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Benign prostatic hyperplasia
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Intermediate Unfavorable - Started on Orgovyx and then switched to Firmagon have not lowered my PSA now double therapy is this common?
You can look at my profile for my exact diagnosis. However I started on Orgovyx on June 19th and then I was switched to Firmagon and had the loading dose of that on August 28th. Here are my PSA numbers June 19th 7.02 Testosterone 393 July 20th 5.95 Testosterone
You can look at my profile for my exact diagnosis. However I started on Orgovyx on June 19th and then I was switched to Firmagon and had the loading dose of that on August 28th. Here are my PSA numbers June 19th 7.02 Testosterone 393 July 20th 5.95 Testosterone
cnjaz
in
Prostate Cancer Network
7 days ago
casodex to lupron
Please feel free to provide any thoughts, concerns, etc. 1.) prostrate cancer has NOT spread beyond prostrate. 2.) prostrate treatment on hold as we address lung cancer3a. 3.) on 9/24 will stop casodex and get lupron injection to hold back prostrate cancer for 3 months while we treat lung cancer
Please feel free to provide any thoughts, concerns, etc. 1.) prostrate cancer has NOT spread beyond prostrate. 2.) prostrate treatment on hold as we address lung cancer3a. 3.) on 9/24 will stop casodex and get lupron injection to hold back prostrate cancer for 3 months while we treat lung cancer
Cp014
in
Advanced Prostate Cancer
8 days ago
In Search Of "Alternative Natural ADT" Please Help!
I'd like to receive just
ADT
alone for the[i] localized androgen-sensitive PCa[/i] I've been diagnosed with by my urologist, but he's reluctant to do it alone, explaining that it would likely only lead to a [i]castration-resistant condition.[/i] [i] [/i]But I still believe there's some
I'd like to receive just
ADT
alone for the[i] localized androgen-sensitive PCa[/i] I've been diagnosed with by my urologist, but he's reluctant to do it alone, explaining that it would likely only lead to a [i]castration-resistant condition.[/i] [i] [/i]But I still believe there's some
back2health
in
Advanced Prostate Cancer
8 days ago
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Talzenna +xandti+ Elidard rising PSA 8 weeks
I just started back on xandti adt after pet scan 2 months ago. Good for a year and half off adt and zytiga. I found one bone met on the spine and some lymph node low activity. Termed oligometastatic. Zapped with EBRT 4. Weeks ago PSA was .17 now .36. I’m going for another PMA pet scan. from there recommending
I just started back on xandti adt after pet scan 2 months ago. Good for a year and half off adt and zytiga. I found one bone met on the spine and some lymph node low activity. Termed oligometastatic. Zapped with EBRT 4. Weeks ago PSA was .17 now .36. I’m going for another PMA pet scan. from there recommending
Eieio
in
Advanced Prostate Cancer
9 days ago
Is PSMA PET Scan worth it when PSA<0.2
My MO recommends taking PET CT F18 -DCFPYL in case I want to go intermittent after two years of Lupron and Erleada. My PSA is still less than 0.2. I had one PSMA in March 2022 when PSA was rising to 1.03. Scan show 3 preaortic lymph nodes and two spot on ribs. Then 6 weeks RT and ADT (Lupron, Erleada
My MO recommends taking PET CT F18 -DCFPYL in case I want to go intermittent after two years of Lupron and Erleada. My PSA is still less than 0.2. I had one PSMA in March 2022 when PSA was rising to 1.03. Scan show 3 preaortic lymph nodes and two spot on ribs. Then 6 weeks RT and ADT (Lupron, Erleada
Maxi54
in
Advanced Prostate Cancer
3 months ago
More studies showing that SGLT2 inhibitors might be a useful prodrug for PCa
MateoBeach posted on SGLT2 inhibitors a year ago. Now three more studies show promise for prostate cancer. Note that the last study is a preprint. Pharmacological targets of SGLT2 inhibition on prostate cancer mediated by circulating metabolites: A drug-target Mendelian randomization study Y Lin,
MateoBeach posted on SGLT2 inhibitors a year ago. Now three more studies show promise for prostate cancer. Note that the last study is a preprint. Pharmacological targets of SGLT2 inhibition on prostate cancer mediated by circulating metabolites: A drug-target Mendelian randomization study Y Lin,
Graham49
in
Fight Prostate Cancer
10 days ago
Diagnosed today with small cell Mets in liver
