carbo/gem

[NewtonEmma1900]

I was diagnosed high grade stage 3c peritoneal in Autumn 2021, I have had carbo/taxol/avastin, debulking surgery. Followed by avastin alone which did not work, then carbo/caelyx which worked very well. I have had just over a year on Niraparib but sadly it is no longer working. I am due to start carbo/gem in a few weeks. Any advice or information on this treatment would be welcome?

Katy 🙏

[Caleda4]

Hi, I had this combination in 2020. You normally have first dose carbo/gem then 8 days later gem only, followed by 2 weeks off. Like all chemo it can knock the neutrophils, and bone marrow, I was lucky as did not have that problem. I am due to start this regime again this month. This will be 4th line chemo for me. I had carbo/ caelyx in 2022. I wish you well.

[NewtonEmma1900 in reply to Caleda4]

Thank you Caleda, it’s the part when we are waiting for them to schedule the appointment dates that I find really difficult! I was ok on carbo/caelyx so fingers crossed that I will be lucky. Sending best wishes for your treatment too. 🙏💐

[Cheka123 in reply to NewtonEmma1900]

i have diagnosed the same ..just on round 4 chemo recurrence some what in the dark of my condition...tho..blood test so far are good tumour markers coming down..but i do have a nagging situation abvove my belly button the dex pills i take sure kick me around few days after the chemo treatments..i wish you the best as we all do..got a ct scan hope it positive also

[NewtonEmma1900 in reply to Cheka123]

Wishing you well too. 🙏❤️

[Green999 in reply to Caleda4]

Hi,

I will started second line with carboplatin , gem and Avastin. I am wondering if I will lose my hair again?

[Caleda4 in reply to Green999]

When I had carbo/gem in 2020 my hair only thinned and it was not noticeable, so I hope that you will be ok.

[Helvelyn]

Hi Katy

I have just started this for my 1st reoccurrence.

I have only had round one so far and due to start round 2 tomorrow.

So far it’s been ok but have been quite fatigued and also experiencing stomach pains but that might be tumour related.

I think the main issue is that it does attack your bone marrow so my platelets have dropped but they keep a very close eye on you.

I hope you tolerate it well.

lots of love

Julie xx

[NewtonEmma1900 in reply to Helvelyn]

Thank you very much, as ever with OC I guess I should prepare for the worst but hope for the best. 🙏

[Leniko in reply to Helvelyn]

I also had stomach pain and major fatigue!

[Alice77]

Hi. Our journeys are not dissimilar. I was also diagnosed HG PPC 3C in 2021 and have had 8 cycles of Paclitaxel and Carboplatin, ultra radical cytoreduction surgery, Niraparib which worked for about a year and more recently Carbo Caelyx which was working well until I became Carbo resistant after three cycles and the cancer then progressed during the chemo with Caelyx alone. My options are now limited but I have been trying to get more treatment with weekly Paclitaxel and am awaiting another CT scan and blood test. There are concerns because of the neuropathy and allergies I developed when I last had this drug. I am 73 and they are worried about me but I am concerned that the other option seems to be no effective treatment at all unless I am accepted for a trial. I am interested to see how you get on with the Gemcitabine, although I can't have the Carbo with it. My thoughts and very best wishes are with you and I hope all goes well.

[NewtonEmma1900 in reply to Alice77]

We are similar! I even have an umbilical hernia. Neuropathy was awful and losing my hair too on Paclitaxel so I do understand your worries. Sending best wishes and keep us posted. Katy🙏

[Leniko]

I know that friends that have taken this combo have done very well! 🙏