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PATIENT EXPERIENCE OF DURVALUMAB (IMFINZI)
Durvalumab (Imfinzi) will shortly be assessed by the Scottish Medicine Consortium (SMC) for use in NHS Scotland. The indication this medicine will be assessed under is: “In combination with platinum-based chemotherapy as neoadjuvant treatment, followed by durvalumab as monotherapy after surgery, is
Durvalumab (Imfinzi) will shortly be assessed by the Scottish Medicine Consortium (SMC) for use in NHS Scotland. The indication this medicine will be assessed under is: “In combination with platinum-based chemotherapy as neoadjuvant treatment, followed by durvalumab as monotherapy after surgery, is
RoyCastleHelpline
Roy Castle
in
The Roy Castle Lung Cancer Foundation
25 days ago
PSA 0? What is this?
hello fellow warriors. My husband has taken a vacation/holiday from his Zytiga and Elligard shots., Both his MO and RO agreed, it’s been 4 months since and he’s feeling so much better My question is, can you have a PSA of 0? No < than or 0. Anything , never seen this before, he started getting it
hello fellow warriors. My husband has taken a vacation/holiday from his Zytiga and Elligard shots., Both his MO and RO agreed, it’s been 4 months since and he’s feeling so much better My question is, can you have a PSA of 0? No < than or 0. Anything , never seen this before, he started getting it
Keeper70
in
Advanced Prostate Cancer
26 days ago
Decioher .93 - results said Abiraterone was effective. Can people who use this enlighten me?
Husbands urology practice does surgery, radiation, ADT but does not list Abiraterone. Their website says they will refer us out if needing chemo. Thoughts?
Husbands urology practice does surgery, radiation, ADT but does not list Abiraterone. Their website says they will refer us out if needing chemo. Thoughts?
Lastchance75
in
Advanced Prostate Cancer
26 days ago
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2 years into stage 1 prostate cancer
I'm a 68 year old married white male, smoker, active, and still working full time. I enjoy fishing, hiking, camping, playing guitar, and music from the 60s and 70s. I also take medication for an over active Thyroid and Rheumatoid Arthritis. In Aug 2023 I was diagnosed with stage 1 prostate cancer, my
I'm a 68 year old married white male, smoker, active, and still working full time. I enjoy fishing, hiking, camping, playing guitar, and music from the 60s and 70s. I also take medication for an over active Thyroid and Rheumatoid Arthritis. In Aug 2023 I was diagnosed with stage 1 prostate cancer, my
akmichael2013
in
Prostate Cancer Network
26 days ago
PSA 10.7 to 4.5 3 weeks later 45yo
3 weeks ago I had a PSA test added to my annual physical blood work. I'm very healthy and no sypmtoms. Came back at a shocking 10.7. My primary doc called me on Saturday to tell me to get an appt with urologist asap. Had an elevated WBC too. Was able to get in to see the urologist's assistant that Monday
3 weeks ago I had a PSA test added to my annual physical blood work. I'm very healthy and no sypmtoms. Came back at a shocking 10.7. My primary doc called me on Saturday to tell me to get an appt with urologist asap. Had an elevated WBC too. Was able to get in to see the urologist's assistant that Monday
Poorredman
in
Prostate Cancer Network
27 days ago
Olaparib May Be Effective Without Hormone Therapy in Some Men With Biochemically Recurrent Prostate Cancer
quite a large sub group of men with recurrent prostate cancer were able to put off psa rises and put off mets developing and reduce psa with no hornone treatment just Olaparib - LYNPARZA in short, the responders, who can be tested by gene typing, had median time of almost 4 years without adt vs the
quite a large sub group of men with recurrent prostate cancer were able to put off psa rises and put off mets developing and reduce psa with no hornone treatment just Olaparib - LYNPARZA in short, the responders, who can be tested by gene typing, had median time of almost 4 years without adt vs the
street-air
in
Advanced Prostate Cancer
27 days ago
Getting new MO Chief fellow at Hines V.A. ?
