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Ketogenic diet alters the epigenetic and immune landscape of prostate cancer to overcome resistance to immune checkpoint blockade therapy.
Overall, this strikes me as too hypothetical for us to apply, but what do I know? "Overall, these findings illuminate a potential clinical path of using HDACi and optimized KD regimens to enhance ICB therapy for PCa." HDACi = histone deacetylase inhibitor [To date, four HDAC inhibitors, Vorinostat
Overall, this strikes me as too hypothetical for us to apply, but what do I know? "Overall, these findings illuminate a potential clinical path of using HDACi and optimized KD regimens to enhance ICB therapy for PCa." HDACi = histone deacetylase inhibitor [To date, four HDAC inhibitors, Vorinostat
cigafred
in
Fight Prostate Cancer
2 months ago
breathing and health anxiety
Hi all. Much like yourselves it’s a long dotted history with IBS. I’m back dealing with a bout following a stomach bug and work stress. My whole system locked up and slowly became almost unbearable. This time it’s feeling as if my breathing is being placed under pressure as I’m so bloated. The odd times
Hi all. Much like yourselves it’s a long dotted history with IBS. I’m back dealing with a bout following a stomach bug and work stress. My whole system locked up and slowly became almost unbearable. This time it’s feeling as if my breathing is being placed under pressure as I’m so bloated. The odd times
Loftytopping
in
IBS Network
2 months ago
is this cancer?
i’ve posted on here once for a scare, i’m back again. i’m 24 years old, and my poop has just not been super normal since i have had the thought it could be colon cancer. i have a spot on my lower left abdominal area, right below belly button, i assumed it to be a hernia. my doctor sent me for an ultrasound
i’ve posted on here once for a scare, i’m back again. i’m 24 years old, and my poop has just not been super normal since i have had the thought it could be colon cancer. i have a spot on my lower left abdominal area, right below belly button, i assumed it to be a hernia. my doctor sent me for an ultrasound
imscaredofcancer
in
Colon Cancer Connected
2 months ago
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New diagnosis
I was just diagnosed with fibromyalgia. Four years ago, I was diagnosed with Giant Cell Arteritis and, about 2 years later, Polymyalgia Rheumatica. My life has drastically changed between the pain and total exhaustion. Any words of advice would be most welcome.
I was just diagnosed with fibromyalgia. Four years ago, I was diagnosed with Giant Cell Arteritis and, about 2 years later, Polymyalgia Rheumatica. My life has drastically changed between the pain and total exhaustion. Any words of advice would be most welcome.
Miacaro45
in
Fibromyalgia Action UK
2 months ago
Update
I’m now down to 15mg and my stomach is still swollen but cause seems to be Serositis. My pleural effusion are 200/300mls left side and zero right side with now minimal around pericardial so steroids are definitely working indicating cause is definitely autoimmune and possibly PMR . I still don’t feel
I’m now down to 15mg and my stomach is still swollen but cause seems to be Serositis. My pleural effusion are 200/300mls left side and zero right side with now minimal around pericardial so steroids are definitely working indicating cause is definitely autoimmune and possibly PMR . I still don’t feel
Numptybrain
in
PMRGCAuk
2 months ago
A Bladder Cancer Update.
I got a telephone call early this morning, I was still in bed. Was a woman offering me a place in a Private Hospital for A 'FLEXY CYSTOSCOPY' Good news but the hospital was miles away in Preston, in fact the other side. So I asked her could I not get in at my local hospital - She then started talking
I got a telephone call early this morning, I was still in bed. Was a woman offering me a place in a Private Hospital for A 'FLEXY CYSTOSCOPY' Good news but the hospital was miles away in Preston, in fact the other side. So I asked her could I not get in at my local hospital - She then started talking
Ern007
in
Lung Conditions Community Forum
6 months ago
Failed on Piqray... off to xeloda I go....
