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Neuroprotective effect of rapamycin against Parkinson's disease in mice - 2018 https://pubmed.ncbi.nlm.nih.gov/30693687/
Conclusions: Rapamycin inhibits the activation of mTOR pathway, which contributes to protect against the loss of dopaminergic neurons and provide behavioral improvements in mice with Parkinson's disease. These results are partially related to the ability of rapamycin in inducing autophagy and reducing
Conclusions: Rapamycin inhibits the activation of mTOR pathway, which contributes to protect against the loss of dopaminergic neurons and provide behavioral improvements in mice with Parkinson's disease. These results are partially related to the ability of rapamycin in inducing autophagy and reducing
Bolt_Upright
in
Cure Parkinson's
3 years ago
Medication and second pregnancy
Hi, I was hoping to get some advice from women who have had PPP and gone on to have a second pregnancy. I had severe PPP with my first born, developing only a couple of days after birth. I was admitted into an MBU for 3 months. Responded quickly to treatment on Olanzapine. Several tumultuous years followed
Hi, I was hoping to get some advice from women who have had PPP and gone on to have a second pregnancy. I had severe PPP with my first born, developing only a couple of days after birth. I was admitted into an MBU for 3 months. Responded quickly to treatment on Olanzapine. Several tumultuous years followed
Orea
in
Action on Postpartum Psychosis
3 years ago
Experience with zoloft? Help :)
hey everyone, i booked my 2nd appointment since 2 years, i definitely needed it as i have been getting into alot of pressure and my mental health has been taking a hit with new symptoms and annoyances. My dr explained to me how he is seeing symptoms and indications of depression not just anxiety, but
hey everyone, i booked my 2nd appointment since 2 years, i definitely needed it as i have been getting into alot of pressure and my mental health has been taking a hit with new symptoms and annoyances. My dr explained to me how he is seeing symptoms and indications of depression not just anxiety, but
Kevin160
in
Anxiety and Depression Support
2 years ago
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How do you quit drinking
I drink alcohol 0-1 times per week socially with friends. My New Years resolution was to not black out for the year, but I screwed that one up last night. Edit: Usually I’m fine just having a couple. But maybe once every 6 months after having a couple I keep going and I black out by the end of the night
I drink alcohol 0-1 times per week socially with friends. My New Years resolution was to not black out for the year, but I screwed that one up last night. Edit: Usually I’m fine just having a couple. But maybe once every 6 months after having a couple I keep going and I black out by the end of the night
Poodlefanforlife
in
Anxiety and Depression Support
2 years ago
New to grout
Hey all, am new to this forum Suffer with major depressive disorder with anxiety and recently went from 150 mg to 225mg of Effexor XR
Hey all, am new to this forum Suffer with major depressive disorder with anxiety and recently went from 150 mg to 225mg of Effexor XR
Ange71
in
Anxiety Support
2 years ago
Sulforaphane, NAC, H2O2, and the Circadian Rhythm
I have no answers. Just questions. Questions about Sulforaphane, NAC, and their effects on the Circadian Rhythm.I recently stopped taking my Broccoli Sprout Tea as it boosts NRF2, and boosting NRF2 may amplify the Circadian Rhythm, but if you want to amplify the Circadian Rhythm you probably want to
I have no answers. Just questions. Questions about Sulforaphane, NAC, and their effects on the Circadian Rhythm.I recently stopped taking my Broccoli Sprout Tea as it boosts NRF2, and boosting NRF2 may amplify the Circadian Rhythm, but if you want to amplify the Circadian Rhythm you probably want to
Bolt_Upright
in
Cure Parkinson's
3 years ago
Doxazosin
Hey, Is anyone here taking doxazosin for their PTSD? If so what dose and has it had a positive effect?
Hey, Is anyone here taking doxazosin for their PTSD? If so what dose and has it had a positive effect?
Titch1908
in
Heal My PTSD
2 years ago
Follow Up - (Post Ablation Travel)
I'm writing the follow up on a post I did about a month ago regarding an upcoming ablation procedure. If you recall, my concern was about traveling from Orlando to Johns Hopkins Hospital in Baltimore … I wanted to get feedback concerning how long I should stay before returning on a flight home and about
I'm writing the follow up on a post I did about a month ago regarding an upcoming ablation procedure. If you recall, my concern was about traveling from Orlando to Johns Hopkins Hospital in Baltimore … I wanted to get feedback concerning how long I should stay before returning on a flight home and about
MJZaw
in
AF Association
2 years ago
Palpitations at night
Does anyone have heart palpitations that keep them awake when they go to bed? Breathing exercises don't seem to help. I've joined walking groups to walk during the day and use up some of the adrenalin, but it doesn't seem to help. Any advice would be appreciated.
Does anyone have heart palpitations that keep them awake when they go to bed? Breathing exercises don't seem to help. I've joined walking groups to walk during the day and use up some of the adrenalin, but it doesn't seem to help. Any advice would be appreciated.
bugswhiskers
in
AF Association
2 years ago
Return of the RLS
Hello again fellow sufferers. Well I've lost track of where my journey is at. I paid to see a private neurologist who prescribed pregabalin 75mg no as gp increased it and 3 clonazapam early evening on his advice. At first it was amazing no symptoms slept right through no twitching or thrashing about
Hello again fellow sufferers. Well I've lost track of where my journey is at. I paid to see a private neurologist who prescribed pregabalin 75mg no as gp increased it and 3 clonazapam early evening on his advice. At first it was amazing no symptoms slept right through no twitching or thrashing about
Netball-50
in
Restless Legs Syndrome
3 years ago
Diagnosed with Polyhydramnios at 27 weeks
Hi there, I went for a private 3D scan at 27+3 and they said my amniotic was 9cm (the most it should be is 8cm) and that I should call my midwife. Other than that the baby looked great and healthy albeit a bit bigger than average. The midwives got me in for an extra scan with them today and confirmed
Hi there, I went for a private 3D scan at 27+3 and they said my amniotic was 9cm (the most it should be is 8cm) and that I should call my midwife. Other than that the baby looked great and healthy albeit a bit bigger than average. The midwives got me in for an extra scan with them today and confirmed
PurpleCloud1
in
Pregnancy and Parenting Support
2 years ago
Worn out!
