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Experiences with
Fenofibrate / Simvastatin
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Advice needed
Hello everyone, I've been following this forum for a couple of years but don't often post. Here is my scenario, diagnosed with PMR in May/June 2016. Put on 10 mg of Pred and fairly instant relief. Had a slow taper , arrived at 6 mg in January 2017 but had a flare so back to 10 mg. It has taken a whole
Hello everyone, I've been following this forum for a couple of years but don't often post. Here is my scenario, diagnosed with PMR in May/June 2016. Put on 10 mg of Pred and fairly instant relief. Had a slow taper , arrived at 6 mg in January 2017 but had a flare so back to 10 mg. It has taken a whole
York54
in
PMRGCAuk
6 years ago
CRPC & Avodart [Dutasteride].
New study below. Some may recall that I'm in favor of shutting off all escape paths while on ADT - e.g. via Zytiga, Casodex, Simvastatin & Avodart. If you are closing the door, close the windows too. The conventional view is that since 5alpha-reductase converts testosterone [T] to dihtdrotestosterone
New study below. Some may recall that I'm in favor of shutting off all escape paths while on ADT - e.g. via Zytiga, Casodex, Simvastatin & Avodart. If you are closing the door, close the windows too. The conventional view is that since 5alpha-reductase converts testosterone [T] to dihtdrotestosterone
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Fenofibrate and kidney:Increase in serum creatinine
Fenofibrate has been used for the management of atherogenic dyslipidaemia for many years. Reports of fenofibrate-associated increases in serum creatinine (SCr) levels raised concerns regarding deleterious effects on renal function. Fenofibrate may not be a nephrotoxic drug. However, a close monitoring
Fenofibrate has been used for the management of atherogenic dyslipidaemia for many years. Reports of fenofibrate-associated increases in serum creatinine (SCr) levels raised concerns regarding deleterious effects on renal function. Fenofibrate may not be a nephrotoxic drug. However, a close monitoring
DRH-sangli
Star
in
Diabetes India
6 years ago
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Statin
I saw my Internist this morning to go over last labs. In discussing my cholesterol, he sent a msg to my GI asking his thoughts on getting back on statin. GI responded quickly & approved as long as they both keep an eye on enzymes. I researched Journal of Lipid Research & looked into their clinical trials
I saw my Internist this morning to go over last labs. In discussing my cholesterol, he sent a msg to my GI asking his thoughts on getting back on statin. GI responded quickly & approved as long as they both keep an eye on enzymes. I researched Journal of Lipid Research & looked into their clinical trials
gwillistexas
in
PBC Foundation
6 years ago
Microvascular angina
Hi All. I am new here (and to forums generally)! In 2012, at the age of 36 I was diagnosed with microvascular angina. It took a long time to get the diagnosis because a few months earlier I had an unexplained DVT which was subsequently attributed to Factor V Leiden. The doctors initially thought it
Hi All. I am new here (and to forums generally)! In 2012, at the age of 36 I was diagnosed with microvascular angina. It took a long time to get the diagnosis because a few months earlier I had an unexplained DVT which was subsequently attributed to Factor V Leiden. The doctors initially thought it
Hidden
in
British Heart Foundation
6 years ago
Jevtana [Cabazitaxel] & Androgen Status.
New Dutch study below. Jevtana is a taxane (as is Taxotere), & was approved by the FDA for men with CRPC in 2010. Typically, in castrate-resistant PCa [CRPC], the cancer remains androgen-sensitive & has found alternative sources. For instance, there is a potential pathway that produces DHT (dihydrotestosterone
New Dutch study below. Jevtana is a taxane (as is Taxotere), & was approved by the FDA for men with CRPC in 2010. Typically, in castrate-resistant PCa [CRPC], the cancer remains androgen-sensitive & has found alternative sources. For instance, there is a potential pathway that produces DHT (dihydrotestosterone
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Tricor
My doctor had just started me on fenofibrate 48 mg..... is anyone else taking this? The brochure in the meds said to be careful and make sure your doctor knows about kidney disease, pbc etc....concerned 😔
My doctor had just started me on fenofibrate 48 mg..... is anyone else taking this? The brochure in the meds said to be careful and make sure your doctor knows about kidney disease, pbc etc....concerned 😔
Pamela4475
in
PBC Foundation
7 years ago
I'm stage4 how did I get here ?
