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"Undetectable"
We hear the term of "undetectable" with a psa of < .1 used so often. When I was first diagnosed and had an RALP I bought into the use of this theory. As the months clicked by and I was "undetectable" I was slowly gaining confidence and reassurance that this was true. Eight months later a .1 shattered
We hear the term of "undetectable" with a psa of < .1 used so often. When I was first diagnosed and had an RALP I bought into the use of this theory. As the months clicked by and I was "undetectable" I was slowly gaining confidence and reassurance that this was true. Eight months later a .1 shattered
Cyclingrealtor
in
Advanced Prostate Cancer
5 days ago
Advice on Zoladex?
I’m just looking for some advice regarding Zoladex, I was diagnosed with stage 3 Endo last November and my pain improved for maybe 3 months and then it’s back to how it was before, if not worse, I have an appointment upcoming with my endo specialist and I’ve recently had another MRI to check for missed
I’m just looking for some advice regarding Zoladex, I was diagnosed with stage 3 Endo last November and my pain improved for maybe 3 months and then it’s back to how it was before, if not worse, I have an appointment upcoming with my endo specialist and I’ve recently had another MRI to check for missed
Ps-endo
in
Endometriosis UK
5 days ago
help please osteoporosis at 48
hi there DEXA -3.7 and -3.5 Did have low bmi for many years no oestrogen Now on HRT What levels is ideal for hrt ? No one can tell me optimal range ? Ctx and 0.5 and Pn1p 106 All the rest is normal. T4 16 12 to 22 And t3 5.1 4.1 to 6.8 I’m only 48 . Can I improve it with jumping
hi there DEXA -3.7 and -3.5 Did have low bmi for many years no oestrogen Now on HRT What levels is ideal for hrt ? No one can tell me optimal range ? Ctx and 0.5 and Pn1p 106 All the rest is normal. T4 16 12 to 22 And t3 5.1 4.1 to 6.8 I’m only 48 . Can I improve it with jumping
Chouchou1234
in
Bone Health and Osteoporosis UK
5 days ago
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Brain Fog and ADT
Let's say, just stretching the imagination, that since testosterone is necessary for cognitive function, ADT, in lowering testosterone, lowers brain function to some degree. But in my case, ADT does not bring T to zero. I seem to have a T reading of around 12 or so in spite of the ADT. But some more
Let's say, just stretching the imagination, that since testosterone is necessary for cognitive function, ADT, in lowering testosterone, lowers brain function to some degree. But in my case, ADT does not bring T to zero. I seem to have a T reading of around 12 or so in spite of the ADT. But some more
NecessarilySo
in
Advanced Prostate Cancer
5 days ago
My discussion with chatGPT about senescence in PC induced by radiation and chemotherapy.
Q. Can adt cause senescence? A. Androgen deprivation therapy (ADT) primarily aims to reduce or block male hormones like testosterone that fuel prostate cancer growth. While ADT can significantly shrink tumors and lead to remission in many cases, it does not directly cause cellular senescence. However
Q. Can adt cause senescence? A. Androgen deprivation therapy (ADT) primarily aims to reduce or block male hormones like testosterone that fuel prostate cancer growth. While ADT can significantly shrink tumors and lead to remission in many cases, it does not directly cause cellular senescence. However
Seasid
in
Advanced Prostate Cancer
5 days ago
Lupron 12 vs. 18 Months
This is a follow-up to a post I made in January of this year. I was diagnosed at age 50, Gleason score 3+4 (10% pattern 4), highest PSA of 10.1, high-risk Decipher 0.84, PI, and some evidence of ECE. I was PSMA-negative. I started Lupron and was treated at UCLA in late October 2023 with SBRT on the MRIdian
This is a follow-up to a post I made in January of this year. I was diagnosed at age 50, Gleason score 3+4 (10% pattern 4), highest PSA of 10.1, high-risk Decipher 0.84, PI, and some evidence of ECE. I was PSMA-negative. I started Lupron and was treated at UCLA in late October 2023 with SBRT on the MRIdian
sptill72
in
Prostate Cancer Network
5 days ago
Advice on latest thyroid test
I am seeing GP tomorrow regarding latest blood tests. Currently take 125mg levothyroxine. TSH 0.32 (-65%) 0.35-4.94 T4 15.3 (62.38%) 9-19.1 T3 4.3 (52.78%) 2.4-6.0 TSH was flagged as Abnormal so GP will mention that - it was 1.08 in Feb and 1.25 last October (same ranges) but no T4 or T3 tested.