I'm exhausted...Worn out. Anxiety and PTSD management is a full-time gig. Can anybody relate?
I'm exhausted...Worn out. Anxiety and PTSD management is a full-time gig. Can anybody relate?
mrdrummer51
in
Anxiety and Depression Support
2 years ago
repetitive Transcranial Magnetic Stimulation - an update
I concluded repetitive Transcranial Magnetic Stimulation (rTMS) therapy just over two months ago. Unfortunately it doesn’t appear to have been effective for my Periodic Limb Movement Disorder (PLMD). I had 27 consecutive sessions (2 were high frequency, the remaining 25 were low frequency pulses delivered
I concluded repetitive Transcranial Magnetic Stimulation (rTMS) therapy just over two months ago. Unfortunately it doesn’t appear to have been effective for my Periodic Limb Movement Disorder (PLMD). I had 27 consecutive sessions (2 were high frequency, the remaining 25 were low frequency pulses delivered
Hidden
in
Restless Legs Syndrome
3 years ago
Trying to get off Sinemet
Still stuck on Sinemet (100mg levidopa/25mg carbidopa) which augmented causing severe muscle rigidity along with the worsening RLS convulsions. It was originally prescribed over 2 years ago to reduce potential damages to 4th spinal surgery. No one realized it would be so difficult to stop. I tapered
Still stuck on Sinemet (100mg levidopa/25mg carbidopa) which augmented causing severe muscle rigidity along with the worsening RLS convulsions. It was originally prescribed over 2 years ago to reduce potential damages to 4th spinal surgery. No one realized it would be so difficult to stop. I tapered
betternowman
in
Restless Legs Syndrome
3 years ago
Daughter rarely goes out of the house
My daughter (now 21) suffers with ASD and ADHD. Both diagnosis are fairly recent (last two years). She rarely leaves the house except to go to do her course which is twice a week. She has no interest in shopping so I can’t suggest that. We have a little dog but she won’t walk with me as she says I walk
My daughter (now 21) suffers with ASD and ADHD. Both diagnosis are fairly recent (last two years). She rarely leaves the house except to go to do her course which is twice a week. She has no interest in shopping so I can’t suggest that. We have a little dog but she won’t walk with me as she says I walk
FirstCoffee
in
Autism Support
2 years ago
Increasing Lexapro
I started taking lexapro three days ago at 5mg. The side effects of increased anxiousness really hit me today and tonight I had a panic attack and couldn’t sleep. My doctor wants me to increase to the 10 mg today on day 4 but I am nervous with the side effects I already have that it will just worsen
I started taking lexapro three days ago at 5mg. The side effects of increased anxiousness really hit me today and tonight I had a panic attack and couldn’t sleep. My doctor wants me to increase to the 10 mg today on day 4 but I am nervous with the side effects I already have that it will just worsen
BlueVibes
in
Anxiety and Depression Support
3 years ago
Eye surgery
I had eye surgery this past Tuesday for a retinal detachment. I have never had any problems with my eyes. Now I'm healing and having anxiety because I can't see out of my right eye yet. In freaking out thinking will this fix it? What if? What if? Has anyone else had eye surgery? Only respond with positives
I had eye surgery this past Tuesday for a retinal detachment. I have never had any problems with my eyes. Now I'm healing and having anxiety because I can't see out of my right eye yet. In freaking out thinking will this fix it? What if? What if? Has anyone else had eye surgery? Only respond with positives
Jstbcuz
in
Anxiety and Depression Support
3 years ago
Does it actually get better? I constantly need reassurance.
it’s just having anxiety makes me feel like I’m going crazy or something. I hate it, I want to cry about it but these damn antidepressants prevent me from feeling sad. Plus they also prescribed me anxiety meds and Im to anxious to take those with my Prozacs. Prozacs and Buspar??? Idk I’m just scared
it’s just having anxiety makes me feel like I’m going crazy or something. I hate it, I want to cry about it but these damn antidepressants prevent me from feeling sad. Plus they also prescribed me anxiety meds and Im to anxious to take those with my Prozacs. Prozacs and Buspar??? Idk I’m just scared
hopelessxsailor
in
Anxiety and Depression Support
3 years ago
I don't know what to do
I have been living in fear with my depression and anxiety. This week I screwed up big time. I have been between anxiety attacks and big lows of depression. Even writing this is taking a huge effort. My medication and coping skills are doing nothing. I just want to sleep.
I have been living in fear with my depression and anxiety. This week I screwed up big time. I have been between anxiety attacks and big lows of depression. Even writing this is taking a huge effort. My medication and coping skills are doing nothing. I just want to sleep.
jfrazee
in
Anxiety and Depression Support
3 years ago
EMDR Therapy
Has anyone tried EMDR to help trauma, anxiety, depression, PTSD? If so, how was your experience? I'm meeting with an EMDR therapist next week.
Has anyone tried EMDR to help trauma, anxiety, depression, PTSD? If so, how was your experience? I'm meeting with an EMDR therapist next week.
Tambourina
in
Anxiety and Depression Support
3 years ago
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