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Randomised clinical trial - prophylactic radiation therapy to asymptomatic bone metastases improved survival
Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial Authors: Erin F. Gillespie, MD, MPH https://orcid.org/0000-0002-1386-1542 gillespe@mskcc.org, Joanna C. Yang, MD, MPH, Noah J. Mathis, BA
Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial Authors: Erin F. Gillespie, MD, MPH https://orcid.org/0000-0002-1386-1542 gillespe@mskcc.org, Joanna C. Yang, MD, MPH, Noah J. Mathis, BA
Graham49
in
Advanced Prostate Cancer
3 months ago
Barry
Hi, Diagnosed with advanced prostate cancer stage 4 gleeson score 4+4, having six monthly degarelix injections, had bad side effects on second injection upset stomach diorea feeling very drained, wondering if 3 monthly injections would be better less chemical in system?
Hi, Diagnosed with advanced prostate cancer stage 4 gleeson score 4+4, having six monthly degarelix injections, had bad side effects on second injection upset stomach diorea feeling very drained, wondering if 3 monthly injections would be better less chemical in system?
littlemount
in
Advanced Prostate Cancer
3 months ago
Prostate cancer treatment and sexual mutilation
Well well. In the midst of the club no one wants to be a part of and just wanted to add my input. It seems that the treatment of prostate cancer often glazes over the fact that you will be sexually impacted severely. Depending on treatment outcome that could be a 0 to 7. Seems like the topic isn’t really
Well well. In the midst of the club no one wants to be a part of and just wanted to add my input. It seems that the treatment of prostate cancer often glazes over the fact that you will be sexually impacted severely. Depending on treatment outcome that could be a 0 to 7. Seems like the topic isn’t really
Yokohama2023
in
Advanced Prostate Cancer
3 months ago
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News about phase 1 trial for mCRPC: BMS-986365
Plenty of hopefully good news at ASCO 2024 on the 25th of Jan "First disclosure of clinical outcomes from Phase 1 trial with BMS-986365 (CC-94676), the company’s first androgen receptor ligand-directed degrader in solid tumors from its targeted protein degradation platform, in metastatic castration-resistant
Plenty of hopefully good news at ASCO 2024 on the 25th of Jan "First disclosure of clinical outcomes from Phase 1 trial with BMS-986365 (CC-94676), the company’s first androgen receptor ligand-directed degrader in solid tumors from its targeted protein degradation platform, in metastatic castration-resistant
Maxone73
in
Advanced Prostate Cancer
4 months ago
Diet and Prostate Cancer
Many of us like myself know much about what is good or not good when it pertains to our diet. That said, I listened to this podcast from Dr. Geo . Figured I would share it. For me it was a good reminder and reinforcing to my diet practices. Hope you all find it helpfull. https://
Many of us like myself know much about what is good or not good when it pertains to our diet. That said, I listened to this podcast from Dr. Geo . Figured I would share it. For me it was a good reminder and reinforcing to my diet practices. Hope you all find it helpfull. https://
85745
in
Advanced Prostate Cancer
4 months ago
Luteolin, ellagic acid and punicic acid and prostate cancer metastasis
Ok here we go again, excuse me if this was already gone over. I know Pomegranate has stated benefits, but in combo with these other supps may increase the benefits according to this study done on patients and our favored friends, the mice- lol. For me if it can't harm and may help then why not.
Ok here we go again, excuse me if this was already gone over. I know Pomegranate has stated benefits, but in combo with these other supps may increase the benefits according to this study done on patients and our favored friends, the mice- lol. For me if it can't harm and may help then why not.
