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Focal Ablation doesn't work (again)
Cryo joins HIFU, FLA, and IRE as substandard focal thermoablation therapies. Aker et al. reported (below) that on biopsy 18 months post-treatment, 35% still had clinically significant prostate cancer (only 46% had no prostate cancer), and that neither MRI nor PSA were good indicators of treatment failure
Cryo joins HIFU, FLA, and IRE as substandard focal thermoablation therapies. Aker et al. reported (below) that on biopsy 18 months post-treatment, 35% still had clinically significant prostate cancer (only 46% had no prostate cancer), and that neither MRI nor PSA were good indicators of treatment failure
Tall_Allen
in
Prostate Cancer Network
1 year ago
Ambroxol
Would anyone share if you have participated in a clinical trial using the drug Ambroxol for PD? There have been several clinical trials which have published encouraging resusts, mostly in the UK. I am not formally in a trial but have been duplicating the dosage for about 12 months. My experience is favorable
Would anyone share if you have participated in a clinical trial using the drug Ambroxol for PD? There have been several clinical trials which have published encouraging resusts, mostly in the UK. I am not formally in a trial but have been duplicating the dosage for about 12 months. My experience is favorable
Badmouth
in
Cure Parkinson's
1 year ago
Successful Eye Exam
Dear All, Today I had an Eye Exam at my local Boots Opticians, it should have been Yesterday but 'They' had Staff Training, As always The Optician was Very Thorough, checking both my Vision and- most important to me- my left eye for signs of Vasculitis, which was 'Clear'. Apart from a slight 'change
Dear All, Today I had an Eye Exam at my local Boots Opticians, it should have been Yesterday but 'They' had Staff Training, As always The Optician was Very Thorough, checking both my Vision and- most important to me- my left eye for signs of Vasculitis, which was 'Clear'. Apart from a slight 'change
AndrewT
in
Vasculitis UK
2 years ago
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I'm at a loss and falling into depression
I feel like I'm falling down a hole my depression is at an all time high. I cry myself to sleep more nights then I care to admit. It's gotten to the point where I even wish something bad would happen to me (like a freak accident) and I would die, I can't help but feel like the world is better off without
I feel like I'm falling down a hole my depression is at an all time high. I cry myself to sleep more nights then I care to admit. It's gotten to the point where I even wish something bad would happen to me (like a freak accident) and I would die, I can't help but feel like the world is better off without
Lookingforhope20100
in
Anxiety and Depression Support
1 year ago
Any advice about future treatment?
Good morning sisters, I am at yet another crossroads and hoping for some advice. Diagnosed stage 4 high grade serous Jan 2020, had two surgeries, three courses of chemo (in total), short lived Niraparib, failed clinical trial (PICCOLO). So now having the 6th and final chemo of this third course ( Carboplatin
Good morning sisters, I am at yet another crossroads and hoping for some advice. Diagnosed stage 4 high grade serous Jan 2020, had two surgeries, three courses of chemo (in total), short lived Niraparib, failed clinical trial (PICCOLO). So now having the 6th and final chemo of this third course ( Carboplatin
Riverflo
in
My Ovacome
1 year ago
RA, Sjogrens desease, Cataracts in both eyes, now Lupus?
Hi All, Can anyone tell me if there is any medication that can help with Lupus? I’m taking Hydroxychloroquine, + several pain killers. The Sjogrens is causing a lot of problems with my eyes, now Lupus is showing it’s ugly head. It would be nice if anyone has any help they can offer.
