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Prostate Cancer PSA is detectible again
I am a 57-year-old male. My prostate cancer was diagnosed in 2019, and I had a radical prostatectomy at Vanderbilt. In early 2023, my PSA went up to 0.12. I underwent a PET scan, which returned negative. However, an MRI revealed a small area at the prostatectomy suture site. On October 27, 2023, I completed
I am a 57-year-old male. My prostate cancer was diagnosed in 2019, and I had a radical prostatectomy at Vanderbilt. In early 2023, my PSA went up to 0.12. I underwent a PET scan, which returned negative. However, an MRI revealed a small area at the prostatectomy suture site. On October 27, 2023, I completed
DLetterman
in
Prostate Cancer Network
3 months ago
change of therapy
Rarely post, but try to read as often as I can. Hope to get the advice based on your experience. Based on my scans it looks that I have progression. New bone mets. TM are trending higher, but not significant. No mutations. I’m in US. I’m on palbo+letrozole for almost 4 years, but of course not
Rarely post, but try to read as often as I can. Hope to get the advice based on your experience. Based on my scans it looks that I have progression. New bone mets. TM are trending higher, but not significant. No mutations. I’m in US. I’m on palbo+letrozole for almost 4 years, but of course not
Tolife_18
in
SHARE Metastatic Breast Cancer
3 months ago
Sacituzumab govitecan, an anti-Trop-2 antibody-drug conjugate, for treating cerebral metastasized castration-resistant prostate cancer.
Improved survival rates have been observed in castration-resistant prostate cancer (CRPC) due to advancements in treatment options. However, individuals with brain metastases still have limited therapeutic options and an unfavorable prognosis. Therefore, there is an urgent need to explore new therapeutic
Improved survival rates have been observed in castration-resistant prostate cancer (CRPC) due to advancements in treatment options. However, individuals with brain metastases still have limited therapeutic options and an unfavorable prognosis. Therefore, there is an urgent need to explore new therapeutic
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
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Appointment with Provenge doctor
Finally found a local doctor to talk with about Provenge. Appointment is early Monday morning. For anyone familiar with Provenge, can you suggest questions for me to ask? My PSA has been rising after six years on Lupron only. 1.92 in June, all-time lows .5 3/2021.
Finally found a local doctor to talk with about Provenge. Appointment is early Monday morning. For anyone familiar with Provenge, can you suggest questions for me to ask? My PSA has been rising after six years on Lupron only. 1.92 in June, all-time lows .5 3/2021.
dhccpa
in
Advanced Prostate Cancer
3 months ago
Stage 3 Breast Cancer
I discovered a lump in my breast, had an MRI, biopsy, several scans and was diagnosed with stage 3C breast cancer. Started Anastrazole and Ibrance. After 2 weeks was taken off the Ibrance because wbc dropped too low. After 2 weeks off my wbc was still too low so am hoping to start a lower dose of
I discovered a lump in my breast, had an MRI, biopsy, several scans and was diagnosed with stage 3C breast cancer. Started Anastrazole and Ibrance. After 2 weeks was taken off the Ibrance because wbc dropped too low. After 2 weeks off my wbc was still too low so am hoping to start a lower dose of
catfreddie
in
SHARE Breast Cancer Support
3 months ago
Slight PSA rise and MO discontinuing ADT due to fatigue
Father, 86, Stage 4A prostate cancer has been treated under STAMPEDE Protocol since November 2022 including prostate + whole pelvic radiation completed March 2023 (history in bio). Had appointment with MO today - initial plan was for this to be last shot of Lupron while Zytiga would be continued for
Father, 86, Stage 4A prostate cancer has been treated under STAMPEDE Protocol since November 2022 including prostate + whole pelvic radiation completed March 2023 (history in bio). Had appointment with MO today - initial plan was for this to be last shot of Lupron while Zytiga would be continued for
Superbfloor
in
Advanced Prostate Cancer
3 months ago
Patient Stress and Anxiety Test
Ive been off of Abiraterone over 2 months now due to Afib. Was on it 21 months Only on Lupron starting 3rd year. Did full pelvic radiation. I treated myself to a Us PSA test, and Im at <0.02. MO agreed to let me stay off Abi, and retest in 3 months, Fingers crossed.
Ive been off of Abiraterone over 2 months now due to Afib. Was on it 21 months Only on Lupron starting 3rd year. Did full pelvic radiation. I treated myself to a Us PSA test, and Im at <0.02. MO agreed to let me stay off Abi, and retest in 3 months, Fingers crossed.