85745
in
Advanced Prostate Cancer
4 months ago
urinary bother duration
after SBRT and now in my final months of lupron, i still have frequency of urination at night. I had spaceOAR inserted before SBRT. Now at eight months, i was hoping the frequency at night 3-4 times would have abated. Have treat oxybutinin. Nothing. Have tried Gemtesa and it practically closed down
after SBRT and now in my final months of lupron, i still have frequency of urination at night. I had spaceOAR inserted before SBRT. Now at eight months, i was hoping the frequency at night 3-4 times would have abated. Have treat oxybutinin. Nothing. Have tried Gemtesa and it practically closed down
Photographerhere
in
Prostate Cancer Network
4 months ago
Thank you everybody - part 2
Part 1 - https://healthunlocked.com/advanced-prostate-cancer/posts/150427052/thank-you-everybody So i drive 30 minutes to get to the clinic, spend 30 minutes, at the clinic, drive 30 minutes to get home. I see the NP (who confers with the MO as needed before and after my visits). 1. They don't
Part 1 - https://healthunlocked.com/advanced-prostate-cancer/posts/150427052/thank-you-everybody So i drive 30 minutes to get to the clinic, spend 30 minutes, at the clinic, drive 30 minutes to get home. I see the NP (who confers with the MO as needed before and after my visits). 1. They don't
skiingfiend
in
Advanced Prostate Cancer
4 months ago
New blood test to detect neuroendocrine PCa
Summary: Researchers have developed a blood test that can reliably detect neuroendocrine prostate cancer and differentiate it from castration-resistant prostate cancer-adenocarcinoma (CRPC-adeno). https://www.sciencedaily.com/releases/2024/01/240110120221.htm
Summary: Researchers have developed a blood test that can reliably detect neuroendocrine prostate cancer and differentiate it from castration-resistant prostate cancer-adenocarcinoma (CRPC-adeno). https://www.sciencedaily.com/releases/2024/01/240110120221.htm
HikerWife
in
Advanced Prostate Cancer
4 months ago
Boosting Prostate Cancer Awareness with One Click: The Power of Your Anonymous Signature on YouTube
Subscribing to a YouTube channel is like signing a petition with an anonymous signature. You're not sent anything, but your subscription has as much power as you signed your name. So-called patient advocates and gurus complain that our community doesn't help to build prostate cancer awareness. The
Subscribing to a YouTube channel is like signing a petition with an anonymous signature. You're not sent anything, but your subscription has as much power as you signed your name. So-called patient advocates and gurus complain that our community doesn't help to build prostate cancer awareness. The
Darryl
Partner
in
Advanced Prostate Cancer
4 months ago
Anti-Androgen Therapy and Bone Tumors in Prostate Cancer
Sorry guys, but I found this and all I can say is it scared the hell out of me. Now I don't know what to think. Maybe someone can sort it out. https://journals.lww.com/oncology-times/fulltext/2021/08050/anti_androgen_therapy_can_fuel_spread_of_bone.16.aspx Jeff Dunn AO, Professor and CEO of the Prostate
Sorry guys, but I found this and all I can say is it scared the hell out of me. Now I don't know what to think. Maybe someone can sort it out. https://journals.lww.com/oncology-times/fulltext/2021/08050/anti_androgen_therapy_can_fuel_spread_of_bone.16.aspx Jeff Dunn AO, Professor and CEO of the Prostate
85745
in
Advanced Prostate Cancer
4 months ago
ASCO 2023: AI-Derived Digital Pathology Biomarker Predicts Benefit of Long-Term ADT with Radiotherapy in Localized High-Risk Prostate Cancer
https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144902-asco-2023-development-and-validation-of-an-ai-derived-digital-pathology-based-biomarker-to-predict-benefit-of-long-term-androgen-deprivation-therapy-with-radiotherapy-in-men-with-localized-high-risk-prostate-cancer-across-multiple-phase-iii-nrg-rtog-trials.html
https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144902-asco-2023-development-and-validation-of-an-ai-derived-digital-pathology-based-biomarker-to-predict-benefit-of-long-term-androgen-deprivation-therapy-with-radiotherapy-in-men-with-localized-high-risk-prostate-cancer-across-multiple-phase-iii-nrg-rtog-trials.html
zeitgeistxx
in
Advanced Prostate Cancer
4 months ago
how to reduce chemo side effects
I will be starting chemo for my prostate cancer in the next few weeks. Any suggestions as to cooling hats, gloves, and/or socks or other ways to reduce the side effects of chemo. What has been your experience with chemo side effects or your endeavors to reduce them? I expect I will be getting a regimen
I will be starting chemo for my prostate cancer in the next few weeks. Any suggestions as to cooling hats, gloves, and/or socks or other ways to reduce the side effects of chemo. What has been your experience with chemo side effects or your endeavors to reduce them? I expect I will be getting a regimen