I am seeing GP tomorrow regarding latest blood tests. Currently take 125mg levothyroxine. TSH 0.32 (-65%) 0.35-4.94 T4 15.3 (62.38%) 9-19.1 T3 4.3 (52.78%) 2.4-6.0 TSH was flagged as Abnormal so GP will mention that - it was 1.08 in Feb and 1.25 last October (same ranges) but no T4 or T3 tested.
Pooky1
in
Thyroid UK
6 days ago
Do not trust your first bone scan
If you are diagnosed with prostate cancer and get a bone scan, this will often reveal a few bone metastases. Then your MO will give you the verdict: lifelong ADT. Usually you will not get radiation or surgery of the prostate because the tumor has already spread. However, there is a study by Dr. Thomas
If you are diagnosed with prostate cancer and get a bone scan, this will often reveal a few bone metastases. Then your MO will give you the verdict: lifelong ADT. Usually you will not get radiation or surgery of the prostate because the tumor has already spread. However, there is a study by Dr. Thomas
GP24
in
Advanced Prostate Cancer
6 days ago
Testosterone Gel
I have been on HRT for several years, I take an oral tablets as the patches didnt suit me and I'm happy with them, but I've been wondering about adding testosterone gel. I've seen a study where Fibro patients used to the gel to good effect for fatigue etc. I know a number of ladies here use it and I
I have been on HRT for several years, I take an oral tablets as the patches didnt suit me and I'm happy with them, but I've been wondering about adding testosterone gel. I've seen a study where Fibro patients used to the gel to good effect for fatigue etc. I know a number of ladies here use it and I
Sparklingsunshine
in
Thyroid UK
6 days ago
Menopause at 29 via zoledax advice on dealing with symptoms please help
Hello. Quick summary tried everything available been on zoledax for 6 months now, specialist has advised to continue and will be having another appointment to get surgery booked in for next year and discuss any new option including trials via nhs. Anyone who has read or gone through menopause knows
Hello. Quick summary tried everything available been on zoledax for 6 months now, specialist has advised to continue and will be having another appointment to get surgery booked in for next year and discuss any new option including trials via nhs. Anyone who has read or gone through menopause knows
Chronic21
in
Endometriosis UK
7 days ago
Nausea when I stop Utrogestan
Hi I'm really struggling, I've been on HRT for about a year and a half. Estrogel and utrogestan. In January I started to experience extreme nausea as soon as I stopped the 2 weeks of 200mg Utrogestan. It became so debilating that my GP referred me to the women's health clinic. The doctor there said as
Hi I'm really struggling, I've been on HRT for about a year and a half. Estrogel and utrogestan. In January I started to experience extreme nausea as soon as I stopped the 2 weeks of 200mg Utrogestan. It became so debilating that my GP referred me to the women's health clinic. The doctor there said as
Peachyhair
in
Menopause and Perimenopause Support
7 days ago
2 spots
I was undetected for a year after pelvic radiation then my PSA went up to .04 so we did a PSMA scan and discovered 2 spots, although one was on a rib. My PSA was .36 so the spots were radiated. I am having a slight pain in the area where the rib is located. My PSA has gone down to .26 so it’s moving
I was undetected for a year after pelvic radiation then my PSA went up to .04 so we did a PSMA scan and discovered 2 spots, although one was on a rib. My PSA was .36 so the spots were radiated. I am having a slight pain in the area where the rib is located. My PSA has gone down to .26 so it’s moving
Howard53545
in
Advanced Prostate Cancer
7 days ago
blood in urine
Prostate removed have been on adt for 3 years & xtandi treatment for 3 months, I exercise a lot. Today I did floor exercises, weights and swam 500 meters fast. When I went to the bathroom to urinate it was all blood. I was told by my oncologist to go to the hospital if the second urination is all
Prostate removed have been on adt for 3 years & xtandi treatment for 3 months, I exercise a lot. Today I did floor exercises, weights and swam 500 meters fast. When I went to the bathroom to urinate it was all blood. I was told by my oncologist to go to the hospital if the second urination is all
Stevegr
in
Advanced Prostate Cancer
8 days ago
Decapeptyl/ hrt
Hi all just wanting to ask a question I have an appointment next week to start Decapeptyl injections My question is should I start the hrt the same day as my injection or is it best to wait a few weeks or even the following month ? Thanks Tina
