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Know your Biomarker … Know Your Mutation
KRAS mutation in colorectal cancer is an abnormal change in the KRAS gene, which is involved in controlling cell growth and survival. 40% of CRC has a KRAS mutation. There are more than 25 ongoing clinical trials studying treatments for KRAS-mutated colorectal cancer. Learn more about the KRAS biomarker
KRAS mutation in colorectal cancer is an abnormal change in the KRAS gene, which is involved in controlling cell growth and survival. 40% of CRC has a KRAS mutation. There are more than 25 ongoing clinical trials studying treatments for KRAS-mutated colorectal cancer. Learn more about the KRAS biomarker
GCCA-Survivor
Administrator
in
Colon Cancer Connected
8 months ago
Staying on Ibrance & Anastrozole after 2 recurrences
I’ve been on Ibrance and Anastrozole for the last 6 years for metastatic endometrial cancer. I started out on the Ibrance125 mg and after a couple of years, had a problem recovering on the week off, so my dose was reduced to 100 mg. By spring this year, the counts could not recover on the week off,
I’ve been on Ibrance and Anastrozole for the last 6 years for metastatic endometrial cancer. I started out on the Ibrance125 mg and after a couple of years, had a problem recovering on the week off, so my dose was reduced to 100 mg. By spring this year, the counts could not recover on the week off,
Merma
in
SHARE Metastatic Breast Cancer
8 months ago
flare up
hi I’ve had diahorria and left side pain and mild nausea for a few days now . Keep thinking it’s better and it’s not ! Self employed but in clients houses so keep cancelling the ones that are home! Now got some appointments coming up some where no loo and feel I need to cancel , Is this a “flare up
hi I’ve had diahorria and left side pain and mild nausea for a few days now . Keep thinking it’s better and it’s not ! Self employed but in clients houses so keep cancelling the ones that are home! Now got some appointments coming up some where no loo and feel I need to cancel , Is this a “flare up
Purplewoman
in
IBS Network
6 months ago
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lactose intolerant
i can’t find any chat for this problem when searching so chose this site. i’m lactose intolerant but it doesn’t bother me much. only thing i avoid is normal milk. i have lactose free milk but yesterday finished and i’ve been having normal. i’ve noticed stomach ache bloating. can this be caused by this
i can’t find any chat for this problem when searching so chose this site. i’m lactose intolerant but it doesn’t bother me much. only thing i avoid is normal milk. i have lactose free milk but yesterday finished and i’ve been having normal. i’ve noticed stomach ache bloating. can this be caused by this
Junny123
in
Pain Concern
6 months ago
How fast is brain iron deficiency restored after IV iron?
Hello everyone.In January I got transcranial sonography done and they found brain iron deficiency. I had ferritin at 150, TS at 30% so they gave me 500mg ferric carboxymaltose. We are planning to repeat it. My question is, those who had BID diagnosed, after how many infusions did RLS pain go away? Did
Hello everyone.In January I got transcranial sonography done and they found brain iron deficiency. I had ferritin at 150, TS at 30% so they gave me 500mg ferric carboxymaltose. We are planning to repeat it. My question is, those who had BID diagnosed, after how many infusions did RLS pain go away? Did
vikkkk
in
Restless Legs Syndrome
6 months ago
Squamous cell Carcinoma
HERE’S WHAT TO LOOK OUT FOR: Small, hard white or skin coloured lumps. SCCs often first appear on the skin like this. A persistent, scaly red patch with irregular borders. These can sometimes crust or bleed. An elevated growth with a central depression A growth of this type may rapidly increase
HERE’S WHAT TO LOOK OUT FOR: Small, hard white or skin coloured lumps. SCCs often first appear on the skin like this. A persistent, scaly red patch with irregular borders. These can sometimes crust or bleed. An elevated growth with a central depression A growth of this type may rapidly increase
SkcinHQ
Partner
in
Skin Cancer UK
8 months ago
Does anyone have this IBS’s symptoms ?
