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Levodopa / Carbidopa / Entacapone
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Mucuna dosage help please
Can any of you bright folk help me out with the dosage here please. I take this mucuna powder 99.6% l-dopa. I find it really helpful. (See photo) Am I right in assuming that 1/8 tsp is 500mg which is equivalent to 5 senimet tabs of 25/100? Surely that can’t be right! What am I missing here??? (And
Can any of you bright folk help me out with the dosage here please. I take this mucuna powder 99.6% l-dopa. I find it really helpful. (See photo) Am I right in assuming that 1/8 tsp is 500mg which is equivalent to 5 senimet tabs of 25/100? Surely that can’t be right! What am I missing here??? (And
saraoutwest
in
Cure Parkinson's
3 years ago
Levodopa
How safe is Levodopa? I'm looking for a recent post on side effects of Levodopa? What are the side effects? What symptoms does it improve? How many people in this group are taking Levodopa and have h ad positive results Thanks for your help
How safe is Levodopa? I'm looking for a recent post on side effects of Levodopa? What are the side effects? What symptoms does it improve? How many people in this group are taking Levodopa and have h ad positive results Thanks for your help
Smittybear7
in
Cure Parkinson's
3 years ago
Statin use may have a detrimental effect (faster increase in levodopa & dementia conversion )
"This study suggests that statin use may have a detrimental effect on baseline nigrostriatal dopamine degeneration and long-term outcomes in patients with Parkinson’s disease." https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awab292/6339771
"This study suggests that statin use may have a detrimental effect on baseline nigrostriatal dopamine degeneration and long-term outcomes in patients with Parkinson’s disease." https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awab292/6339771
Hidden
in
Cure Parkinson's
3 years ago
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Advise on drug s
Which drug would compliment carbidopa-levodopa to make it last long with the least side effects
Which drug would compliment carbidopa-levodopa to make it last long with the least side effects
akgirlsrock
in
Cure Parkinson's
3 years ago
Balance with dopamine / choline receptors
Parkinson do we need to supplement choline or do we have to much choline, if we are not making dopamine will it cause to much choline and is that what causes tremors? I tried entacapone for 4 days and gave me dysknesia, I even cut pill in half, it seemed worse in the morning , I'm thinking my ER night
Parkinson do we need to supplement choline or do we have to much choline, if we are not making dopamine will it cause to much choline and is that what causes tremors? I tried entacapone for 4 days and gave me dysknesia, I even cut pill in half, it seemed worse in the morning , I'm thinking my ER night
akgirlsrock
in
Cure Parkinson's
3 years ago
Typical med progression?
My friend started taking l-dopa within the past year. She works fulltime and her workplace isn't aware of her diagnosis. Currently she's taking 8 Sinemet 100mg daily, plus 3 or 4 Rytary 145mg. She also takes sleeping medication, and botox for curled toes. She's reading articles on DBS. Any advice
My friend started taking l-dopa within the past year. She works fulltime and her workplace isn't aware of her diagnosis. Currently she's taking 8 Sinemet 100mg daily, plus 3 or 4 Rytary 145mg. She also takes sleeping medication, and botox for curled toes. She's reading articles on DBS. Any advice
genesurf
in
Cure Parkinson's
3 years ago
B6 recommended with carbidopa levodopa.
