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Epigenetic therapy (decitabine) shows promise for endocrine-resistant breast cancer
Using a low dose of the epigenetic therapy drug decitabine, which is currently used to treat some blood cancers, the researchers significantly suppressed the growth of endocrine resistant
breast
tumours
in mice and increased survival time by 90%.
Using a low dose of the epigenetic therapy drug decitabine, which is currently used to treat some blood cancers, the researchers significantly suppressed the growth of endocrine resistant
breast
tumours
in mice and increased survival time by 90%.
Split
in
SHARE Metastatic Breast Cancer
4 months ago
Could Morphine accelerate prostate cancer progression?
I was looking up wether morphine can activate mast cells and found the following: “We demonstrate that morphine does not influence cancer initiation, but it stimulates the progression of spontaneously developed
breast
tumours
and shortens the survival of tumour-bearing mice.
I was looking up wether morphine can activate mast cells and found the following: “We demonstrate that morphine does not influence cancer initiation, but it stimulates the progression of spontaneously developed
breast
tumours
and shortens the survival of tumour-bearing mice.
markrichardson
in
Advanced Prostate Cancer
7 months ago
Trying to follow a healthy lifestyle while on long term drug therapy
So finding my lump and realising I had Breast Cancer has taken me on a strange journey. I'm a healthy active 75 year old carer for my darling hubby. I am starting month 6 of Letrozole, have had 1 Ibandronic acid treatment and have just been taken off my Abemeciclib tablets after almost 8 weeks as
So finding my lump and realising I had Breast Cancer has taken me on a strange journey. I'm a healthy active 75 year old carer for my darling hubby. I am starting month 6 of Letrozole, have had 1 Ibandronic acid treatment and have just been taken off my Abemeciclib tablets after almost 8 weeks as
wackier
in
SHARE Breast Cancer Support
2 days ago
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I’m taking tamoxifen for breast cancer. It had impacted thyroid levels in the autumn but I only adjusted by a little. Latest test was tsh 5.17 and t4 17 (not taken that day) on 125 for 3 days a week and 100 for 4 days a week. Obviously I’m not very with it now. I think it has been like this for
I’m taking tamoxifen for breast cancer. It had impacted thyroid levels in the autumn but I only adjusted by a little. Latest test was tsh 5.17 and t4 17 (not taken that day) on 125 for 3 days a week and 100 for 4 days a week. Obviously I’m not very with it now. I think it has been like this for
haggisplant
in
Thyroid UK
7 days ago
Clinical trial update
Trial Drugs: Inavolisib and Giredestrant. Today was my second set of scans (every 8 weeks) and the results of the chest CT and Bone scans were great, nothing new, all stable and NED in lungs. The abdomen CT showed slight increase in the size of my liver lesions. I am ER+, HER2 low +1, PR-, AR+, with
Trial Drugs: Inavolisib and Giredestrant. Today was my second set of scans (every 8 weeks) and the results of the chest CT and Bone scans were great, nothing new, all stable and NED in lungs. The abdomen CT showed slight increase in the size of my liver lesions. I am ER+, HER2 low +1, PR-, AR+, with
Trissh
in
SHARE Metastatic Breast Cancer
10 days ago
Letrozole
I saw the oncologist yesterday to discuss radiotherapy and hormone therapy.The plan for radiotherapy is on hold ATM because I have an ongoing issue with a seroma on the breast and underarm. During the meeting she said she would give me a prescription for Letrozole, I told her I wasn't happy to start
I saw the oncologist yesterday to discuss radiotherapy and hormone therapy.The plan for radiotherapy is on hold ATM because I have an ongoing issue with a seroma on the breast and underarm. During the meeting she said she would give me a prescription for Letrozole, I told her I wasn't happy to start
LindaLittleBear
in
My Breast Cancer Community
14 days ago
Oil of Evening Primrose
I had a lumpectomy last May. It was a small ductal carcinoma which was invasive. I went on to have Radiotherapy and started a five year course of Letrozole. I developed bad joint pain and I had a month off to see if the Letrozole was the culprit. It was better but not gone. The oncology nurse suggested