hi friends... so looks like my time piqray is coming to an end... latest pet scan showed a few more spots on liver! I only got 4 months out of it which I guess anytime is better than nothing' o to xeloda I go..... has anyone been on this med and can anyone give me some advice or any side effects they
hi friends... so looks like my time piqray is coming to an end... latest pet scan showed a few more spots on liver! I only got 4 months out of it which I guess anytime is better than nothing' o to xeloda I go..... has anyone been on this med and can anyone give me some advice or any side effects they
DianaSav
in
SHARE Metastatic Breast Cancer
6 months ago
Mother diagnosed with HG Ovarian cancer. Current Chemo not fully responding (reocurrence). Need suggestions/Guidance - Alternate treatments
My Mother was diagnosed with Ovarian Cancer (high grade Serous Carcinoma) in January 2022. Started Chemo in Feb, 2022(medicine used- Inj Paclitaxel (80 mg/ m2) (D1, D8 q 21 days) + Inj Carboplatin (AUC 5)(D1q3) and by April 2022 CA 125 was 9. Got a Full Hysterectomy surgery and received Hipec chemotherapy
My Mother was diagnosed with Ovarian Cancer (high grade Serous Carcinoma) in January 2022. Started Chemo in Feb, 2022(medicine used- Inj Paclitaxel (80 mg/ m2) (D1, D8 q 21 days) + Inj Carboplatin (AUC 5)(D1q3) and by April 2022 CA 125 was 9. Got a Full Hysterectomy surgery and received Hipec chemotherapy
akhilsalwan
in
My Ovacome
6 months ago
Happy New Year
I'm well and coming up to first anniversary of total hysterectomy for grade 1b ovarian cancer. No treatment just 3 monthly follow ups with CA125. I am very emotional and feeling like a bit of a fraud for not just being very grateful that I am still here.Thanks
I'm well and coming up to first anniversary of total hysterectomy for grade 1b ovarian cancer. No treatment just 3 monthly follow ups with CA125. I am very emotional and feeling like a bit of a fraud for not just being very grateful that I am still here.Thanks
10Ronnies
in
My Ovacome
6 months ago
Polyneuropathy.
I treat my polyneuropathy with B6 and B12. GracePV shared their experience with B6, B12 nd B1. This inspired me to revisit my self treatment of my polyneuropathy. I came across information about Benfotiamine which is similar to Thiamine Hydrochloride and Thiamine Nitrate. There are indications
I treat my polyneuropathy with B6 and B12. GracePV shared their experience with B6, B12 nd B1. This inspired me to revisit my self treatment of my polyneuropathy. I came across information about Benfotiamine which is similar to Thiamine Hydrochloride and Thiamine Nitrate. There are indications
WIZARD6787
in
Pernicious Anaemia Society
2 months ago
Where's the fire in delaying/pausing chemo?
3 weeks ago I started chemo with the Cabazitaxel/Carboplatin combination (I'd rather not name the hospital for now) I had a bad reaction to the first infusion (it turned out that I had an undetected infection, so my immunity was rock-bottom) As a result of that experience (10 days in hospital, wiped
3 weeks ago I started chemo with the Cabazitaxel/Carboplatin combination (I'd rather not name the hospital for now) I had a bad reaction to the first infusion (it turned out that I had an undetected infection, so my immunity was rock-bottom) As a result of that experience (10 days in hospital, wiped
CrocodileShoes
in
Fight Prostate Cancer
6 months ago
"Gut Dysbiosis in Irritable Bowel Syndrome: A Narrative Review on Correlation with Disease Subtypes and Novel Therapeutic Implications"
Research. Source: https://www.mdpi.com/2076-2607/11/10/2369
Abstract
"Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder characterized by chronic abdominal pain and altered bowel habits. It can be subclassified in different subtypes according to the main clinical
Research. Source: https://www.mdpi.com/2076-2607/11/10/2369
Abstract
"Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder characterized by chronic abdominal pain and altered bowel habits. It can be subclassified in different subtypes according to the main clinical
Meleber
in
IBS Network
2 months ago
Weird tingling (not just peripheral neuropathy)
Happy New Year to fellow warriors - I hope for your continued good health as we engage in common cause against our common foe. I start the New Year with an odd query: I'm now on Day 21 of a Cabazitaxel/Carboplatin combination chemo. I was due to have infusion #2 today, but because of a bad reaction,
Happy New Year to fellow warriors - I hope for your continued good health as we engage in common cause against our common foe. I start the New Year with an odd query: I'm now on Day 21 of a Cabazitaxel/Carboplatin combination chemo. I was due to have infusion #2 today, but because of a bad reaction,
CrocodileShoes
in
Fight Prostate Cancer
6 months ago
