How long before methotexrate 'kicks-in'?

[Udupik]

I have been taking MTX for past 17 weeks ( last 2 weeks by injection) for treatment of uveitis. But I see no change in the inflammation and the recent FFA reveals that the inflammation is active . Do I need to wait more or will the rhumetalogist add another DMARD ( or even biologicals ) to speed up the treatment?

[piglette]

Methotrexate may take up to six months to show its optimal benefits. You will have to talk to your rheumatologist about it. Corticosteroids are sometime given in the interim.

[Udupik in reply to piglette]

Thanks . I'm on a low tapered dose of steroids and the opthalmologist has offered a suggestion of taking an ozurdex implant ( the second in left eye ) during this waiting period for MTX to do its job

[piglette in reply to Udupik]

An ozurdex implant is a good way of getting the steroids. It sounds like you are being looked after well.

[AmyS1]

Uveitis is serious you need expertise of experienced ophthalmologist.

[Udupik]

Yes. I do have an experienced opthalmologist. My issue is with the waiting period of methotexrate. If you have had it, after how long did it start working for you?