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Staying on Ibrance & Anastrozole after 2 recurrences
I’ve been on Ibrance and Anastrozole for the last 6 years for metastatic endometrial cancer. I started out on the Ibrance125 mg and after a couple of years, had a problem recovering on the week off, so my dose was reduced to 100 mg. By spring this year, the counts could not recover on the week off,
I’ve been on Ibrance and Anastrozole for the last 6 years for metastatic endometrial cancer. I started out on the Ibrance125 mg and after a couple of years, had a problem recovering on the week off, so my dose was reduced to 100 mg. By spring this year, the counts could not recover on the week off,
Merma
in
SHARE Metastatic Breast Cancer
5 months ago
Hello friends. It's me again. Bone Biopsy + Dr. nonsense.
Ok, so I have not posted my situation for awhile because I was/am still waiting for tests. Quick review-Luminal A Hr Es+ 90-100% Pr+80-90%,ki67<10% HER2 neg(2+,sish neg) her2 low, I guess. This was the original in 2016. Had chemo, rads, anastrozle up to 2019 when dx mbc. Ibrance + fasoldex, then xeloda
Ok, so I have not posted my situation for awhile because I was/am still waiting for tests. Quick review-Luminal A Hr Es+ 90-100% Pr+80-90%,ki67<10% HER2 neg(2+,sish neg) her2 low, I guess. This was the original in 2016. Had chemo, rads, anastrozle up to 2019 when dx mbc. Ibrance + fasoldex, then xeloda
Hopeful4Cure
in
SHARE Metastatic Breast Cancer
5 months ago
NON SURGICAL OPTIONS?
Has any gone through successful or unsuccessful [u]
non-surgical treatments
[/u] with their breast cancer? [u]
Off-label drugs, diet change, hormone therapy, metabolic oncology
[/u], etc? Please share your story. This is all so sudden and shocking (as with most people's experience I'm
Has any gone through successful or unsuccessful [u]
non-surgical treatments
[/u] with their breast cancer? [u]
Off-label drugs, diet change, hormone therapy, metabolic oncology
[/u], etc? Please share your story. This is all so sudden and shocking (as with most people's experience I'm
jawsbar75
in
SHARE Breast Cancer Support
10 months ago
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Update – surgery tomorrow, then on to Xeloda
Hello all – hope that the new year is finding you all on a good journey to healing and wellness. I unfortunately have been in and out of the hospital for 21 days with seven new MRIs as they are trying to discover the root cause of my back pain and inability to walk. In addition to the extensive bone
Hello all – hope that the new year is finding you all on a good journey to healing and wellness. I unfortunately have been in and out of the hospital for 21 days with seven new MRIs as they are trying to discover the root cause of my back pain and inability to walk. In addition to the extensive bone
Saltandlight
in
SHARE Metastatic Breast Cancer
5 months ago
NMSC- Non melanoma Skin cancer
NMSC - Non-melanoma Skin Cancer is globally the most common form of cancer. 1 in 4 UK males and 1 in 5 UK females will be diagnosed with NMSC in their lifetime - and if diagnosed once, you could have many more! Learning how to spot the early signs and symptoms is vital, as if detected, diagnosed and
NMSC - Non-melanoma Skin Cancer is globally the most common form of cancer. 1 in 4 UK males and 1 in 5 UK females will be diagnosed with NMSC in their lifetime - and if diagnosed once, you could have many more! Learning how to spot the early signs and symptoms is vital, as if detected, diagnosed and
SkcinHQ
Partner
in
Skin Cancer UK
6 months ago
bumped up moms scans
So I had shared that her markers had went up last week. When she had the progression in July she also had a plural effusion. Which she’s had drained only twice in 6 months. But her ribs have started being sore. So she goes into tomorrow for ultra sound to see if the fluid has built back up. So her
So I had shared that her markers had went up last week. When she had the progression in July she also had a plural effusion. Which she’s had drained only twice in 6 months. But her ribs have started being sore. So she goes into tomorrow for ultra sound to see if the fluid has built back up. So her
Flower1513
in
SHARE Metastatic Breast Cancer
5 months ago
Pain all over
Hello everyone hope you all had a good holiday. As some might know I had a brain tumor removed in 2019. I've had some problems but I'm wounded if it could have triggered fibromyalgia. With all the pain and problems but I'm afraid that I'll sound like a nut job if I ask my doctor.????
