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Levodopa / Carbidopa / Entacapone
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Vinpocetine regulates levels of circulating TLRs in Parkinson's disease patients 2019
I started today asking "what can I remove from my stack?" And of course, now I am probably adding to my stack: https://www.researchgate.net/publication/328251573_Vinpocetine_regulates_levels_of_circulating_TLRs_in_Parkinson%27s_disease_patients As close as I can tell, it looks like the dosing was 20
I started today asking "what can I remove from my stack?" And of course, now I am probably adding to my stack: https://www.researchgate.net/publication/328251573_Vinpocetine_regulates_levels_of_circulating_TLRs_in_Parkinson%27s_disease_patients As close as I can tell, it looks like the dosing was 20
Bolt_Upright
in
Cure Parkinson's
3 years ago
Dose Adjustment
My Dose Carbidopa levodopa IR 25/100 (2) Thiamine hcl 4 grams daily. Tentatively Carbidopa levodopa IR 25/100 (1) Thiamine hcl 6 grams daily.
My Dose Carbidopa levodopa IR 25/100 (2) Thiamine hcl 4 grams daily. Tentatively Carbidopa levodopa IR 25/100 (1) Thiamine hcl 6 grams daily.
Hidden
in
Cure Parkinson's
3 years ago
Citicoline as Adjuvant Therapy in Parkinson's Disease: A Systematic Review 2017
Findings A total of 7 studies (2 crossover, 3 randomized controlled, and 2 open prospective studies) were included. Despite the varied outcome tools, this review found that patients with PD who were taking citicoline had significant improvement in rigidity, akinesia, tremor, handwriting, and speech.
Findings A total of 7 studies (2 crossover, 3 randomized controlled, and 2 open prospective studies) were included. Despite the varied outcome tools, this review found that patients with PD who were taking citicoline had significant improvement in rigidity, akinesia, tremor, handwriting, and speech.
Bolt_Upright
in
Cure Parkinson's
3 years ago
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Surprise, surprise. "When should you start medication therapy for Parkinson's disease?" as per THE PARKINSON'S FOUNDATION.
"The most important factor in initiating medications for an individual patient is whether Parkinson’s symptoms are affecting quality of life, (read; interfering with...) or alternatively whether symptoms are affecting work performance." Read; not automatically at the time of diagnosis. https://www.parkinson.org
"The most important factor in initiating medications for an individual patient is whether Parkinson’s symptoms are affecting quality of life, (read; interfering with...) or alternatively whether symptoms are affecting work performance." Read; not automatically at the time of diagnosis. https://www.parkinson.org
MBAnderson
in
Cure Parkinson's
3 years ago
How Mucuna Pruriens can help body builders !
https://www.healthessentialsdirect.co.uk/blogs/news/mucuna-pruriens-muscle-building
https://www.healthessentialsdirect.co.uk/blogs/news/mucuna-pruriens-muscle-building
Thal
in
Cure Parkinson's
3 years ago
Why Does High Dose Thiamine Work?
I like to keep challenging the items in my stack. HDT is in my stack. I believe in HDT. But why? So far I trust HDT because of the results from Dr Constantini and the testimonials. Time to look for some science: Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children
I like to keep challenging the items in my stack. HDT is in my stack. I believe in HDT. But why? So far I trust HDT because of the results from Dr Constantini and the testimonials. Time to look for some science: Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children
Bolt_Upright
in
Cure Parkinson's
3 years ago
Where to from here?
