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Hydrochlorothiazide and olmesartan
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Bleeding when opening the bowels
does anyone else get this? I had to have an emergency appointment today as I went to the toilet and when I opened my bowels and looked in the toilet, the water and bowl were full of blood! I had confirmed stage 2 endo on my bladder and ovary, I’ve also had mumtiple colonoscopies, sigmoidoscopies, endoscopies
does anyone else get this? I had to have an emergency appointment today as I went to the toilet and when I opened my bowels and looked in the toilet, the water and bowl were full of blood! I had confirmed stage 2 endo on my bladder and ovary, I’ve also had mumtiple colonoscopies, sigmoidoscopies, endoscopies
nikogirl18
in
Endometriosis UK
7 months ago
biopsy - fragmented cores and progression risk
I had 3 biopsies from January 2020 to July 2022. The first two almost identical being Gleason 3+4 with <10% 4. However 6 months post HIFU it was Gleason 9 with 4+5 with 10% 5 and 70% 5 (see below). I am curious as the cores are fragmented and so it’s hard to know what this means and if it makes any
I had 3 biopsies from January 2020 to July 2022. The first two almost identical being Gleason 3+4 with <10% 4. However 6 months post HIFU it was Gleason 9 with 4+5 with 10% 5 and 70% 5 (see below). I am curious as the cores are fragmented and so it’s hard to know what this means and if it makes any
SimMartin
in
Advanced Prostate Cancer
7 months ago
Ketogenic diet alters the epigenetic and immune landscape of prostate cancer to overcome resistance to immune checkpoint blockade therapy.
Overall, this strikes me as too hypothetical for us to apply, but what do I know? "Overall, these findings illuminate a potential clinical path of using HDACi and optimized KD regimens to enhance ICB therapy for PCa." HDACi = histone deacetylase inhibitor [To date, four HDAC inhibitors, Vorinostat
Overall, this strikes me as too hypothetical for us to apply, but what do I know? "Overall, these findings illuminate a potential clinical path of using HDACi and optimized KD regimens to enhance ICB therapy for PCa." HDACi = histone deacetylase inhibitor [To date, four HDAC inhibitors, Vorinostat
cigafred
in
Fight Prostate Cancer
4 months ago
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breathing and health anxiety
Hi all. Much like yourselves it’s a long dotted history with IBS. I’m back dealing with a bout following a stomach bug and work stress. My whole system locked up and slowly became almost unbearable. This time it’s feeling as if my breathing is being placed under pressure as I’m so bloated. The odd times
Hi all. Much like yourselves it’s a long dotted history with IBS. I’m back dealing with a bout following a stomach bug and work stress. My whole system locked up and slowly became almost unbearable. This time it’s feeling as if my breathing is being placed under pressure as I’m so bloated. The odd times
Loftytopping
in
IBS Network
4 months ago
is this cancer?
i’ve posted on here once for a scare, i’m back again. i’m 24 years old, and my poop has just not been super normal since i have had the thought it could be colon cancer. i have a spot on my lower left abdominal area, right below belly button, i assumed it to be a hernia. my doctor sent me for an ultrasound
i’ve posted on here once for a scare, i’m back again. i’m 24 years old, and my poop has just not been super normal since i have had the thought it could be colon cancer. i have a spot on my lower left abdominal area, right below belly button, i assumed it to be a hernia. my doctor sent me for an ultrasound
imscaredofcancer
in
Colon Cancer Connected
4 months ago
New diagnosis
I was just diagnosed with fibromyalgia. Four years ago, I was diagnosed with Giant Cell Arteritis and, about 2 years later, Polymyalgia Rheumatica. My life has drastically changed between the pain and total exhaustion. Any words of advice would be most welcome.
I was just diagnosed with fibromyalgia. Four years ago, I was diagnosed with Giant Cell Arteritis and, about 2 years later, Polymyalgia Rheumatica. My life has drastically changed between the pain and total exhaustion. Any words of advice would be most welcome.
