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ASCO 2023: AI-Derived Digital Pathology Biomarker Predicts Benefit of Long-Term ADT with Radiotherapy in Localized High-Risk Prostate Cancer
https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144902-asco-2023-development-and-validation-of-an-ai-derived-digital-pathology-based-biomarker-to-predict-benefit-of-long-term-androgen-deprivation-therapy-with-radiotherapy-in-men-with-localized-high-risk-prostate-cancer-across-multiple-phase-iii-nrg-rtog-trials.html
https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144902-asco-2023-development-and-validation-of-an-ai-derived-digital-pathology-based-biomarker-to-predict-benefit-of-long-term-androgen-deprivation-therapy-with-radiotherapy-in-men-with-localized-high-risk-prostate-cancer-across-multiple-phase-iii-nrg-rtog-trials.html
zeitgeistxx
in
Advanced Prostate Cancer
6 months ago
Mini maze update.
Apologies I know I promised to post updates and haven't. I had my mini maze surgery back in September with the wonderful Mr Hunter on the NHS. I've been in NSR ever since which is amazing as I had moved to persistant Afib and I felt pretty awful all the time before surgery. I am soooo grateful to Mr
Apologies I know I promised to post updates and haven't. I had my mini maze surgery back in September with the wonderful Mr Hunter on the NHS. I've been in NSR ever since which is amazing as I had moved to persistant Afib and I felt pretty awful all the time before surgery. I am soooo grateful to Mr
waveylines
in
Atrial Fibrillation Support
6 months ago
PSA 6 months after RT
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
janebob99
in
Prostate Cancer Network
6 months ago
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Lupron Injection denied by Medicare Advantage PPO plan
My husband will need Lupron injections monthly x4. Two before starting radiation, and 2 during radiation treatment. The insurance, Medicare Advantage PPO, denied it. Anyone successfully appealed the denial? Any suggestions from the group? I checked and Medicare part D covers Lupron for the treatment
My husband will need Lupron injections monthly x4. Two before starting radiation, and 2 during radiation treatment. The insurance, Medicare Advantage PPO, denied it. Anyone successfully appealed the denial? Any suggestions from the group? I checked and Medicare part D covers Lupron for the treatment
Inquisitive_one
in
Advanced Prostate Cancer
6 months ago
Discontinue all antioxidant supplements on early signs of biochemical recurrence?
The latest literature appears to indicate a PSA as low as 0.03, regardless of the multi-result dynamics is a reliable very early confirmation of biochemical recurrence. Maybe it's arguable some rare cases may "slip through" and stabilize without further treatment but data from the latest studies is
The latest literature appears to indicate a PSA as low as 0.03, regardless of the multi-result dynamics is a reliable very early confirmation of biochemical recurrence. Maybe it's arguable some rare cases may "slip through" and stabilize without further treatment but data from the latest studies is
jazj
in
Advanced Prostate Cancer
6 months ago
Are Lymph nodes a filter?
Do lymph nodes simply act as a temporary filter to prevent cancer from spreading too far? I was curious about this because I have 4th stage prostate cancer, and my Lymph had swelled to the size of a golfball. When I took the ADT, my PSA went from 1000, down to 6, and all evidence of cancer disappeared
Do lymph nodes simply act as a temporary filter to prevent cancer from spreading too far? I was curious about this because I have 4th stage prostate cancer, and my Lymph had swelled to the size of a golfball. When I took the ADT, my PSA went from 1000, down to 6, and all evidence of cancer disappeared
Aldo62
in
Advanced Prostate Cancer
6 months ago
My decision on Radiotherapy -v- Prostatectomy
