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PCNA gene attack -- for solid tumors
Pasted from a publicly avaiilable website A "holy grail" molecule that kills all solid cancer tumors, leaving other cells unaffected, has been developed by scientists. The team at the City of Hope, one of the largest cancer research and treatment organizations in the United States, made the breakthrough
Pasted from a publicly avaiilable website A "holy grail" molecule that kills all solid cancer tumors, leaving other cells unaffected, has been developed by scientists. The team at the City of Hope, one of the largest cancer research and treatment organizations in the United States, made the breakthrough
Derf4223
in
Advanced Prostate Cancer
1 year ago
US names first 10 drugs for Medicare price negotiation
US names first 10 drugs for Medicare price negotiation-By Patrick Wingrove and Michael Erman August 29, 202310:46 AM EDT https://www.reuters.com/business/healthcare-pharmaceuticals/us-name-first-10-drugs-medicare-price-negotiation-2023-08-29/ Aug 29(Reuters) - The Biden administration on Tuesday
US names first 10 drugs for Medicare price negotiation-By Patrick Wingrove and Michael Erman August 29, 202310:46 AM EDT https://www.reuters.com/business/healthcare-pharmaceuticals/us-name-first-10-drugs-medicare-price-negotiation-2023-08-29/ Aug 29(Reuters) - The Biden administration on Tuesday
lankisterguy
Volunteer
in
CLL Support
1 year ago
WOW, noticing today, after some weak days at 5mg prednisone, I am again feeling good and energetic, added meth and hydroxy dropped metformin
I was at 5 a few weeks go, but too hastily dropped and went to 2.5, and on the 3rd day at 2.5 felt terrible. Jumped back to 10 and then 7.5. And since I have gone back to 5, after maybe a week at 5, I am again feeling great, better than I did the last time I was at 5. There are some differences now,
I was at 5 a few weeks go, but too hastily dropped and went to 2.5, and on the 3rd day at 2.5 felt terrible. Jumped back to 10 and then 7.5. And since I have gone back to 5, after maybe a week at 5, I am again feeling great, better than I did the last time I was at 5. There are some differences now,
sdowney717
in
PMRGCAuk
1 year ago
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Bruising, Ozempic, Nausea, Depression, Steroids, Facial Hair. You Name It.
Gang, I am in a downward spiral. 1. Death of son so sad a lot. 2. Steroids for PMR led to diabetes II. Also, two half brothers have diabetes. 3. Doc put me on Ozempicto get my weight down as low as it can be to avoid insulin shots. 4. From lowest dose of Ozem I am still queasy most of the
Gang, I am in a downward spiral. 1. Death of son so sad a lot. 2. Steroids for PMR led to diabetes II. Also, two half brothers have diabetes. 3. Doc put me on Ozempicto get my weight down as low as it can be to avoid insulin shots. 4. From lowest dose of Ozem I am still queasy most of the
Merryfield
in
PMRGCAuk
1 year ago
The depression is so real.
Hello,My story is a very long one so the condensed version is my family was/is very dysfunctional. I have been married three times. My first and second husbands were emotionally and physically abusive. I have been married to my current husband for 23 years. I thought my life was finally to a good
Hello,My story is a very long one so the condensed version is my family was/is very dysfunctional. I have been married three times. My first and second husbands were emotionally and physically abusive. I have been married to my current husband for 23 years. I thought my life was finally to a good
Puppielove
in
Major Depressive Disorder (MDD) Support
1 year ago
Tips needing for insulin use in type 2
My husband has type 2 diabetes now managed with Metformin, Pioglitazone 15gm, Insulin Nova rapid & Lantus.He is feeling stressed because he is not sure how much insulin to inject versus carbs and food eaten. He has a Libre sensor how much variation in levels should there be when he has eaten? Is the
My husband has type 2 diabetes now managed with Metformin, Pioglitazone 15gm, Insulin Nova rapid & Lantus.He is feeling stressed because he is not sure how much insulin to inject versus carbs and food eaten. He has a Libre sensor how much variation in levels should there be when he has eaten? Is the
Whitton6
in
Diabetes Support
1 year ago
Difficulty understanding diet with Insulin
My husband aged 53 has had type 2 diabetes for 10yrs. He is a long-distance truck driver away Monday to Friday. His A1C has been high for a several years. He started insulin in Jan 2023 and does not understand how to maintain his levels which still vary from 9 to over 20 an Hi on his Libre sensor. He
My husband aged 53 has had type 2 diabetes for 10yrs. He is a long-distance truck driver away Monday to Friday. His A1C has been high for a several years. He started insulin in Jan 2023 and does not understand how to maintain his levels which still vary from 9 to over 20 an Hi on his Libre sensor. He
Whitton6
in
Diabetes Support
1 year ago
A few questions for the diabetics here that are on insulin.