Invasive Breast Cancer her 2 P+ E+1 lymph node Metastatic spread after chemo & Mastectomy
Hi Guys, I’m struggling here. . I was diagnosed with Invasive Breast Cancer her 2 , P+ E+ positive. I had docetaxel carboplatin and ohesgo and straight in for a single mastectomy and a couple of lymph nodes out. 1 came back with a 4mm Metastatic spread after chemo and 3 weeks ago I had a full
Hi Guys, I’m struggling here. . I was diagnosed with Invasive Breast Cancer her 2 , P+ E+ positive. I had docetaxel carboplatin and ohesgo and straight in for a single mastectomy and a couple of lymph nodes out. 1 came back with a 4mm Metastatic spread after chemo and 3 weeks ago I had a full
GillyGangGong
in
SHARE Metastatic Breast Cancer
6 months ago
scabies won´t go away, help
Hello, have anybody scabies won´t go away? I have it for 2 years now and it is horrobil. I try everything (all chemicals / medicine, all natural things with vaseline and sulfur and with all ethereal oils, with enzyme, with borax, CDL, bleech and so on outside , mixed it in all ways. and inside with
Hello, have anybody scabies won´t go away? I have it for 2 years now and it is horrobil. I try everything (all chemicals / medicine, all natural things with vaseline and sulfur and with all ethereal oils, with enzyme, with borax, CDL, bleech and so on outside , mixed it in all ways. and inside with
Massio
in
BASHH
2 months ago
Vitamin D dropped again
Hi everyone I had my Vitamin tested in January and I was deficient. January 2024: Vitamin D deficient (Vitamin D: 27.4 ng/ml (Low) ….(30-100) I decided to sit outside instead of supplement (weather has been very mild) I just got my results for April 2024 and Im worse off… April 2024: Vitamin
Hi everyone I had my Vitamin tested in January and I was deficient. January 2024: Vitamin D deficient (Vitamin D: 27.4 ng/ml (Low) ….(30-100) I decided to sit outside instead of supplement (weather has been very mild) I just got my results for April 2024 and Im worse off… April 2024: Vitamin
Batty1
in
Thyroid UK
2 months ago
Thank you to all who helped ref Alendronic Acid
I am pleased to tell you, following my email to my Rheumatology Team, I had a telephone call from my Consultant who was very understanding relating to my unwillingness to take Alendronic Acid as prescribed and issued. Your repsonses gave me the courage I needed to continue objecting to it. He is
I am pleased to tell you, following my email to my Rheumatology Team, I had a telephone call from my Consultant who was very understanding relating to my unwillingness to take Alendronic Acid as prescribed and issued. Your repsonses gave me the courage I needed to continue objecting to it. He is
Knip
in
Bone Health and Osteoporosis UK
8 months ago
Betaine HCL
Good day Friends. I am considering trying Betaine, I have Autoimmune Gastritis. Have been having what I think is gas pain, it can be in left chest, upper right quadrant, right chest area, it moves around. Sometimes sits just before lower chest area. Sometimes its s stabbing pain in chest/abdomen
Good day Friends. I am considering trying Betaine, I have Autoimmune Gastritis. Have been having what I think is gas pain, it can be in left chest, upper right quadrant, right chest area, it moves around. Sometimes sits just before lower chest area. Sometimes its s stabbing pain in chest/abdomen
Canadian77
in
Pernicious Anaemia Society
2 months ago
PA/stomach pain
Hi all, I’m so grateful for all of your support as I’ve started down this road. Got diagnosed with PA/AIG in the fall via an endoscopy. I am on B12 injections. My stomach pain has gotten steadily worse instead of better even though I am on a very restrictive diet. Is there any reason for me to believe
Hi all, I’m so grateful for all of your support as I’ve started down this road. Got diagnosed with PA/AIG in the fall via an endoscopy. I am on B12 injections. My stomach pain has gotten steadily worse instead of better even though I am on a very restrictive diet. Is there any reason for me to believe
Lhood08
in
Pernicious Anaemia Society
2 months ago
Genetic testing and Second Opinion – A result!
Following on from my post last week about docetaxel not working, I had a frank conversation with my MO during which I said I strongly believe that genetic testing of my liver biopsy sample should be the next step and after some debate, to my surprise, he agreed and has put through the request. It’s still
Following on from my post last week about docetaxel not working, I had a frank conversation with my MO during which I said I strongly believe that genetic testing of my liver biopsy sample should be the next step and after some debate, to my surprise, he agreed and has put through the request. It’s still
Benkaymel
in
Advanced Prostate Cancer
6 months ago
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