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Azatadine

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Not living in the real world….really horrible!

Hi. My brother is recently home from hospital after 18 months following a brain injury. He is experiencing a strange sense of reality where everything feels like a dream. It is very distressing for him. Has anyone had similar and worked through this? He is taking amantadine drug. I believe this can cause
Hi. My brother is recently home from hospital after 18 months following a brain injury. He is experiencing a strange sense of reality where everything feels like a dream. It is very distressing for him. Has anyone had similar and worked through this? He is taking amantadine drug. I believe this can cause
Rayoflight123- profile image
Rayoflight123-
in Headway

Sudden loss of ability to move?

Hello all, I haven't been posting much. But I'd appreciate your advice. On Friday, my husband was going about his day, had driven to the grocery pickup, got home, and then started to have small hallucinations (ants that weren't there) and vomited. He texted for me to come home from work, and in the
Hello all, I haven't been posting much. But I'd appreciate your advice. On Friday, my husband was going about his day, had driven to the grocery pickup, got home, and then started to have small hallucinations (ants that weren't there) and vomited. He texted for me to come home from work, and in the
LostinHeadSpace profile image
LostinHeadSpace
in PSP Association

Amantadine : is it Neuroprotective? Can it reduce glutamate excitoxicity?

Anyone taking amantadine? It may be slowing progression. Looking in to means of reducing glutamate excitoxicity which is shown to increase decline, I happened upon the knowledge that Amantadine, is a NMDA receptor antagonist. What I have read so far suggests that Amantadine is indeed Neuroprotective
Anyone taking amantadine? It may be slowing progression. Looking in to means of reducing glutamate excitoxicity which is shown to increase decline, I happened upon the knowledge that Amantadine, is a NMDA receptor antagonist. What I have read so far suggests that Amantadine is indeed Neuroprotective
NeuroResearcher profile image
NeuroResearcher
in Cure Parkinson's
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Any advice about weaning off of levodopa and starting amantadine.

I have developed dyskinesia and doctors tried reducing levodopa thinking I was getting too much but dyskinesia persisted.
I have developed dyskinesia and doctors tried reducing levodopa thinking I was getting too much but dyskinesia persisted.
miller15 profile image
miller15
in Cure Parkinson's

PTT FUS in Switzerland - 1 year update

First of all, i would like to write this update after i have been rechecked by the doctors in Switzerland , which was supposed to be in the beginning of January, but due to COVID restrictions, i wasn’t unable to fly. I’m hoping to fly during March, but it’s always unexpected. After a year, i can say
First of all, i would like to write this update after i have been rechecked by the doctors in Switzerland , which was supposed to be in the beginning of January, but due to COVID restrictions, i wasn’t unable to fly. I’m hoping to fly during March, but it’s always unexpected. After a year, i can say
Markbit profile image
Markbit
in Cure Parkinson's

COVID brain impact similar to Chronic Fatigue Syndrome

Apart from the AMN, I am generally healthy and not particularly worried about Covid. Maybe because I had my three vaccines and always wear a mask outdoors. I do, however, have one friend who [i]had Long Covid for over a yea[/i]r. And I have posted here before about various of these diseases having
Apart from the AMN, I am generally healthy and not particularly worried about Covid. Maybe because I had my three vaccines and always wear a mask outdoors. I do, however, have one friend who [i]had Long Covid for over a yea[/i]r. And I have posted here before about various of these diseases having
monkeybus profile image
monkeybus
in AMN EASIER

DRUG REPURPOSING - DOES IT WORK? by Dr. Simon Stott

"The answer to the question in the title of this post is “Yes, drug repurposing does work” and in this short blog we shall discuss examples of its utility in Parkinson’s. But first it would be wise to explain the drug development process and why drug repurposing is an exciting area of research that is
"The answer to the question in the title of this post is “Yes, drug repurposing does work” and in this short blog we shall discuss examples of its utility in Parkinson’s. But first it would be wise to explain the drug development process and why drug repurposing is an exciting area of research that is
nedim profile image
nedim
in Cure Parkinson's

HOW CAN I REDUCE MY DYSKINESIA?

I am desperate for suggestions on reducing dyskinesia. I have had gate and balance dominant PD for 11 years now and have always struggled with dyskinesia. Recently I had a fractured femur and am attempting to resume walking with the the help of a walker. However, the dyskinesia is so strong I cannot
I am desperate for suggestions on reducing dyskinesia. I have had gate and balance dominant PD for 11 years now and have always struggled with dyskinesia. Recently I had a fractured femur and am attempting to resume walking with the the help of a walker. However, the dyskinesia is so strong I cannot
Joanne_Joyce profile image
Joanne_Joyce
in Cure Parkinson's

Treatment with amantadine delays L-dopa-induced dyskinesia onset more than treatment with other symptomatic agents