Writing to you from New Zealand where thus far we have had no contact with other PSP sufferers. In late 2019 my wife (80yrs) had significant weight loss and tremor. Was originally diagnosed with BET (Benign Essential Tremor). Some months later this was changed to Parkinson's. Prescribed levodopa with
Writing to you from New Zealand where thus far we have had no contact with other PSP sufferers. In late 2019 my wife (80yrs) had significant weight loss and tremor. Was originally diagnosed with BET (Benign Essential Tremor). Some months later this was changed to Parkinson's. Prescribed levodopa with
BlairWit
in
PSP Association
3 years ago
Sinemet v carbo levodopa g
Sinemet is the Origina make/brand for levodopa and I have always had this made by Merrick Sharp Dohme Recently in found to my cost that it longer under special licence and it can be made by anyone now, but I was unaware that they would have such a different effect on me. They don’t work well at
Sinemet is the Origina make/brand for levodopa and I have always had this made by Merrick Sharp Dohme Recently in found to my cost that it longer under special licence and it can be made by anyone now, but I was unaware that they would have such a different effect on me. They don’t work well at
Connie18
in
Cure Parkinson's
3 years ago
Associations between osteoporosis and drug exposure: a post-marketing study of the World Health Organization pharmacovigilance database
This is a comprehensive paper on the impact of medicines on bone density, osteoporosis and fracture. Thyroid hormones are listed but their impact appears considerably lower than for Proton Pump Inhibitors (PPIs), Methotrexate, Steroids, Hydroxychloroquine, and others. It is also often mentioned here
This is a comprehensive paper on the impact of medicines on bone density, osteoporosis and fracture. Thyroid hormones are listed but their impact appears considerably lower than for Proton Pump Inhibitors (PPIs), Methotrexate, Steroids, Hydroxychloroquine, and others. It is also often mentioned here
helvella
Thyroid UK
in
Thyroid UK
3 years ago
Ropinerole and Muncuna Pruriens
Has anyone had any experience of combining Ropinerole with high strength Mucuna Pruriens L-Dopa extract capsules food supplement? I am on 0.5mg of Ropinerole and reluctant to increase the dosage due to augmentation so I have just started to take Muncuna early in the evening followed by Ropinerole before
Has anyone had any experience of combining Ropinerole with high strength Mucuna Pruriens L-Dopa extract capsules food supplement? I am on 0.5mg of Ropinerole and reluctant to increase the dosage due to augmentation so I have just started to take Muncuna early in the evening followed by Ropinerole before
dahon
in
Restless Legs Syndrome
3 years ago
REFINING MY PREVIOUS QUESTION (,,, food for thought): should it be preferable in PSP to take phenylalanine instead of tyrosin supplements?
REFINING MY QUESTION (,,, food for thought...) Tyrosine is a dopamine percursor and as such appears to be a good option for supplementation in PSP. “Tyrosine hydroxylase” is the enzyme responsible for catalyzing the conversion of the amino acid L- tyrosine to L-DOPA. Tyrosine can also be made of phenylalanine
REFINING MY QUESTION (,,, food for thought...) Tyrosine is a dopamine percursor and as such appears to be a good option for supplementation in PSP. “Tyrosine hydroxylase” is the enzyme responsible for catalyzing the conversion of the amino acid L- tyrosine to L-DOPA. Tyrosine can also be made of phenylalanine
BluesHealer
in
PSP Association
3 years ago
Mannitol and B1: What’s going on?
Last September, my hwp for 16 years, started mannitol. Over the next months, this gradually allowed him to reduce his dopamine meds, first eliminating the Neupro patch, then gradually eliminating Rytary. He has cognitive impairment and too much of those 2 meds would cause hallucinations. But dialing
Last September, my hwp for 16 years, started mannitol. Over the next months, this gradually allowed him to reduce his dopamine meds, first eliminating the Neupro patch, then gradually eliminating Rytary. He has cognitive impairment and too much of those 2 meds would cause hallucinations. But dialing
LeharLover62
in
Cure Parkinson's
3 years ago
Back to Melatonin - Dosing?
I won't go as deep as Art does on Melatonin, but am picking up on a point Art makes often: Dosing! I read all these papers and frankly skim over a lot. Today somebody on FB reposted one of my favorites: 2021 - Melatonin as a Chronobiotic and Cytoprotective Agent in Parkinson’s Disease https://www.ncbi.nlm.nih.gov
I won't go as deep as Art does on Melatonin, but am picking up on a point Art makes often: Dosing! I read all these papers and frankly skim over a lot. Today somebody on FB reposted one of my favorites: 2021 - Melatonin as a Chronobiotic and Cytoprotective Agent in Parkinson’s Disease https://www.ncbi.nlm.nih.gov
Bolt_Upright
in
Cure Parkinson's
3 years ago
ARE YOU A NON TREMOR DOMINANT PD PATIENT WITH DYSKINESIA? IF SO, PLEASE HELP.