I am 2.5 years dx with Pd and just started carbidopa levodopa. It helped quite a bit and took b6 (for depression) this morning and was amazed at how good I felt. Like I was 100 percent normal. I took too much as I have read. ParkBear was very in-depth but I haven’t talked to my neurologist about it
I am 2.5 years dx with Pd and just started carbidopa levodopa. It helped quite a bit and took b6 (for depression) this morning and was amazed at how good I felt. Like I was 100 percent normal. I took too much as I have read. ParkBear was very in-depth but I haven’t talked to my neurologist about it
38yroldmale
in
Cure Parkinson's
3 years ago
Carbidopa/Levodopa Success Stories
Perhaps you saw Jim's recent excellent post "The Value Of Carbidopa Levodopa Demonstrated in Two Signatures" at https://healthunlocked.com/cure-parkinsons/posts/146518581/the-value-of-carbidopa-levodopa-demonstrated-in-two-signatures How has carbidopa/levodopa helped you? You can share your carbidopa
Perhaps you saw Jim's recent excellent post "The Value Of Carbidopa Levodopa Demonstrated in Two Signatures" at https://healthunlocked.com/cure-parkinsons/posts/146518581/the-value-of-carbidopa-levodopa-demonstrated-in-two-signatures How has carbidopa/levodopa helped you? You can share your carbidopa
Hidden
in
Cure Parkinson's
3 years ago
The Value Of Carbidopa Levodopa Demonstrated in Two Signatures
One of the first decisions a PwP must make is when (or whether) to begin taking medication. There is no correct answer and we all know how PD varies from person to person. I held off for 2 1/2 years after my diagnosis, but a relatively minor event today caused me to pause and think about how well sinemet
One of the first decisions a PwP must make is when (or whether) to begin taking medication. There is no correct answer and we all know how PD varies from person to person. I held off for 2 1/2 years after my diagnosis, but a relatively minor event today caused me to pause and think about how well sinemet
jimcaster
in
Cure Parkinson's
3 years ago
Equivalence between C/L meds and Mucuna Pruriens.
Does anyone have any knowledge or information on the enhancing effect of carbidopa in Sinemet-type medications compared to levodopa found in Mucuna? I believe I've read somewhere 4 or 5 times, is that approximately right? Might a standard 100/25 C/L tablet be as powerful as 500mg of levodopa from mucuna
Does anyone have any knowledge or information on the enhancing effect of carbidopa in Sinemet-type medications compared to levodopa found in Mucuna? I believe I've read somewhere 4 or 5 times, is that approximately right? Might a standard 100/25 C/L tablet be as powerful as 500mg of levodopa from mucuna
puretone
in
Cure Parkinson's
3 years ago
Side effects of levodopa. And you thought that your imagination was running wild.
https://www.drugs.com/sfx/sinemet-side-effects.html I recognize many of them as questions to healthunlocked. I have been dealing with some of them myself. Mary
https://www.drugs.com/sfx/sinemet-side-effects.html I recognize many of them as questions to healthunlocked. I have been dealing with some of them myself. Mary
parkie13
in
Cure Parkinson's
3 years ago
Would Adding 10,000 IU a day of D3 would be a good thing to complement my Niacin 250 mg a day? Maybe NOT
Sometimes I'm Stupid. This is a re-write of my post extolling the virtues of vitamin D3 based on misreading a study and thinking down was up and left was right. I would just delete it but some people have seen it and I want the correction to be here. This is the trial from 2016 that had me excited:
Sometimes I'm Stupid. This is a re-write of my post extolling the virtues of vitamin D3 based on misreading a study and thinking down was up and left was right. I would just delete it but some people have seen it and I want the correction to be here. This is the trial from 2016 that had me excited:
Bolt_Upright
in
Cure Parkinson's
3 years ago
Stopping meds
I wanted to see what the effects might be. How soon does the body deteriorate after stopping L-Dopa? I stopped Rytary 9 days ago. I've had two mild bouts of dizziness. And as can be seen on this shopping list my hand writing has gone from bad to worse. I wondered if there might be withdrawal
I wanted to see what the effects might be. How soon does the body deteriorate after stopping L-Dopa? I stopped Rytary 9 days ago. I've had two mild bouts of dizziness. And as can be seen on this shopping list my hand writing has gone from bad to worse. I wondered if there might be withdrawal
kaypeeoh
in
Cure Parkinson's
3 years ago
New extended release Levodopa formulation
Amneal Announces Positive Topline Results from Pivotal Phase 3 RISE-PD Clinical Trial of IPX-203 in Patients with Parkinson’s Disease Who Experience Motor Fluctuations. IPX-203 (CD/LD extended-release capsules) In individuals who experience motor fluctuations; have 0.53 more hours of “Good On” time.
