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Treatment going forward
Boyfriend is 73 was on AS after TRUS bx with decipher score 3.0. Bx 3+4 after downgrade from JH. Now one year later Saturation Biopsy reports 3+5=8 one core and 4+5=9 two cores between 5 and 20% pattern 5. PSA remains about 3.4. Total of 9/30 positive mostly 3+4=7 20% pattern 4. PSMA PET/CT reports
Boyfriend is 73 was on AS after TRUS bx with decipher score 3.0. Bx 3+4 after downgrade from JH. Now one year later Saturation Biopsy reports 3+5=8 one core and 4+5=9 two cores between 5 and 20% pattern 5. PSA remains about 3.4. Total of 9/30 positive mostly 3+4=7 20% pattern 4. PSMA PET/CT reports
good2go
in
Advanced Prostate Cancer
5 months ago
A potential game-changer for CAR T cell therapy: mutations in cancer engineered to beat cancer
CAR T therapy has been successful in some acute blood cancers. Response rates, however, are considerably lower in CLL and solid tumours, with T cell exhaustion and antigen escape being shared issues. A potentially game-changing advance in solid tumour CAR T technology may therefore be relevant to CAR
CAR T therapy has been successful in some acute blood cancers. Response rates, however, are considerably lower in CLL and solid tumours, with T cell exhaustion and antigen escape being shared issues. A potentially game-changing advance in solid tumour CAR T technology may therefore be relevant to CAR
bennevisplace
in
CLL Support
5 months ago
New to PMR
Hi everyone -- I am new here and have had PMR for about five months now. I can't help wondering if the last Covid vaccine I received may have possibly triggered it, since my symptoms started less than a month after that. (I had already had five previous Covid vaccines.) I was also going through a period
Hi everyone -- I am new here and have had PMR for about five months now. I can't help wondering if the last Covid vaccine I received may have possibly triggered it, since my symptoms started less than a month after that. (I had already had five previous Covid vaccines.) I was also going through a period
Charlotteab
in
PMRGCAuk
8 months ago
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CT Scan normal
hi just a follow up just got the results of my abdominal and pelvic CT scan (with contrast) and all normal, great to get this back and thankful! Symptoms still the same, bloating, upper left pain, gurgling, belching and some nausea. Colonoscopy Thursday but since I had one three years ago GP is expecting
hi just a follow up just got the results of my abdominal and pelvic CT scan (with contrast) and all normal, great to get this back and thankful! Symptoms still the same, bloating, upper left pain, gurgling, belching and some nausea. Colonoscopy Thursday but since I had one three years ago GP is expecting
Dh19
in
IBS Network
4 months ago
managing anxiety
I’ve tested COVID positive. Feeling pretty crap but not as badly as the first couple times. Strangely no one else in the house has caught it. Just me. Initially I was feeling quite panicky about it but I’m managing pretty well. I just hope being quarantined won’t make me slip back into a place of comfort
I’ve tested COVID positive. Feeling pretty crap but not as badly as the first couple times. Strangely no one else in the house has caught it. Just me. Initially I was feeling quite panicky about it but I’m managing pretty well. I just hope being quarantined won’t make me slip back into a place of comfort
MindfulMoment
in
Anxiety and Depression Support
8 months ago
Another Lu-177 solution gets fast tracked: Lu-177-DGUL, secures 'GIFT' designation
"On Monday, the Ministry of Food and Drug Safety (MFDS) designated Lu-177-DGUL as the 11th agent to benefit from its “Global Innovative Products on Fast Track” (GIFT) program, signifying a significant milestone in the quest to offer a beacon of hope for prostate cancer patients who currently have limited
"On Monday, the Ministry of Food and Drug Safety (MFDS) designated Lu-177-DGUL as the 11th agent to benefit from its “Global Innovative Products on Fast Track” (GIFT) program, signifying a significant milestone in the quest to offer a beacon of hope for prostate cancer patients who currently have limited
Maxone73
in
Advanced Prostate Cancer
5 months ago
Covid advice
Has anybody got any advice on how to deal with Covid when on combination therapy? I've just gone down with it for the first time and I'm wondering if I should just continue as normal. Have a pretty high fever and heart rate...wd the T3 exacerbate this?