I hope this story might be useful to others. I'm based in the UK and had a PSA of 12.7 from a test in June 2023. That led to an MRI in August with a PI-RADS of 5 with irregularity on the front of the prostate. I eventually had a biopsy at the end of September after 3 cancellations (this was through the
I hope this story might be useful to others. I'm based in the UK and had a PSA of 12.7 from a test in June 2023. That led to an MRI in August with a PI-RADS of 5 with irregularity on the front of the prostate. I eventually had a biopsy at the end of September after 3 cancellations (this was through the
MarkS
in
Prostate Cancer Network
6 months ago
1 Year out Radiation treatment
2018, Gleason 9, family history, RP surgery. Not clear margin. PSA undetectable three years, then back knocking at the door, (.17 PSA rise 2022). BCR! PSMA scan clear. 35 IMRT Radiation treatments to surgery prostate bed, 6 months on Lupron. See my wonderful Radiation Onocolgist on Monday, Dr. Hung,
2018, Gleason 9, family history, RP surgery. Not clear margin. PSA undetectable three years, then back knocking at the door, (.17 PSA rise 2022). BCR! PSMA scan clear. 35 IMRT Radiation treatments to surgery prostate bed, 6 months on Lupron. See my wonderful Radiation Onocolgist on Monday, Dr. Hung,
rickyfish56
in
Advanced Prostate Cancer
6 months ago
Health Update
So I had the mammogram and ultrasound. Imaging shows a 2cm lump stuck to the breast. The consultant says it is cancer and will be confirmed by the biopsy. Lucky it's caught early and doesn't look like it's spread to the lymph nodes. The plan is breast conservation therapy. A lumpectomy and radiotherapy
So I had the mammogram and ultrasound. Imaging shows a 2cm lump stuck to the breast. The consultant says it is cancer and will be confirmed by the biopsy. Lucky it's caught early and doesn't look like it's spread to the lymph nodes. The plan is breast conservation therapy. A lumpectomy and radiotherapy
LindaLittleBear
in
British Heart Foundation
6 months ago
Pre-CRPC Supplements/Drugs - Potential Risks vs Rewards?
With some substances there could be a "tipping" point depending on the substance, the dosage and the patient's stage of cancer where the substance may have a higher chance of having a negative effect instead of positive. It usually relates to ROS levels. Adequate levels of ROS are important for cancer
With some substances there could be a "tipping" point depending on the substance, the dosage and the patient's stage of cancer where the substance may have a higher chance of having a negative effect instead of positive. It usually relates to ROS levels. Adequate levels of ROS are important for cancer
jazj
in
Advanced Prostate Cancer
6 months ago
PMR / Prednisone
I personally am critical of going up or down on prednisone dosage. I was diagnosed with PMR about 4 years ago and have had bouts of low and high doses in the intervening years with very little impact. I dreaded having to be on steroids for a long period with all their scary side affects! I am now off
I personally am critical of going up or down on prednisone dosage. I was diagnosed with PMR about 4 years ago and have had bouts of low and high doses in the intervening years with very little impact. I dreaded having to be on steroids for a long period with all their scary side affects! I am now off
GucciPaddy
in
PMRGCAuk
6 months ago
Rough few days
This past week has been hard on me. Thursday I was scheduled for the last of 5 radiation treatments to my lower back, and to begin Taxol treatments, at two different cancer centers. My blood pressure was so low, I was sent to an "urgent care" center and then from there by ambulance to the ER. All
This past week has been hard on me. Thursday I was scheduled for the last of 5 radiation treatments to my lower back, and to begin Taxol treatments, at two different cancer centers. My blood pressure was so low, I was sent to an "urgent care" center and then from there by ambulance to the ER. All
PJBinMI
in
SHARE Metastatic Breast Cancer
6 months ago
A New complication!
