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Erleada Update
Hi All, After becoming resitant to Lupron, Erleada and Xgeva were added. I have been on all three meds 4 months. My PSA went from 13.4 to 4.4 in 6 weeks. Over the next 10 weeks, my PSA dropped from 4.4 to 2.5.
Hi All, After becoming resitant to Lupron, Erleada and Xgeva were added. I have been on all three meds 4 months. My PSA went from 13.4 to 4.4 in 6 weeks. Over the next 10 weeks, my PSA dropped from 4.4 to 2.5.
MJCA
in
Advanced Prostate Cancer
5 years ago
Moving on up,whats next.
Diagnosed 2016 stage 4. 8 gleason 12 psa. Rad prostectomy 37 sessions radiation lupron casodex etc. The past 13 mos on zytiga and elegard doing well tolerating for the most part. Although i went from 4 mos ago from a 0.006 feb 2019 undetectable psa to a 0.009. Still no concern to now 5/24/19 to a 0.065
Diagnosed 2016 stage 4. 8 gleason 12 psa. Rad prostectomy 37 sessions radiation lupron casodex etc. The past 13 mos on zytiga and elegard doing well tolerating for the most part. Although i went from 4 mos ago from a 0.006 feb 2019 undetectable psa to a 0.009. Still no concern to now 5/24/19 to a 0.065
Costarica1961
in
Advanced Prostate Cancer
5 years ago
Proton Pump Inhibitors (ppi's) - here is a short, digestible but expert article.
The Beers Criteria were updated in 2015 to include PPIs and the potential risk of CDAD and bone
fractures
in the geriatric population.
The Beers Criteria were updated in 2015 to include PPIs and the potential risk of CDAD and bone
fractures
in the geriatric population.
gutlesswonder
in
Oesophageal & Gastric Cancer
5 years ago
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Crippled by shin splints
So I’ve been doing couch to 5k for around 8 weeks now, I’m currently on week four (progressing at my own pace). So the first couple of weeks my shins were unbearable I went to a running shop for a gait analysis and bought some trainers following their advice. Although I still couldn’t make it through
So I’ve been doing couch to 5k for around 8 weeks now, I’m currently on week four (progressing at my own pace). So the first couple of weeks my shins were unbearable I went to a running shop for a gait analysis and bought some trainers following their advice. Although I still couldn’t make it through
Probablythetruth
in
Couch to 5K
5 years ago
GRAVES AND THYROTOXICOSIS : SKELETON AND CALCIUM METABOLISM
Fractures
are uncommon, with the most frequent being collapsed vertebra in a chronically thyrotoxic postmenopausal woman. Skeletal mass is augmented after therapy [300-301]. Treatment restores the density in younger patients, but not usually in the elderly [300].
Fractures
are uncommon, with the most frequent being collapsed vertebra in a chronically thyrotoxic postmenopausal woman. Skeletal mass is augmented after therapy [300-301]. Treatment restores the density in younger patients, but not usually in the elderly [300].
ling
in
Thyroid UK
5 years ago
Bone mets/fracture
Once you start having bone
fractures
/Mets does that mean your bones are more brittle now? I ask as my husband and I used to do a lot of cycling and I’m just wondering if I fall would I be possibly be breaking more bones? I know that can happen without having mbc but am I pushing it ?
Once you start having bone
fractures
/Mets does that mean your bones are more brittle now? I ask as my husband and I used to do a lot of cycling and I’m just wondering if I fall would I be possibly be breaking more bones? I know that can happen without having mbc but am I pushing it ?
Onie54
in
SHARE Metastatic Breast Cancer
5 years ago
Updated guidance from RMOC (Regional Medicines Optimisation Committee (South)
The risks of over-treatment with thyroid hormones include atrial [/i][i]fibrillation, osteoporosis and bone
fractures
, and the risks of under treatment are also significant."[/i] We would like to thank all the thyroid groups that had an input into this work, especially the Thyroid Trust.