Has anybody got any advice on how to deal with Covid when on combination therapy? I've just gone down with it for the first time and I'm wondering if I should just continue as normal. Have a pretty high fever and heart rate...wd the T3 exacerbate this?
SilverSavvy
in
Thyroid UK
8 months ago
Covid 19 booster and pneumonia vaccine
Hi has any one had any flares after these vaccines. GP Practice slow so will have to chase. Had the flu one OK had to go to pharmacy as Gp had stopped doing them. Bit concerned about Covid one and RA flares.
Hi has any one had any flares after these vaccines. GP Practice slow so will have to chase. Had the flu one OK had to go to pharmacy as Gp had stopped doing them. Bit concerned about Covid one and RA flares.
welsh12
in
NRAS
8 months ago
covid booster causing PMR flare?
I’d welcome any thoughts/advice please. Had covid booster, 4th, last Friday. Modena same as last year but under its new name, Spikway. Sore arm, very, very tired…done virtually nothing for last two and a half days. Yesterday and today all PMR pains very sore. Bilateral hips, shoulders, neck and biceps
I’d welcome any thoughts/advice please. Had covid booster, 4th, last Friday. Modena same as last year but under its new name, Spikway. Sore arm, very, very tired…done virtually nothing for last two and a half days. Yesterday and today all PMR pains very sore. Bilateral hips, shoulders, neck and biceps
Hulotsholiday
in
PMRGCAuk
8 months ago
Ibrance/Letrozole Fail
Been through the wringer and back over the past month. Scans showed progression. Had bone only mets and now showing inflammation in my lungs. Had more scans and genomic testing for mutations and it turns out I have no mutations that have been studied yet. My oncologist is putting me on Xeloda and says
Been through the wringer and back over the past month. Scans showed progression. Had bone only mets and now showing inflammation in my lungs. Had more scans and genomic testing for mutations and it turns out I have no mutations that have been studied yet. My oncologist is putting me on Xeloda and says
CTGirl1962
in
SHARE Metastatic Breast Cancer
5 months ago
tinnitus after covid
Hi, Has anyone suffered tinnitus for a long time after covid or did it eventually go? If so, how long before it cleared up? Thanks
Hi, Has anyone suffered tinnitus for a long time after covid or did it eventually go? If so, how long before it cleared up? Thanks
Rabb5
in
Tinnitus UK
8 months ago
Isn’t this so true?
In today’s newspaper…….Not getting better During the pandemic, virtually every GP surgery in the land closed its doors as people were told to stay away from the NHS. The reason was purportedly to stop the hospitals overflowing but it effectively put the entire system out of reach for those who did not
In today’s newspaper…….Not getting better During the pandemic, virtually every GP surgery in the land closed its doors as people were told to stay away from the NHS. The reason was purportedly to stop the hospitals overflowing but it effectively put the entire system out of reach for those who did not
AgedCrone
in
NRAS
8 months ago
Covid and under active thyroid
I have just had covid for first time, and it hit me pretty badly, like a bad flu. My glands felt really swollen during it, particularly before, and still do. I'm also so tired. Sleeping a lot. Feel sluggish. Fat for no reason and constipated. This is all the feeling for me that my thyroid is under
I have just had covid for first time, and it hit me pretty badly, like a bad flu. My glands felt really swollen during it, particularly before, and still do. I'm also so tired. Sleeping a lot. Feel sluggish. Fat for no reason and constipated. This is all the feeling for me that my thyroid is under
Billy2023
in
Thyroid UK
8 months ago
funny turn
Hello all, About 18 months ago I had a stent fitted - didn’t have a heart attack - but every so often I have chest discomfort, like now. I vape quite a lot (ex-smoker). I’m pretty sure that my current bout of discomfort isn’t heart related but my mind is going bonkers and now I don’t know whether I
