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Gaucher disease type 1 (GD1)
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Are Functional Motor Symptoms Influenced by Glutamate and Glutamine Fluctuations?
I was reading an old post and someone commented about this, so naturally I asked the question and found this study: https://www.neurologylive.com/view/functional-motor-symptoms-influenced-glutamate-glutamine-fluctuations Interesting reading and saying that the "functional movements" are down to biology
I was reading an old post and someone commented about this, so naturally I asked the question and found this study: https://www.neurologylive.com/view/functional-motor-symptoms-influenced-glutamate-glutamine-fluctuations Interesting reading and saying that the "functional movements" are down to biology
Lady4
in
Functional Neurological Disorder - FND Hope
4 months ago
Dicyclomine will work with Docetaxel ?
Will this work ? https://www.genengnews.com/topics/cancer/ibs-drug-restores-chemotherapy-effectiveness-against-resistant-prostate-cancer/
Will this work ? https://www.genengnews.com/topics/cancer/ibs-drug-restores-chemotherapy-effectiveness-against-resistant-prostate-cancer/
Manilo
in
Advanced Prostate Cancer
4 months ago
We could tell in advance if enzalutamide works on a patient: computational biology
hopefully it will be clinically tested soon ”For the study in Nature Communications, Mitrofanova's team developed computational algorithms to discover why the prostate cancer drug enzalutamide (sold under the brand name Xtandi) never works for some patients and why it eventually stops working in others
hopefully it will be clinically tested soon ”For the study in Nature Communications, Mitrofanova's team developed computational algorithms to discover why the prostate cancer drug enzalutamide (sold under the brand name Xtandi) never works for some patients and why it eventually stops working in others
Maxone73
in
Advanced Prostate Cancer
4 months ago
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Low Testosterone and value of continuing Hormone Therapy
83 year old male with a question: My understanding is that the role of hormone therapy is to lower one’s testosterone level. Does hormone therapy provide additional benefits in fighting prostate cancer beyond lowering testosterone levels? I was diagnosed with high grade prostate cancer (Gleason 10
83 year old male with a question: My understanding is that the role of hormone therapy is to lower one’s testosterone level. Does hormone therapy provide additional benefits in fighting prostate cancer beyond lowering testosterone levels? I was diagnosed with high grade prostate cancer (Gleason 10
saniku
in
Advanced Prostate Cancer
4 months ago
need some guidance, feeling desperate..
My husband has advanced, Stage IV castration resistant prostate cancer. When he was diagnosed in May 2022 his PSA was 4700, he has widespread bone metastases. He stopped responding to Docetaxel, Pluvicto and is now not responding to Cabazitaxel, his PSA is now over 700. He is feeling good, no pain
My husband has advanced, Stage IV castration resistant prostate cancer. When he was diagnosed in May 2022 his PSA was 4700, he has widespread bone metastases. He stopped responding to Docetaxel, Pluvicto and is now not responding to Cabazitaxel, his PSA is now over 700. He is feeling good, no pain
Kiki27
in
Advanced Prostate Cancer
4 months ago
Extra steroids?