The risks of over-treatment with thyroid hormones include atrial [/i][i]fibrillation, osteoporosis and bone
fractures
, and the risks of under treatment are also significant."[/i] We would like to thank all the thyroid groups that had an input into this work, especially the Thyroid Trust.
lynmynott
Thyroid UK
in
Thyroid UK
5 years ago
X ray on foot
My doctor sent me for a x ray on my foot they told me to see my doc in 7 to 10 days if i had a fracture would they have told me there and then at the hospital
My doctor sent me for a x ray on my foot they told me to see my doc in 7 to 10 days if i had a fracture would they have told me there and then at the hospital
Spudster1
in
Pain Concern
5 years ago
On Lupron and chemo and PSA went from .28 to .48 in two weeks
My husband started ADT in January with Firmagon, two months in a row. His PSA dropped from 9.79 to .69 in that time. In March they switched to a six month Lupron injection, which brought it down to .28. Two weeks ago, he started chemo, and yesterday he had a follow up and now his PSA is .48! Is this
My husband started ADT in January with Firmagon, two months in a row. His PSA dropped from 9.79 to .69 in that time. In March they switched to a six month Lupron injection, which brought it down to .28. Two weeks ago, he started chemo, and yesterday he had a follow up and now his PSA is .48! Is this
Wyldhare22
in
Advanced Prostate Cancer
5 years ago
***Start Of next chapter***
Good morning my Brothers, today I start my Provenge treatments . I don't think I have the same mindset from when I was first diagnosed with the Beast. We all go through the gambit of rollercoaster emotions, but I know it's a fight to the end. I am kind of looking forward to this treatment sounds crazy
Good morning my Brothers, today I start my Provenge treatments . I don't think I have the same mindset from when I was first diagnosed with the Beast. We all go through the gambit of rollercoaster emotions, but I know it's a fight to the end. I am kind of looking forward to this treatment sounds crazy
leo2634
in
Advanced Prostate Cancer
5 years ago
"Minimizing Morbidity and Maximizing Outcomes w/ ADT by Laurence Klotz, MD Aug 2018"
Here is more discussion of Intermittent ADT and Firmagon vs Lupron others might find interesting. https://grandroundsinurology.com/minimizing-morbidity-and-maximizing-outcomes-with-adt/ I'll say on the front end it involves discussion of mouse studies which I know is controversial, but hopefully there
Here is more discussion of Intermittent ADT and Firmagon vs Lupron others might find interesting. https://grandroundsinurology.com/minimizing-morbidity-and-maximizing-outcomes-with-adt/ I'll say on the front end it involves discussion of mouse studies which I know is controversial, but hopefully there
SuppWife
in
Advanced Prostate Cancer
5 years ago
Shin splints
Hi, I hope I'm in the right place. Today I had to walk home from work as my car is in the garage. After about half a mile I started getting pain in both my shins which very quickly forced me to take a seat at a bus stop. I've done a little bit of researching online and it sounds a lot like shin splints
Hi, I hope I'm in the right place. Today I had to walk home from work as my car is in the garage. After about half a mile I started getting pain in both my shins which very quickly forced me to take a seat at a bus stop. I've done a little bit of researching online and it sounds a lot like shin splints
Blindowl
in
Bone Health and Osteoporosis UK
5 years ago
Rebounder safe exercise?
I'm trying to understand what can strengthen my bones the most effectively without causing
fractures
in my spine. Walking is good. What about gentle bouncing on a rebounder? Has anyone used this, or have any advice?
I'm trying to understand what can strengthen my bones the most effectively without causing
fractures
in my spine. Walking is good. What about gentle bouncing on a rebounder? Has anyone used this, or have any advice?