Hello everyone hope you all had a good holiday. As some might know I had a brain tumor removed in 2019. I've had some problems but I'm wounded if it could have triggered fibromyalgia. With all the pain and problems but I'm afraid that I'll sound like a nut job if I ask my doctor.????
Duchess39
in
Headway
6 months ago
Verzenio Monotherapy
I'm wondering if anyone on here is on Verzenio monotherapy. That is just Verzenio,not in combo with anything. I take 200mg twice daily. I began this just over a month ago and wondering if anyone has been on this protocol and seen it help. To give a background. I was diagnosed first 27 years ago. Stage
I'm wondering if anyone on here is on Verzenio monotherapy. That is just Verzenio,not in combo with anything. I take 200mg twice daily. I began this just over a month ago and wondering if anyone has been on this protocol and seen it help. To give a background. I was diagnosed first 27 years ago. Stage
caw517
in
SHARE Metastatic Breast Cancer
5 months ago
tumor marker question
Hello!! My mom had her tumor markers checked on Oct 17th 2023. They were 333 that’s when we found out her anfintor wasn’t working 2nd line treatment. She was on it about 6 weeks. Around Nov 15th she started xeloda so for about a month she was on nothing! She’s did 3 round of xeloda now. Her oncologist
Hello!! My mom had her tumor markers checked on Oct 17th 2023. They were 333 that’s when we found out her anfintor wasn’t working 2nd line treatment. She was on it about 6 weeks. Around Nov 15th she started xeloda so for about a month she was on nothing! She’s did 3 round of xeloda now. Her oncologist
Flower1513
in
SHARE Metastatic Breast Cancer
5 months ago
Teva - short supply
Happy New Year everyone , Is anyone else finding it difficult to get 100mcg and 50 mcg Teva Levothyroxine ? I had a thyroidectomy 6 years ago and have been really well on this medication. I changed to Accent because independent pharmacist unable to source Teva . I was really unwell for 7 days on Accent
Happy New Year everyone , Is anyone else finding it difficult to get 100mcg and 50 mcg Teva Levothyroxine ? I had a thyroidectomy 6 years ago and have been really well on this medication. I changed to Accent because independent pharmacist unable to source Teva . I was really unwell for 7 days on Accent
CheerfulCharlie
in
Thyroid UK
6 months ago
18 years ago today!
🧡 18 years ago today we said our final farewell to our beautiful mother, best friend, devoted wife and grandmother Karen Clifford (represented by the KC in SKCIN) following her courageous battle to melanoma. The devastation caused by her loss, made us determined to ensure her untimely death was not
🧡 18 years ago today we said our final farewell to our beautiful mother, best friend, devoted wife and grandmother Karen Clifford (represented by the KC in SKCIN) following her courageous battle to melanoma. The devastation caused by her loss, made us determined to ensure her untimely death was not
SkcinHQ
Partner
in
Skin Cancer UK
6 months ago
Newly diagnosed Stage 4
hello I’m new here I’m very happy to be there. I read a lot of stories about people with Metastase breast cancer. Thank you so much you give me a lot of hope. Thanks again I’m 33, Diagnosed in 2022 stage 3 DIC, 5/19 axillary lymph node involved, ER+, HER -. I did 5months chemo, double mastectomy,
hello I’m new here I’m very happy to be there. I read a lot of stories about people with Metastase breast cancer. Thank you so much you give me a lot of hope. Thanks again I’m 33, Diagnosed in 2022 stage 3 DIC, 5/19 axillary lymph node involved, ER+, HER -. I did 5months chemo, double mastectomy,
life2990
in
SHARE Metastatic Breast Cancer
6 months ago
Peer Support/Breast Cancer Patient Helpline Volunteer
We are looking for a few good people who are willing to receive and return calls of individuals who has been diagnosed with early stage breast cancer. If you are interested, please contact me for more information @ kadams@sharecancersupport.org. Karen Adams Breast Cancer Support Manager
We are looking for a few good people who are willing to receive and return calls of individuals who has been diagnosed with early stage breast cancer. If you are interested, please contact me for more information @ kadams@sharecancersupport.org. Karen Adams Breast Cancer Support Manager
Adamskd1
in
SHARE Breast Cancer Support
10 months ago
Synthetic Hormones, Chemo & Radiotherapy
Hello, I am 60 years old, female,in the U.K., have had Primary Myelofibrosis for 20 years, treated with Aspirin & HU until recently, now switched to Anagrelide. I have recently been diagnosed with breast cancer, due to have lumpectomy next month, then there will be decisions to make about further treatments