HI My my name is Marge this is the best web site I've found for kidney disease .So glad I found it. This pass July I was diagnosed with stage 3 kidney disease 2 months later I'm stage 4 I don't know how it changed so fast. I have had high blood pressure for 55 years . Seven years ago I was diagnosed
HI My my name is Marge this is the best web site I've found for kidney disease .So glad I found it. This pass July I was diagnosed with stage 3 kidney disease 2 months later I'm stage 4 I don't know how it changed so fast. I have had high blood pressure for 55 years . Seven years ago I was diagnosed
MSTAUF
in
Early CKD Support
7 years ago
Are all Statins bad news?
Atorvastatin 40mg headache . Simvastatin 40mg Could not sleep . Pravastatin 40mg Knee Joint/Back pain. Feeling hot. Going back to doctor next week. Any advice?
Atorvastatin 40mg headache . Simvastatin 40mg Could not sleep . Pravastatin 40mg Knee Joint/Back pain. Feeling hot. Going back to doctor next week. Any advice?
Sheffield6
in
Cholesterol Support
7 years ago
Parkinson's Disease – and Lessons from Biology
Simvastatin as an Anti-Inflammatory and Neuroprotective Agent in Parkinson's Disease Groundbreaking research suggests that the cholesterol lowering drug simvastatin may provide powerful neuroprotection in Parkinson's disease. A little known fact among the public is that statin drugs do more than simply
Simvastatin as an Anti-Inflammatory and Neuroprotective Agent in Parkinson's Disease Groundbreaking research suggests that the cholesterol lowering drug simvastatin may provide powerful neuroprotection in Parkinson's disease. A little known fact among the public is that statin drugs do more than simply
Hidden
in
Cure Parkinson's
7 years ago
Finishing 7 days of flagyl and cripto
Having had a really tender r h side abdomen for a week, dr put me on flagyl and cripto for seven days..finished two days ago My prolapsed bowel op was cancelled 10 days ago, cos there was no bed..ven tho when they phone toboffer me this spot and I explained that I was just starting to have this tenderness
Having had a really tender r h side abdomen for a week, dr put me on flagyl and cripto for seven days..finished two days ago My prolapsed bowel op was cancelled 10 days ago, cos there was no bed..ven tho when they phone toboffer me this spot and I explained that I was just starting to have this tenderness
Hather
in
IBS Network
7 years ago
No where to turn
Hello, I've been on this site just reading posts for a long time now. I've never posted anything as I have so many issues and don't know how or where to begin. Lately I've felt so horrible that I honestly feel like giving up. I have absolutely no quality of life and don't want to suffer any longer. I'll
Hello, I've been on this site just reading posts for a long time now. I've never posted anything as I have so many issues and don't know how or where to begin. Lately I've felt so horrible that I honestly feel like giving up. I have absolutely no quality of life and don't want to suffer any longer. I'll
Jame5263
in
Pain Concern
7 years ago
Pantoprazole vs Simvastatin
I’ve read that Pantoprazole interacts with Simvastatin. Is it ok if take them 4hrs apart?
I’ve read that Pantoprazole interacts with Simvastatin. Is it ok if take them 4hrs apart?
zeny
in
Lung Conditions Community Forum
7 years ago
Feeling confused, frustrated and worried.
An update, I seem to have been writing no positive posts of late. My latest 6 weeks check up at Addenbrookes, again I did not see George Mell, he is only seeing new patients and each time I attend I seem to be more worried and find that I am not getting answers or politician type answers. I even asked
An update, I seem to have been writing no positive posts of late. My latest 6 weeks check up at Addenbrookes, again I did not see George Mell, he is only seeing new patients and each time I attend I seem to be more worried and find that I am not getting answers or politician type answers. I even asked
Jo_Br
in
PBC Foundation
7 years ago
When to take medication?