Still_in_shock
in
Advanced Prostate Cancer
3 months ago
looking for input - RIsing PSA with Negative PSMA Pet scan
diagnosed in 2020 with Oligometastatic prostate cancer (1 spot detected on right ischium (hip)). Had prostate removed via surgery, did 39 radiation treatments to hip and prostate bed and took Lupron and Erleada . Stopped the hormone therapy in July 2022 (psa undetectable for 2 yrs). My psa in 2024
diagnosed in 2020 with Oligometastatic prostate cancer (1 spot detected on right ischium (hip)). Had prostate removed via surgery, did 39 radiation treatments to hip and prostate bed and took Lupron and Erleada . Stopped the hormone therapy in July 2022 (psa undetectable for 2 yrs). My psa in 2024
ND1988
in
Advanced Prostate Cancer
3 months ago
Niclosamide-based metabolic anticancer drug's first clinical trial will target CRPC
Yes, they will start from castration resistant prostate cancer patients https://www.biospace.com/article/releases/adm-korea-announces-niclosamide-based-metabolic-anticancer-drug-s-first-clinical-trial-target-as-prostate-cancer-patients-resistant-to-hormone-therapy-/ EDIT: for some reason that link
Yes, they will start from castration resistant prostate cancer patients https://www.biospace.com/article/releases/adm-korea-announces-niclosamide-based-metabolic-anticancer-drug-s-first-clinical-trial-target-as-prostate-cancer-patients-resistant-to-hormone-therapy-/ EDIT: for some reason that link
Maxone73
in
Advanced Prostate Cancer
3 months ago
Minor change in psa - reason to be concern?
Hi, My dad just got an update on his PSA #. 3 weeks ago his PSA was 0.37, our family went on vacation, and he just got back and had his blood work done again. All enzymes normal, but PSA ticked up slightly to 0.47. Is this concerning at all? I thought PSA was suppose to trend to undetectable levels
Hi, My dad just got an update on his PSA #. 3 weeks ago his PSA was 0.37, our family went on vacation, and he just got back and had his blood work done again. All enzymes normal, but PSA ticked up slightly to 0.47. Is this concerning at all? I thought PSA was suppose to trend to undetectable levels
Cafu6
in
Advanced Prostate Cancer
3 months ago
UBX-103: potentially first in class AR degrader
keep an eye on this (help me I am running out of eyes!) an AR degrader really aims at destroying AR receptors, the idea is that when a second generation arsi is no longer working (Enza, Daro,…) you still have the option to use this new drug for metastatic prostate cancer https://www.biospace.com/article
keep an eye on this (help me I am running out of eyes!) an AR degrader really aims at destroying AR receptors, the idea is that when a second generation arsi is no longer working (Enza, Daro,…) you still have the option to use this new drug for metastatic prostate cancer https://www.biospace.com/article
Maxone73
in
Advanced Prostate Cancer
3 months ago
Introduction and asking for help interpreting latest scan results and thoughts on future treatment plan please.
Long time reader but first time posting.. I have just received my latest PSMA PET-CT scan results and would like some help interpreting the results and gain your thoughts about situation and treatment plan. My overall history: After slowly rising PSA scores to a relatively low peak of 6.1 at 59 years
Long time reader but first time posting.. I have just received my latest PSMA PET-CT scan results and would like some help interpreting the results and gain your thoughts about situation and treatment plan. My overall history: After slowly rising PSA scores to a relatively low peak of 6.1 at 59 years
APCFighter
in
Advanced Prostate Cancer
3 months ago
Results on 75mcg T4
Dear members, I am lost,I need help. I have hashi and hypo. 6 weeks ago I switched medications from 50mcg for 7 days Tirosint to 75mcg Tirosint for 5 days and 2 days 50 mcg. My results on 50mcg/7 days TSH 0.036 (0.27-4.20) FT3 3.75 ( 3.1-6.8) FT4 16.80 (12-22) My results on 75mcg/5 days/50mcg 2 days
Dear members, I am lost,I need help. I have hashi and hypo. 6 weeks ago I switched medications from 50mcg for 7 days Tirosint to 75mcg Tirosint for 5 days and 2 days 50 mcg. My results on 50mcg/7 days TSH 0.036 (0.27-4.20) FT3 3.75 ( 3.1-6.8) FT4 16.80 (12-22) My results on 75mcg/5 days/50mcg 2 days
MartinaM
in
Thyroid UK
3 months ago
Has anyone heard any updated info on APP-111?
