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The Importance of Peer-Review
It takes the impartial analysis of an outside expert to see the confirmation bias that may be blinding the lead investigator of a Phase 3
clinical
trial. Although Phase 3
trials
are Level 1 evidence, they still must be graded by outside experts.
It takes the impartial analysis of an outside expert to see the confirmation bias that may be blinding the lead investigator of a Phase 3
clinical
trial. Although Phase 3
trials
are Level 1 evidence, they still must be graded by outside experts.
Tall_Allen
in
Advanced Prostate Cancer
7 months ago
Hot off the press. Randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson’s disease.
Our results support extending the dose range of NR in phase II
clinical
trials
to 3000 mg per day, with appropriate safety monitoring. https://www.nature.com/articles/s41467-023-43514-6
Our results support extending the dose range of NR in phase II
clinical
trials
to 3000 mg per day, with appropriate safety monitoring. https://www.nature.com/articles/s41467-023-43514-6
SilentEchoes
in
Cure Parkinson's
10 months ago
CLL and mRNA Vaccines
id=10.1371/journal.pmed.1004157 I don't understand most of it, but this is one of the "Findings": [i]CLL patients and other immunocompromised populations may benefit from alternative vaccine regimens, which should be evaluated in
clinical
trials
.
id=10.1371/journal.pmed.1004157 I don't understand most of it, but this is one of the "Findings": [i]CLL patients and other immunocompromised populations may benefit from alternative vaccine regimens, which should be evaluated in
clinical
trials
.
BWHR
in
CLL Support
1 year ago
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Will Existing Drugs Stop Cancer's Bone Spread? I don't know but it's driving me crazy!
I am inclined to think about Ivermectin as one of the possible components of the cocktail, but just because there have been tonnes of positive pre-
clinical
trials
about it... We need some internal source! A good old snitch! https://english.tau.ac.il/research/study-breast-cancer-meds
I am inclined to think about Ivermectin as one of the possible components of the cocktail, but just because there have been tonnes of positive pre-
clinical
trials
about it... We need some internal source! A good old snitch! https://english.tau.ac.il/research/study-breast-cancer-meds
Maxone73
in
Fight Prostate Cancer
4 months ago
Finally!
The bit I need help with is this:- [i]As neither liothyronine monotherapy nor combined levothyroxine and liothyronine therapy are considered to be standard care (as there are no
clinical
trials
indicating that using liothyronine is superior to levothyroxine monotherapy) there is no all Wales protocol
The bit I need help with is this:- [i]As neither liothyronine monotherapy nor combined levothyroxine and liothyronine therapy are considered to be standard care (as there are no
clinical
trials
indicating that using liothyronine is superior to levothyroxine monotherapy) there is no all Wales protocol
serenfach
in
Thyroid UK
10 months ago
Spotlight on Chronic Lymphocytic Leukemia (CLL) May 24, 2023 Nicole Lamanna, MD- replay, slides and transcript
Spotlight on Chronic Lymphocytic Leukemia (CLL) May 24, 2023 Nicole Lamanna, MD https://www.lls.org/patient-education-webcasts/spotlight-chronic-lymphocytic-leukemia-cll https://youtu.be/6KziJk3zQ_I Topics Covered: Emerging therapies and
clinical
trials
for CLL Managing side effects Strategies
Spotlight on Chronic Lymphocytic Leukemia (CLL) May 24, 2023 Nicole Lamanna, MD https://www.lls.org/patient-education-webcasts/spotlight-chronic-lymphocytic-leukemia-cll https://youtu.be/6KziJk3zQ_I Topics Covered: Emerging therapies and
clinical
trials
for CLL Managing side effects Strategies
lankisterguy
Volunteer
in
CLL Support
1 year ago
being redundant
Actually I started when doing chemo because i had read a few article (from major medical institution but not
clinical
trials
) explaining the mechanisms by which ivermectin can add to the effectiveness of conventional chemo treatments. This is not why I am suggesting this podcast again.
Actually I started when doing chemo because i had read a few article (from major medical institution but not
clinical
trials
) explaining the mechanisms by which ivermectin can add to the effectiveness of conventional chemo treatments. This is not why I am suggesting this podcast again.
spencoid2
in
Advanced Prostate Cancer
11 months ago
CLL survival times ARE improving, thanks to BTK and BCL-2 inhibitors
trials
showing improved overall survival compared to chemotherapeutic agents.
trials
showing improved overall survival compared to chemotherapeutic agents.
AussieNeil
Partner
in
CLL Support
6 months ago
Stanford Gloves Development: New Patent Granted Oct 12
I've only skimmed it but the link to download the PDF is here: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20230321436 It's been my hypothesis that the hold up on further
clinical
trials
of the glove that are needed to get FDA approval, have been on hold waiting for a patent to
I've only skimmed it but the link to download the PDF is here: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20230321436 It's been my hypothesis that the hold up on further
clinical
trials
of the glove that are needed to get FDA approval, have been on hold waiting for a patent to
Neurosmith
in
Cure Parkinson's
1 year ago
Pursuing Smaller, Faster Clinical Trials For Progressive Neurological Disorders
https://www.clinicalleader.com/doc/pursuing-smaller-faster-
clinical
-
trials
-for-progressive-neurological-disorders-0001
https://www.clinicalleader.com/doc/pursuing-smaller-faster-
clinical
-
trials
-for-progressive-neurological-disorders-0001
Farooqji
in
Cure Parkinson's
1 year ago
Webinar:What role does our immune system play in the development of AMD?