Hi everyone Please could you advise me when to take my medication. I normally take Lansoprazole about 7 - 7.30 am, breakfast about 8am with 5mg Pred, Calcichew about 12am before lunch, then again about 9pm, then Simvastatin about 10pm. No problems. However, I have now been diagnosed with Angina and
Hi everyone Please could you advise me when to take my medication. I normally take Lansoprazole about 7 - 7.30 am, breakfast about 8am with 5mg Pred, Calcichew about 12am before lunch, then again about 9pm, then Simvastatin about 10pm. No problems. However, I have now been diagnosed with Angina and
Marlenec
in
PMRGCAuk
7 years ago
Husband has pbc.....bilirubin rise
Hello, I'm the wife madly in love and bone shaking fear filled of a husband(68yr) with pbc, totally shocked with the diagnosis 4yrs ago, cirrhosis at that time. Very shocking. Things have been manageable,...varies banded, med, started lactose and xifaxan which cleared encephalopathy. Latest blood work
Hello, I'm the wife madly in love and bone shaking fear filled of a husband(68yr) with pbc, totally shocked with the diagnosis 4yrs ago, cirrhosis at that time. Very shocking. Things have been manageable,...varies banded, med, started lactose and xifaxan which cleared encephalopathy. Latest blood work
Debomo
in
PBC Foundation
7 years ago
Short Lived responder to Urso
I fell I have not been here for ages. I was away on my hols for a fortnight, Granny care has been pretty full on since. My last visit to Addenbrookes confirmed the Anti-GP 210 marked a more progressive journey but support and treatment would be the same. While there had usual blood tests on the day,
I fell I have not been here for ages. I was away on my hols for a fortnight, Granny care has been pretty full on since. My last visit to Addenbrookes confirmed the Anti-GP 210 marked a more progressive journey but support and treatment would be the same. While there had usual blood tests on the day,
Jo_Br
in
PBC Foundation
7 years ago
"Drug Aimed at Inflammation May Lower Risk of Heart Disease and Cancer"
That's the title of a piece in today's NY Times [1]. It must be a dozen years since someone told me that the men who have better survival are those with good albumin levels. Those with <4.0 don't do well. Since diagnosis, I use a lot of polyphenols, which inhibit NFkB. NFkB is chronically activated
That's the title of a piece in today's NY Times [1]. It must be a dozen years since someone told me that the men who have better survival are those with good albumin levels. Those with <4.0 don't do well. Since diagnosis, I use a lot of polyphenols, which inhibit NFkB. NFkB is chronically activated
pjoshea13
in
Advanced Prostate Cancer
7 years ago
One to go!
I am sharing this for all those who are following in the same path and to give hope that, there is light at the end of the tunnel. Yesterday, I moved onto 1mg of prednisolone and after a 14 month tapering regime, there have been no flares to GCA and in the words of the song, "we are almost there". The
I am sharing this for all those who are following in the same path and to give hope that, there is light at the end of the tunnel. Yesterday, I moved onto 1mg of prednisolone and after a 14 month tapering regime, there have been no flares to GCA and in the words of the song, "we are almost there". The
DevonMichael
in
PMRGCAuk
7 years ago
Simvastatin & Docetaxel?
New cell study below. Bottom line: Simvastatin might enhance Taxotere killing potential. -Patrick https://www.ncbi.nlm.nih.gov/pubmed/28803608 BMB Rep. 2017 Aug 11. pii: 3861. [Epub ahead of print] Identification of simvastatin-regulated targets associated with JNK activation in DU145 human prostate
New cell study below. Bottom line: Simvastatin might enhance Taxotere killing potential. -Patrick https://www.ncbi.nlm.nih.gov/pubmed/28803608 BMB Rep. 2017 Aug 11. pii: 3861. [Epub ahead of print] Identification of simvastatin-regulated targets associated with JNK activation in DU145 human prostate
pjoshea13
in
Advanced Prostate Cancer
7 years ago
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