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EMBARK Trial: Combination-therapy is better.
This chart compares the risk of developing metastasis from prostate cancer, after 5 years from curative treatment, between three different arms of the EMBARK study (published in 2023): (1) Lupron monotherapy; (2) Enzalutamide monotherapy; and (3) Enzalutamide + Lupron combination therapy. The cohort
This chart compares the risk of developing metastasis from prostate cancer, after 5 years from curative treatment, between three different arms of the EMBARK study (published in 2023): (1) Lupron monotherapy; (2) Enzalutamide monotherapy; and (3) Enzalutamide + Lupron combination therapy. The cohort
janebob99
in
Prostate Cancer Network
5 months ago
Hyberbaric Oxygen Therapy
I have a friend who contracted Lyme disease and recently underwent a series of hyperbaric oxygen therapy sessions. The treatment has completely transformed him and he is now his old self. I have read that this therapy helps Fibromyalgia and other autoimmune diseases and was wondering if anyone knew
I have a friend who contracted Lyme disease and recently underwent a series of hyperbaric oxygen therapy sessions. The treatment has completely transformed him and he is now his old self. I have read that this therapy helps Fibromyalgia and other autoimmune diseases and was wondering if anyone knew
Lassie2
in
PMRGCAuk
3 months ago
Nice to be here
I have just been diagnosed with severe chronic pancreatitis. I am really scared, even though I've had bad symptoms for some time. I'm on enzyme therapy and recently had to increase the dose. Would like to talk to people that have had experience with this. Thank you and I look forward to meeting you
I have just been diagnosed with severe chronic pancreatitis. I am really scared, even though I've had bad symptoms for some time. I'm on enzyme therapy and recently had to increase the dose. Would like to talk to people that have had experience with this. Thank you and I look forward to meeting you
Corinne777
in
Couch to 5K
5 months ago
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Speech production technology
Has anyone tried speech production technology, such as Stephen Hawking used, for PSP patients? Was it successful or not? Our speech therapist is asking us to consider it since we cannot understand my husband any more. Thanks
Has anyone tried speech production technology, such as Stephen Hawking used, for PSP patients? Was it successful or not? Our speech therapist is asking us to consider it since we cannot understand my husband any more. Thanks
TourEiffel
in
PSP Association
5 months ago
NDT vs T4 T3 combination therapy
Hello everyone. Please share your experience NDT vs combination therapy. Currently I am on combo but still have symptoms (I have no thyroid). I am doing better on combo than on T4 only. I want to try NDT and see if it will make me feel better. Since both of them mainly contain T4 T3 may I expect significant
Hello everyone. Please share your experience NDT vs combination therapy. Currently I am on combo but still have symptoms (I have no thyroid). I am doing better on combo than on T4 only. I want to try NDT and see if it will make me feel better. Since both of them mainly contain T4 T3 may I expect significant
Alex_N
in
Thyroid UK
6 months ago
Bayer and AskBio report data from Parkinson’s disease therapy trial
The bilateral infusions of AB-1005 were well tolerated, without any SAEs linked to the gene therapy or contrast agent. AskBio Parkinson’s and MSA Scientific chair Krystof Bankiewicz said: “These early findings are encouraging and show AB-1005 to be well tolerated in this study in patients with mild
The bilateral infusions of AB-1005 were well tolerated, without any SAEs linked to the gene therapy or contrast agent. AskBio Parkinson’s and MSA Scientific chair Krystof Bankiewicz said: “These early findings are encouraging and show AB-1005 to be well tolerated in this study in patients with mild
Farooqji
in
Cure Parkinson's
6 months ago
CRISPR 13 (what? you thought I abandoned CRISPR?): very promising proof of concept - Targeting HOXB13 in mPCa by CRISPR/Cas13d- nanoparticle
And people thought it was undruggable....they have already filed for a patent 😲 Researchers developed nanoparticles that can deliver a special type of gene therapy directly to cancer cells in the liver. This system uses a CRISPR technology, not to edit DNA, but to block the RNA of the HOXB13 protein
And people thought it was undruggable....they have already filed for a patent 😲 Researchers developed nanoparticles that can deliver a special type of gene therapy directly to cancer cells in the liver. This system uses a CRISPR technology, not to edit DNA, but to block the RNA of the HOXB13 protein
Maxone73
in
Advanced Prostate Cancer
6 months ago
constipation
years of laxative abuse leaves me with slow bowel going shortly for biofeedback as have no anal function, have to evacuate myself now I’m passing some stool with interference but so bloated and in pain, am I impacted? Starting laxido today, and a stimulant, swore never to laxative use again but scared
years of laxative abuse leaves me with slow bowel going shortly for biofeedback as have no anal function, have to evacuate myself now I’m passing some stool with interference but so bloated and in pain, am I impacted? Starting laxido today, and a stimulant, swore never to laxative use again but scared
Dudders123
in
IBS Network
6 months ago
Thyroid S in UK
Hello everyone. I am a thyroid patient from Armenia, I have no thyroid for the last 6 years. I tried T4 and T4 and T3 combination therapies, but still I feel sick with many symptoms. I would like to try NDT, can you please advise a reliable source to by Thyroid S online in UK? Thank you.
