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Estrogen Replacement Therapy
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Is it menopause ?
My story is complicated and confusing. I am 39 now but I think I am getting into menopause very soon.I have severe hot flushes for nearly a month and half now, they are so severe and frequent that I have to sit motionless in front of the AC or fan all the time, even going to the bathroom would trigger
My story is complicated and confusing. I am 39 now but I think I am getting into menopause very soon.I have severe hot flushes for nearly a month and half now, they are so severe and frequent that I have to sit motionless in front of the AC or fan all the time, even going to the bathroom would trigger
veryanxious84
in
Menopause and Perimenopause Support
10 months ago
NDT vs T4 T3 combination therapy
Hello everyone. Please share your experience NDT vs combination therapy. Currently I am on combo but still have symptoms (I have no thyroid). I am doing better on combo than on T4 only. I want to try NDT and see if it will make me feel better. Since both of them mainly contain T4 T3 may I expect significant
Hello everyone. Please share your experience NDT vs combination therapy. Currently I am on combo but still have symptoms (I have no thyroid). I am doing better on combo than on T4 only. I want to try NDT and see if it will make me feel better. Since both of them mainly contain T4 T3 may I expect significant
Alex_N
in
Thyroid UK
3 months ago
Rotigitine Patches
Happy New year everyone. I have had Restless Legs now for many years and in the beginning was given several drugs. Many years ago I went to see Dr Fackrell privately in Bath and he diagnosed me as having severe restless legs and put me on Rotigitine Patches, which over the years have been pretty
Happy New year everyone. I have had Restless Legs now for many years and in the beginning was given several drugs. Many years ago I went to see Dr Fackrell privately in Bath and he diagnosed me as having severe restless legs and put me on Rotigitine Patches, which over the years have been pretty
Gonzo123
in
Restless Legs Syndrome
6 months ago
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Steve 6 and a half years since heart failure.
My heart problems materialised when my customer said to me you look terrible as I wheeled a barrow up a ramp with heavy concrete blocks. Next morning I was in a ward being told I had heart failure. Was a shock and after 2 years on meds was finally sent in for a aortic root and valve replacement. So
My heart problems materialised when my customer said to me you look terrible as I wheeled a barrow up a ramp with heavy concrete blocks. Next morning I was in a ward being told I had heart failure. Was a shock and after 2 years on meds was finally sent in for a aortic root and valve replacement. So
Bobbymrg
in
British Heart Foundation
6 months ago
Bayer and AskBio report data from Parkinson’s disease therapy trial
The bilateral infusions of AB-1005 were well tolerated, without any SAEs linked to the gene therapy or contrast agent. AskBio Parkinson’s and MSA Scientific chair Krystof Bankiewicz said: “These early findings are encouraging and show AB-1005 to be well tolerated in this study in patients with mild
The bilateral infusions of AB-1005 were well tolerated, without any SAEs linked to the gene therapy or contrast agent. AskBio Parkinson’s and MSA Scientific chair Krystof Bankiewicz said: “These early findings are encouraging and show AB-1005 to be well tolerated in this study in patients with mild
Farooqji
in
Cure Parkinson's
3 months ago
Help Please 🙏🏻
Hi everyone, I desperately need the advice of people who can understand my situation. I am afraid for the first time since I became ill in 1990 that I am at my wits end and simply do not know what to do. I had a cavernous haemangioma removed from my nasal cavity in February. I suffered a haemorrhage
Hi everyone, I desperately need the advice of people who can understand my situation. I am afraid for the first time since I became ill in 1990 that I am at my wits end and simply do not know what to do. I had a cavernous haemangioma removed from my nasal cavity in February. I suffered a haemorrhage
CecilyParsley
in
Behçet's UK
24 days ago
Anyone have to multi dose transdermal estrogen cream throughout day.
