Experiences with

Azatadine

Hi. My brother is recently home from hospital after 18 months following a brain injury. He is experiencing a strange sense of reality where everything feels like a dream. It is very distressing for him. Has anyone had similar and worked through this? He is taking amantadine drug. I believe this can cause

Hello all, I haven't been posting much. But I'd appreciate your advice. On Friday, my husband was going about his day, had driven to the grocery pickup, got home, and then started to have small hallucinations (ants that weren't there) and vomited. He texted for me to come home from work, and in the

Anyone taking amantadine? It may be slowing progression. Looking in to means of reducing glutamate excitoxicity which is shown to increase decline, I happened upon the knowledge that Amantadine, is a NMDA receptor antagonist. What I have read so far suggests that Amantadine is indeed Neuroprotective

I have developed dyskinesia and doctors tried reducing levodopa thinking I was getting too much but dyskinesia persisted.

First of all, i would like to write this update after i have been rechecked by the doctors in Switzerland , which was supposed to be in the beginning of January, but due to COVID restrictions, i wasn’t unable to fly. I’m hoping to fly during March, but it’s always unexpected. After a year, i can say

Apart from the AMN, I am generally healthy and not particularly worried about Covid. Maybe because I had my three vaccines and always wear a mask outdoors. I do, however, have one friend who [i]had Long Covid for over a yea[/i]r. And I have posted here before about various of these diseases having

"The answer to the question in the title of this post is “Yes, drug repurposing does work” and in this short blog we shall discuss examples of its utility in Parkinson’s. But first it would be wise to explain the drug development process and why drug repurposing is an exciting area of research that is

I am desperate for suggestions on reducing dyskinesia. I have had gate and balance dominant PD for 11 years now and have always struggled with dyskinesia. Recently I had a fractured femur and am attempting to resume walking with the the help of a walker. However, the dyskinesia is so strong I cannot

Could early treatment with amantadine delay L-dopa-induced dyskinesia onset more than treatment with other symptomatic agents (anticholinergics or MAO-B inhibitors)? New data from a hospital-based retrospective cohort study from Taiwan suggests 'yes' https://onlinelibrary.wiley.com/doi/10.1111/ene.15234

A newly discovered oral molecule, called PD13R, significantly lessened levodopa-induced dyskinesia, its involuntary and jerky movements, while maintaining the therapy’s benefits in a non-human primate model of Parkinson’s disease. Notably, in contrast to Gocovri (amantadine) — an approved therapy to

Hello. Does anyone have experience with Amantadine? I was prescribed it but have concerns.

🙂 This is lengthy, but it does have useful, interesting information. Overview of Adult Onset Cerebellar Ataxia Pravin Khemani, MD The ataxias are clinically heterogenous disorders caused by pathological processes affecting the cerebellum and cerebellar pathways resulting in impaired coordination. The

If i wrote this post 3 days ago, i probably wouldn’t be so positive about it, it was an hard day, with difficult controlling tremor most of the day. But it was a bad day among very good days. Today was a virtually no tremor day. I got used to this roller coaster now, but i had a quite pleasant but also

Is this a symptom of PD, the medication, both or neither?

Amantadine

Hi, I might consider this drug for Dyskinesia, if it gets too severe. My MDS is a little reluctant to prescribe it, because he says it may cause insomnia. Nevertheless, is this drug working for your dyskinesia? How long before it started working for you? My doctor said it could take 4 to 8 weeks.

I decided to keep a journal of my journey - it has been quite a year but I have learned a lot. some of which maybe relevant for new and older PD people. I am not a doctor and this is not a medical opinion but there is lots available to make a stand against PD https://fightparkinsonsdisease.files.wordpress.com

Hi, it is 18 months since my wife's first visit to a neurologist, initially they suspected Parkinson's or Parkinson's plus; PSP was mentioned quite early on and now her diagnosis is suspected PSP. Her main symptoms are eyes closing involuntarily (eyelid opening apraxia) and very quite speech (profound

Hi, your suggestions would help a lot. I am beginning to have dyskinesia more frequently. Mostly worse at night. I take Rytary 3pills 145mg, (8am,12noon,4pm and 8pm). My MDS thinks it is motor fluctuations, caused by uneven plasma level of Levodopa. He suggested that I should add two more pills,

I've needed to write a long post (or a few separate posts) for weeks now, but I'm just too busy. I'm going to try to make time to do some thorough updates on my situation soon, but I have an immediate question: I can't tolerate Sinemet (tried it from Jan. 16-Mar. 10, 2021), so my neuro (MDS) wants me