This story from 2016 sounded promising for advanced PCa… https://www.drugtargetreview.com/news/6903/aspen-park-acquires-rights-to-castration-resistant-prostate-cancer-drug/
This story from 2016 sounded promising for advanced PCa… https://www.drugtargetreview.com/news/6903/aspen-park-acquires-rights-to-castration-resistant-prostate-cancer-drug/
CousinGrandpa
in
Advanced Prostate Cancer
3 months ago
Psyllium Husk
Hi, had another flare up yesterday, after being reasonably ok for the last 3 weeks = I've really cleaned up my diet and yesterday was the result of a day out with friends, tea and cake and a slice of quiche. So difficult to find anything I actually enjoy eating at home, let alone at a restaurant.
Hi, had another flare up yesterday, after being reasonably ok for the last 3 weeks = I've really cleaned up my diet and yesterday was the result of a day out with friends, tea and cake and a slice of quiche. So difficult to find anything I actually enjoy eating at home, let alone at a restaurant.
Letsfixit1
in
IBS Network
3 months ago
Treatment awaited
Hi all I just completed my history incorrectly as a post. I have not posted before as I have been a silent member without any worrying ongoing elevations in PSA for about four years. I have keenly observed the posts of members and learned a good deal from them. This post is the follow up on my history
Hi all I just completed my history incorrectly as a post. I have not posted before as I have been a silent member without any worrying ongoing elevations in PSA for about four years. I have keenly observed the posts of members and learned a good deal from them. This post is the follow up on my history
Sisyphus
in
Advanced Prostate Cancer
3 months ago
My History to date
Diagnosed 09/2019 PSA 12.8 T2C Grade Group 5 - (4+5) Cores right posterior @15mm length, cores right mid and left posterior Grade Group 4 MRI showing Pi-Rads 5 lesion right side successfully targeted N0 Pet PSMA showing avidity right side of prostate and two avid lymph nodes common iliac and external
Diagnosed 09/2019 PSA 12.8 T2C Grade Group 5 - (4+5) Cores right posterior @15mm length, cores right mid and left posterior Grade Group 4 MRI showing Pi-Rads 5 lesion right side successfully targeted N0 Pet PSMA showing avidity right side of prostate and two avid lymph nodes common iliac and external
Sisyphus
in
Advanced Prostate Cancer
3 months ago
Low baseline testosterone and link to overall survival in advanced prostate cancer.
My husband’s baseline testosterone levels came back at 202. Is there a correlation between low baseline testosterone and overall survival after treatment for advanced prostate cancer? There seem to be inconclusive studies and often opposite results on the topic. So any insight would be appreciated.
My husband’s baseline testosterone levels came back at 202. Is there a correlation between low baseline testosterone and overall survival after treatment for advanced prostate cancer? There seem to be inconclusive studies and often opposite results on the topic. So any insight would be appreciated.
SherryKahn
in
Advanced Prostate Cancer
3 months ago
Update on Treatment
In June 2023, a routine PSA test value turned out to be 4.6, did an MRI; Diagnosed with Prostate Cancer, Gleason Score 7 (3+4), biopsy said one core. (Details in my profile). Opted for Active Surveillance. But in Oct 2023, PSA level went to 6.1 and in Jan 2024 PSA went to 9.2 In March 2024, did another
In June 2023, a routine PSA test value turned out to be 4.6, did an MRI; Diagnosed with Prostate Cancer, Gleason Score 7 (3+4), biopsy said one core. (Details in my profile). Opted for Active Surveillance. But in Oct 2023, PSA level went to 6.1 and in Jan 2024 PSA went to 9.2 In March 2024, did another
Sushupthi
in
Advanced Prostate Cancer
3 months ago
Cancer Metabolic Disease and Focal Therapy advances are viable.
Focal ablation laser can be successful,for early stage PCa. 10-21 . GLEASON 3-4 , 5% PSA , 4.7. After treatment. No major erection issues long term, no need for tadalafil. PSA steadily declined. Recent MRI clear 3-24. and my ejaculate ducts were saved as well. PSA 0.4. So so far so good. Get an 2nd
Focal ablation laser can be successful,for early stage PCa. 10-21 . GLEASON 3-4 , 5% PSA , 4.7. After treatment. No major erection issues long term, no need for tadalafil. PSA steadily declined. Recent MRI clear 3-24. and my ejaculate ducts were saved as well. PSA 0.4. So so far so good. Get an 2nd
Mlsliver78
in
Prostate Cancer Network
3 months ago
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