I am absorbing cream quickly and have to multi dose everyday
I am absorbing cream quickly and have to multi dose everyday
Mccrae
in
Menopause and Perimenopause Support
10 months ago
Oestradial HRT & the thyroid, Lenzetto blood tests
I just wondered if low oestradial affects the thyroid? I have been on HRT since March and my level is still only 197 pmol/L. I use 3 sprays of Lenzetto. I wondered if it could be affecting my thyroid function? I don’t have menopause symptoms, I had bottom of range testosterone, but this is now in range
I just wondered if low oestradial affects the thyroid? I have been on HRT since March and my level is still only 197 pmol/L. I use 3 sprays of Lenzetto. I wondered if it could be affecting my thyroid function? I don’t have menopause symptoms, I had bottom of range testosterone, but this is now in range
CornishChick
in
Thyroid UK
10 months ago
CRISPR 13 (what? you thought I abandoned CRISPR?): very promising proof of concept - Targeting HOXB13 in mPCa by CRISPR/Cas13d- nanoparticle
And people thought it was undruggable....they have already filed for a patent 😲 Researchers developed nanoparticles that can deliver a special type of gene therapy directly to cancer cells in the liver. This system uses a CRISPR technology, not to edit DNA, but to block the RNA of the HOXB13 protein
And people thought it was undruggable....they have already filed for a patent 😲 Researchers developed nanoparticles that can deliver a special type of gene therapy directly to cancer cells in the liver. This system uses a CRISPR technology, not to edit DNA, but to block the RNA of the HOXB13 protein
Maxone73
in
Advanced Prostate Cancer
3 months ago
constipation
years of laxative abuse leaves me with slow bowel going shortly for biofeedback as have no anal function, have to evacuate myself now I’m passing some stool with interference but so bloated and in pain, am I impacted? Starting laxido today, and a stimulant, swore never to laxative use again but scared
years of laxative abuse leaves me with slow bowel going shortly for biofeedback as have no anal function, have to evacuate myself now I’m passing some stool with interference but so bloated and in pain, am I impacted? Starting laxido today, and a stimulant, swore never to laxative use again but scared
Dudders123
in
IBS Network
3 months ago
Thyroid S in UK
Hello everyone. I am a thyroid patient from Armenia, I have no thyroid for the last 6 years. I tried T4 and T4 and T3 combination therapies, but still I feel sick with many symptoms. I would like to try NDT, can you please advise a reliable source to by Thyroid S online in UK? Thank you.
Hello everyone. I am a thyroid patient from Armenia, I have no thyroid for the last 6 years. I tried T4 and T4 and T3 combination therapies, but still I feel sick with many symptoms. I would like to try NDT, can you please advise a reliable source to by Thyroid S online in UK? Thank you.
Alex_N
in
Thyroid UK
3 months ago
Recent GP visit - Thoughts please!
Hi. I'm 60. Last week I just couldn't function, at my whit's end - again. Did another e-consult. Typed out all my history, including being diagnosed with CFS in 2011 and struggling since then with the list of symptoms. Also included my Medichecks thyroid panel results, which have been ignored by the
Hi. I'm 60. Last week I just couldn't function, at my whit's end - again. Did another e-consult. Typed out all my history, including being diagnosed with CFS in 2011 and struggling since then with the list of symptoms. Also included my Medichecks thyroid panel results, which have been ignored by the
Sleepysparrow
in
Thyroid UK
10 months ago
Why do I feel so rundown on ibrance?
Hello, I am a breast cancer survivor, stage 4, her2- , estrogen and progesterone positive.I was on Ibrance and letrozole for around 2 yrs. I was told the pills usually only last 9 months. Almost Depends on the person. Every time I have my labs done my white count and neutrophils were too low.
Hello, I am a breast cancer survivor, stage 4, her2- , estrogen and progesterone positive.I was on Ibrance and letrozole for around 2 yrs. I was told the pills usually only last 9 months. Almost Depends on the person. Every time I have my labs done my white count and neutrophils were too low.
Burtie1
in
SHARE Metastatic Breast Cancer
10 months ago
Is it a waste?
