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Ibrutinib Treatment Shows Efficacy and Tolerability in Heavily Treated CLL Patients Following Allogeneic Stem Cell Transplant
You have to admire Pharmacyclics advertising capability. Here they are showing how effective Ibrutinib (Imbruvica) is on a tough to treat bunch of CLL patients. [i]"These patients had a median of five prior therapies and 63% were high-risk del 17p CLL patients. The estimated median progression-free
You have to admire Pharmacyclics advertising capability. Here they are showing how effective Ibrutinib (Imbruvica) is on a tough to treat bunch of CLL patients. [i]"These patients had a median of five prior therapies and 63% were high-risk del 17p CLL patients. The estimated median progression-free
AussieNeil
Partner
in
CLL Support
9 years ago
Next Generation Sequencing Panel Focus::CLL (TM) Selected for Use in Global Clinical Trial
[i]"Our highly focused and custom next generation sequencing panel for CLL affords excellent depth of detection of variants in genes of high prognostic value in CLL patients," said Jane Houldsworth, Ph.D., Vice President of Research and Development at CGI. "For the first time, comprehensive, robust mutation
[i]"Our highly focused and custom next generation sequencing panel for CLL affords excellent depth of detection of variants in genes of high prognostic value in CLL patients," said Jane Houldsworth, Ph.D., Vice President of Research and Development at CGI. "For the first time, comprehensive, robust mutation
AussieNeil
Partner
in
CLL Support
9 years ago
How are you actually feeling?
Dear all, I'm sure that, like me, many of us have hospital/consultant/doctors appointments-enough to fill the whole house eighteen million times over, well it seems like it anyway! The main question, that is not always asked is, how do you actually feel? Are there times when, despite 'bad' results
Dear all, I'm sure that, like me, many of us have hospital/consultant/doctors appointments-enough to fill the whole house eighteen million times over, well it seems like it anyway! The main question, that is not always asked is, how do you actually feel? Are there times when, despite 'bad' results
AndrewT
in
Vasculitis UK
9 years ago
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Transplant
Can anyone please let me know that the older you are you are less likely to receive a kidney transplant as I have read that after a certain age you go on a points system and are judged on age ,health e.t.c, I am 62 and the thought that I might not get a transplant because of my age really depresses me
Can anyone please let me know that the older you are you are less likely to receive a kidney transplant as I have read that after a certain age you go on a points system and are judged on age ,health e.t.c, I am 62 and the thought that I might not get a transplant because of my age really depresses me
catwoman0005
in
Kidney Transplant Patient Support
9 years ago
chlorambucil
Hi everyone, I think that chlorambucil was mainly used for CLL treatment before FRC was formulated. Today, chlorambucil is sometimes used instead of FCR. Is this the reason why chlorambucil is not so strong drug and so good for old patients? Miee
Hi everyone, I think that chlorambucil was mainly used for CLL treatment before FRC was formulated. Today, chlorambucil is sometimes used instead of FCR. Is this the reason why chlorambucil is not so strong drug and so good for old patients? Miee
Miee
in
CLL Support
9 years ago
Doubled wbc count good or bad?