Hi, your suggestions would help a lot. I am beginning to have dyskinesia more frequently. Mostly worse at night. I take Rytary 3pills 145mg, (8am,12noon,4pm and 8pm). My MDS thinks it is motor fluctuations, caused by uneven plasma level of Levodopa. He suggested that I should add two more pills,
Hi, your suggestions would help a lot. I am beginning to have dyskinesia more frequently. Mostly worse at night. I take Rytary 3pills 145mg, (8am,12noon,4pm and 8pm). My MDS thinks it is motor fluctuations, caused by uneven plasma level of Levodopa. He suggested that I should add two more pills,
OREOLU
in
Cure Parkinson's
3 years ago
A potential case of remission of Parkinson’s disease
Karishma Smart*, Raymon Durso, Jonathan Morgan and Patrick McNamaraA potential case of remissionof Parkinson’s diseaseDOI 10.1515/jcim-2016 https://mindandculture.org/wordpress6/wp-content/uploads/2018/05/SmartDursoMorganMcNamara-A-Potential-Case-of-Remission-of-Parkinsons-Disease.pdf The patient meditates
Karishma Smart*, Raymon Durso, Jonathan Morgan and Patrick McNamaraA potential case of remissionof Parkinson’s diseaseDOI 10.1515/jcim-2016 https://mindandculture.org/wordpress6/wp-content/uploads/2018/05/SmartDursoMorganMcNamara-A-Potential-Case-of-Remission-of-Parkinsons-Disease.pdf The patient meditates
Bolt_Upright
in
Cure Parkinson's
3 years ago
DO YOU USE MUCUNA P FOR PD?
Hi everyone, do you use Mucuna P for your PD treatment? Do you have dyskinesia before using Mucuna? Did it help decrease or stop the dyskinesia? If you answer YES to all the above questions ,kindly let me know your brand of Mucuna, the % concentration of Levodopa and where to purchase it. Thanks
Hi everyone, do you use Mucuna P for your PD treatment? Do you have dyskinesia before using Mucuna? Did it help decrease or stop the dyskinesia? If you answer YES to all the above questions ,kindly let me know your brand of Mucuna, the % concentration of Levodopa and where to purchase it. Thanks
OREOLU
in
Cure Parkinson's
3 years ago
Gene Therapy Success With Ties to Parkinson’s Disease
I posted this as a reply to Bass of Spade's optimistic post regarding gene therapy, but I think it's worthy of being the subject of a separate post. Gene Therapy Offers Long-Awaited Hope for Children with Rare, Incurable Disorder. Patients with Parkinson’s, Alzheimer’s May Benefit from Novel Treatment
I posted this as a reply to Bass of Spade's optimistic post regarding gene therapy, but I think it's worthy of being the subject of a separate post. Gene Therapy Offers Long-Awaited Hope for Children with Rare, Incurable Disorder. Patients with Parkinson’s, Alzheimer’s May Benefit from Novel Treatment
jimcaster
in
Cure Parkinson's
3 years ago
Sinemet / carbidopa levodopa
“In 1988, the U.S. Food and Drug Administration (FDA) is recommended that the daily dose of Sinemet should not exceed 800 mg per day, and as of 2013, this recommendation has not been revised. In 2018 the labeling of Sinemet recommends not exceeding a levodopa total daily dose of 2,000 mg per day. As
“In 1988, the U.S. Food and Drug Administration (FDA) is recommended that the daily dose of Sinemet should not exceed 800 mg per day, and as of 2013, this recommendation has not been revised. In 2018 the labeling of Sinemet recommends not exceeding a levodopa total daily dose of 2,000 mg per day. As
Hidden
in
Cure Parkinson's
3 years ago
Dopamine agonists or levodopa?
I am 53 and was diagnosed PD 8 years . I am currently on 1/2 spoon of Zandopa and 1/4 Sinemet, 4 times a day. The medication only lasts for about 2 hours, so each day has been a hell for me. I am currently deciding on whether I should go with dopamine agonists first, or I should add more zandopa/ Macuna
I am 53 and was diagnosed PD 8 years . I am currently on 1/2 spoon of Zandopa and 1/4 Sinemet, 4 times a day. The medication only lasts for about 2 hours, so each day has been a hell for me. I am currently deciding on whether I should go with dopamine agonists first, or I should add more zandopa/ Macuna
LauraYu
in
Cure Parkinson's
3 years ago
Plantago ovata husk (psyllium) administration caused a smoothing and homogenization of levodopa absorption
Plantago ovata husk (psyllium) administration caused a smoothing and homogenization of levodopa absorption, providing more stable concentrations and final higher levels, resulting in a great benefit for patients. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139609/
Plantago ovata husk (psyllium) administration caused a smoothing and homogenization of levodopa absorption, providing more stable concentrations and final higher levels, resulting in a great benefit for patients. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139609/
Thal
in
Cure Parkinson's
3 years ago
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