Hi All, Can anyone tell me if there is any medication that can help with Lupus? I’m taking Hydroxychloroquine, + several pain killers. The Sjogrens is causing a lot of problems with my eyes, now Lupus is showing it’s ugly head. It would be nice if anyone has any help they can offer.
wakeham
in
NRAS
2 years ago
DVLA- Lost Licence due to VF
HI, I was wondering if anyone has any advice or experience in getting a driver's licence back! Quick background- diagnosed with well-developed Glaucoma a few days after birth in left eye (plus cataract, nystagmus, squint and a fixed iris) Lost sight completely by age 13/14. Glaucoma was identified
HI, I was wondering if anyone has any advice or experience in getting a driver's licence back! Quick background- diagnosed with well-developed Glaucoma a few days after birth in left eye (plus cataract, nystagmus, squint and a fixed iris) Lost sight completely by age 13/14. Glaucoma was identified
ToeJam
in
Glaucoma UK
2 years ago
To those who replied to my question on clinical trials
To those who replied to my question on joining clinical trials, I am overwhelmed by your kindness in sending me emails. I will answer your emails soon but I am currently recovering from a cataract operation and though my eyesight has improved a lot I still have difficulty reading and writing. Bear
To those who replied to my question on joining clinical trials, I am overwhelmed by your kindness in sending me emails. I will answer your emails soon but I am currently recovering from a cataract operation and though my eyesight has improved a lot I still have difficulty reading and writing. Bear
MyMiracle13
in
SHARE Metastatic Breast Cancer
1 year ago
DepressionAnd Anxiety Suck!
It’s bad enough suffering from one or the other, but both??!! That’s a lot to put up with! Especially when you are going through storms and my Mine doesn’t know if it is depressed, anxious or attempting to cope. It’s unbelievable and you all understand how horrible it can be. I’ve been without meds since
It’s bad enough suffering from one or the other, but both??!! That’s a lot to put up with! Especially when you are going through storms and my Mine doesn’t know if it is depressed, anxious or attempting to cope. It’s unbelievable and you all understand how horrible it can be. I’ve been without meds since
Singingmoose
in
Anxiety and Depression Support
1 year ago
First post in around two years
I just thought I would drop in and say hi, and good to see some familiar names still around. For six months when I was here previously I tried my best to assist and support others and their queries as a survivor and have continued to do so elsewhere but to a more limited extent. Covid being less
I just thought I would drop in and say hi, and good to see some familiar names still around. For six months when I was here previously I tried my best to assist and support others and their queries as a survivor and have continued to do so elsewhere but to a more limited extent. Covid being less
Shreds
in
Headway
2 years ago
Would appreciate any support❤
Hi all im going through a really tough time now, and I would appreciate any support.The last few months have been really difficult for me. I developed severe ptsd as a result of a traumatic situation at work. I have always had social anxiety but my social anxiety has reached an all time high. When I
Hi all im going through a really tough time now, and I would appreciate any support.The last few months have been really difficult for me. I developed severe ptsd as a result of a traumatic situation at work. I have always had social anxiety but my social anxiety has reached an all time high. When I
Rose23456
in
Anxiety and Depression Support
1 year ago
Panic over cataract surgery
Hi friends I'm writing this as mum is on the toilet. She has cataract surgery due at 12.30 today but it is now 10.15 and mum needs a number 2. I'm worried we will not make it to hospital as she takes over an hour sometimes two to finish and then I have to wash and shower her. It takes an hour to get
Hi friends I'm writing this as mum is on the toilet. She has cataract surgery due at 12.30 today but it is now 10.15 and mum needs a number 2. I'm worried we will not make it to hospital as she takes over an hour sometimes two to finish and then I have to wash and shower her. It takes an hour to get
Cinderella80
in
PSP Association
2 years ago
Lingering delusions / beliefs
Hi all I was just wondering how long delusions/beliefs remain for? I am really struggling with the worries I had at the time during psychosis as they still feel quite real to me. It’s really affecting the way I interact with my partner, baby, family and friends. I can’t imagine not ever thinking the
