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Addition of an ARSI to standard ADT significantly increases the risk of fractures and falls in men with prostate cancer
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Graham49
in
Advanced Prostate Cancer
4 months ago
Discoid Lupus
Hello Everyone, I have been suffering with discoid lupus for 5 years now. i have had some pretty nasty flare ups since being diagnosed. One flare up resulted in having to spend 2 weeks in hospital. I recently had another flare up… After nearly 12 months in remission… And I started to get bald patches
Hello Everyone, I have been suffering with discoid lupus for 5 years now. i have had some pretty nasty flare ups since being diagnosed. One flare up resulted in having to spend 2 weeks in hospital. I recently had another flare up… After nearly 12 months in remission… And I started to get bald patches
Beryl2485
in
LUPUS UK
7 months ago
Cortisol test result
Hi, I have just had some blood test results come back today. Currently on 5.5mg, but have been taking 6mg (Sat 30th..Sun, Mon, Tues) as have had lots going on, bit stressful but good stress not bad! the 0.5mg did help. All results are ok including PV, ESR, CRP. Also had a basal cortisol test (partially
Hi, I have just had some blood test results come back today. Currently on 5.5mg, but have been taking 6mg (Sat 30th..Sun, Mon, Tues) as have had lots going on, bit stressful but good stress not bad! the 0.5mg did help. All results are ok including PV, ESR, CRP. Also had a basal cortisol test (partially
Saffron23
in
PMRGCAuk
4 months ago
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'Wednesday Word"
Since my question yesterday was concerning 'brain fog', I thought my word for today should be [u][i]
encephalopathy
[/i][/u] - here are specifics about the word This is a blanket term referring to any brain dysfunction. It can commonly be called 'brain fog'. However, [u][i]
encephalopathy
Since my question yesterday was concerning 'brain fog', I thought my word for today should be [u][i]
encephalopathy
[/i][/u] - here are specifics about the word This is a blanket term referring to any brain dysfunction. It can commonly be called 'brain fog'. However, [u][i]
encephalopathy
DonnaBoll
Administrator
in
PBC Foundation
4 months ago
Liver Ultrasound Question
Hello! I had an abdominal ultrasound today including my liver due to a recent blood test showing very high on all the liver tests… my GP is suspecting Non-alcoholic fatty liver… I know I have to wait for the ultrasound report to come back, but the radiologist who did the scan said that my liver was
Hello! I had an abdominal ultrasound today including my liver due to a recent blood test showing very high on all the liver tests… my GP is suspecting Non-alcoholic fatty liver… I know I have to wait for the ultrasound report to come back, but the radiologist who did the scan said that my liver was
Hidden
in
British Liver Trust
7 months ago
Heart Pain
I wonder if somebody can assist with a question. I'm a 46 year old with a minor mitral valve prolapse. Possible sinus nerve damage on the lower ventricle but minor. I'm not on medication. There is no known 'major' issue or treatment plan suggested by cardiologist. I am very fit with low heart beat. Have
I wonder if somebody can assist with a question. I'm a 46 year old with a minor mitral valve prolapse. Possible sinus nerve damage on the lower ventricle but minor. I'm not on medication. There is no known 'major' issue or treatment plan suggested by cardiologist. I am very fit with low heart beat. Have
MathewHerbert
in
Atrial Fibrillation Support
2 months ago
PSA after chemo # 4
Hi My husbands last chemo was # 3 and PSA was 0.14, he just got the results from Chemo # 4 and it was at 0.12. This is the slowest decline if you look in the profile Iisted all his PSA results. Should we be worried that this last one barely moved ? Or is this slower decline good news? Thanks for any
Hi My husbands last chemo was # 3 and PSA was 0.14, he just got the results from Chemo # 4 and it was at 0.12. This is the slowest decline if you look in the profile Iisted all his PSA results. Should we be worried that this last one barely moved ? Or is this slower decline good news? Thanks for any
positive-thinking
in
Advanced Prostate Cancer
4 months ago
GP appointment and blood tests - will recent steroid injection skew results?