I'm a t2 diabetic and have been for over 20 years. Mostly I've kept it under control with A1C around 6, give or take a few. This was with metformin. My CKD has progressed to where I had to stop the metformin. My doctor tried a few other meds but they didn't work. A couple of weeks ago I started
I'm a t2 diabetic and have been for over 20 years. Mostly I've kept it under control with A1C around 6, give or take a few. This was with metformin. My CKD has progressed to where I had to stop the metformin. My doctor tried a few other meds but they didn't work. A couple of weeks ago I started
jodaer
in
Kidney Disease
1 year ago
5mg prednisone is working now, body feels like it has adapted to the lower dose
Aches and pains are much subdued. I do think I can keep lowering, but I am a little worried about my hands now. As in maybe the small amount of prednisone is helping down the inflammation there. I have had carpel tunnel symptoms for at least 10 years. Now I know I have some OA in the hands from the xrays
Aches and pains are much subdued. I do think I can keep lowering, but I am a little worried about my hands now. As in maybe the small amount of prednisone is helping down the inflammation there. I have had carpel tunnel symptoms for at least 10 years. Now I know I have some OA in the hands from the xrays
sdowney717
in
PMRGCAuk
1 year ago
A1C level
I called my doctor's office ahead of my Monday appointment to ask what my A1C was. It went from 7.7 to 7.3. I am disappointed that it wasn't lower with the amount of insulin I take. I know I can be better with my diet and exercise. I have been alot better using my CPAP. Disappointed was hoping for
I called my doctor's office ahead of my Monday appointment to ask what my A1C was. It went from 7.7 to 7.3. I am disappointed that it wasn't lower with the amount of insulin I take. I know I can be better with my diet and exercise. I have been alot better using my CPAP. Disappointed was hoping for
Trainchaser
in
Major Depressive Disorder (MDD) Support
1 year ago
Insulin working differently after cabg
Hi I've had a cabg x4. Before surgery my diabetes was stable using both a slow release and a fast acting insulin. Since the operation the insulin is reacting more strongly to the same foods & I can't seem get a balance without dropping - and whichever medics I ask they have no knowledge of this. I
Hi I've had a cabg x4. Before surgery my diabetes was stable using both a slow release and a fast acting insulin. Since the operation the insulin is reacting more strongly to the same foods & I can't seem get a balance without dropping - and whichever medics I ask they have no knowledge of this. I
CabgInsulin
in
British Heart Foundation
1 year ago
par36
I'm diabetic and have heart failure (stent fitted) , I take tablets for blood pressure and cholesterol , insulin and tablets for diabetes, my main problem is getting up in the mornings I feel as if I've been hit by a bus I'm so sore I can hardly get out of bed , my back and legs are so sore , and
I'm diabetic and have heart failure (stent fitted) , I take tablets for blood pressure and cholesterol , insulin and tablets for diabetes, my main problem is getting up in the mornings I feel as if I've been hit by a bus I'm so sore I can hardly get out of bed , my back and legs are so sore , and
9iron
in
British Heart Foundation
1 year ago
statins
I’m type 1 diabetic, my whole cholesterol was 4.6 and my bad cholesterol was 3.0 Tried two statins didn’t agree with me, now went to lipid clinic, was put on Rosuvastatin which agrees with me, the only problem is my sugar levels go skyrocketing for a good few hours after i take it. This is concerning
I’m type 1 diabetic, my whole cholesterol was 4.6 and my bad cholesterol was 3.0 Tried two statins didn’t agree with me, now went to lipid clinic, was put on Rosuvastatin which agrees with me, the only problem is my sugar levels go skyrocketing for a good few hours after i take it. This is concerning
Yellow26
in
British Heart Foundation
1 year ago
Another question for the diabetics here that are on insulin.
