Experiences with

Breast tumours

Using a low dose of the epigenetic therapy drug decitabine, which is currently used to treat some blood cancers, the researchers significantly suppressed the growth of endocrine resistant breast tumours in mice and increased survival time by 90%.

I was looking up wether morphine can activate mast cells and found the following: “We demonstrate that morphine does not influence cancer initiation, but it stimulates the progression of spontaneously developed breast tumours and shortens the survival of tumour-bearing mice.

I had a face to face meeting with the Health Board CEO. To start with he quoted the Patient Experience answers to my concerns but I soon stopped that showing photographic evidence that they were lying. As the meeting progressed he became very quiet and obviously shaken. His PA took a lot of notes and

Hi all, I had a bilateral mastectomy 4 years ago and have had a recurrence. I've had surgery to remove the involved lymph nodes, have been on monthly Fulvestrant injections and take Kisqali. I'm going to be starting 6 weeks of radiation by the end of the month and I am totally petrified of it

Hi everyone, I have started taxol three weeks ago. I was supposed to start Avastin at the same time but I had dental work done and it’s on hold until November. I’m stage 4B ovarian and I’m really struggling with the taxol . I’m really weak and fatigued. Anyone any experience of this . thanks xx

Today I found out that I have a second breast cancer. I was diagnosed with MBC in 2019 (ER/PR- Her2+)and recently had a mammogram that showed a tumor. The biopsy results show a second breast cancer(ER/PR+ Her2+). In the next two weeks I have a PET scan and Brain MRI. Is there anyone else out there

Hi- I have been on Tamoxifen for five years- because I had a history of UTIs when I was much younger and was worried about the effects of tamoxifen on bladder and vagina I used local low dose estrogen -Estring or Vagifem depending on what was available - apparently this very localized dose doesn’t affect

I have been on tamoxifen for 7 and a half years now but for some reason for the last 4-5 years I get lots of UTI’s which are unpleasant and painful. My GP and oncologist say it is not related to tamoxifen but I wonder if it is as it blocks the estrogen and decreased estrogen can lead to bladder and

Hello, Just feeling down in the dumps after seeing my oncologist. He has never been positive about my outlook but I was feeling quite positive after responding well to surgery and chemo. But got a reality check now that CA125 has risen to 125. What doctors would you recommend for a second opinion?

Electrolyte’s imbalance role in atrial fibrillation: Pharmacological management https://arrhythmia.biomedcentral.com/articles/10.1186/s42444-022-00065-z and Elimination of cardiac arrhythmias using oral taurine with l-arginine with case histories: Hypothesis for nitric oxide stabilization of the sinus

hello, I’m in the UK. Have been on tamoxifen for 6 years after mastectomy, chemo and radiotherapy. I've still not had my 5th year follow up with the oncologist, when I call them they just say “sorry no capacity”. Anyway long story short i came off tamoxifen about 3 months ago as i didn't want to just

I was diagnosed with endometroid 3B & synchronous 1A endometrial in 2021 ER+ negative for genetic for genetic mutations My CA125 rose in 8/2023, pet showed lymph node in left supraclavicular clavicle and spot in vaginal cuff which ended up being scar tissue had biopsy same sub type my CA125 rose from

As so often, more research needed. But worth at least a quick look if you are interested. [i]Relationship between serum vitamin D levels and thyroid- and parathyroid-related diseases: a Mendelian randomisation study[/i] [i][/i] [i]Published online by Cambridge University Press: 30 September

Hi! This has been a very difficult year for me to say the least ,but I can say this…. Wow! I never knew I was such a Strong, Determined Warrior. I was diagnosed in February 2024 with invasive breast cancer just 4 months after my cleared mammogram. I accidentally found the 2 tumors. Had a mastectomy April

Hi! This has been a very difficult year for me to say the least ,but I can say this…. Wow! I never knew I was such a Strong, Determined Warrior. I was diagnosed in February 2024 with invasive breast cancer just 4 months after my cleared mammogram. I accidentally found the 2 tumors. Had a mastectomy April

Good morning ladies My wife was was diagnosed with HGOC in 2020. She received the usual treatment Chemo including debunking she's never been NED. Earlier this year it was found the disease had spread to supraclavicular nodes and she was advised watch and wait until they progressed which unfortunately

I was diagnosed with sll in july 24 and started acalabrutinib in late August. I saw my oncologist once when first diagnosed and have had two follow up visits for bloodwork and was seen both times by his physicians assistant who mostly just asked about any issues or side effects i may be having. I asked

I have a question for tamoxifen users. Not a big deal but I am curious. I am 76 and have been on tamoxifen for a year and a half. I have gray hair - quite long. The hair is thinning but my curiosity is about my hair darkening. It is turning a dark brunette. Just seems kind of weird. Anyone else had that

I had a partial thyroidectomy (left removed) in April 2023. I am on 50mg levothyroxine but I am still not feeling right. I am having trouble regulating my temperature, my hair has tinned a lot. I am tired, ache, have put on weight and feel miserable. Keep being told by GP that my TSH is in normal range

Hi everyone, I'm a high school student working on an exciting project to develop an app that provides personalized medication reviews for Tamoxifen. This app will help users understand how Tamoxifen works for people with similar demographics (gender, ethnicity, weight, age). Why Your Input Matters