Having had my first cold since before the pandemic after Christmas, I went off the to the doctors about 10 days ago because although I felt I'd recovered I was deaf in one ear and had sticky eyes. One ear hadn't 'popped' on the flight out or back to the UK and once the cold kicked in it got worse. Currently
Having had my first cold since before the pandemic after Christmas, I went off the to the doctors about 10 days ago because although I felt I'd recovered I was deaf in one ear and had sticky eyes. One ear hadn't 'popped' on the flight out or back to the UK and once the cold kicked in it got worse. Currently
ladygigger
in
PMRGCAuk
4 months ago
Not PCa related but sounds like a very promising approach
When I read "advanced pancreatic cancer" and "overall disease control of 94%" in the same document...I feel like smiling.... https://ascopost.com/news/april-2024/advanced-pancreatic-cancer-oncolytic-virus-based-immunostimulatory-gene-therapy-plus-chemotherapy/
When I read "advanced pancreatic cancer" and "overall disease control of 94%" in the same document...I feel like smiling.... https://ascopost.com/news/april-2024/advanced-pancreatic-cancer-oncolytic-virus-based-immunostimulatory-gene-therapy-plus-chemotherapy/
Maxone73
in
Advanced Prostate Cancer
2 months ago
Creatine
I am on Ursofalk and very well fortunately. I take Bezafibrate for itch (life saver). I have embark on a fitness journey of Crossfit and after 12 months wish to improve even more. I am advised by my coach to take Creatine and that this is natural and improves performance and muscle recovery. Anyone
I am on Ursofalk and very well fortunately. I take Bezafibrate for itch (life saver). I have embark on a fitness journey of Crossfit and after 12 months wish to improve even more. I am advised by my coach to take Creatine and that this is natural and improves performance and muscle recovery. Anyone
amt50
in
PBC Foundation
4 months ago
Getting on with life.
My prostate has been removed, my psa is rising. I am not on medication. Basically, just getting on with life. Refusing to let this nonsense get me down. Thoughts anyone ?
My prostate has been removed, my psa is rising. I am not on medication. Basically, just getting on with life. Refusing to let this nonsense get me down. Thoughts anyone ?
Scouse0151
in
Advanced Prostate Cancer
4 months ago
Selegeline/RBD?
It's often said that all of the treatments currently in use for Parkinson's offer symptomatic relief only, and do not affect underlying pathology. However, a recent study suggests selegeline use impacts white matter microstructure and could be neuroprotective. I know white matter abnormalities have been
It's often said that all of the treatments currently in use for Parkinson's offer symptomatic relief only, and do not affect underlying pathology. However, a recent study suggests selegeline use impacts white matter microstructure and could be neuroprotective. I know white matter abnormalities have been
Rufous2
in
Cure Parkinson's
4 months ago
Google Research created an AI system that outperforms human doctors at diagnosing through conversation.
Google Research created an AI system that outperforms human doctors at diagnosing through conversation. https://blog.research.google/2024/01/amie-research-ai-system-for-diagnostic_12.html The Articulate Medical Intelligence Explorer (AMIE) is built on a Google LLM, and it's been optimized for "diagnostic
Google Research created an AI system that outperforms human doctors at diagnosing through conversation. https://blog.research.google/2024/01/amie-research-ai-system-for-diagnostic_12.html The Articulate Medical Intelligence Explorer (AMIE) is built on a Google LLM, and it's been optimized for "diagnostic
Darryl
Partner
in
Advanced Prostate Cancer
4 months ago
Flare
Thursday, my husband had his follow-up appointment with Oncologist. I was very alarmed at some of his blood test results. His PSA went up to 1600. Doctor said other blood work was to be expected. I researched surged in PSA and found this, The PSA flare is a well-known phenomenon. The post chemotherapy
Thursday, my husband had his follow-up appointment with Oncologist. I was very alarmed at some of his blood test results. His PSA went up to 1600. Doctor said other blood work was to be expected. I researched surged in PSA and found this, The PSA flare is a well-known phenomenon. The post chemotherapy
MsHope
in
Advanced Prostate Cancer
4 months ago
xtandi failing?
In September last year my PSA was 0.06. Three months later PSA was 0.09. I asked my doctor if xtandi was failing. He told me not necessarily, once your PSA reached its lowest point, it tends to go up and down before it settles down. He told me they would check my PSA in six weeks, six weeks later
In September last year my PSA was 0.06. Three months later PSA was 0.09. I asked my doctor if xtandi was failing. He told me not necessarily, once your PSA reached its lowest point, it tends to go up and down before it settles down. He told me they would check my PSA in six weeks, six weeks later
Echotango51
in
Advanced Prostate Cancer
4 months ago
Barry
Hi, Diagnosed with advanced prostate cancer stage 4 gleeson score 4+4, having six monthly degarelix injections, had bad side effects on second injection upset stomach diorea feeling very drained, wondering if 3 monthly injections would be better less chemical in system?