How do you know when you stop making progress? If i keep going to these group therapy sessions and hanging out with my family, but have my head ducking down, into my phone or look at the ground to avoid social interactions....does it still count as a visit? i mean i'm not as bad as im describing i do
How do you know when you stop making progress? If i keep going to these group therapy sessions and hanging out with my family, but have my head ducking down, into my phone or look at the ground to avoid social interactions....does it still count as a visit? i mean i'm not as bad as im describing i do
EricJones
in
Anxiety and Depression Support
3 months ago
Frozen DE treatment cycle different to FET with OE
Hello All, I think I’m missing something obvious but can anyone explain why a frozen DE treatment cycle plans the transfer for day 22-24 while both my FETs have been transferred on day 17 ish? I’m anxious because after a mmc with my last FET, I hope this was a sign of receptivity at 17 day mark and
Hello All, I think I’m missing something obvious but can anyone explain why a frozen DE treatment cycle plans the transfer for day 22-24 while both my FETs have been transferred on day 17 ish? I’m anxious because after a mmc with my last FET, I hope this was a sign of receptivity at 17 day mark and
Kitkat10
in
Fertility Network UK
10 months ago
Testosterone and SHBG puzzle ...
Hello all, I am on HRT including testosterone replacement: what do you think of these results? High SHBG, high testosterone but sub-optimal Free Androgen Index, I was told by a menopause doctor that the index should be around 2.5 to be optimal and that is the most important indicator. I was put on a
Hello all, I am on HRT including testosterone replacement: what do you think of these results? High SHBG, high testosterone but sub-optimal Free Androgen Index, I was told by a menopause doctor that the index should be around 2.5 to be optimal and that is the most important indicator. I was put on a
Clara62
in
Menopause and Perimenopause Support
10 months ago
Compressions
HelloI am 9 weeks post TKR in right knee and I think I might have a problem with my Compressions. I have lower leg Lymphoedema and my left leg was always worst for swelling. Since my knee surgery, my right leg is swelling more. Obviously, this would be partly due to the surgery but when I wear my compression
HelloI am 9 weeks post TKR in right knee and I think I might have a problem with my Compressions. I have lower leg Lymphoedema and my left leg was always worst for swelling. Since my knee surgery, my right leg is swelling more. Obviously, this would be partly due to the surgery but when I wear my compression
AuntyJean15
in
LSN
1 month ago
Major depressive disorder
I was with my ex for 36 years before I foiled for a divorce. We remained close . December 2023 was 1 year for our divorce. He had at least 3 affairs that I proved, I believe he had at least 3 or 4 more that I couldn’t prove. He asked me to move in with him February this year, I did because I thought
I was with my ex for 36 years before I foiled for a divorce. We remained close . December 2023 was 1 year for our divorce. He had at least 3 affairs that I proved, I believe he had at least 3 or 4 more that I couldn’t prove. He asked me to move in with him February this year, I did because I thought
raisin44
in
Anxiety and Depression Support
3 months ago
supplements and lifestyle
Hello guys, I’ve found the advice from you folks to be really helpful since I’ve been on here moaning and groaning so I just wondered if any of you have experienced any measurable improvement in arthritis symptoms using supplements and lifestyle changes? I have just been recommended for TKR surgery
Hello guys, I’ve found the advice from you folks to be really helpful since I’ve been on here moaning and groaning so I just wondered if any of you have experienced any measurable improvement in arthritis symptoms using supplements and lifestyle changes? I have just been recommended for TKR surgery
Wolf68
in
Arthritis Action
1 month ago
failed cryo embryo transfer
Hello I am a 44yo woman. My husband and I underwent ivf cycle earlier this year with own egg. We managed to get 9 eggs and 5 embryo. We had to get them genetically tested and after the long process we have 1 frozen embryo of high quality. So we were very excited about the next step and we started
Hello I am a 44yo woman. My husband and I underwent ivf cycle earlier this year with own egg. We managed to get 9 eggs and 5 embryo. We had to get them genetically tested and after the long process we have 1 frozen embryo of high quality. So we were very excited about the next step and we started
Flora_bah
in
Fertility Network UK
10 months ago
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