Miacaro45
in
Fibromyalgia Action UK
4 months ago
Update
I’m now down to 15mg and my stomach is still swollen but cause seems to be Serositis. My pleural effusion are 200/300mls left side and zero right side with now minimal around pericardial so steroids are definitely working indicating cause is definitely autoimmune and possibly PMR . I still don’t feel
I’m now down to 15mg and my stomach is still swollen but cause seems to be Serositis. My pleural effusion are 200/300mls left side and zero right side with now minimal around pericardial so steroids are definitely working indicating cause is definitely autoimmune and possibly PMR . I still don’t feel
Numptybrain
in
PMRGCAuk
4 months ago
Hello friends. It's me again. Bone Biopsy + Dr. nonsense.
Ok, so I have not posted my situation for awhile because I was/am still waiting for tests. Quick review-Luminal A Hr Es+ 90-100% Pr+80-90%,ki67<10% HER2 neg(2+,sish neg) her2 low, I guess. This was the original in 2016. Had chemo, rads, anastrozle up to 2019 when dx mbc. Ibrance + fasoldex, then xeloda
Ok, so I have not posted my situation for awhile because I was/am still waiting for tests. Quick review-Luminal A Hr Es+ 90-100% Pr+80-90%,ki67<10% HER2 neg(2+,sish neg) her2 low, I guess. This was the original in 2016. Had chemo, rads, anastrozle up to 2019 when dx mbc. Ibrance + fasoldex, then xeloda
Hopeful4Cure
in
SHARE Metastatic Breast Cancer
7 months ago
Please send me some positivity.
I have just had the results of my CT scan and I have been told I have a recurrance in one para-aortic lymph node. I will either need surgery (if they can), chemo or radiotherapy. I'm so scared as this is my first recurrence from Stage 4 ovarian cancer and I'm only 56 and have two teenagers. I can't
I have just had the results of my CT scan and I have been told I have a recurrance in one para-aortic lymph node. I will either need surgery (if they can), chemo or radiotherapy. I'm so scared as this is my first recurrence from Stage 4 ovarian cancer and I'm only 56 and have two teenagers. I can't
Nectirlawone
in
My Ovacome
7 months ago
And more ASCO GU 2024 phase 3 trial
Data will be presented at ASCO GU 2024 but looks promising "In combination with immunotherapy, Cabometyx is delivering long-term survival benefits today for people living with renal cell carcinoma worldwide, while also showcasing future potential in metastatic castration-resistant prostate cancer, an
Data will be presented at ASCO GU 2024 but looks promising "In combination with immunotherapy, Cabometyx is delivering long-term survival benefits today for people living with renal cell carcinoma worldwide, while also showcasing future potential in metastatic castration-resistant prostate cancer, an
Maxone73
in
Advanced Prostate Cancer
7 months ago
Abnormalities on the CT 6 months after Chemo (while on Niraparib) CA125 at 4.9, anyone same experience?
Dear ladies, Background : IVB HSOC Jan 2023, Debulking April 23, last chemo June 23, on Niraparib since Aug 23, diagnosed at 40 yo (now 41). Now CT shows small abnormalities: They saw 2 nodular abnormalities on CT scan, (16mm) suspecting local recurrence but they do not know for sure. Also they noticed
Dear ladies, Background : IVB HSOC Jan 2023, Debulking April 23, last chemo June 23, on Niraparib since Aug 23, diagnosed at 40 yo (now 41). Now CT shows small abnormalities: They saw 2 nodular abnormalities on CT scan, (16mm) suspecting local recurrence but they do not know for sure. Also they noticed
Beatyourself
in
My Ovacome
7 months ago
unknown face rash
hi— My five-year-old son has had a rash on his face for over a month now. The rash initially started on his ear but resolved,, however the face stayed the same. We’ve taken him to his pediatrician emergency room and dermatologist and nobody knows what it is. Right after the spots started to appear he
hi— My five-year-old son has had a rash on his face for over a month now. The rash initially started on his ear but resolved,, however the face stayed the same. We’ve taken him to his pediatrician emergency room and dermatologist and nobody knows what it is. Right after the spots started to appear he
Demaso33
in
LUPUS UK
3 months ago
Surgery vs SBRT Cyberknife
Hubs diagnosed 11/15/23. 2 of 12 positive. Gleason 6 and 7. PSA 3.7-4.2. Met with Surgeon first, "slow growing, non aggressive" he believes is contained by looking at margins and pathology. Met with Radiology Oncologist, "favorable intermediate risk, non aggressive" he believes it is contained. Both
Hubs diagnosed 11/15/23. 2 of 12 positive. Gleason 6 and 7. PSA 3.7-4.2. Met with Surgeon first, "slow growing, non aggressive" he believes is contained by looking at margins and pathology. Met with Radiology Oncologist, "favorable intermediate risk, non aggressive" he believes it is contained. Both
Pride123
in
Advanced Prostate Cancer
7 months ago
Polyneuropathy.
