and / or
neutropenia
, while taking Peg? I’m currently on 90mcg Pwg weekly for post-ET MF, JAK2+. I’m 41yo and eat a pescatarian diet including all the leafy greens.
Does anyone have any experience of having severe anaemia, and / or
neutropenia
, while taking Peg? I’m currently on 90mcg Pwg weekly for post-ET MF, JAK2+. I’m 41yo and eat a pescatarian diet including all the leafy greens.
LucyGeering
in
MPN Voice
3 years ago
Long-Term Data Showcase the Clinical Utility of Fixed-Duration Venetoclax/Obinutuzumab in Treatment-Naïve CLL
After treatment, no toxicity was observed, so we don’t see any long-term hematologic toxicities or late-onset
neutropenia
. Those are [toxicities] that we might have seen in the era of more intensive chemoimmunotherapies.
After treatment, no toxicity was observed, so we don’t see any long-term hematologic toxicities or late-onset
neutropenia
. Those are [toxicities] that we might have seen in the era of more intensive chemoimmunotherapies.
lankisterguy
Volunteer
in
CLL Support
3 years ago
New therapy for Small Cell Lung Cancer patients to lower chance of getting neutropenia: FDA Approval of COSELA (trilaciclib)
The FDA based their approval off of three different clinical trials which showed that patients receiving Cosela along with their chemotherapy had a lower chance of getting
neutropenia
(low white blood cell count) and those that did experience
neutropenia
had it for a shorter period of time.
The FDA based their approval off of three different clinical trials which showed that patients receiving Cosela along with their chemotherapy had a lower chance of getting
neutropenia
(low white blood cell count) and those that did experience
neutropenia
had it for a shorter period of time.
Miranda_GO2
Partner
in
Lung Cancer Support
3 years ago
Phase 2 study of MRD driven time limited therapy with Zanubrutinib, Obintuzumab and Venetoclax (BOV) in untreated patients.
The most common treatment emergent AEs were
neutropenia
(49%), infusion related reaction (41%), bruising (41%), diarrhea (39%) and thrombocytopenia (36%). Grade ≥3 AEs occurring in ≥5% pts were
neutropenia
(15%), thrombocytopenia (5%) and pneumonia (5%).
The most common treatment emergent AEs were
neutropenia
(49%), infusion related reaction (41%), bruising (41%), diarrhea (39%) and thrombocytopenia (36%). Grade ≥3 AEs occurring in ≥5% pts were
neutropenia
(15%), thrombocytopenia (5%) and pneumonia (5%).
Jm954
Administrator
in
CLL Support
3 years ago
Cabazitaxel vs Abiraterone or Enzalutamide in Poor-Prognosis Metastatic Castration-Resistant Prostate Cancer
The most common first-line treatment-related grade ≥3 adverse events were
neutropenia
(cabazitaxel 32% vs ARPI 0%), diarrhea (9% vs 0%), infection (9% vs 0%) and fatigue (7% vs 5%).
The most common first-line treatment-related grade ≥3 adverse events were
neutropenia
(cabazitaxel 32% vs ARPI 0%), diarrhea (9% vs 0%), infection (9% vs 0%) and fatigue (7% vs 5%).
Balsam01
in
Advanced Prostate Cancer
3 years ago
Newbie question on prednisolone short course
I have intermittent
neutropenia
and this too is a concern especially as I want to have the Covid vaccine asap. Is it likely that I will be able to improve enough to come off prenisolone after 4 weeks ?
I have intermittent
neutropenia
and this too is a concern especially as I want to have the Covid vaccine asap. Is it likely that I will be able to improve enough to come off prenisolone after 4 weeks ?
Humphreydonk
in
PMRGCAuk
3 years ago
Quick Question to anyone previously shielding, over 70 and in Scotland
My Dad has
neutropenia
and may need a bone marrow transplant, my aunt has just finished chemo for Non Hodgkins and neither has received an invite but at least a dozen friends all in their 70s with no health conditions have all received letters and are booked in.
My Dad has
neutropenia
and may need a bone marrow transplant, my aunt has just finished chemo for Non Hodgkins and neither has received an invite but at least a dozen friends all in their 70s with no health conditions have all received letters and are booked in.
Froggie70
in
LUPUS UK
3 years ago
Switching from Ibrutinib because of neutropenia
I am curious what medication you have been switched to because Ibrutinib was causing
neutropenia
? Did the new medication worked better ?
I am curious what medication you have been switched to because Ibrutinib was causing
neutropenia
? Did the new medication worked better ?
MikeOr
in
CLL Support
4 years ago
Strange case of CLL remission
He did cycle 1 with no issues, cycle 2 with no issues except a severe
neutropenia
where all white cells dropped to 0. The doctor advised us to stop. A month later, all his blood levels restored to levels not seen even during the first treatment.
He did cycle 1 with no issues, cycle 2 with no issues except a severe
neutropenia
where all white cells dropped to 0. The doctor advised us to stop. A month later, all his blood levels restored to levels not seen even during the first treatment.
mkawass
in
CLL Support
3 years ago
Reduced dose Acalabrutinib
Acalabrutinib keeps my CLL in check but gives me
neutropenia
. One strategy would be to cut the usual dose in half to 100 mg/day. Does anyone have experience with this dose? Is it possible that a dose that low could be effective?
Acalabrutinib keeps my CLL in check but gives me
neutropenia
. One strategy would be to cut the usual dose in half to 100 mg/day. Does anyone have experience with this dose? Is it possible that a dose that low could be effective?
john-doe
in
CLL Support
4 years ago
Autoimmune Neutropenia
Please may I ask if anyone has had experience of autoimmune
neutropenia
as I have developed this secondary to my Behcets. Basically I have developed an antibody which is destroying my own neutrophils.
Please may I ask if anyone has had experience of autoimmune
neutropenia
as I have developed this secondary to my Behcets. Basically I have developed an antibody which is destroying my own neutrophils.
NikD
in
Behçet's UK
4 years ago
Neutropenia and Imbruvica
What happens when you are getting neutropenic while taking Imbruvica ? Is your dose is reduced, or Imbruvica is stopped until numbers improve, or something else ?
What happens when you are getting neutropenic while taking Imbruvica ? Is your dose is reduced, or Imbruvica is stopped until numbers improve, or something else ?
MikeOr
in
CLL Support
4 years ago
Looking for a fifth line of CLL treatment
Most all treatments have given me
neutropenia
. My second opinion doctor said, before I started acalabrutinib, that I was running out of effective treatments (I try not to replay his words in my head) and mentioned car-t. I asked him how car-t was going.
Most all treatments have given me
neutropenia
. My second opinion doctor said, before I started acalabrutinib, that I was running out of effective treatments (I try not to replay his words in my head) and mentioned car-t. I asked him how car-t was going.
john-doe
in
CLL Support
4 years ago
BRCA, ATM, CHEK news: ASCO GU 2021: Talazoparib Demonstrates Durable Antitumor Activity in Metastatic Castration-Resistant Prostate Cancer
The most common grade 3/4 treatment-emergent adverse events were anemia (30.7%), thrombocytopenia (8.7%), and
neutropenia
(7.9%).
The most common grade 3/4 treatment-emergent adverse events were anemia (30.7%), thrombocytopenia (8.7%), and
neutropenia
(7.9%).
Balsam01
in
Advanced Prostate Cancer
3 years ago
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