I had a lumpectomy last May. It was a small ductal carcinoma which was invasive. I went on to have Radiotherapy and started a five year course of Letrozole. I developed bad joint pain and I had a month off to see if the Letrozole was the culprit. It was better but not gone. The oncology nurse suggested
Tabbycat64
in
My Breast Cancer Community
15 days ago
Question about tumor markers
Hi there, happy spring to all!! My Mom’s been doing well with trial med in combination with Faslodex monthly. Her blood work has been normal with good liver function. Her tumor marker test (the CA 15-3) test showed in the 350 range. I’m not sure it’s ever been that high but it was in the 150 range
Hi there, happy spring to all!! My Mom’s been doing well with trial med in combination with Faslodex monthly. Her blood work has been normal with good liver function. Her tumor marker test (the CA 15-3) test showed in the 350 range. I’m not sure it’s ever been that high but it was in the 150 range
Pups2Cute
in
SHARE Metastatic Breast Cancer
16 days ago
Exemestane and Afinitor
Hi everyone I just completed 1 month of Truqap. I had to stop treatment due to a cough and a horrible rash. I had to stay in the ER for 24 hours due to the rash. I am now moving on to Exemestane and Afinitor. I would so appreciate any experience that anyone has had on these 2 meds. I’m mostly interested
Hi everyone I just completed 1 month of Truqap. I had to stop treatment due to a cough and a horrible rash. I had to stay in the ER for 24 hours due to the rash. I am now moving on to Exemestane and Afinitor. I would so appreciate any experience that anyone has had on these 2 meds. I’m mostly interested
Jhshl512
in
SHARE Metastatic Breast Cancer
17 days ago
Breast dimpling post Lumpectomy?
Hi there! Anyone notice breast dimpling after lumpectomy? It has been 6 months after my surgery and I’m seeing 2 distinct dimples showing in the surgery area. I’m thinking it could be from the scar tissue?
Hi there! Anyone notice breast dimpling after lumpectomy? It has been 6 months after my surgery and I’m seeing 2 distinct dimples showing in the surgery area. I’m thinking it could be from the scar tissue?
NeenJah
in
SHARE Breast Cancer Support
18 days ago
Lizzietish
'Benign' cyst removed and has turned out to be in my bones and lungs and obviously in my skin. ER, PR + and HER-. All my research tells me I am doomed as skin mets are meant to be terminal?????? My oncology team were so upbeat, started on Letrozole and Ribociclib and Denosumab. I have no symptoms
'Benign' cyst removed and has turned out to be in my bones and lungs and obviously in my skin. ER, PR + and HER-. All my research tells me I am doomed as skin mets are meant to be terminal?????? My oncology team were so upbeat, started on Letrozole and Ribociclib and Denosumab. I have no symptoms
Lizzietosh
in
SHARE Metastatic Breast Cancer
19 days ago
Radiation for cancer other than thyroid.
Does radiation treatment for breast cancer affect thyroid medications? Does dose need to be adjusted during or after treatment?
Does radiation treatment for breast cancer affect thyroid medications? Does dose need to be adjusted during or after treatment?
raglansleeve
in
Thyroid UK
26 days ago
Acute Liver Failure Diagnosis
On Tuesday, I finally received the long awaited Truqap. I was told to hold off beginning treatment and to bring the medicine to the oncologist's off on Thursday. The oncologist took one look at me and dropped her jaw in awe of my yellow skin color, which I could not see, then shipped me off to the
On Tuesday, I finally received the long awaited Truqap. I was told to hold off beginning treatment and to bring the medicine to the oncologist's off on Thursday. The oncologist took one look at me and dropped her jaw in awe of my yellow skin color, which I could not see, then shipped me off to the
jersey-jazz
in
SHARE Metastatic Breast Cancer
1 month ago
TP53 Testing
Good afternoon. My oncologist called me last month to tell me that my FISH test indicated that I had Trisomy 12. He went on to say “You should feel lucky that you don’t have TP53.” I watched this excellent video yesterday. The doctors discussed the importance of having the separate TP53 test with FISH
Good afternoon. My oncologist called me last month to tell me that my FISH test indicated that I had Trisomy 12. He went on to say “You should feel lucky that you don’t have TP53.” I watched this excellent video yesterday. The doctors discussed the importance of having the separate TP53 test with FISH
EastBayDad
in
CLL Support
1 month ago
Hormonal therapy ?
