Opicapone: A third generation COMT inhibitor - Cure Parkinson's

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Opicapone: A third generation COMT inhibitor

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Farooqji
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Opicapone is used once daily as adjunctive to levodopa/carbidopa to reduce “off” periods in patients with Parkinson’s disease.

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In clinical trials BIPARK I and II, 50 mg of opicapone once daily was shown to be noninferior to entacapone and reduced the mean off time by about 50 min when compared to placebo.

sciencedirect.com/science/a...

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Farooqji
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tacato

I started treatment with opicapone over a month ago. While it's early yet, I have seen no improvement.

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