I've just been put on insulin. I take it before each meal and then a long lasting one before bed. My question is, how do you manage when going out to eat? Do you inject at restaurant? Skip a dose or before or after you get home. Not asking for medical opinions just how do you manage this? It would
I've just been put on insulin. I take it before each meal and then a long lasting one before bed. My question is, how do you manage when going out to eat? Do you inject at restaurant? Skip a dose or before or after you get home. Not asking for medical opinions just how do you manage this? It would
jodaer
in
Kidney Disease
1 year ago
Insulin Dosages
Hi, I'm Eccleston and have been treated as a T2 for a number of years now. I quickly progressed to the need for insulin and have concerns that the level of insulin being injected may be well above the average. Is there anyone who would be willing to share their experience please? Current insulin treatment
Hi, I'm Eccleston and have been treated as a T2 for a number of years now. I quickly progressed to the need for insulin and have concerns that the level of insulin being injected may be well above the average. Is there anyone who would be willing to share their experience please? Current insulin treatment
Eccleston
in
Diabetes Support
1 year ago
Been doing great lately, reduced again from 10 to 7.5mg prednisone. My crp is under 10 from 103
I had seen the rheumatologist and had dropped from 12.5 to 10, after the visit. Now for last 2 days I am down to 7.5mg prednisone, my own decision, I am certain he wont mind.... It still feels a little ragged in the AM, but I recover well and feel good all the rest of the day after a few hours. Still
I had seen the rheumatologist and had dropped from 12.5 to 10, after the visit. Now for last 2 days I am down to 7.5mg prednisone, my own decision, I am certain he wont mind.... It still feels a little ragged in the AM, but I recover well and feel good all the rest of the day after a few hours. Still
sdowney717
in
PMRGCAuk
1 year ago
Do you have experince of taking 'Cipro' (ciprofloxacin)?
Hi friends I have a [i]pseudomonas[/i] infection making me feel very unwell. My specialist wants me to take 'Cipro' (ciprofloxacin) tablets. The side-effects sound frightening - especially for a 72 year old. Can you tell me your experiences of taking this medication. The dose my specialist recommnds
Hi friends I have a [i]pseudomonas[/i] infection making me feel very unwell. My specialist wants me to take 'Cipro' (ciprofloxacin) tablets. The side-effects sound frightening - especially for a 72 year old. Can you tell me your experiences of taking this medication. The dose my specialist recommnds
Ozzie3
in
Bronchiectasis Support
1 year ago
Hight TSH and High LDL cholesterol connection
Hello my latest blood test shown High TSH (6.36), and high LDL cholesterol (6), I had full blood test done in May and my TSH was very low (0.26)that s why doctor lowered my eltroxin from 200mg down to 175mg, retest was done three months later, now my ldl cholesterol is going up again even though i follow
Hello my latest blood test shown High TSH (6.36), and high LDL cholesterol (6), I had full blood test done in May and my TSH was very low (0.26)that s why doctor lowered my eltroxin from 200mg down to 175mg, retest was done three months later, now my ldl cholesterol is going up again even though i follow
deni78
in
Thyroid UK
1 year ago
miscarriage advise needed
Hi all! So we used donor sperm and have had two FET’s so far both ended in miscarriage(first at 7th week and second was chemical)! Can this be normal and still carry a baby to term? We are same sex couple so I’ve never tried to conceive before, so no known fertility issues and all tests (bloods,
Hi all! So we used donor sperm and have had two FET’s so far both ended in miscarriage(first at 7th week and second was chemical)! Can this be normal and still carry a baby to term? We are same sex couple so I’ve never tried to conceive before, so no known fertility issues and all tests (bloods,
Hidden
in
Fertility Network UK
1 year ago
forteo terrosa pen
there are few if any videos on administrating a dose of forteo. what's the volume of a single dose? are all the doses stored within the pen? it's it similar to insulin injecting?, because Mum will need to be shown m surely the nurses at the GP's will be able to do demonstrate and do the first shot
there are few if any videos on administrating a dose of forteo. what's the volume of a single dose? are all the doses stored within the pen? it's it similar to insulin injecting?, because Mum will need to be shown m surely the nurses at the GP's will be able to do demonstrate and do the first shot
MayGodBlessYou
in
Bone Health and Osteoporosis UK
1 year ago
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