Hello Friends , Since my recurrance 3 yrs ago I have been under the care of Dr. Elizabeth Henry who works for Loyola Medical center but works at V.A. also. Having Loyala Drs. is a common sight at V.A . Dr. Henry is moving up the ladder at Loyola and she informed me that I will be getting a new MO at
Hello Friends , Since my recurrance 3 yrs ago I have been under the care of Dr. Elizabeth Henry who works for Loyola Medical center but works at V.A. also. Having Loyala Drs. is a common sight at V.A . Dr. Henry is moving up the ladder at Loyola and she informed me that I will be getting a new MO at
reconjj
in
Advanced Prostate Cancer
27 days ago
Restrospective Study of Apalutamide, Darolutamide and Enzalutamide in Patients with Nonmetastatic, Castrate Resistant Prostate Cancer
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2822870 While each of us responds differently to any prescribed drug, this new study reinforces the view that more nonmetastatic, castrate resistant prostate cancer patients may tolerate the side effects of darolutamide better compared to
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2822870 While each of us responds differently to any prescribed drug, this new study reinforces the view that more nonmetastatic, castrate resistant prostate cancer patients may tolerate the side effects of darolutamide better compared to
Survivor86
in
Advanced Prostate Cancer
28 days ago
Scientists working to understand why men with prostate cancer are at higher risk of Alzheimer's
Researchers at the Medical College of Georgia at Augusta University are searching for a better way to understand why many men with prostate cancer end up with Alzheimer's disease, and whether it's the standard hormone therapy treatment or an overactive immune response that actually contributes to the
Researchers at the Medical College of Georgia at Augusta University are searching for a better way to understand why many men with prostate cancer end up with Alzheimer's disease, and whether it's the standard hormone therapy treatment or an overactive immune response that actually contributes to the
PSAed
in
Advanced Prostate Cancer
28 days ago
Second scan -- now what?
After a year the second scan produced the following impression from the radiologist, "1. Marked improvement in radiotracer avid osteoblastic metastasis and marked improvement in radiotracer avid nodal metastasis. Radiotracer avid disease in the prostate has also markedly improved." Bear in mind that
After a year the second scan produced the following impression from the radiologist, "1. Marked improvement in radiotracer avid osteoblastic metastasis and marked improvement in radiotracer avid nodal metastasis. Radiotracer avid disease in the prostate has also markedly improved." Bear in mind that
Poollover
in
Advanced Prostate Cancer
28 days ago
Restarting anti androgens after chemo
My husband has completed two years of chemotherapy, followed by Pluvicto. Would it be possible to re-start an anti-androgen ( Zytiga, daralutimide) as therapy? What choices does he have going forward?
My husband has completed two years of chemotherapy, followed by Pluvicto. Would it be possible to re-start an anti-androgen ( Zytiga, daralutimide) as therapy? What choices does he have going forward?
roboocme
in
Advanced Prostate Cancer
28 days ago
Docosahexaenoic acid enhances the treatment efficacy for CRPCa by inhibiting autophagy through Atg4B inhibition, 2024 Aug 23
Possible simple dietary intervention to increase autophagy in PCa and boost efficacy of ARSIs. Abstract & Intro (+ Section snippets in ScienceDirect link): * * * [u][i]
Abstract
[/i][/u] [i]
Autophagy induction in cancer is involved in cancer progression and the acquisition of resistance to
Possible simple dietary intervention to increase autophagy in PCa and boost efficacy of ARSIs. Abstract & Intro (+ Section snippets in ScienceDirect link): * * * [u][i]
Abstract
[/i][/u] [i]
Autophagy induction in cancer is involved in cancer progression and the acquisition of resistance to
cujoe
in
Fight Prostate Cancer
28 days ago
Ideas for resistance training which can be done at home ?
I am looking for ideas for resistance training which can be done at home for my father who is 83 yrs and has bone mets in upper femurs , acetabulum , ischeum and some other bones in the body. He also has osteoporosis in femurs but not in hips. He is on orgovyx and xtandi. He walks an hour daily
I am looking for ideas for resistance training which can be done at home for my father who is 83 yrs and has bone mets in upper femurs , acetabulum , ischeum and some other bones in the body. He also has osteoporosis in femurs but not in hips. He is on orgovyx and xtandi. He walks an hour daily
Tinkudi
in
Advanced Prostate Cancer
29 days ago
Why is my PSA so low?
For about 9 years after my last HIFU, my PSA hovered in the 1.0 - 2.0 range, and testosterone around 200 or so. That's what they were in July 2023. But in January 2024, PSA plunged to 0.248 (T wasn't measured then). In early March, PSA continued down to 0.148, and testosterone crashed to 60, and free
For about 9 years after my last HIFU, my PSA hovered in the 1.0 - 2.0 range, and testosterone around 200 or so. That's what they were in July 2023. But in January 2024, PSA plunged to 0.248 (T wasn't measured then). In early March, PSA continued down to 0.148, and testosterone crashed to 60, and free
kapakahi
in
Advanced Prostate Cancer
29 days ago
Stage 3 curative?
