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GCA candidate Tremfya fails to meet clinical trial objectives
Here in the US, Johnson & Johnson announced today it is halting its Phase 2 "THEIA" trial as the numbers of enrolled GCA patients did not, unfortunately, achieve the level of remission hoped for. If you're inclined to read the technical details, you can google Janssen Rheumatology's data.
Here in the US, Johnson & Johnson announced today it is halting its Phase 2 "THEIA" trial as the numbers of enrolled GCA patients did not, unfortunately, achieve the level of remission hoped for. If you're inclined to read the technical details, you can google Janssen Rheumatology's data.
Optim11
in
PMRGCAuk
2 months ago
Disease remission achieved in SLE with dual-target CAR T-cell therapy
Disease remission achieved in SLE with dual-target CAR T-cell therapy Nearly all patients in small trial see long-term medication-free remission Nearly all people with systemic lupus erythematosus (SLE) treated with iCell Gene Therapeutics’ dual-target CAR T-cell therapy achieved medication-free
Disease remission achieved in SLE with dual-target CAR T-cell therapy Nearly all patients in small trial see long-term medication-free remission Nearly all people with systemic lupus erythematosus (SLE) treated with iCell Gene Therapeutics’ dual-target CAR T-cell therapy achieved medication-free
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 months ago
Be careful: Pluvicto controversy, dammit!
not saying that it does not work, in fact for some patients it is simply fantastic, but still...they have damaged their reputation with patients https://www.nature.com/articles/s44276-024-00065-7 The PSMAfore and VISION trials for Lutetium-177 PSMA-617 in prostate cancer exhibit design flaws that bias
not saying that it does not work, in fact for some patients it is simply fantastic, but still...they have damaged their reputation with patients https://www.nature.com/articles/s44276-024-00065-7 The PSMAfore and VISION trials for Lutetium-177 PSMA-617 in prostate cancer exhibit design flaws that bias
Maxone73
in
Advanced Prostate Cancer
2 months ago
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Shift Needed in Research, Treatment, Care for Aging MS Population
NASHVILLE, Tennessee — For the first time, the majority of patients with multiple sclerosis (MS) in the United States are, or soon will be, over age 55, a phenomenon that's driving a shift in priorities including the creation of MS aging centers and a push for more clinical trials aimed at this growing
NASHVILLE, Tennessee — For the first time, the majority of patients with multiple sclerosis (MS) in the United States are, or soon will be, over age 55, a phenomenon that's driving a shift in priorities including the creation of MS aging centers and a push for more clinical trials aimed at this growing
BettysMom
in
My MSAA Community
2 months ago
Anti depressants
I’m desperate for help - i was on anti depressants for 12 years for ocd I had no idea you don’t stay on them for life!!! Husband was always saying it as did the dr at my one review mid 30’s. When I went on I was desperate for babies but as time went on they numbed everything. I came off last year after
I’m desperate for help - i was on anti depressants for 12 years for ocd I had no idea you don’t stay on them for life!!! Husband was always saying it as did the dr at my one review mid 30’s. When I went on I was desperate for babies but as time went on they numbed everything. I came off last year after
Mexicosunnydays
in
Fertility Network UK
2 months ago
Zanubrutinib or Venetaclax with Gazyva??
Can everyone please tell me their experience with these treatments? I’ve been given the options of either if trial not ready. I was suppose to start a phase 3 clinical trial at Moffitt but it’s been delayed at least 3-4 weeks and I may need to start treatment sooner. Thanks in advance….
Can everyone please tell me their experience with these treatments? I’ve been given the options of either if trial not ready. I was suppose to start a phase 3 clinical trial at Moffitt but it’s been delayed at least 3-4 weeks and I may need to start treatment sooner. Thanks in advance….
Nana1961
in
CLL Support
2 months ago
New person
Hi. Intro here. I always knew I wasn't right since extreme childhood trauma from birth to 15 (without going into all the physical, emotional. psychological, mental trauma) and then an 18-year marriage of the same. So I've never been treated for anxiety and depression and I'm sure it's what I have. Prolly
Hi. Intro here. I always knew I wasn't right since extreme childhood trauma from birth to 15 (without going into all the physical, emotional. psychological, mental trauma) and then an 18-year marriage of the same. So I've never been treated for anxiety and depression and I'm sure it's what I have. Prolly
Den2542
in
Anxiety Support
2 months ago
Sertraline/Zoloft experiences?