So my father in laws latest test results came back after a week of chlorambucil... Wbc down to 51 (from 100), platelets down to 10 (from 40) at diagnosis ... He claims he read somewhere that doubling wbc count is a good prognosis... My pc is down with a virus infestation, so I was wondering if anyone
So my father in laws latest test results came back after a week of chlorambucil... Wbc down to 51 (from 100), platelets down to 10 (from 40) at diagnosis ... He claims he read somewhere that doubling wbc count is a good prognosis... My pc is down with a virus infestation, so I was wondering if anyone
marcelarr
in
CLL Support
9 years ago
Why the causes of cancer are more than just random ‘bad luck’
A month back, Johns Hopkins University researchers made big news with their conclusion from the analysis of scientific papers that in two thirds of cases, human cancers are due to randomly generated DNA errors, which I posted about here: https://healthunlocked.com/cllsupport/posts/131417190/it-is-most-likely-just-bad-luck-that-we-got-cll
A month back, Johns Hopkins University researchers made big news with their conclusion from the analysis of scientific papers that in two thirds of cases, human cancers are due to randomly generated DNA errors, which I posted about here: https://healthunlocked.com/cllsupport/posts/131417190/it-is-most-likely-just-bad-luck-that-we-got-cll
AussieNeil
Partner
in
CLL Support
9 years ago
Aussies - Availability of blood cancer drugs – Have Your Say
CLL patients in Australia have an opportunity to inform a Senate inquiry regarding the 'availability' of blood cancer drugs. This is rather timely considering the last two CLL drug proposals were rejected and we are trailing badly behind the US, UK and even Canada! From the Leukaemia Foundation: [i
CLL patients in Australia have an opportunity to inform a Senate inquiry regarding the 'availability' of blood cancer drugs. This is rather timely considering the last two CLL drug proposals were rejected and we are trailing badly behind the US, UK and even Canada! From the Leukaemia Foundation: [i
AussieNeil
Partner
in
CLL Support
9 years ago
Spot the snake oil: telling good cancer research from bad
Nial Wheate, Senior Lecturer in Pharmaceutical Chemistry at University of Sydney provides a quick but very useful guide that we can use to assess whether proposed treatments are likely to do us any good: http://theconversation.com/spot-the-snake-oil-telling-good-cancer-research-from-bad-36344 I'm fairly
Nial Wheate, Senior Lecturer in Pharmaceutical Chemistry at University of Sydney provides a quick but very useful guide that we can use to assess whether proposed treatments are likely to do us any good: http://theconversation.com/spot-the-snake-oil-telling-good-cancer-research-from-bad-36344 I'm fairly
AussieNeil
Partner
in
CLL Support
9 years ago
Hello folks,
I went for my four month check up today and found my white blood count was worse- has doubled in less than a year. Treatment therefore is needed soon. I have been offered a clinical trial, of Idelalisib (or placebo...) combined with Bendamustine and Rituximab. It seems like the way to go, but Iwould
I went for my four month check up today and found my white blood count was worse- has doubled in less than a year. Treatment therefore is needed soon. I have been offered a clinical trial, of Idelalisib (or placebo...) combined with Bendamustine and Rituximab. It seems like the way to go, but Iwould
romarin
in
CLL Support
9 years ago
Chronic fatigue syndrome???
I saw a story on the news tonight that doctors have "legalized" chronic fatigue syndrome and recognized it as a disease called Systemic Exertion Intolerance Disease. But I wonder. They listed the symptoms: fatigue not relieved by rest, brain fog, feeling better when lying down. Sounds a lot like
I saw a story on the news tonight that doctors have "legalized" chronic fatigue syndrome and recognized it as a disease called Systemic Exertion Intolerance Disease. But I wonder. They listed the symptoms: fatigue not relieved by rest, brain fog, feeling better when lying down. Sounds a lot like
teenarocks
in
Thyroid UK
9 years ago
What value screening for CLL?
We are well aware of public health cancer screening programs and I'm certain I'm not the only one here wondering if screening for CLL would help our community. Here's a fairly clear explanation by academics Katy Bell, Alexandra Barratt and Andrew Hayen from New South Wales, Australia, of situations
We are well aware of public health cancer screening programs and I'm certain I'm not the only one here wondering if screening for CLL would help our community. Here's a fairly clear explanation by academics Katy Bell, Alexandra Barratt and Andrew Hayen from New South Wales, Australia, of situations
AussieNeil
Partner
in
CLL Support
9 years ago
How chronic fatigue can effect the brain.
Scientists at the Stanford University School of Medicine have found specific changes in the brains, particularly the white matter, of patients with chronic fatigue syndrome, or CFS. Patients with CFS have dealt with a number of misunderstandings due to their condition, from people who think the affected
Scientists at the Stanford University School of Medicine have found specific changes in the brains, particularly the white matter, of patients with chronic fatigue syndrome, or CFS. Patients with CFS have dealt with a number of misunderstandings due to their condition, from people who think the affected
cc120
in
Thyroid UK
9 years ago
diane 63
Hi every one i have copd i realized i had it in 2007 i stopped smoking ? i have a intolerance to every thing for copd i take inhalers Seratide , Atrovent , Sabutamol. my G P has just changed my Seratide to flutiform burned my mouth as soon as i used it , And that
Hi every one i have copd i realized i had it in 2007 i stopped smoking ? i have a intolerance to every thing for copd i take inhalers Seratide , Atrovent , Sabutamol. my G P has just changed my Seratide to flutiform burned my mouth as soon as i used it , And that
dianewinter63
in
Lung Conditions Community Forum
9 years ago
Rats and Little Mouses...
