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Which Estrogen Patch dose to use?
This plot shows the median serum estrogen (E2) concentration (in pg/mL) versus total Weekly Estrogen patch dose (mg/wk) from five different references ranging from 2000 to 2019. The data set from Smith et. al (2019) is for castrate-resistant prostate cancer men (CRPC), who are not taking ADT. Overall
This plot shows the median serum estrogen (E2) concentration (in pg/mL) versus total Weekly Estrogen patch dose (mg/wk) from five different references ranging from 2000 to 2019. The data set from Smith et. al (2019) is for castrate-resistant prostate cancer men (CRPC), who are not taking ADT. Overall
janebob99
in
Prostate Cancer Network
4 months ago
Advice on hormonal treatment?
hi all, 10 days post-lap here. Unfortunately ended up losing my left ovary and tube - had 4 endometriomas on it, 1 of which was 8cm, and this was all adhered to my rectum. So the surgeon said it needed to come out. I’m waiting for a post-op appointment but the consultant said the endo will likely come
hi all, 10 days post-lap here. Unfortunately ended up losing my left ovary and tube - had 4 endometriomas on it, 1 of which was 8cm, and this was all adhered to my rectum. So the surgeon said it needed to come out. I’m waiting for a post-op appointment but the consultant said the endo will likely come
Apprentice_Hag
in
Endometriosis UK
4 months ago
Newbie - Is this Normal? Should I have Treatment?
Good morning! I'm a newbie here and i'm just unsure as to whether I should accept what my GP is telling me and put up with it or go private. A bit of history - I'm 46, female, overall good health historically but diagnosed with Premature Ovarian Deficiency (Early menopause) in my early thirties.
Good morning! I'm a newbie here and i'm just unsure as to whether I should accept what my GP is telling me and put up with it or go private. A bit of history - I'm 46, female, overall good health historically but diagnosed with Premature Ovarian Deficiency (Early menopause) in my early thirties.
Ruthio77
in
Thyroid UK
4 months ago
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Question in Preparation for pBAT
For those who have experience with BAT: I’m getting ready to start my first 30 day cycle of pBAT this week. But I have a concern about my high SHBG (sex hormone binding globulin) level, which is 79 nmol/L. With Eligard ADT in the background, my pBAT program calls for 8 injections of T propionate
For those who have experience with BAT: I’m getting ready to start my first 30 day cycle of pBAT this week. But I have a concern about my high SHBG (sex hormone binding globulin) level, which is 79 nmol/L. With Eligard ADT in the background, my pBAT program calls for 8 injections of T propionate
Ichthus316
in
Fight Prostate Cancer
4 months ago
Similar question to Ezzedine. PSA rising
March 19 I was diagnosed with Gleason 9 prostate cancer. PSA was 0.9 (it turns out I have a non secreting prostate. I had 37 sessions of EBRT and 3 years zoladex. Whilst under ADT and for 1 year after ADT conclusion my PSA was 0.01 (indecipherable) Then a year ago my PSA was 0.02, then 0.03 and last
March 19 I was diagnosed with Gleason 9 prostate cancer. PSA was 0.9 (it turns out I have a non secreting prostate. I had 37 sessions of EBRT and 3 years zoladex. Whilst under ADT and for 1 year after ADT conclusion my PSA was 0.01 (indecipherable) Then a year ago my PSA was 0.02, then 0.03 and last
arry4424
in
Prostate Cancer Network
4 months ago
Very confused and don't know what to do to help my body heal
Hi everyone, I'm new to this forum and up to 6 weeks ago the only digestive concerns I had was Coeliac Disease and a sliding hiatal hernia which was discovered at my endoscopy 4 years ago. The hernia hasn't given me any bother up to this point except for the occasional bout of acid reflux every couple
Hi everyone, I'm new to this forum and up to 6 weeks ago the only digestive concerns I had was Coeliac Disease and a sliding hiatal hernia which was discovered at my endoscopy 4 years ago. The hernia hasn't given me any bother up to this point except for the occasional bout of acid reflux every couple
Sparkstar2
in
Acid Reflux Support
4 months ago
Constant uti's
Hello everyone Hope you are all as well as you can be . I think I just need a space to talk where people understand and offer valuable advice. I was diognosed with sle lupus and sjogrens in Dec 22 and was put on hydroxychloroquine plus drops /ointments for eyes artificial saliva ect ect. Since then
Hello everyone Hope you are all as well as you can be . I think I just need a space to talk where people understand and offer valuable advice. I was diognosed with sle lupus and sjogrens in Dec 22 and was put on hydroxychloroquine plus drops /ointments for eyes artificial saliva ect ect. Since then
Lucylou72
in
LUPUS UK
7 months ago
RT with ADT Relogolix (Orgovyx) vs Enzalutamide (Xtandi) Side Effect Differences?