I was diagnised 18 months ago with PSA of 125 and 2-3 Mets to bone. None elsewhere. Dana Farber in Boston put me on Relogolix and Darolutemide and brought my PSA down to .02 over 4-5 months , which was described as Super Responder. Had a PSMA PET SCAN, which showed nothing on the prostate and only one
I was diagnised 18 months ago with PSA of 125 and 2-3 Mets to bone. None elsewhere. Dana Farber in Boston put me on Relogolix and Darolutemide and brought my PSA down to .02 over 4-5 months , which was described as Super Responder. Had a PSMA PET SCAN, which showed nothing on the prostate and only one
Cape1
in
Advanced Prostate Cancer
11 days ago
Not impressed with Oncologist
After Prof. Peter Hoskin team consultant visit today Sep 20. 24, Leuprolide injection and bicalutamide were recommended for 6 months before 20 IMRT sessions somewhere in Jan 25, continuing with ADT for up to 2-3 years, but needs monitoring and adjusted accordinglyAfter that, brachy boost was recommended
After Prof. Peter Hoskin team consultant visit today Sep 20. 24, Leuprolide injection and bicalutamide were recommended for 6 months before 20 IMRT sessions somewhere in Jan 25, continuing with ADT for up to 2-3 years, but needs monitoring and adjusted accordinglyAfter that, brachy boost was recommended
Hotoneii
in
Advanced Prostate Cancer
13 days ago
Metastatic Prostate Cancer Resisting to Treatments
My dad (55) is diagnosed with metastatic prostate cancer that spread to his bones (mainly pelvic and ribs). He was put on Lupron, Docetaxel and Nubeqa. He made improvements in the first 4 months. PSA dropped to almost 0. However, once he started radiation and completed that, his conditions were getting
My dad (55) is diagnosed with metastatic prostate cancer that spread to his bones (mainly pelvic and ribs). He was put on Lupron, Docetaxel and Nubeqa. He made improvements in the first 4 months. PSA dropped to almost 0. However, once he started radiation and completed that, his conditions were getting
Aliannado
in
Advanced Prostate Cancer
14 days ago
PSMA pet scan results
Just had my scan on 9/17/24, prior to my scan my PSA was 0.80. I'll be speaking with my MO on 9/23. Any feedback would be helpful. Thanks EXAM DESCRIPTION: 18F-piflufolastat (PYLARIFY) PSMA targeted PET/CT COMPARISON: PET PSMA dated November 7, 2023 INDICATION: History of prostate cancer status
Just had my scan on 9/17/24, prior to my scan my PSA was 0.80. I'll be speaking with my MO on 9/23. Any feedback would be helpful. Thanks EXAM DESCRIPTION: 18F-piflufolastat (PYLARIFY) PSMA targeted PET/CT COMPARISON: PET PSMA dated November 7, 2023 INDICATION: History of prostate cancer status
Rfs1975
in
Advanced Prostate Cancer
14 days ago
Interview request: $120 to you
A project from Malecare's colleagues in the UK : Prostate Cancer Research is determined to provide a better future for people affected by prostate cancer by working towards new breakthrough treatments. As we scale up our work for the patients who need us, we strive to ensure we are keeping the real
A project from Malecare's colleagues in the UK : Prostate Cancer Research is determined to provide a better future for people affected by prostate cancer by working towards new breakthrough treatments. As we scale up our work for the patients who need us, we strive to ensure we are keeping the real
Darryl
Partner
in
Advanced Prostate Cancer
6 months ago
The struggle is over for my husband at 64
My beautiful husband succumbed to complications from prostate cancer this morning at 4:21 AM. If you look at our profile, we tried everything and finally I gave him some testosterone gel during his last week on earth. It’s impossible to tell whether it made a difference, but I do believe that denying
My beautiful husband succumbed to complications from prostate cancer this morning at 4:21 AM. If you look at our profile, we tried everything and finally I gave him some testosterone gel during his last week on earth. It’s impossible to tell whether it made a difference, but I do believe that denying
Chris_Ali
in
Advanced Prostate Cancer
6 months ago
If PSA decreases in MHsPC but ALP increases , is one still castrate sensitive ?
I know that PSA decreasing or remaining steady while on hormone therapy means one is hormone sensitive but if PSA decreases but ALP increases , does that still mean one is hormone sensitive ?
I know that PSA decreasing or remaining steady while on hormone therapy means one is hormone sensitive but if PSA decreases but ALP increases , does that still mean one is hormone sensitive ?
Tinkudi
in
Advanced Prostate Cancer
15 days ago
Ok to do brisk walking before doing psa test ?