Hello everyone. I am a thyroid patient from Armenia, I have no thyroid for the last 6 years. I tried T4 and T4 and T3 combination therapies, but still I feel sick with many symptoms. I would like to try NDT, can you please advise a reliable source to by Thyroid S online in UK? Thank you.
Alex_N
in
Thyroid UK
6 months ago
Is it a waste?
How do you know when you stop making progress? If i keep going to these group therapy sessions and hanging out with my family, but have my head ducking down, into my phone or look at the ground to avoid social interactions....does it still count as a visit? i mean i'm not as bad as im describing i do
How do you know when you stop making progress? If i keep going to these group therapy sessions and hanging out with my family, but have my head ducking down, into my phone or look at the ground to avoid social interactions....does it still count as a visit? i mean i'm not as bad as im describing i do
EricJones
in
Anxiety and Depression Support
6 months ago
Music is like therapy!
I just wanted to share this with you all because music is so uplifting to me and this song makes want to get up and move! My taste in music has no genre. I just love good music. This might be retro for a lot of you, but I don't think that way.I hope you enjoy it! Let me know what you think. https://
I just wanted to share this with you all because music is so uplifting to me and this song makes want to get up and move! My taste in music has no genre. I just love good music. This might be retro for a lot of you, but I don't think that way.I hope you enjoy it! Let me know what you think. https://
HopeforMiami
in
Anxiety and Depression Support
1 year ago
Major depressive disorder
I was with my ex for 36 years before I foiled for a divorce. We remained close . December 2023 was 1 year for our divorce. He had at least 3 affairs that I proved, I believe he had at least 3 or 4 more that I couldn’t prove. He asked me to move in with him February this year, I did because I thought
I was with my ex for 36 years before I foiled for a divorce. We remained close . December 2023 was 1 year for our divorce. He had at least 3 affairs that I proved, I believe he had at least 3 or 4 more that I couldn’t prove. He asked me to move in with him February this year, I did because I thought
raisin44
in
Anxiety and Depression Support
6 months ago
Radionuclide-Containing Combo Slows Metastatic Prostate Cancer, Improves Survival, MedPage Today September 15, 2024
While this is mostly relevant for those with bone mets, it does indicate better OS with the combo of Xtandi and Xofigo (2 Xs are better than 1). Several links are available in the article for those who want to dig a bit deeper. ********************************************************************* [
While this is mostly relevant for those with bone mets, it does indicate better OS with the combo of Xtandi and Xofigo (2 Xs are better than 1). Several links are available in the article for those who want to dig a bit deeper. ********************************************************************* [
cujoe
in
Fight Prostate Cancer
16 days ago
Change in inhalers
I'm currently on sertide and being switched over to symbicort. I'm not sure of the dosage etc as need to discuss further with gp. I'm a little concerned as been on seretide for years. When I get switched it triggers flares and I've already had loads of time of work. I work part time. I also think I'm
I'm currently on sertide and being switched over to symbicort. I'm not sure of the dosage etc as need to discuss further with gp. I'm a little concerned as been on seretide for years. When I get switched it triggers flares and I've already had loads of time of work. I work part time. I also think I'm
spookylou
in
Asthma Community Forum
6 months ago
Proton or Photon