Afternoon everyone, I had a GP appointment yesterday to discuss my symptoms. Went through everything that has happened since the summer. She sent me for blood tests today which included CRP, ESR, Rheumatoid factor and various other tests relating to autoimmune conditions. She insisted I call back for
Afternoon everyone, I had a GP appointment yesterday to discuss my symptoms. Went through everything that has happened since the summer. She sent me for blood tests today which included CRP, ESR, Rheumatoid factor and various other tests relating to autoimmune conditions. She insisted I call back for
MsWhistledown
in
PMRGCAuk
7 months ago
rheumatoid arthritis
Hi I’m Lynne. I’ve had Rheumatoid Arthritis for around 5 years. I’m on (tocilizumab) and Methotrexate injections once a week plus 10 mg steroids . I’ve had lots of falls because of my knee giving way. I’m trying to build up my muscles but finding this difficult because I’ve got a tear in shoulder from
Hi I’m Lynne. I’ve had Rheumatoid Arthritis for around 5 years. I’m on (tocilizumab) and Methotrexate injections once a week plus 10 mg steroids . I’ve had lots of falls because of my knee giving way. I’m trying to build up my muscles but finding this difficult because I’ve got a tear in shoulder from
linnypin1
in
NRAS
7 months ago
How Much Carbidopa Levodopa After 5-10 Years? Any other meds?
I am about to "celebrate" the six year anniversary of my Parkinson's disease diagnosis. I currently take five 25/100 Carbidopa Levodopa tablets per day, usually around 9:00 a.m., noon, 3:00 p.m., 6:00 p.m., and 9:00 p.m. although timing varies slightly from day to day. Lately, I have noticed that I
I am about to "celebrate" the six year anniversary of my Parkinson's disease diagnosis. I currently take five 25/100 Carbidopa Levodopa tablets per day, usually around 9:00 a.m., noon, 3:00 p.m., 6:00 p.m., and 9:00 p.m. although timing varies slightly from day to day. Lately, I have noticed that I
jimcaster
in
Cure Parkinson's
4 months ago
Hemorrhoids from higher cholesterol
I thought I'd ask if this is common for other people. I suspect my Hemorrhoids have got quite bad as a result of slightly underactive thyroid. My cholesterol is mildly high - 5.7 when it should be below 5. Also I have gilberts syndrome which is high bilirubin. When I fasted or went more than 6 hrs without
I thought I'd ask if this is common for other people. I suspect my Hemorrhoids have got quite bad as a result of slightly underactive thyroid. My cholesterol is mildly high - 5.7 when it should be below 5. Also I have gilberts syndrome which is high bilirubin. When I fasted or went more than 6 hrs without
SteveT3
in
Thyroid UK
7 months ago
Crohns/IBD
I have undiagnosed Crohns/IBD and continuous flares. I had surgery in 2011 resection of 20cm colon. What treatments are effective?
I have undiagnosed Crohns/IBD and continuous flares. I had surgery in 2011 resection of 20cm colon. What treatments are effective?