There is a little animal under the sitting room windowsill...inside...not outside and he or she chews away happily half the night...I sleep on the settee as you know and the settee is right under the window, so in the middle of night, when it's fairly dark and reasonably quiet, that chewing sounds quite
There is a little animal under the sitting room windowsill...inside...not outside and he or she chews away happily half the night...I sleep on the settee as you know and the settee is right under the window, so in the middle of night, when it's fairly dark and reasonably quiet, that chewing sounds quite
Hidden
in
Lung Conditions Community Forum
9 years ago
Writing Stories...
I do find writing stories or articles easy enough...most especially when the gist of them come from personal memories where there is no need to be precise or exact over names and dates or places. Those I find more difficult are those which need to be factual...for instance, I began yesterday to write
I do find writing stories or articles easy enough...most especially when the gist of them come from personal memories where there is no need to be precise or exact over names and dates or places. Those I find more difficult are those which need to be factual...for instance, I began yesterday to write
Hidden
in
Lung Conditions Community Forum
9 years ago
New improved inhaler on the horizon
September 2014: http://us.boehringer-ingelheim.com/news_events/press_releases/press_release_archive/2014/09-08-14-boehringer-ingelheim-presents-pivotal-phase-iii-data-investigational-fixed-dose-combination-tiotropium-olodaterol-copd.html Quote: '. . . Once-daily tiotropium + olodaterol FDC [Fixed Dose
September 2014: http://us.boehringer-ingelheim.com/news_events/press_releases/press_release_archive/2014/09-08-14-boehringer-ingelheim-presents-pivotal-phase-iii-data-investigational-fixed-dose-combination-tiotropium-olodaterol-copd.html Quote: '. . . Once-daily tiotropium + olodaterol FDC [Fixed Dose
stilltruckin
in
Lung Conditions Community Forum
9 years ago
Gene mutation and inflammatory GI tract disease
We need to be assessing CLL and its effects on our health in a broad context. This article quite fascinating in possibly linking a frequent gene mutation in CLL to some of the community's reported GI tract maladies. http://tinyurl.com/ocy5vn6 Al Janski had posted on the microbiota and its influence
We need to be assessing CLL and its effects on our health in a broad context. This article quite fascinating in possibly linking a frequent gene mutation in CLL to some of the community's reported GI tract maladies. http://tinyurl.com/ocy5vn6 Al Janski had posted on the microbiota and its influence
ThreeWs
in
CLL Support
9 years ago
I am sanjay Shah and my fbs is 200 And ppbs is 300 I am on medicine in morning 22 units of mixtard 30 insulin before and glycifage m2 -1
And istamate before meal and glycifage + mixtard 30 20 unit before dinner. What should I do to normalise my diabetes. In since six year my diabetes Never become normal. Pl. Suggest
And istamate before meal and glycifage + mixtard 30 20 unit before dinner. What should I do to normalise my diabetes. In since six year my diabetes Never become normal. Pl. Suggest
sanjaysha
in
Diabetes India
9 years ago
Health Effects of Marijuana Legalization in Colorado
Several US states, including Colorado, have recently legalised marijuana. Psychiatry Advisor have highlighted an opinion piece published in JAMA Psychiatry that looks at the expected and unexpected health implications for those using the drug: http://www.psychiatryadvisor.com/legal-marijuana-health-effects
Several US states, including Colorado, have recently legalised marijuana. Psychiatry Advisor have highlighted an opinion piece published in JAMA Psychiatry that looks at the expected and unexpected health implications for those using the drug: http://www.psychiatryadvisor.com/legal-marijuana-health-effects
AussieNeil
Partner
in
CLL Support
9 years ago
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