Hi. I started sertraline about two weeks ago (25mg/d). I think that I'm less irritable, better able to cope and don't get sucked down so deeply into rumination. Hoping for further improvement and might consider increasing dose in a month. If you've taken S/Z, what has your experience been? How long
Hi. I started sertraline about two weeks ago (25mg/d). I think that I'm less irritable, better able to cope and don't get sucked down so deeply into rumination. Hoping for further improvement and might consider increasing dose in a month. If you've taken S/Z, what has your experience been? How long
rescuedbydogs
in
Anxiety and Depression Support
2 months ago
RB-190 - A drug repurposed - for Parkinsons
There is hope! A drug repurposed for Parkinsons may become a game changer. Dr. Jonathan Sackner-Bernstein is working on a clinical trial (stage 2) for a repurposed drug for Parkinsons patients. He says, and all Parkinson's neurologists know that Parkinsons patients have little dopamine in their brains
There is hope! A drug repurposed for Parkinsons may become a game changer. Dr. Jonathan Sackner-Bernstein is working on a clinical trial (stage 2) for a repurposed drug for Parkinsons patients. He says, and all Parkinson's neurologists know that Parkinsons patients have little dopamine in their brains
Osteopathic
in
Cure Parkinson's
2 months ago
Low Red Cell Count
Morning folks, I wanted to provide an update on my journey. Dropped from clinical trial at Sarah Cannon Research in early May due to disease progression after three treatments of Phase 1 trial drug and one dose of Keytruda. Started dual chemo cabazitaxel and carboplatin in mid May. Went for third
Morning folks, I wanted to provide an update on my journey. Dropped from clinical trial at Sarah Cannon Research in early May due to disease progression after three treatments of Phase 1 trial drug and one dose of Keytruda. Started dual chemo cabazitaxel and carboplatin in mid May. Went for third
Pmann
in
Advanced Prostate Cancer
2 months ago
My Mum's story.
Hello everyone. I thought I would share my Mum's story with you all. She recently passed away at the beginning of June, in her safe place (home) with her family beside her. For that I am eternally grateful, and I know that she was too. It's a complex story, but basically after I was born (youngest
Hello everyone. I thought I would share my Mum's story with you all. She recently passed away at the beginning of June, in her safe place (home) with her family beside her. For that I am eternally grateful, and I know that she was too. It's a complex story, but basically after I was born (youngest
JPB08
in
Action on Postpartum Psychosis
2 months ago
Hope Biosciences Stem Cell Trial
I am participating in the clinical trial of mesenchymal stem cells at Hope Biosciences in Houston, Texas. I am Patient 54 out of 60 they plan to enroll. I had my first infusion yesterday, with no obvious concerns or ill effects. As my treatments progress, I would like to privately compare notes with
I am participating in the clinical trial of mesenchymal stem cells at Hope Biosciences in Houston, Texas. I am Patient 54 out of 60 they plan to enroll. I had my first infusion yesterday, with no obvious concerns or ill effects. As my treatments progress, I would like to privately compare notes with
jimcaster
in
Cure Parkinson's
2 months ago
TRUST IN HEALTHCARE : free registration at https://malecare.org/trust-in-healthcare
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Darryl
Partner
in
Prostate Cancer Network
2 months ago
TRUST IN HEALTHCARE : free virtual conference for patients, friends and those you care about
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Darryl
Partner
in
LGBT Cancer Community
2 months ago
DO YOU TRUST YOUR DOCTOR : Free registration at https://malecare.org/trust-in-healthcare
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Darryl
Partner
in
Advanced Prostate Cancer
2 months ago
DO YOU TRUST YOUR DOCTOR? Free registration at malecare.org/trust-in-healthcare
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET (New York time) Register with your email for free at https://malecare.org/trust-in-healthcare Prostate Cancer Research (PCR) is a patient-centric
Darryl
Partner
in
Active Surveillance - Prostate Cancer
2 months ago
Clinical trials for IBS
Hi, does anyone know where I can find IBS clinical trials to participate in?
Hi, does anyone know where I can find IBS clinical trials to participate in?
Emeraldtiger1
in
IBS Network
2 months ago
Struggling
I'm really struggling this morning. I've had severe anxiety and depression for about a year and a half (actually my whole life), and nothing seems to be helping. I'm on 450 mg. Wellbutrin (the 5th anti-depressant I've tried), getting therapy once a week and trying to stay busy. I don't have any close
I'm really struggling this morning. I've had severe anxiety and depression for about a year and a half (actually my whole life), and nothing seems to be helping. I'm on 450 mg. Wellbutrin (the 5th anti-depressant I've tried), getting therapy once a week and trying to stay busy. I don't have any close
Woolybluecurl
in
Anxiety and Depression Support
2 months ago
Solving Restless Legs
Medscape have a report issued on June 14th on some new interesting research It is entitled; Solving Restless Legs: Largest Genetic Study to Date May Help and is written by Lisa Marshall and published in Medscape June 14, 2024 I think it is worth our while to know something about it so for
Medscape have a report issued on June 14th on some new interesting research It is entitled; Solving Restless Legs: Largest Genetic Study to Date May Help and is written by Lisa Marshall and published in Medscape June 14, 2024 I think it is worth our while to know something about it so for
thorp
in
Restless Legs Syndrome
2 months ago
AI to predict clinical trials outcome
"Dr. Sabbagh explains that traditional endpoints like overall survival often require long follow-ups, delaying access to potentially life-saving treatments. His research leverages baseline clinical characteristics and PSA changes over four months to accelerate predictions of trial outcomes. " It would
"Dr. Sabbagh explains that traditional endpoints like overall survival often require long follow-ups, delaying access to potentially life-saving treatments. His research leverages baseline clinical characteristics and PSA changes over four months to accelerate predictions of trial outcomes. " It would
Maxone73
in
Advanced Prostate Cancer
2 months ago
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