Lalande
in
Thyroid UK
4 months ago
Rising PCA - on ADT Holiday
Diagnosed Stage 4 oligometastatic (low volume) PCA in 2021. Gleason 7, 4+3 . Completed RT and 18 months on ADT (Nubeqa) paused the ADT in September after PSA non detectable and a fresh set of scans showed no “evidence of disease”. Continued to do bloodwork quarterly and PSA remained at 0. Until
Diagnosed Stage 4 oligometastatic (low volume) PCA in 2021. Gleason 7, 4+3 . Completed RT and 18 months on ADT (Nubeqa) paused the ADT in September after PSA non detectable and a fresh set of scans showed no “evidence of disease”. Continued to do bloodwork quarterly and PSA remained at 0. Until
Kkash
in
Advanced Prostate Cancer
4 months ago
FDA clearance for SYNC-T SV-102, a pioneering combo immunotherapy for Metastatic Castrate-Resistant Prostate Cancer
Source link: https://finance.yahoo.com/news/syncromune-inc-announces-fda-clearance-232200345.html SYNC-T SV-102 Therapy combines partial tumor oncolysis with a fixed-dose combination multi-target biologic drug to provide a novel, personalized therapeutic approach for the treatment of metastatic
Source link: https://finance.yahoo.com/news/syncromune-inc-announces-fda-clearance-232200345.html SYNC-T SV-102 Therapy combines partial tumor oncolysis with a fixed-dose combination multi-target biologic drug to provide a novel, personalized therapeutic approach for the treatment of metastatic
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
Weight problems and insensitive people
I've been so self conscious since gaining so much weight from my underactive thyroid that I'm basically a hermit in my own home, I barely go outdoors, for fear of being called up on my weight gain, or "looking well". Today I decided to go outdoors only to bump into an old acquaintance who couldn't resist
I've been so self conscious since gaining so much weight from my underactive thyroid that I'm basically a hermit in my own home, I barely go outdoors, for fear of being called up on my weight gain, or "looking well". Today I decided to go outdoors only to bump into an old acquaintance who couldn't resist
Foxxyyh
in
Thyroid UK
7 months ago
Confused
UPDATE: April 5, 2024 Yesterday was very disappointing as my husbands PSA increased again by 183 points, last month his PSA was 1546 and now it is 1730. All his other CBC results were good. His Alkaline Phosphatase increased 6 points, last month 127 and now 133 but still in range of 40-150. Questioned
UPDATE: April 5, 2024 Yesterday was very disappointing as my husbands PSA increased again by 183 points, last month his PSA was 1546 and now it is 1730. All his other CBC results were good. His Alkaline Phosphatase increased 6 points, last month 127 and now 133 but still in range of 40-150. Questioned
MsHope
in
Advanced Prostate Cancer
4 months ago
Psa level
Just came off degarlix as psa level was rising, now on xtadi apalutamide how long does it take for psa level to fall and by how much?
Just came off degarlix as psa level was rising, now on xtadi apalutamide how long does it take for psa level to fall and by how much?
littlemount
in
Advanced Prostate Cancer
4 months ago
fibroscan score 7.9 f1 finrosis
I don’t understand this report as 7.9 Kos should indicate f2 fibrosis not f1 also the did not give me a cap score Not overweight very fit active no alcohol or any kind of hepatitis not hereditary conditions either So quite confused
I don’t understand this report as 7.9 Kos should indicate f2 fibrosis not f1 also the did not give me a cap score Not overweight very fit active no alcohol or any kind of hepatitis not hereditary conditions either So quite confused
TacosPizzaIcecream
in
British Liver Trust
4 months ago
My gfr is om 15 % already but I dont want dialysis
Hi everyone happy Easter, hope everyone is well so I'm already at 15 % gfr and so worried I do want to get in dialysis I want to go straight to the transplants . I when to recently get blood work at my gyno and it should my gfr 15 % but I have a cold and was a bit dehydrated since I drank k 2 bottle
Hi everyone happy Easter, hope everyone is well so I'm already at 15 % gfr and so worried I do want to get in dialysis I want to go straight to the transplants . I when to recently get blood work at my gyno and it should my gfr 15 % but I have a cold and was a bit dehydrated since I drank k 2 bottle
jennifer24
in
Early CKD Support
4 months ago
Discoid lupus
Hi. I have just got results of biopsy. I have discoid lupus, I have also had full blood checks and came back clear. Every where I read says discoid lupus only affects the skin. But I have been experiencing joint pain pretty much every part of my body where there's joints, stiffness, extreme fatigue.
Hi. I have just got results of biopsy. I have discoid lupus, I have also had full blood checks and came back clear. Every where I read says discoid lupus only affects the skin. But I have been experiencing joint pain pretty much every part of my body where there's joints, stiffness, extreme fatigue.
Kddp
in
LUPUS UK
7 months ago
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