If we can better understand how mutations in the CFI gene can cause damage, patients could be screened for those mutations and this could lead to
clinical
trials
or treatments tailored to the patients.
If we can better understand how mutations in the CFI gene can cause damage, patients could be screened for those mutations and this could lead to
clinical
trials
or treatments tailored to the patients.
Carol_MacularSociety
Partner
in
Macular Society
11 months ago
Cancer causation -- inflammation and statistics
Along the way, we can review the benefits and drawbacks of correlation (such as proximity) not being causation and the Fisherian statistics that support the scientific studies and
clinical
trials
we all rely on.
Along the way, we can review the benefits and drawbacks of correlation (such as proximity) not being causation and the Fisherian statistics that support the scientific studies and
clinical
trials
we all rely on.
mistersafety
in
Advanced Prostate Cancer
10 months ago
ERX-41
There are at present paid for
clinical
trials
, as I understand in the UK offering those of a certain age a reward of a little over £7000. Posted this because if anyone can tell more about it there is plenty of space here. Thanks much. Rita44
There are at present paid for
clinical
trials
, as I understand in the UK offering those of a certain age a reward of a little over £7000. Posted this because if anyone can tell more about it there is plenty of space here. Thanks much. Rita44
Hidden
in
My Ovacome
1 year ago
Funding of drugs and clinical trials.
I would also like to know what part those companies play in
clinical
trials
and what process is used to decide when and where those trials take place?
I would also like to know what part those companies play in
clinical
trials
and what process is used to decide when and where those trials take place?
Kiwidi
in
CLL Support
1 year ago
📢 Saturday October 14th Free Live HCC Workshop📢
With groundbreaking
clinical
trials
on immunotherapy, cellular therapy, and patient assessments, he is at the forefront of enhancing the quality of life for liver cancer patients. Dr.
With groundbreaking
clinical
trials
on immunotherapy, cellular therapy, and patient assessments, he is at the forefront of enhancing the quality of life for liver cancer patients. Dr.
MichelleL_BlueFaery
Editor
in
Blue Faery Liver Cancer
1 year ago
New Pancreatitis Therapies: Current Clinical Trials! | Webinar Registration is now OPEN
Register now to secure your spot visiting: https://us02web.zoom.us/webinar/register/3016898628415/WN_Co2NBPUSTyS307Iuwlk95Q Please know that the
clinical
trials
this webinar will discuss are U.S.-based.
Register now to secure your spot visiting: https://us02web.zoom.us/webinar/register/3016898628415/WN_Co2NBPUSTyS307Iuwlk95Q Please know that the
clinical
trials
this webinar will discuss are U.S.-based.
Skye_MC
Administrator
in
Chronic Pancreatitis Support
1 year ago
clinical trial expected to be 2 to 5 years away, but still…TALEN-Engineered CAR-T Cells Deliver Precision Attack on Solid Tumours
as programmer I always thought that to decrease side effects of drugs we needed to implement logical AND and IF/THEN conditional instructions…but these guys were able to actually do that https://crisprmedicinenews.com/news/talen-engineered-car-t-cells-deliver-precision-attack-on-solid-tumours/
as programmer I always thought that to decrease side effects of drugs we needed to implement logical AND and IF/THEN conditional instructions…but these guys were able to actually do that https://crisprmedicinenews.com/news/talen-engineered-car-t-cells-deliver-precision-attack-on-solid-tumours/
Maxone73
in
Advanced Prostate Cancer
10 hours ago
Recently diagnosed with MF
After about 5 years of changing diagnoses, CML, PV, ET, my husband has been told his condition has progressed to MF, based on rapidly enlarged spleen and latest BMB. Our appointment with the consultant was a bit of a blur after the shock of her saying his life expectancy is approx 80 months, so we have
After about 5 years of changing diagnoses, CML, PV, ET, my husband has been told his condition has progressed to MF, based on rapidly enlarged spleen and latest BMB. Our appointment with the consultant was a bit of a blur after the shock of her saying his life expectancy is approx 80 months, so we have
Tdg73
in
MPN Voice
19 hours ago
Decisions
Hello, I have HGSOC now grade 4 spread to liver abdomen and bowel and have just finished 6 months of weekly taxol with a week's break every 3 weeks. CT scan shows good result with nodules stable or have shrunk. I have been given a choice to continue taxol indefinitely or to watch and wait to have chemo
Hello, I have HGSOC now grade 4 spread to liver abdomen and bowel and have just finished 6 months of weekly taxol with a week's break every 3 weeks. CT scan shows good result with nodules stable or have shrunk. I have been given a choice to continue taxol indefinitely or to watch and wait to have chemo
Fizzgirl
in
My Ovacome
22 hours ago
Report: Ceylon Cinnamon Relieves Parkinson's Motor Impairment. Evidence Suggests Remedy of Underlying Disease (repost)
Image credit: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720887/pdf/nihms-1649509.pdf Can cinnamon spice down autoimmune diseases? This post includes both evidence from the medical literature and personal observation. It was originally posted in 2020 and had been deleted recently due to an unfortunate
Image credit: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720887/pdf/nihms-1649509.pdf Can cinnamon spice down autoimmune diseases? This post includes both evidence from the medical literature and personal observation. It was originally posted in 2020 and had been deleted recently due to an unfortunate
park_bear
in
Cure Parkinson's
7 days ago
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