Hi, I was diagnosed with extended DCIS with ER+, PR+.I had a total mastectomy with a diep flap 2 weeks ago, My surgeon referred me to medical oncology for hormonal therapy. I am curious do I still need hormonal therapy as I already had a mastectomy, as far as cancer recurrence and preventing cancer
Hi, I was diagnosed with extended DCIS with ER+, PR+.I had a total mastectomy with a diep flap 2 weeks ago, My surgeon referred me to medical oncology for hormonal therapy. I am curious do I still need hormonal therapy as I already had a mastectomy, as far as cancer recurrence and preventing cancer
Rarlod
in
SHARE Breast Cancer Support
1 month ago
My mom just got diagnosed with CLL at 59 - we have questions - thank you for all the support on my previous post!
1. We live in Southern California - does anyone know a great specialist near by? 2. Her ABSOLUTE LYMPHOCYTES are 9533 - does anyone have similar numbers but they have increased 24% from a month ago when they were at 7732?? Is this alarming? 3. Her IGHV test came back at 6.87% - what does that mean?
1. We live in Southern California - does anyone know a great specialist near by? 2. Her ABSOLUTE LYMPHOCYTES are 9533 - does anyone have similar numbers but they have increased 24% from a month ago when they were at 7732?? Is this alarming? 3. Her IGHV test came back at 6.87% - what does that mean?
Chickenoodlesoup
in
CLL Support
2 months ago
Tumors Shrinking!
Brave Bold Cancer Thrivers, I am ER+, HER2 negative and I, finally after four months, have an oncologist I just love (she's so thorough with everything and very kind and caring), and my treatment is working! I am on Ibrance and letrozole and in only 2 months majority of the tumors have shrunk in half
Brave Bold Cancer Thrivers, I am ER+, HER2 negative and I, finally after four months, have an oncologist I just love (she's so thorough with everything and very kind and caring), and my treatment is working! I am on Ibrance and letrozole and in only 2 months majority of the tumors have shrunk in half
monkeygirl62
in
SHARE Metastatic Breast Cancer
2 months ago
Letrozole weight gain
Hi, I am posting this on behalf of my mum who suffered from breast cancer 2022-2023 she went through surgery, chemo and radiation and she is now clear of breast cancer. however she has to take Letrozole for 5 years and she is really struggling with the side effects she has put on a lot of weight since
Hi, I am posting this on behalf of my mum who suffered from breast cancer 2022-2023 she went through surgery, chemo and radiation and she is now clear of breast cancer. however she has to take Letrozole for 5 years and she is really struggling with the side effects she has put on a lot of weight since
MyStar86
in
My Breast Cancer Community
2 months ago
Hi everyone, I was diagnosed with Breast Cancer. ER7, PGR4, HER2 neg (and NPI 3.44 what ever this is).
I discovered a lump on Christmas Day, was seen at the hospital on the 10th of January. January 23rd the lump was removed along with 4 lymph nodes. My question is I am on Anastrazole 1mg , Levothyroxine 25mg (thyroid decided to pack in) and Atorovastatin 40mg. Can I take any of these pills at the same
I discovered a lump on Christmas Day, was seen at the hospital on the 10th of January. January 23rd the lump was removed along with 4 lymph nodes. My question is I am on Anastrazole 1mg , Levothyroxine 25mg (thyroid decided to pack in) and Atorovastatin 40mg. Can I take any of these pills at the same
sas65
in
SHARE Breast Cancer Support
2 months ago
Niraparib
I was diagnosed with Stage 3c high grade serous ovarian cancer in June 2023 which had spread to omentum and peritoneal lining. I had ascites which was drained twice and have developed a pleural effusion. I had the 3xchemo and debulking surgery then 3 more chemo. Finished treatment on Dec 23. ca-125
I was diagnosed with Stage 3c high grade serous ovarian cancer in June 2023 which had spread to omentum and peritoneal lining. I had ascites which was drained twice and have developed a pleural effusion. I had the 3xchemo and debulking surgery then 3 more chemo. Finished treatment on Dec 23. ca-125
Berryporridgr
in
My Ovacome
2 months ago
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