There may not be a lot of people that can offer anecdotal reports on both as monotherapies but the reason I ask is some studies in the last 3 years are showing administration of Xtandi during Radiotherapy has shown outcomes as good as if not better than RT + ADT. https://www.sciencedirect.com/science
There may not be a lot of people that can offer anecdotal reports on both as monotherapies but the reason I ask is some studies in the last 3 years are showing administration of Xtandi during Radiotherapy has shown outcomes as good as if not better than RT + ADT. https://www.sciencedirect.com/science
jazj
in
Advanced Prostate Cancer
4 months ago
hashimotos
hi, I’ve now been on Levothyroxine 25 since last June. None of my symptoms have changed. GP has just increased it to 50 and said to retest in 8 weeks. I have been asking for increase for quite a while as my level was still in the upper range of normal last test I had in October . My levels had been
hi, I’ve now been on Levothyroxine 25 since last June. None of my symptoms have changed. GP has just increased it to 50 and said to retest in 8 weeks. I have been asking for increase for quite a while as my level was still in the upper range of normal last test I had in October . My levels had been
Ozzy77
in
Thyroid UK
4 months ago
Is there such a thing as too fast of a recovery of T on iADT 🫨
After 2 years of ADT, I decided against continuing on that for life and to initiate iADT. Otherwise known as "taking a vacation".I am now 10 weeks without ADT, and my testosterone is already at 104. My questions this time are for others here who have had a similarly quick return of testosterone. I
After 2 years of ADT, I decided against continuing on that for life and to initiate iADT. Otherwise known as "taking a vacation".I am now 10 weeks without ADT, and my testosterone is already at 104. My questions this time are for others here who have had a similarly quick return of testosterone. I
Lewellen
in
Advanced Prostate Cancer
4 months ago
I don't know what to do anymore.
The last time I was here was about 9 months ago. For a reference here is a link to a thread I posted in before. https://healthunlocked.com/my-ocd/posts/149552410/my-ocd-is-sabotaging-my-attempts-to-treat-my-anxiety-and-depression.?responses=149622964 After I was hospitalized for 10 days, I lost my
The last time I was here was about 9 months ago. For a reference here is a link to a thread I posted in before. https://healthunlocked.com/my-ocd/posts/149552410/my-ocd-is-sabotaging-my-attempts-to-treat-my-anxiety-and-depression.?responses=149622964 After I was hospitalized for 10 days, I lost my
Metastar
in
My OCD Community
4 months ago
How many estrogen patches should I use?
I had a nice breakthrough today. 😀 I collected all of the available data on the number of estrogen patches that the studies have used, and plotted the measured serum estradiol level versus total milligrams of estrogen used every week. I was pleasantly surprised when all five of the data points
I had a nice breakthrough today. 😀 I collected all of the available data on the number of estrogen patches that the studies have used, and plotted the measured serum estradiol level versus total milligrams of estrogen used every week. I was pleasantly surprised when all five of the data points
janebob99
in
Advanced Prostate Cancer
4 months ago
How many estrogen patches to use?
I had a nice breakthrough today. 😀 I collected all of the available data on the number of estrogen patches that the studies have used, and plotted the measured serum estradiol level versus total milligrams of estrogen used every week. I was pleasantly surprised when all five of the data points
I had a nice breakthrough today. 😀 I collected all of the available data on the number of estrogen patches that the studies have used, and plotted the measured serum estradiol level versus total milligrams of estrogen used every week. I was pleasantly surprised when all five of the data points
janebob99
in
Prostate Cancer Network
4 months ago
Need a group therapy or people to chat about social anxiety disorder. Thanks
Hi, I am EL and suffer from social anxiety disorder. I am introverted and fear being exposed to the public, interacting with people for more than a few minutes, or even struggle looking at people in the eyes. I tend to get my hands and armpits sweaty when I get anxious along with shortness of breath.