Hi all I was just wondering how long delusions/beliefs remain for? I am really struggling with the worries I had at the time during psychosis as they still feel quite real to me. It’s really affecting the way I interact with my partner, baby, family and friends. I can’t imagine not ever thinking the
Loopy86
in
Action on Postpartum Psychosis
1 year ago
Effect of Melatonin Administration on Mitochondrial Activity and Oxidative Stress Markers in Patients with Parkinson's Disease 2021
Effect of Melatonin Administration on Mitochondrial Activity and Oxidative Stress Markers in Patients with Parkinson's Disease 2021
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545577/ Abstract Mitochondrial dysfunction and oxidative stress are extensively linked to Parkinson's disease (PD)
Effect of Melatonin Administration on Mitochondrial Activity and Oxidative Stress Markers in Patients with Parkinson's Disease 2021
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545577/ Abstract Mitochondrial dysfunction and oxidative stress are extensively linked to Parkinson's disease (PD)
Bolt_Upright
in
Cure Parkinson's
1 year ago
IVIG after heart surgery and stopping IBRUTIMIB
12 months ago I was on an Ibrutinib clinical trial for my CLL. Ibrutinib worked great for me for years. I found out I needed a triple bypass due to 95% LAD artery blockage. Not good! A stent wasn’t an option in my case due to necessity for blood thinners. Can’t do blood thinners, aspirin and Irbutinib
12 months ago I was on an Ibrutinib clinical trial for my CLL. Ibrutinib worked great for me for years. I found out I needed a triple bypass due to 95% LAD artery blockage. Not good! A stent wasn’t an option in my case due to necessity for blood thinners. Can’t do blood thinners, aspirin and Irbutinib
misterbee
in
CLL Support
1 year ago
Depression, anxiety and irritability on peginterferon
Are people who are already taking anti depressants finding that they have to up their doses after taking peginterferon for pv?
Are people who are already taking anti depressants finding that they have to up their doses after taking peginterferon for pv?
Hollyhedge
in
MPN Voice
1 year ago
Little laughter 🤭 🤪
Woke up to snow ❄️ this morning. Had to cover my bad foot and put a shoe and coat on to dig out Rozy’s doggie door. The wind was 25 mph and blu snow off roof and was2’ deep in front of doggie door. Didn’t do much but got it cleared out so she can use it. A friend is coming over later this afternoon or
Woke up to snow ❄️ this morning. Had to cover my bad foot and put a shoe and coat on to dig out Rozy’s doggie door. The wind was 25 mph and blu snow off roof and was2’ deep in front of doggie door. Didn’t do much but got it cleared out so she can use it. A friend is coming over later this afternoon or
Kenu
in
My MSAA Community
2 years ago
Recovery while manic
Today is day 9 of my recovery. Since my last post on this log. I am going through the withdrawal process and I feel like I need to score. It sucks to say "I like to get high when I'm feeling low". I've been working on myself for 12yrs now. And these days I'm really wanting to quit my old habits and grow
Today is day 9 of my recovery. Since my last post on this log. I am going through the withdrawal process and I feel like I need to score. It sucks to say "I like to get high when I'm feeling low". I've been working on myself for 12yrs now. And these days I'm really wanting to quit my old habits and grow
Rayman559
in
Above & Beyond
1 year ago
Volunteer Opportunity - Prostate Cancer Patient Advocate with SWOG for Genitourinary Cancer Committee
I have served as a volunteer Patient Advocate representing the LGBTQ+ Community with the Southwest Oncology Group (SWOG) for the past two years. As such I am serving as a member of the Patient Advocacy Committee (PAC) and the Diversity, Equality, and Inclusion Committee. I attend monthly zoom meetings
I have served as a volunteer Patient Advocate representing the LGBTQ+ Community with the Southwest Oncology Group (SWOG) for the past two years. As such I am serving as a member of the Patient Advocacy Committee (PAC) and the Diversity, Equality, and Inclusion Committee. I attend monthly zoom meetings
JRPnSD
in
Advanced Prostate Cancer
1 year ago
HAS ANYONE PARTICIPATED IN CLINICAL TRIALS
Hello everyone. Has anybody on this forum ever joined in a clinical trial? I have been invited to join a Phase 1 clinical trial for LOXO-783. The new drug is for those who have the PIK3CA mutation. At first I was very excited to join but when I was looking at the screening requirements, I don’t
Hello everyone. Has anybody on this forum ever joined in a clinical trial? I have been invited to join a Phase 1 clinical trial for LOXO-783. The new drug is for those who have the PIK3CA mutation. At first I was very excited to join but when I was looking at the screening requirements, I don’t
MyMiracle13
in
SHARE Metastatic Breast Cancer
1 year ago
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