Hi, Diagnosed with advanced prostate cancer stage 4 gleeson score 4+4, having six monthly degarelix injections, had bad side effects on second injection upset stomach diorea feeling very drained, wondering if 3 monthly injections would be better less chemical in system?
littlemount
in
Advanced Prostate Cancer
4 months ago
prescription
hi Every time I collect my prescription they give me my urso like this I was seeing if anybody else has this? I feel like when I change too the next box I get a pain on my liver side for a few days and itch a little more then it goes away same thing happens again when I start over again!
hi Every time I collect my prescription they give me my urso like this I was seeing if anybody else has this? I feel like when I change too the next box I get a pain on my liver side for a few days and itch a little more then it goes away same thing happens again when I start over again!
Lena2011
in
PBC Foundation
4 months ago
FDA alert re: denosumab
This was issued specifically re: Prolia, with no mention of Xgeva. However patients should be alerted, and of course don't change your medications without first speaking to your doctor about this. https://www.fda.gov/drugs/drug-safety-and-availability/fda-adds-boxed-warning-increased-risk-severe-hypocalcemia-patients-advanced-chronic-kidney-disease
This was issued specifically re: Prolia, with no mention of Xgeva. However patients should be alerted, and of course don't change your medications without first speaking to your doctor about this. https://www.fda.gov/drugs/drug-safety-and-availability/fda-adds-boxed-warning-increased-risk-severe-hypocalcemia-patients-advanced-chronic-kidney-disease
dentaltwin
in
Advanced Prostate Cancer
4 months ago
Right phrenic nerve paralysis
Path from RP showed extensive perineural involvement. No other risk factors for phrenic nerve paralysis. Haven't talked to MO yet, but sure concerned it's tumor invasion. PSA still <0.04.
Path from RP showed extensive perineural involvement. No other risk factors for phrenic nerve paralysis. Haven't talked to MO yet, but sure concerned it's tumor invasion. PSA still <0.04.
rfgh20
in
Advanced Prostate Cancer
4 months ago
Interesting Article: Promising new remedies for Parkinson's disease
Update:
I read and researched as I was posting this. I am happy they put NR and PEA in their article, but I think they got a little over their skis stating they had found a "
A dynamic quartet
" [u]
Update Again! Please see Park Bear's Citicoline Warning
[/u] https://healthunlocked.com
Update:
I read and researched as I was posting this. I am happy they put NR and PEA in their article, but I think they got a little over their skis stating they had found a "
A dynamic quartet
" [u]
Update Again! Please see Park Bear's Citicoline Warning
[/u] https://healthunlocked.com
Bolt_Upright
in
Cure Parkinson's
4 months ago
My MO suspects that I am non-metastatic, castration resistant but will not approve any treatment until metastases develop.
Gleason 9 at diagnosis, BRACA 2 germline and somatic. RP five years ago but cancer escaped the capsule; PSA of around 2.5 after surgery. Had radiation to pelvic area a few months later along with Eligard injection. Renewed Eligard after 3 months and PSA went down to undetectable. T was close to zero
Gleason 9 at diagnosis, BRACA 2 germline and somatic. RP five years ago but cancer escaped the capsule; PSA of around 2.5 after surgery. Had radiation to pelvic area a few months later along with Eligard injection. Renewed Eligard after 3 months and PSA went down to undetectable. T was close to zero
Balsam01
in
Advanced Prostate Cancer
4 months ago
Triglycerides
I’m very pleased to say my total cholesterol has gone from 6.4 to 4.6 from March this year to August. I worked hard with diet mainly and exercise. However my triglycerides weren’t included in this blood test. Has anyone found that due to their thyroid problems that their triglycerides are raised?
I’m very pleased to say my total cholesterol has gone from 6.4 to 4.6 from March this year to August. I worked hard with diet mainly and exercise. However my triglycerides weren’t included in this blood test. Has anyone found that due to their thyroid problems that their triglycerides are raised?
292426
in
Thyroid UK
9 months ago
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