Hi, I am EL and suffer from social anxiety disorder. I am introverted and fear being exposed to the public, interacting with people for more than a few minutes, or even struggle looking at people in the eyes. I tend to get my hands and armpits sweaty when I get anxious along with shortness of breath.
PapaRocky39
in
Anxiety and Depression Support
9 months ago
Selenium Supplementation in Patients with Hashimoto Thyroiditis
I found this paper and thought I'll share. This is for patients with hashis, who are not yet on thyroid hormone replacement. https://pubmed.ncbi.nlm.nih.gov/38243784/
I found this paper and thought I'll share. This is for patients with hashis, who are not yet on thyroid hormone replacement. https://pubmed.ncbi.nlm.nih.gov/38243784/
buddy99
in
Thyroid UK
4 months ago
HRT FET - Day of transfer?
Hi everyone and thanks for the lovely support in this group - it’s been a comfort reading all the previous posts. I’m doing my first HRT FET, and just wondering around what day of the cycle people’s transfers were? My plan says to take oestrogen from day 1, then have a scan on day 8, and that’s it
Hi everyone and thanks for the lovely support in this group - it’s been a comfort reading all the previous posts. I’m doing my first HRT FET, and just wondering around what day of the cycle people’s transfers were? My plan says to take oestrogen from day 1, then have a scan on day 8, and that’s it
Learningdaybyday
in
Fertility Network UK
4 months ago
PSA vs Testosterone plot has large scatter, but still confirms Morgentaler's Saturation Model.
Here are two plots comparing PSA values to Testosterone levels taken from a pair of large data sets. What is striking is the large amount of scatter in the individual data from both datasets, with factors of 2-6 X deviations from the average (or median) values. The upper plot has N = 255 data points
Here are two plots comparing PSA values to Testosterone levels taken from a pair of large data sets. What is striking is the large amount of scatter in the individual data from both datasets, with factors of 2-6 X deviations from the average (or median) values. The upper plot has N = 255 data points
janebob99
in
Prostate Cancer Network
4 months ago
deciding whether to do pluvicto with hemoglobin around 8
Metastatic prostate cancer to multiple lymph nodes, lungs, bone Mets to spine, ribs, pelvis, femur. PSA 22. Gleason 9. ADT for 7 years, failed zytiga after being on it for 3 years, failed 3 rounds of doxetaxol this past fall. Radiation treatments to pelvis in 2021 and spine, hip in 2023. Had BRCA mutations
Metastatic prostate cancer to multiple lymph nodes, lungs, bone Mets to spine, ribs, pelvis, femur. PSA 22. Gleason 9. ADT for 7 years, failed zytiga after being on it for 3 years, failed 3 rounds of doxetaxol this past fall. Radiation treatments to pelvis in 2021 and spine, hip in 2023. Had BRCA mutations
LJGD
in
Advanced Prostate Cancer
4 months ago
Low-T is associated with worse Prostate Cancer Specific Mortality probability after 6 months of ADT: Part III
Here are comparisons of the
Prostate Cancer Specific Mortality (PCSM) probability (%
) for two different testosterone levels (
Low-T and Normal-T
) and four different
Times After PSA Failure
from the Kaplan-Meier plot previously posted. (Atkins 2018). The median testosterone for
Here are comparisons of the
Prostate Cancer Specific Mortality (PCSM) probability (%
) for two different testosterone levels (
Low-T and Normal-T
) and four different
Times After PSA Failure
from the Kaplan-Meier plot previously posted. (Atkins 2018). The median testosterone for
janebob99
in
Prostate Cancer Network
4 months ago
Low-T is associated with worse Prostate Cancer Specific Mortality probability after 6 months of ADT: Part II
Here are comparisons of the Prostate Cancer Specific Mortality (PCSM) probability (%) for two different testosterone levels (Low-T and Normal-T)and three different Times After PSA Failure from Atkins (2018). he median testosterone for the Low-T group is T = 162 ng/dL [120-236], and I assumed an average
Here are comparisons of the Prostate Cancer Specific Mortality (PCSM) probability (%) for two different testosterone levels (Low-T and Normal-T)and three different Times After PSA Failure from Atkins (2018). he median testosterone for the Low-T group is T = 162 ng/dL [120-236], and I assumed an average
janebob99
in
Prostate Cancer Network
4 months ago
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