My husband was diagnosed with PC in 2013, PSA 18, Gleason 4+3. Possible small met on pelvis. This was treated with radiotherapy. On Decapeptyl 6 monthly injections, and over the years, Xgeva, Xtandi and for the past couple of years, Erleada. Unfortunately, due to stomach surgery 2 years ago, where
My husband was diagnosed with PC in 2013, PSA 18, Gleason 4+3. Possible small met on pelvis. This was treated with radiotherapy. On Decapeptyl 6 monthly injections, and over the years, Xgeva, Xtandi and for the past couple of years, Erleada. Unfortunately, due to stomach surgery 2 years ago, where
Hidden
in
Advanced Prostate Cancer
6 months ago
Blood in Urine
Hi fellow fighters Had blood in my urine the last 10 days. Hoped it was a UTI but a course of antibiotics has failed. I had a bladder neck incision last June to help urinary flow. The urologist saw a suspicious patch and a biopsy confirmed it my prostate cancer has spread to my bladder. I’m hoping
Hi fellow fighters Had blood in my urine the last 10 days. Hoped it was a UTI but a course of antibiotics has failed. I had a bladder neck incision last June to help urinary flow. The urologist saw a suspicious patch and a biopsy confirmed it my prostate cancer has spread to my bladder. I’m hoping
Tonyliv
in
Advanced Prostate Cancer
6 months ago
Thanks and hope to all
No questions …just wanted to thank everyone for all your input and support …especially during the holidays. Had my Christmas radiation treatment yesterday and 7 of 15 linac dose today.. Brachytherapy prior with ADT for the last 7 months. Things seem to be going as smoothly as it sometimes does. Appreciate
No questions …just wanted to thank everyone for all your input and support …especially during the holidays. Had my Christmas radiation treatment yesterday and 7 of 15 linac dose today.. Brachytherapy prior with ADT for the last 7 months. Things seem to be going as smoothly as it sometimes does. Appreciate
Yokohama2023
in
Advanced Prostate Cancer
6 months ago
Diagnosed with all the arrhythmias and a 40% ejection fraction and I'm a little confused about what's to come...
Hi, So (I'll try and keep a long story short) 8 years ago I was diagnosed with breast cancer, I had chemo, radiotherapy and surgery. 3 years ago I gave birth to my son and (in lock down) I'd walk for miles and miles with him in a sling. Around 2 years ago, while pregnant with my daughter, I got tired
Hi, So (I'll try and keep a long story short) 8 years ago I was diagnosed with breast cancer, I had chemo, radiotherapy and surgery. 3 years ago I gave birth to my son and (in lock down) I'd walk for miles and miles with him in a sling. Around 2 years ago, while pregnant with my daughter, I got tired
Alana84
in
British Heart Foundation
6 months ago
Is nmCRPC potentially curable?
I would appreciate any input on this. I searched the internet and found this article from Fred Saad: Treatment of nonmetastatic castration-resistant prostate cancer: focus on second-generation androgen receptor inhibitors https://www.nature.com/articles/s41391-020-00310-3 I couldn't find anything
I would appreciate any input on this. I searched the internet and found this article from Fred Saad: Treatment of nonmetastatic castration-resistant prostate cancer: focus on second-generation androgen receptor inhibitors https://www.nature.com/articles/s41391-020-00310-3 I couldn't find anything
Seasid
in
Advanced Prostate Cancer
6 months ago
Very Happy Bunny 🐰
I had my appointment at the Late Side Effects clinic on Tuesday 19th December. I met the senior radiographer an oncologist and a nurse all of whom were very helpful and kind. They had all my notes dating back from my cancer treatment in 2015 to date including all the hospitals and consultants I’ve seen
I had my appointment at the Late Side Effects clinic on Tuesday 19th December. I met the senior radiographer an oncologist and a nurse all of whom were very helpful and kind. They had all my notes dating back from my cancer treatment in 2015 to date including all the hospitals and consultants I’ve seen
Hidden
in
Pelvic Radiation Disease Association
6 months ago
GBM and Keto Diet - Urgent
My brother was diagnosed with GBM (grade IV) in May 2023. I wonder, please, if any of you know about the Keto Diet and how effective it might be in treating GBM. He has had CV (Awake Craniotomy), followed by chemotherapy and radiation therapy. Thank you
My brother was diagnosed with GBM (grade IV) in May 2023. I wonder, please, if any of you know about the Keto Diet and how effective it might be in treating GBM. He has had CV (Awake Craniotomy), followed by chemotherapy and radiation therapy. Thank you
Hermanito
in
Glioblastoma Support
6 months ago
Rickyfish56 "Introduction"
Reviewed my "Bio" and it said I needed to "introduce" myself? Mostly just read postings and try to gather information. But, here is my " introduction", family history of Prostate cancer, Dad diagnosed at 59, removed prostate old fashion slice and dice, never regained any sexual function, but alive today
Reviewed my "Bio" and it said I needed to "introduce" myself? Mostly just read postings and try to gather information. But, here is my " introduction", family history of Prostate cancer, Dad diagnosed at 59, removed prostate old fashion slice and dice, never regained any sexual function, but alive today
rickyfish56
in
Advanced Prostate Cancer
6 months ago
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