I treat my polyneuropathy with B6 and B12. GracePV shared their experience with B6, B12 nd B1. This inspired me to revisit my self treatment of my polyneuropathy. I came across information about Benfotiamine which is similar to Thiamine Hydrochloride and Thiamine Nitrate. There are indications
I treat my polyneuropathy with B6 and B12. GracePV shared their experience with B6, B12 nd B1. This inspired me to revisit my self treatment of my polyneuropathy. I came across information about Benfotiamine which is similar to Thiamine Hydrochloride and Thiamine Nitrate. There are indications
WIZARD6787
in
Pernicious Anaemia Society
4 months ago
"Gut Dysbiosis in Irritable Bowel Syndrome: A Narrative Review on Correlation with Disease Subtypes and Novel Therapeutic Implications"
Research. Source: https://www.mdpi.com/2076-2607/11/10/2369
Abstract
"Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder characterized by chronic abdominal pain and altered bowel habits. It can be subclassified in different subtypes according to the main clinical
Research. Source: https://www.mdpi.com/2076-2607/11/10/2369
Abstract
"Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder characterized by chronic abdominal pain and altered bowel habits. It can be subclassified in different subtypes according to the main clinical
Meleber
in
IBS Network
4 months ago
scabies won´t go away, help
Hello, have anybody scabies won´t go away? I have it for 2 years now and it is horrobil. I try everything (all chemicals / medicine, all natural things with vaseline and sulfur and with all ethereal oils, with enzyme, with borax, CDL, bleech and so on outside , mixed it in all ways. and inside with
Hello, have anybody scabies won´t go away? I have it for 2 years now and it is horrobil. I try everything (all chemicals / medicine, all natural things with vaseline and sulfur and with all ethereal oils, with enzyme, with borax, CDL, bleech and so on outside , mixed it in all ways. and inside with
Massio
in
BASHH
4 months ago
Vitamin D dropped again
Hi everyone I had my Vitamin tested in January and I was deficient. January 2024: Vitamin D deficient (Vitamin D: 27.4 ng/ml (Low) ….(30-100) I decided to sit outside instead of supplement (weather has been very mild) I just got my results for April 2024 and Im worse off… April 2024: Vitamin
Hi everyone I had my Vitamin tested in January and I was deficient. January 2024: Vitamin D deficient (Vitamin D: 27.4 ng/ml (Low) ….(30-100) I decided to sit outside instead of supplement (weather has been very mild) I just got my results for April 2024 and Im worse off… April 2024: Vitamin
Batty1
in
Thyroid UK
4 months ago
Betaine HCL
Good day Friends. I am considering trying Betaine, I have Autoimmune Gastritis. Have been having what I think is gas pain, it can be in left chest, upper right quadrant, right chest area, it moves around. Sometimes sits just before lower chest area. Sometimes its s stabbing pain in chest/abdomen
Good day Friends. I am considering trying Betaine, I have Autoimmune Gastritis. Have been having what I think is gas pain, it can be in left chest, upper right quadrant, right chest area, it moves around. Sometimes sits just before lower chest area. Sometimes its s stabbing pain in chest/abdomen
Canadian77
in
Pernicious Anaemia Society
4 months ago
clinical trial: ATR inhibitor for ATM mutated solid tumors
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
Maxone73
in
Advanced Prostate Cancer
7 months ago
Orchidectomy vs ADT
For anyone who had the bilateral orchidectomy, I would like some advice for my husband. When was it done? Before or after BCR occurred? What are the side effects? Do you take any other ADT meds after? How is your QOL and is there anything you'd do differently. He had RP in Dec 2021. No other treatment
For anyone who had the bilateral orchidectomy, I would like some advice for my husband. When was it done? Before or after BCR occurred? What are the side effects? Do you take any other ADT meds after? How is your QOL and is there anything you'd do differently. He had RP in Dec 2021. No other treatment
tn12
in
Advanced Prostate Cancer
7 months ago
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