elery
in
Bone Health and Osteoporosis UK
5 years ago
Taxotere result
Hi My husband dx dec2017 cancer in semical vessels and multiple bone mets.Had rp in Feb 2018 then decaptyl every 3 months, zometa every 6 wks and casodex. Taxotere in October 9 sessions. Onc said bone mets had ' stabilized ..my question is should chemo have done more? Should it have shrunk lesions
Hi My husband dx dec2017 cancer in semical vessels and multiple bone mets.Had rp in Feb 2018 then decaptyl every 3 months, zometa every 6 wks and casodex. Taxotere in October 9 sessions. Onc said bone mets had ' stabilized ..my question is should chemo have done more? Should it have shrunk lesions
Omc64
in
Advanced Prostate Cancer
5 years ago
Two new advanced hormonal agents (apalutamide and enzalutamide) increase survival in metastatic hormone sensitive prostate cancer (mHSPC)
New indications for 2 previously approved drugs - Erleada and Xtandi. I don't have all the details yet on Xtandi, but it is clearly successful for mHSPC. I'll update after the ASCO meeting. Here's what I know so far: https://pcnrv.blogspot.com/2019/05/two-new-advanced-hormonal-agents.html
New indications for 2 previously approved drugs - Erleada and Xtandi. I don't have all the details yet on Xtandi, but it is clearly successful for mHSPC. I'll update after the ASCO meeting. Here's what I know so far: https://pcnrv.blogspot.com/2019/05/two-new-advanced-hormonal-agents.html
Tall_Allen
in
Advanced Prostate Cancer
5 years ago
Would a Nagalase test help??
Is anyone familiar with the Nagalase test? Has anyone had a Nagalase test and would it be useful if you've had a orchiectomy and are still castrate sensitive with PSA <0.01 and T <1.0? We are not comfortable only doing traditional CT's & Bone Scans every 6 months while PSA & T is good. It appears the
Is anyone familiar with the Nagalase test? Has anyone had a Nagalase test and would it be useful if you've had a orchiectomy and are still castrate sensitive with PSA <0.01 and T <1.0? We are not comfortable only doing traditional CT's & Bone Scans every 6 months while PSA & T is good. It appears the
sjc2
in
Advanced Prostate Cancer
5 years ago
A little sunshine for a dark few weeks
My husbands PSA has been going through the roof, in a lot of pain and just not well. He was just prescribed Xtandi. I was able to get his Xtandi for $0 copay with a $25,000/year limit. The only requirement was that we have commercial insurance and agree to receive email information. The disclaimer
My husbands PSA has been going through the roof, in a lot of pain and just not well. He was just prescribed Xtandi. I was able to get his Xtandi for $0 copay with a $25,000/year limit. The only requirement was that we have commercial insurance and agree to receive email information. The disclaimer
Hidden
in
Advanced Prostate Cancer
5 years ago
Looking for advice
I have been slowly reducing my Rayos and doing pretty good. I am down to 12mg from 15mg from December. 2 nights ago I woke in incredible pain in my hip, knee and leg. I could hardly move. I increased my rayos to 14mg then to 15mg before I got any relief. Last night the same thing happened. Last night
I have been slowly reducing my Rayos and doing pretty good. I am down to 12mg from 15mg from December. 2 nights ago I woke in incredible pain in my hip, knee and leg. I could hardly move. I increased my rayos to 14mg then to 15mg before I got any relief. Last night the same thing happened. Last night
Linny3
in
PMRGCAuk
5 years ago
BCR after castration
Has any ones PSA gone on the rise after orchiectomy? I had Casodex for 25 days then a Lupron shot 7.5 then the next month Dec 18 the Dr switched to Eligard stating they changed vendors. The day I got the shot I could hardly walk. Called the Doc the next day he said it should work itself out. After
Has any ones PSA gone on the rise after orchiectomy? I had Casodex for 25 days then a Lupron shot 7.5 then the next month Dec 18 the Dr switched to Eligard stating they changed vendors. The day I got the shot I could hardly walk. Called the Doc the next day he said it should work itself out. After
Shegolf
in
Advanced Prostate Cancer
5 years ago
Atorvastatin
After an x ray they found I had 2 x compound
fractures
too two vertebrae, which I go for a scan to see the cause of it. But I'm convinced that the statins are causing most if the aches and pains. Has anyone had similar issues? Cheers
After an x ray they found I had 2 x compound
fractures
too two vertebrae, which I go for a scan to see the cause of it. But I'm convinced that the statins are causing most if the aches and pains. Has anyone had similar issues? Cheers
Foxtrot07
in
British Heart Foundation
5 years ago
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