Hi all just wanting to ask a question I have an appointment next week to start Decapeptyl injections My question is should I start the hrt the same day as my injection or is it best to wait a few weeks or even the following month ? Thanks Tina
Smiley2022
in
Endometriosis UK
9 days ago
Positive case studies
Literature trawl - copy the text and paste into Google search to find papers. This is just the best bits. Jo 9 yearWe present a case of a patient with castration-resistant prostate cancer with proven bone lesions 2 years after the onset of the disease and the current survival of over 9 years. In 2013
Literature trawl - copy the text and paste into Google search to find papers. This is just the best bits. Jo 9 yearWe present a case of a patient with castration-resistant prostate cancer with proven bone lesions 2 years after the onset of the disease and the current survival of over 9 years. In 2013
TomsD1
in
Advanced Prostate Cancer
9 days ago
Newly diagnosed Gleason 9
Hi all, I recently had my prostate taken out and got upgraded to Gleason 9, T3b, seminal vessel and extra prosthetic extension with positive margins but no lymph nodes. I am 56, very fit, and will get my first post operative PSA in September. My pre-op was 9.5. I know a lot of people on this forum
Hi all, I recently had my prostate taken out and got upgraded to Gleason 9, T3b, seminal vessel and extra prosthetic extension with positive margins but no lymph nodes. I am 56, very fit, and will get my first post operative PSA in September. My pre-op was 9.5. I know a lot of people on this forum
OppositePlatypus9910
in
Advanced Prostate Cancer
9 days ago
HRT Patches are they safe?
Hi I have had hot flushes and aching joints, arthritis etc for the last 10 years and hoping these would help. I am 62 had my last period 10 years ago and when I asked back then I was told I couldn't have HRT as it had risks, so I battled through. Now I have VA and I am hoping that when my BP is controlled
Hi I have had hot flushes and aching joints, arthritis etc for the last 10 years and hoping these would help. I am 62 had my last period 10 years ago and when I asked back then I was told I couldn't have HRT as it had risks, so I battled through. Now I have VA and I am hoping that when my BP is controlled
Diamond61
in
Menopause and Perimenopause Support
10 days ago
Consultant, for thyroid, menopause and anything else possible
I'm in Suffolk but can travel to Norfolk, Cambridge, Essex & London My local 'good' endocrinologist does do thyroid but doesn't think my subclinical hypothyroidism needed treating My menopause/hrt is also a bit hit & miss so needs looking at New differential diagnoses could include mast cell activation
I'm in Suffolk but can travel to Norfolk, Cambridge, Essex & London My local 'good' endocrinologist does do thyroid but doesn't think my subclinical hypothyroidism needed treating My menopause/hrt is also a bit hit & miss so needs looking at New differential diagnoses could include mast cell activation
KatyMac68
in
Thyroid UK
10 days ago
Should I take Nubeqa continuously when going to a PSMA Pylarify PET scan or take an intermittent break for a few weeks beforehand?
Should I take Nubeqa continuously when going to a PSMA Pylarify PET scan or break from the Nubeqa for a few weeks beforehand?When getting a PSMA PET scan, I often here advice about temporarily pausing use of whatever drugs that are effectively keeping the PSA scores down at nadir or below .1. The purpose
Should I take Nubeqa continuously when going to a PSMA Pylarify PET scan or break from the Nubeqa for a few weeks beforehand?When getting a PSMA PET scan, I often here advice about temporarily pausing use of whatever drugs that are effectively keeping the PSA scores down at nadir or below .1. The purpose
GeorgeGlass
in
Advanced Prostate Cancer
10 days ago
Anyone using Utrogestan to keep thyroid levels steady?
I’m on T3 only and have been very successful with it for quite a few years. A couple of years back owing to becoming a laydee of a certain age, I was prescribed desogestrel (a progesterone only pill) to keep my hormones levels stable. I had found they were dipping regularly and my dose hadn’t changed
I’m on T3 only and have been very successful with it for quite a few years. A couple of years back owing to becoming a laydee of a certain age, I was prescribed desogestrel (a progesterone only pill) to keep my hormones levels stable. I had found they were dipping regularly and my dose hadn’t changed
Murphysmum
in
Thyroid UK
11 days ago
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