Hi all, my wife and I are trying to determine the best choice for my prostate cancer. The biopsy/pet scan showed advanced prostate cancer with spreading to the right seminal vessel and involvement of one lymph node. We have had our first consult, locally, with a radiation (x-ray/photon) Dr. who suggested
Hi all, my wife and I are trying to determine the best choice for my prostate cancer. The biopsy/pet scan showed advanced prostate cancer with spreading to the right seminal vessel and involvement of one lymph node. We have had our first consult, locally, with a radiation (x-ray/photon) Dr. who suggested
Garfield-_1234
in
Advanced Prostate Cancer
1 month ago
combination therapy for ADHD
Does anyone have experience using combination therapy of a stimulant plus a non-stimulant? From what I understand, you take the stimulant in the morning and the non-stimulant in the late afternoon or evening. I recently started using Adderall ir. Having a lot of trouble in the evening and at night
Does anyone have experience using combination therapy of a stimulant plus a non-stimulant? From what I understand, you take the stimulant in the morning and the non-stimulant in the late afternoon or evening. I recently started using Adderall ir. Having a lot of trouble in the evening and at night
starsallover
in
CHADD's Adult ADHD Support
6 months ago
Excessive Sleeping
My husband was diagnosed in early 2020 with MSA. The decline was rapid - he is now on PEG for feeds, intermittent urine catheter, flatus tube for bowel movement, and a tracheotomy with ventilator on at night He has speech therapy, physiotherapy, occupational therapy that fills up his days However
My husband was diagnosed in early 2020 with MSA. The decline was rapid - he is now on PEG for feeds, intermittent urine catheter, flatus tube for bowel movement, and a tracheotomy with ventilator on at night He has speech therapy, physiotherapy, occupational therapy that fills up his days However
binnyrox
in
Multiple System Atrophy Trust
6 months ago
Protein discovery could help solve prostate cancer drug resistance Date:January 22, 2024 Source:Washington State University
I found this information while researching my husband's PSA rising issues. Found it interesting and want to share. Click on link to read the entire article https://www.sciencedaily.com/ Protein discovery could help solve prostate cancer drug resistance Date: January 22, 2024 Source: Washington
I found this information while researching my husband's PSA rising issues. Found it interesting and want to share. Click on link to read the entire article https://www.sciencedaily.com/ Protein discovery could help solve prostate cancer drug resistance Date: January 22, 2024 Source: Washington
MsHope
in
Advanced Prostate Cancer
6 months ago
Feeling paranoid
I'm at group therapy and I'm feeling really paranoid right now. More than usual. I'm afraid that someone will notice my paranoia and shame me for it ...thoughts?
I'm at group therapy and I'm feeling really paranoid right now. More than usual. I'm afraid that someone will notice my paranoia and shame me for it ...thoughts?
EricJones
in
Anxiety and Depression Support
6 months ago
Circulating Lipid Profiles Associated With Resistance to Androgen Deprivation Therapy in Localized Prostate Cancer
Circulating Lipid Profiles Associated With Resistance to Androgen Deprivation Therapy in Localized Prostate Cancer Authors: Hui-Ming Lin, PhD https://orcid.org/0000-0003-4892-6008, Xiaoyu Yang, MS https://orcid.org/0009-0001-0035-9289, Margaret M. Centenera, PhD https://orcid.org/0000-0002-2206-0632
Circulating Lipid Profiles Associated With Resistance to Androgen Deprivation Therapy in Localized Prostate Cancer Authors: Hui-Ming Lin, PhD https://orcid.org/0000-0003-4892-6008, Xiaoyu Yang, MS https://orcid.org/0009-0001-0035-9289, Margaret M. Centenera, PhD https://orcid.org/0000-0002-2206-0632
podsart
in
Advanced Prostate Cancer
2 months ago
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