In case you missed part 1, here is a link to that post which explains how this supplement plan helped a person with memory issues :
The reason I am writing this second part is twofold, one is that when I wrote the original post, it was very specific to my friend's condition which involved more than memory deficits that she wanted to try and improve, so not 100% specific for memory, but interest in this post is for the memory aspect of this supplement regimen. So in order to focus more specifically on memory improvement, I am changing this supplement regimen based on reader interest as well as potentially improving memory benefit and elapsed time to benefit as well as new research.
So in this new regimen, I still want to keep 5 supplements, but I want to decrease the time to test each supplement, rearrange the order, drop one supplement and add a new supplement.
Here is the revised regimen :
1. Vinpocetine @ 30 mg/day + Vitamin D @ 5000 IU/day up to 10,000 IU/day
2. Lithium Orotate 5 mg/day up to 20 mg/day if needed
3. Citicoline 500 mg/day up to 1,000mg/day
4. Melatonin 10 mg/night up to tolerance if needed
If another friend were to want to test this regimen, I would suggest the above order and I would suggest testing each number for 4 to 6 weeks before adding the next number to make sure that they will tolerate each number before adding the next. If they go with a 6 week test for each number, that is 24 weeks to test the full regimen and results should be apparent by 24 weeks or 6 months which is significantly quicker that the original regimen. If they only test each number for one month, it will take 4 months to test all numbers and some benefit should be noticeable by 4 months which again, is substantially quicker than the original regimen.
The reason I am dropping AMLA extract is because it was focused more toward other health issues that my friend was having and less toward memory improvement. The reason I am adding Citicoline is because the research has evolved since I wrote part 1 and I think Citicoline represents a meaningful advancement in memory enrichment that is worth incorporating in a good memory supplement regimen and an effective memory regimen should not be static and should adapt as the research in the field of memory expands. I am adapting this regimen to reflect the current science and to significantly improve potential response time to this regimen. The following new (August 2021), randomized, placebo controlled, double blind trial using Citicoline in trial participants for 12 weeks represents very good progress in the science of memory enrichment, though it has gotten no significant fanfare whatsoever.
>>>>>>> A warning regarding Citicoline in PwP <<<<<<<
Although this new study above suggests that Citicoline is likely useful in terms of memory improvement, Citicoline is also suggested to be useful in promotion of levodopa and in PwP, that means that the addition of Citicoline to your C/L regimen may result in too much dopamine, which can lead to issues such as seen when the C/L dose is too high and in fact some PwP have been able to decrease their C/L dose after adding Citicoline to their daily C/L regimen. For this reason, you should seek the advice and direction of your neurologist or movement disorder specialist before adding Citicoline to your PD regimen.
Although this regimen is more memory specific, it too should offer other health benefits over time. These supplements all have at least a very good safety profile at the doses used.