Hello all, About 18 months ago I had a stent fitted - didn’t have a heart attack - but every so often I have chest discomfort, like now. I vape quite a lot (ex-smoker). I’m pretty sure that my current bout of discomfort isn’t heart related but my mind is going bonkers and now I don’t know whether I
MrBoring
in
British Heart Foundation
10 months ago
Mucus back again
Hi all. As some may remember I suffer from ongoing mucus discharge from rectum. I had a colonoscopy done year and 3/4 ago and clear. All tests.I went gluten dairy free. It worked and did stop it happening everyday but for some weird reason past 3 weeks I've had all my symtoms back again with vengeance
Hi all. As some may remember I suffer from ongoing mucus discharge from rectum. I had a colonoscopy done year and 3/4 ago and clear. All tests.I went gluten dairy free. It worked and did stop it happening everyday but for some weird reason past 3 weeks I've had all my symtoms back again with vengeance
mal444
in
IBS Network
4 months ago
liver concerns
I had clear cell ovarian cancer and had debulking surgery and hysterectomy a year ago. I recently had sudden right side and back pain and had a scan with blood work. Everything came out ok except my liver numbers (ast and alt) were super high. Could this indicate the start of a reoccurrence? Has
I had clear cell ovarian cancer and had debulking surgery and hysterectomy a year ago. I recently had sudden right side and back pain and had a scan with blood work. Everything came out ok except my liver numbers (ast and alt) were super high. Could this indicate the start of a reoccurrence? Has
Marieck
in
My Ovacome
5 months ago
low hemoglobin
my dad has a hemoglobin of 10. He has been dizzy, and had a rash(Unclear if the two are related- - PCP said possibly ). Also low appetite. Just completed radiation Jan 3 and started the Lupron end of November. Radiation was done to prostate and to met on hip bone. Anyone have insight into what
my dad has a hemoglobin of 10. He has been dizzy, and had a rash(Unclear if the two are related- - PCP said possibly ). Also low appetite. Just completed radiation Jan 3 and started the Lupron end of November. Radiation was done to prostate and to met on hip bone. Anyone have insight into what
alysona828
in
Advanced Prostate Cancer
5 months ago
Tumor Lysis Syndrome
As a result of developing tumor lysis syndrome 2021 while in the hospital (receiving Ven,) my kidneys were affected. This week I will have a kidney stent removed and possibly replaced. Has anyone had a similar experience? The kidney stents will be done in a hospital.
As a result of developing tumor lysis syndrome 2021 while in the hospital (receiving Ven,) my kidneys were affected. This week I will have a kidney stent removed and possibly replaced. Has anyone had a similar experience? The kidney stents will be done in a hospital.
bayside64
in
CLL Support
10 months ago
Hello
Hi everyone, I've been Stage IV mbc since December 2019, on Ibrance / Letrozole but now facing a change. Those drugs (with some off label drugs and naturopathic treatments/supplements) kept me stable for nearly 4 years. Now some update on my left femur, sternum and new tumors in my liver. Curious
Hi everyone, I've been Stage IV mbc since December 2019, on Ibrance / Letrozole but now facing a change. Those drugs (with some off label drugs and naturopathic treatments/supplements) kept me stable for nearly 4 years. Now some update on my left femur, sternum and new tumors in my liver. Curious
Bella_mum
in
SHARE Metastatic Breast Cancer
5 months ago
clinical trial vyd222 monoclonal AB against covid update science 37
thought i'd give an update on my experience with this study. i got my first infusion on oct 17th and had no ill effects other than my blood pressure getting super high. but i think that was from the last minute fumbles in planning thru science 37. my infusion medicine was supposed to arrive the afternoon
thought i'd give an update on my experience with this study. i got my first infusion on oct 17th and had no ill effects other than my blood pressure getting super high. but i think that was from the last minute fumbles in planning thru science 37. my infusion medicine was supposed to arrive the afternoon
bachplayer13
in
CLL Support
8 months ago
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