Is it ok to do brisk walking just before doing a PSA test. I know One should avoid cycling for a couple of days.
Is it ok to do brisk walking just before doing a PSA test. I know One should avoid cycling for a couple of days.
Tinkudi
in
Advanced Prostate Cancer
15 days ago
Step 2 - mpMRI done, results not good, I'm scared now
Hi all, I've been enjoying following many of your stories and it has helped me prepare for this journey. Thanks to everyone who graciously shares and responds here. My original post and bio tell my story, but I have to add this new information from my mpMRI this morning. Here it is: IMPRESSION:
Hi all, I've been enjoying following many of your stories and it has helped me prepare for this journey. Thanks to everyone who graciously shares and responds here. My original post and bio tell my story, but I have to add this new information from my mpMRI this morning. Here it is: IMPRESSION:
RazorSaw
in
Advanced Prostate Cancer
16 days ago
3 months post ADT ending checkup
Just completed my checkup after ending ADT in May. My doctor was looking to schedule a PSMA scan to build a baseline. Since I was diagnosed Gleason 9 there is a chance that cancer could reoccur without expressing PSA. ---- well my oncologist talked directly with the insurance advisors (I consulted a
Just completed my checkup after ending ADT in May. My doctor was looking to schedule a PSMA scan to build a baseline. Since I was diagnosed Gleason 9 there is a chance that cancer could reoccur without expressing PSA. ---- well my oncologist talked directly with the insurance advisors (I consulted a
chefjlu
in
Advanced Prostate Cancer
16 days ago
ESMO 2024: phase 1/2 trial of oral masofaniten (EPI-7386) plus Enzalutamide compared to Enzalutamide alone in men with mCRPC
This looks promising. The trial enrolled 18 patients who were on androgen deprivation therapy but had not received prior AR pathway inhibitors; some had received chemotherapy in the hormone-sensitive setting. Patients were treated with escalating doses of Masofaniten (EPI-7386), up to 600 mg twice daily
This looks promising. The trial enrolled 18 patients who were on androgen deprivation therapy but had not received prior AR pathway inhibitors; some had received chemotherapy in the hormone-sensitive setting. Patients were treated with escalating doses of Masofaniten (EPI-7386), up to 600 mg twice daily
Maxone73
in
Advanced Prostate Cancer
17 days ago
ESMO 2024: TAMARACK, a randomized phase 2 trial of the B7-H3 targeting ADC Vobramitamab for metastatic CRPC
My sensation is that it is too early to say ho well it works, but SE look pretty harsh! The trial enrolled 181 men with mCRPC who had previously received one androgen receptor pathway inhibitor. Participants were randomized to receive vobramitamab at either 2.0 mg/kg or 2.7 mg/kg every four weeks. The
My sensation is that it is too early to say ho well it works, but SE look pretty harsh! The trial enrolled 181 men with mCRPC who had previously received one androgen receptor pathway inhibitor. Participants were randomized to receive vobramitamab at either 2.0 mg/kg or 2.7 mg/kg every four weeks. The
Maxone73
in
Advanced Prostate Cancer
17 days ago
ESMO 2024: BMS-986365 in heavily pretreated patients with mCRPC
Ok, I am not so impressed with this new molecule, but here it is. BMS-986365 is designed to inhibit androgen receptor (AR) activity through a dual mechanism of degrading the receptor and blocking its function, aiming to overcome resistance to standard AR pathway inhibitors like enzalutamide and abiraterone
Ok, I am not so impressed with this new molecule, but here it is. BMS-986365 is designed to inhibit androgen receptor (AR) activity through a dual mechanism of degrading the receptor and blocking its function, aiming to overcome resistance to standard AR pathway inhibitors like enzalutamide and abiraterone
Maxone73
in
Advanced Prostate Cancer
17 days ago
luPSMA randomised control trial good early results
https://www.youtube.com/watch?v=S_JvSVlOdZ8 https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(24)00440-6/abstract Some phase 2 early results : adding LuPSMA to (ADT + docetaxel) has generated a strong result in men with "newly diagnosed high-volume mHSPC" April 2020 the trial started
https://www.youtube.com/watch?v=S_JvSVlOdZ8 https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(24)00440-6/abstract Some phase 2 early results : adding LuPSMA to (ADT + docetaxel) has generated a strong result in men with "newly diagnosed high-volume mHSPC" April 2020 the trial started
street-air
in
Advanced Prostate Cancer
17 days ago
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