Amneal Announces Positive Topline Results from Pivotal Phase 3 RISE-PD Clinical Trial of IPX-203 in Patients with Parkinson’s Disease Who Experience Motor Fluctuations. IPX-203 (CD/LD extended-release capsules) In individuals who experience motor fluctuations; have 0.53 more hours of “Good On” time.
Buckholt
in
Cure Parkinson's
3 years ago
Opicapone: A third generation COMT inhibitor
Opicapone is used once daily as adjunctive to levodopa/carbidopa to reduce “off” periods in patients with Parkinson’s disease. • In clinical trials BIPARK I and II, 50 mg of opicapone once daily was shown to be noninferior to entacapone and reduced the mean off time by about 50 min when compared to
Opicapone is used once daily as adjunctive to levodopa/carbidopa to reduce “off” periods in patients with Parkinson’s disease. • In clinical trials BIPARK I and II, 50 mg of opicapone once daily was shown to be noninferior to entacapone and reduced the mean off time by about 50 min when compared to
Farooqji
in
Cure Parkinson's
3 years ago
How long before levodopa stops working in Parkinson’s disease?
After taking levodopa for some time, typically a few years, patients may begin to experience a wearing off period, when symptoms return before it's time for their next dose of levodopa. This is also referred to as "off time.” Off time is common, and according to patient surveys, around half of patients
After taking levodopa for some time, typically a few years, patients may begin to experience a wearing off period, when symptoms return before it's time for their next dose of levodopa. This is also referred to as "off time.” Off time is common, and according to patient surveys, around half of patients
Farooqji
in
Cure Parkinson's
3 years ago
? for Entacapone users
For those who have used entacapone, did you find it caused you fatigue?
For those who have used entacapone, did you find it caused you fatigue?
Zardoz
in
Cure Parkinson's
3 years ago
PART 2 : Reversing Memory Deficits And Senior Moments In A 78 Year Old
In case you missed part 1, here is a link to that post which explains how this supplement plan helped a person with memory issues : https://healthunlocked.com/cure-parkinsons/posts/144327704/part-1-reversing-memory-deficits-and-senior-moments-in-a-78-year-old The reason I am writing this second part
In case you missed part 1, here is a link to that post which explains how this supplement plan helped a person with memory issues : https://healthunlocked.com/cure-parkinsons/posts/144327704/part-1-reversing-memory-deficits-and-senior-moments-in-a-78-year-old The reason I am writing this second part
chartist
in
Cure Parkinson's
3 years ago
Check Out the Stack on This Guy!
Balancing the Apoptotic Switch – From Cancer to Parkinson’s Disease - 2016 https://www.jscimedcentral.com/DrugDesign/drugdesign-4-1030.pdf I Got Duped by a fake journal!! Thanks Hikoi! http://flakyj.blogspot.com/2017/01/jscimed-central-jsm.html JSciMed Central aims to harbor the journal free from the
Balancing the Apoptotic Switch – From Cancer to Parkinson’s Disease - 2016 https://www.jscimedcentral.com/DrugDesign/drugdesign-4-1030.pdf I Got Duped by a fake journal!! Thanks Hikoi! http://flakyj.blogspot.com/2017/01/jscimed-central-jsm.html JSciMed Central aims to harbor the journal free from the
Bolt_Upright
in
Cure Parkinson's
3 years ago
More Bee Stuff: Synergistic action of propolis with levodopa in the management of Parkinsonism in Drosophila melanogaster - 2020
http://idr.kab.ac.ug/bitstream/handle/20.500.12493/439/synergistic-action-of-propolis-with-levodopa-in-the-management-of-parkinsonism-indrosophila-.pdf?sequence=1&isAllowed=y The study showed that the administration of ethanolic extract of propolis (500 mg/mL) with levodopa (250 mg/kg) not only significantly
http://idr.kab.ac.ug/bitstream/handle/20.500.12493/439/synergistic-action-of-propolis-with-levodopa-in-the-management-of-parkinsonism-indrosophila-.pdf?sequence=1&isAllowed=y The study showed that the administration of ethanolic extract of propolis (500 mg/mL) with levodopa (250 mg/kg) not only significantly
Bolt_Upright
in
Cure Parkinson's
3 years ago
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