3 moths age and daily I wake up with severe pain in my stomach like I feel very hungry . My endoscopy was negative of any thing . My question does anyone suffer from this symptoms who has IBS please ? Thank you.
3 moths age and daily I wake up with severe pain in my stomach like I feel very hungry . My endoscopy was negative of any thing . My question does anyone suffer from this symptoms who has IBS please ? Thank you.
Raneena
in
IBS Network
6 months ago
Orchiectomy and Psa
Can anyone who has had Bilateral Ochiectomy tell me if there is a certain psa level required before surgery can be done. Thanks Guys Knittingque
Can anyone who has had Bilateral Ochiectomy tell me if there is a certain psa level required before surgery can be done. Thanks Guys Knittingque
Knittingque
in
Advanced Prostate Cancer
8 months ago
long term omeprazole use
I was taking omeprazole for about 15 years and stopped in December last year, as I had done some research and found out it can affect stomach acid. No one told me to stop taking it. I don’t even know why I was put on it in the first place, up I think it was for IBS. I haven’t had any acid reflux or indigestion
I was taking omeprazole for about 15 years and stopped in December last year, as I had done some research and found out it can affect stomach acid. No one told me to stop taking it. I don’t even know why I was put on it in the first place, up I think it was for IBS. I haven’t had any acid reflux or indigestion
Chickens44
in
Pernicious Anaemia Society
6 months ago
Need Help For My GP…
I am having an ongoing discussion with my GP about giving me the dose I need for my deficiency (EOD). It has been mainly positive so far, during my appointment yesterday he did acknowledge that he knew little about this malady, he would also need to chat to his partners and get advice from a specialist
I am having an ongoing discussion with my GP about giving me the dose I need for my deficiency (EOD). It has been mainly positive so far, during my appointment yesterday he did acknowledge that he knew little about this malady, he would also need to chat to his partners and get advice from a specialist
B12again
in
Pernicious Anaemia Society
6 months ago
carbo/gem
I was diagnosed high grade stage 3c peritoneal in Autumn 2021, I have had carbo/taxol/avastin, debulking surgery. Followed by avastin alone which did not work, then carbo/caelyx which worked very well. I have had just over a year on Niraparib but sadly it is no longer working. I am due to start
I was diagnosed high grade stage 3c peritoneal in Autumn 2021, I have had carbo/taxol/avastin, debulking surgery. Followed by avastin alone which did not work, then carbo/caelyx which worked very well. I have had just over a year on Niraparib but sadly it is no longer working. I am due to start
NewtonEmma1900
in
My Ovacome
6 months ago
Has anyone tried pulsed electric magnetic field therapy for PMR relief?
I am having trouble tapering. Can't seem to get much below 15 mg; went down to 10 mg but still having some pain in the mornings. So increased dosage on advice of rheumy. At this rate, I'll be on prednisone for a long, long time. So wondering if anyone has tried alternative treatments to try to get
I am having trouble tapering. Can't seem to get much below 15 mg; went down to 10 mg but still having some pain in the mornings. So increased dosage on advice of rheumy. At this rate, I'll be on prednisone for a long, long time. So wondering if anyone has tried alternative treatments to try to get
lsplumb
in
PMRGCAuk
6 months ago
Daridexorant / quvuviq and RLS
Just wondering if anyone else has experience of this sleep aid and RLS? I have bought (not available in my region on NHS yet) a month’s supply of 50mg tablets and ….. I am sleeping normally!!!! It is a new drug to the UK but tried and tested in USA I believe? Apparently minimal side effects. I have
Just wondering if anyone else has experience of this sleep aid and RLS? I have bought (not available in my region on NHS yet) a month’s supply of 50mg tablets and ….. I am sleeping normally!!!! It is a new drug to the UK but tried and tested in USA I believe? Apparently minimal side effects. I have
Lacey_
in
Restless Legs Syndrome
5 months ago
serotonin syndrome
I have a mild case of serotin syndrome… done stuff I shouldn’t have but anxiety and depression is creeping back up on me…. The issue is I’m not sure if I’m really disappointed in people or if the syndrome talking … there times where it just easier to get lost in my made up reality then live in funk
I have a mild case of serotin syndrome… done stuff I shouldn’t have but anxiety and depression is creeping back up on me…. The issue is I’m not sure if I’m really disappointed in people or if the syndrome talking … there times where it just easier to get lost in my made up reality then live in funk
CorgiPower
in
Anxiety and Depression Support
3 months ago
liver Mets, Pluvicto failed
diagnosed 2021, spread to distant lymph nodes. Castrate resistant within 6 months. Had platinum based chemo. Stabilized for bit. 4 Pluvicto treatments. PSA went from 4 to 70. Latest scans show new mets to liver. Genetic testing shows ATM mutation. Where to go from here?