Hello, I am 60 years old, female,in the U.K., have had Primary Myelofibrosis for 20 years, treated with Aspirin & HU until recently, now switched to Anagrelide. I have recently been diagnosed with breast cancer, due to have lumpectomy next month, then there will be decisions to make about further treatments
CraftySpider
in
MPN Voice
10 months ago
Very promising: PIP Polyspecific Integrin-Binding Peptide, a novel and very flexible platform
Basically, they have developed a technology that can simultaneously bind to different "proteins" expressed by cancers. This means a wider specificity. One cancer mutation could express for example KRAS 12C and another KRAS 12D (just an example using terms and mutation I know!) and the chemo drug would
Basically, they have developed a technology that can simultaneously bind to different "proteins" expressed by cancers. This means a wider specificity. One cancer mutation could express for example KRAS 12C and another KRAS 12D (just an example using terms and mutation I know!) and the chemo drug would
Maxone73
in
Advanced Prostate Cancer
3 hours ago
Guided bacteria, 100% effective in preclinical trials
well, I am citing... "With a 100% remission rate and no meaningful side effects in all the subjects of the company's preclinical trials, this technology is conceived to address all solid tumors, representing 90% of cancer and 89% of deaths." Even 50% of that result in humans would be amazing! https
well, I am citing... "With a 100% remission rate and no meaningful side effects in all the subjects of the company's preclinical trials, this technology is conceived to address all solid tumors, representing 90% of cancer and 89% of deaths." Even 50% of that result in humans would be amazing! https
Maxone73
in
Advanced Prostate Cancer
3 hours ago
Only mouse study, but interesting research on microbiome using astragaloside and scorpion venom
Astragaloside IV-PESV inhibits prostate cancer tumor growth by restoring gut microbiota and microbial metabolic homeostasis via the AGE-RAGE pathwayXujun You, Junfeng Qiu, Qixin Li, Qing Zhang, Wen Sheng, Yiguo Cao, Wei Fu BMC cancer 24 (1), 472, 2024 Background Prostate cancer (PCa) is becoming the
Astragaloside IV-PESV inhibits prostate cancer tumor growth by restoring gut microbiota and microbial metabolic homeostasis via the AGE-RAGE pathwayXujun You, Junfeng Qiu, Qixin Li, Qing Zhang, Wen Sheng, Yiguo Cao, Wei Fu BMC cancer 24 (1), 472, 2024 Background Prostate cancer (PCa) is becoming the
Graham49
in
Advanced Prostate Cancer
7 hours ago
Consider the options?
Post total hysterectomy, etc., one cycle of carboplatin (couldn't tolerate paclitaxel) and now on Avastin i/v and Olaparib. CA 9, which is fantastic. Side effects are just destroying me. I am 80, the Olaparib goes through to mid June 2026 and the Avastin finishes at the end of this year. Oncologist
Post total hysterectomy, etc., one cycle of carboplatin (couldn't tolerate paclitaxel) and now on Avastin i/v and Olaparib. CA 9, which is fantastic. Side effects are just destroying me. I am 80, the Olaparib goes through to mid June 2026 and the Avastin finishes at the end of this year. Oncologist
Pawpaw22
in
My Ovacome
10 hours ago
slight CEA Elevation
hi everyone- my father has MBC and is currently on Lynparza / Olaparib to target the BRCA2 gene mutation. He has been on it for 9 months and had a scan that showed complete control over his breast cancer on May 21st (not too long ago at all). The only thing that “lit up” on the scan was his Prostate
hi everyone- my father has MBC and is currently on Lynparza / Olaparib to target the BRCA2 gene mutation. He has been on it for 9 months and had a scan that showed complete control over his breast cancer on May 21st (not too long ago at all). The only thing that “lit up” on the scan was his Prostate
Jenniferp2122
in
SHARE Metastatic Breast Cancer
11 hours ago
Be careful: Pluvicto controversy, dammit!
not saying that it does not work, in fact for some patients it is simply fantastic, but still...they have damaged their reputation with patients https://www.nature.com/articles/s44276-024-00065-7 The PSMAfore and VISION trials for Lutetium-177 PSMA-617 in prostate cancer exhibit design flaws that bias
not saying that it does not work, in fact for some patients it is simply fantastic, but still...they have damaged their reputation with patients https://www.nature.com/articles/s44276-024-00065-7 The PSMAfore and VISION trials for Lutetium-177 PSMA-617 in prostate cancer exhibit design flaws that bias
Maxone73
in
Advanced Prostate Cancer
12 hours ago
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