HiMy mum (76 years old with COPD and emphysema) was diagnosed on 17 June with stage 3 nsclc with localised spread to a rib and lymph node. She has her 20th and last radiotherapy dose tomorrow. The oncologist said he was aiming for curative. There has been no mention of chemo or targeted therapy. Is this
HiMy mum (76 years old with COPD and emphysema) was diagnosed on 17 June with stage 3 nsclc with localised spread to a rib and lymph node. She has her 20th and last radiotherapy dose tomorrow. The oncologist said he was aiming for curative. There has been no mention of chemo or targeted therapy. Is this
Lesleypod
in
The Roy Castle Lung Cancer Foundation
29 days ago
New diagnosis... & Enzalutamide question
Hi guys, I've been reading these APC posts for a few weeks and I have to say that I massively appreciate your shared knowledge, humour... and grace. It's helped me face where I am, and not paint it too black. Thank you! DX start of July, PSA 530, Gleason 7 (4,3), low volume Metastatic PC with extensive
Hi guys, I've been reading these APC posts for a few weeks and I have to say that I massively appreciate your shared knowledge, humour... and grace. It's helped me face where I am, and not paint it too black. Thank you! DX start of July, PSA 530, Gleason 7 (4,3), low volume Metastatic PC with extensive
Broccoli24
in
Advanced Prostate Cancer
29 days ago
72 year old
So I am a 72 (soon to be 73) White male. I was diagnosed with prostate cancer about 18-20 months ago. I have had three biopsies. The first two were transrectal approach and the last one was peritoneal approach. No issues with either approach. They are painless as they give you a drug to put you
So I am a 72 (soon to be 73) White male. I was diagnosed with prostate cancer about 18-20 months ago. I have had three biopsies. The first two were transrectal approach and the last one was peritoneal approach. No issues with either approach. They are painless as they give you a drug to put you
Dadyrabbit
in
Advanced Prostate Cancer
29 days ago
Retrospective cohort study comparing ARIs; darolutamide, enzalutamide, and apalutamide in 870 non metastatic CRPC patients
In this retrospective study (with limitations) comparing ARIs, darolutamide came out best. The results for enzalutamide and apalutamide were similar. Androgen Receptor Inhibitors in Patients With Nonmetastatic Castration-Resistant Prostate Cancer Daniel J. George, MD; Alicia K. Morgans, MD, MPH; Niculae
In this retrospective study (with limitations) comparing ARIs, darolutamide came out best. The results for enzalutamide and apalutamide were similar. Androgen Receptor Inhibitors in Patients With Nonmetastatic Castration-Resistant Prostate Cancer Daniel J. George, MD; Alicia K. Morgans, MD, MPH; Niculae
Graham49
in
Advanced Prostate Cancer
29 days ago
Elevated Testosterone
I was on Abiraterone and prednisone for 6 months until June 6, 2024. My blood work: 4/25/2024 Testosterone 44 ng/dL, PSA undetectable 5/28 T 35, PSA undetectable 6/6 Stopped Abiraterone 7/8 T 968 PSA 0.21 8/19 T 1475 PSA 0.54 My MO want's to do a PSMA scan in a month. I don't see
I was on Abiraterone and prednisone for 6 months until June 6, 2024. My blood work: 4/25/2024 Testosterone 44 ng/dL, PSA undetectable 5/28 T 35, PSA undetectable 6/6 Stopped Abiraterone 7/8 T 968 PSA 0.21 8/19 T 1475 PSA 0.54 My MO want's to do a PSMA scan in a month. I don't see
rainlessman
in
Advanced Prostate Cancer
29 days ago
Good news after SBRT
My last PSMA pet showed an 8mm prostate tumor in my left lung. My PSA before the radiation was 1.06. 2 weeks after radiation the PSA is <.06. I'm seeing my MO tomorrow to see if he will continue to hold off on ADT. Any suggestion/recommendations? Thanks
My last PSMA pet showed an 8mm prostate tumor in my left lung. My PSA before the radiation was 1.06. 2 weeks after radiation the PSA is <.06. I'm seeing my MO tomorrow to see if he will continue to hold off on ADT. Any suggestion/recommendations? Thanks
old64horn
in
Advanced Prostate Cancer
29 days ago
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