diagnosed 2021, spread to distant lymph nodes. Castrate resistant within 6 months. Had platinum based chemo. Stabilized for bit. 4 Pluvicto treatments. PSA went from 4 to 70. Latest scans show new mets to liver. Genetic testing shows ATM mutation. Where to go from here?
mysticmini
in
Advanced Prostate Cancer
8 months ago
Help I don’t understand
So for the last 4 months I’ve been having pain in my muscles and head as well as tingling and a burning sensation. Also extreme fatigue and a red rash on my cheeks and trouble swallowing.My doctor gave me prednisone to treat because crp and esr were high. She also started me on plaquenil. Now before
So for the last 4 months I’ve been having pain in my muscles and head as well as tingling and a burning sensation. Also extreme fatigue and a red rash on my cheeks and trouble swallowing.My doctor gave me prednisone to treat because crp and esr were high. She also started me on plaquenil. Now before
Jadaboo4
in
LUPUS UK
5 months ago
Brain Lipoma Symptoms
Hi, I'm looking for others who have this rare type of benign brain tumour. What are some of your symptoms and what has been your journey in getting help. I have a lipoma in the middle of my brain and have headaches, limb weakness and some other issues but can't find anyone to relate to..... thank you
Hi, I'm looking for others who have this rare type of benign brain tumour. What are some of your symptoms and what has been your journey in getting help. I have a lipoma in the middle of my brain and have headaches, limb weakness and some other issues but can't find anyone to relate to..... thank you
Flower589
in
Headway
8 months ago
virtual appointment
Hi, I’m hoping and would be grateful for any advice from this knowledgeable group.. I’m due to have a virtual 6 monthly review tomorrow following blood tests and US. I have been diagnosed with cryptogenic cirrhosis with no known cause. This was following a fibroscan result of 17kpa. When I had the
Hi, I’m hoping and would be grateful for any advice from this knowledgeable group.. I’m due to have a virtual 6 monthly review tomorrow following blood tests and US. I have been diagnosed with cryptogenic cirrhosis with no known cause. This was following a fibroscan result of 17kpa. When I had the
0range5520
in
British Liver Trust
6 months ago
Heliocare
I am going to post this and everyone can do with the information what they want. I wanted to bring this dietary supplement to everyone’s attention especially those of us who take meds that put us at higher risks for skin cancer from our meds. Heliocare is a dietary supplement I have kept seen coming
I am going to post this and everyone can do with the information what they want. I wanted to bring this dietary supplement to everyone’s attention especially those of us who take meds that put us at higher risks for skin cancer from our meds. Heliocare is a dietary supplement I have kept seen coming
KLCTJC
in
MPN Voice
8 months ago
Iron and ferritin advice requested
I have recently had a full set of iron and ferritin blood tests completed and would like some advice on the numbers, please (prior to these tests, only my ferritin levels have been tested). They result from early morning fasting with no iron supplements for one week. My serum ferritin was 160 µg/L.
I have recently had a full set of iron and ferritin blood tests completed and would like some advice on the numbers, please (prior to these tests, only my ferritin levels have been tested). They result from early morning fasting with no iron supplements for one week. My serum ferritin was 160 µg/L.
MrVimes
in
Restless Legs Syndrome
6 months ago
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