shipoo
in
Advanced Prostate Cancer
4 months ago
Earlier surrogates of overall survival to speed up new drugs development
there are statisticians (using AI) that are trying to find even earlier predictors to speed up the progress but it seems that progression free survival could already save 2 years for a new drug to be available on the market https://www.pcf.org/news/new-prostate-cancer-foundation-funded-research-to-speed-up-prostate-cancer-clinical-trials-worldwide
there are statisticians (using AI) that are trying to find even earlier predictors to speed up the progress but it seems that progression free survival could already save 2 years for a new drug to be available on the market https://www.pcf.org/news/new-prostate-cancer-foundation-funded-research-to-speed-up-prostate-cancer-clinical-trials-worldwide
Maxone73
in
Advanced Prostate Cancer
4 months ago
blood test to identify neuroendocrine cancer asap
ok I repost this mainly because the University of Trento is one hour from here and I got good friends there (working on CRISPR)…together with Dana-Farber they have developed a blood test to identify if there is an endocrine prostate cancer and the subtype https://medriva.com/cancer/a-breakthrough-in-prostate-cancer-treatment-new-blood-test-identifies-neuroendocrine-subtype
ok I repost this mainly because the University of Trento is one hour from here and I got good friends there (working on CRISPR)…together with Dana-Farber they have developed a blood test to identify if there is an endocrine prostate cancer and the subtype https://medriva.com/cancer/a-breakthrough-in-prostate-cancer-treatment-new-blood-test-identifies-neuroendocrine-subtype
Maxone73
in
Advanced Prostate Cancer
4 months ago
Blood test distinguishes neuroendocrine subtype of advanced prostate cancer
https://www.sciencedaily.com/releases/2024/01/240110120221.htm
https://www.sciencedaily.com/releases/2024/01/240110120221.htm
zeitgeistxx
in
Advanced Prostate Cancer
4 months ago
Lupron Injection denied by Medicare Advantage PPO plan
My husband will need Lupron injections monthly x4. Two before starting radiation, and 2 during radiation treatment. The insurance, Medicare Advantage PPO, denied it. Anyone successfully appealed the denial? Any suggestions from the group? I checked and Medicare part D covers Lupron for the treatment
My husband will need Lupron injections monthly x4. Two before starting radiation, and 2 during radiation treatment. The insurance, Medicare Advantage PPO, denied it. Anyone successfully appealed the denial? Any suggestions from the group? I checked and Medicare part D covers Lupron for the treatment
Inquisitive_one
in
Advanced Prostate Cancer
4 months ago
Holding very low stable usPSA - 0.03X range for six years; no ADT, no chemo.
Eight years ago this month had RP after considerable investigation - nadir 0.050. Eleven months later had salvage RT; done at 0.10. Then after a year of pondering ADT and chemo, when my usPSA was back up to 0.10, I went to Europe for Ferrotran nano-MRI combined with Ga68 PSMA. The nanoMRI lite up
Eight years ago this month had RP after considerable investigation - nadir 0.050. Eleven months later had salvage RT; done at 0.10. Then after a year of pondering ADT and chemo, when my usPSA was back up to 0.10, I went to Europe for Ferrotran nano-MRI combined with Ga68 PSMA. The nanoMRI lite up
NanoMRI
in
Advanced Prostate Cancer
4 months ago
More Evidence Linking ADT for PCa to Adverse Neurocognitive Effects -Meta-analysis shows increased risk of dementia, Parkinson's, depression
[i]As if we needed more reasons to dislike or avoid ADT, here is additional evidence of negative neurocognitive effects. This MedPage Today article will expecially be of special interest to those of us well into our "Golden Years" and on or considering ADT. [/i]
More Evidence Linking ADT for Prostate
[i]As if we needed more reasons to dislike or avoid ADT, here is additional evidence of negative neurocognitive effects. This MedPage Today article will expecially be of special interest to those of us well into our "Golden Years" and on or considering ADT. [/i]
More Evidence Linking ADT for Prostate
cujoe
in
Fight Prostate Cancer
4 months ago
given a choice about duration of ADT
Tall Allen and others. Clean PSMA, , 3+4, 3+4, and 4+3., biopsy. 77yrs old, hit gym daily but have significant side effects of lupron.. Being treated at Comprensive cancer center. Plan was one year of Lupron. After five SBRT, and nine months on adt, my doc is willing to let me terminate my Lupron
Tall Allen and others. Clean PSMA, , 3+4, 3+4, and 4+3., biopsy. 77yrs old, hit gym daily but have significant side effects of lupron.. Being treated at Comprensive cancer center. Plan was one year of Lupron. After five SBRT, and nine months on adt, my doc is willing to let me terminate my Lupron
Photographerhere
in
Prostate Cancer Network
4 months ago
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