Could early treatment with amantadine delay L-dopa-induced dyskinesia onset more than treatment with other symptomatic agents (anticholinergics or MAO-B inhibitors)? New data from a hospital-based retrospective cohort study from Taiwan suggests 'yes' https://onlinelibrary.wiley.com/doi/10.1111/ene.15234
Could early treatment with amantadine delay L-dopa-induced dyskinesia onset more than treatment with other symptomatic agents (anticholinergics or MAO-B inhibitors)? New data from a hospital-based retrospective cohort study from Taiwan suggests 'yes' https://onlinelibrary.wiley.com/doi/10.1111/ene.15234
nedim profile image
nedim
in Cure Parkinson's

Oral Molecule PD13R Safely Eases Dyskinesia Tied to Levodopa in Primate Model

A newly discovered oral molecule, called PD13R, significantly lessened levodopa-induced dyskinesia, its involuntary and jerky movements, while maintaining the therapy’s benefits in a non-human primate model of Parkinson’s disease. Notably, in contrast to Gocovri (amantadine) — an approved therapy to
A newly discovered oral molecule, called PD13R, significantly lessened levodopa-induced dyskinesia, its involuntary and jerky movements, while maintaining the therapy’s benefits in a non-human primate model of Parkinson’s disease. Notably, in contrast to Gocovri (amantadine) — an approved therapy to
nedim profile image
nedim
in Cure Parkinson's

Amantadine?

Hello. Does anyone have experience with Amantadine? I was prescribed it but have concerns.
Hello. Does anyone have experience with Amantadine? I was prescribed it but have concerns.
septimus7 profile image
septimus7
in Cure Parkinson's

Overview of the Ataxias

🙂 This is lengthy, but it does have useful, interesting information. Overview of Adult Onset Cerebellar Ataxia Pravin Khemani, MD The ataxias are clinically heterogenous disorders caused by pathological processes affecting the cerebellum and cerebellar pathways resulting in impaired coordination. The
🙂 This is lengthy, but it does have useful, interesting information. Overview of Adult Onset Cerebellar Ataxia Pravin Khemani, MD The ataxias are clinically heterogenous disorders caused by pathological processes affecting the cerebellum and cerebellar pathways resulting in impaired coordination. The
wobblybee profile image
wobblybee
in Ataxia UK

MRigFUS in Switzerland - 9 months update

If i wrote this post 3 days ago, i probably wouldn’t be so positive about it, it was an hard day, with difficult controlling tremor most of the day. But it was a bad day among very good days. Today was a virtually no tremor day. I got used to this roller coaster now, but i had a quite pleasant but also
If i wrote this post 3 days ago, i probably wouldn’t be so positive about it, it was an hard day, with difficult controlling tremor most of the day. But it was a bad day among very good days. Today was a virtually no tremor day. I got used to this roller coaster now, but i had a quite pleasant but also
Markbit profile image
Markbit
in Cure Parkinson's

I am newly diagnosed and on amantadine 2x daily. I notice I feel much more tired on a daily basis than I used to. I take 1 -2 naps a day.

Is this a symptom of PD, the medication, both or neither?
Is this a symptom of PD, the medication, both or neither?
faybo39495 profile image
faybo39495
in Cure Parkinson's

Has anyone had any experience with Amantadine just been prescribed by my neurologist to help with moderate tremor.

Amantadine
Amantadine
Bramma profile image
Bramma
in Cure Parkinson's

AMANTADINE FOR DYSKINESIA. HAVE YOU AN EXPERIENCE WITH THIS DRUG? PLEASE HELP.

Hi, I might consider this drug for Dyskinesia, if it gets too severe. My MDS is a little reluctant to prescribe it, because he says it may cause insomnia. Nevertheless, is this drug working for your dyskinesia? How long before it started working for you? My doctor said it could take 4 to 8 weeks.
Hi, I might consider this drug for Dyskinesia, if it gets too severe. My MDS is a little reluctant to prescribe it, because he says it may cause insomnia. Nevertheless, is this drug working for your dyskinesia? How long before it started working for you? My doctor said it could take 4 to 8 weeks.
OREOLU profile image
OREOLU
in Cure Parkinson's

What I have learned from 1 year with Early Onset PD - "Glass Half Full"

I decided to keep a journal of my journey - it has been quite a year but I have learned a lot. some of which maybe relevant for new and older PD people. I am not a doctor and this is not a medical opinion but there is lots available to make a stand against PD https://fightparkinsonsdisease.files.wordpress.com
I decided to keep a journal of my journey - it has been quite a year but I have learned a lot. some of which maybe relevant for new and older PD people. I am not a doctor and this is not a medical opinion but there is lots available to make a stand against PD https://fightparkinsonsdisease.files.wordpress.com
blazyb profile image
blazyb
in Cure Parkinson's

Eyes closing after medication

Hi, it is 18 months since my wife's first visit to a neurologist, initially they suspected Parkinson's or Parkinson's plus; PSP was mentioned quite early on and now her diagnosis is suspected PSP. Her main symptoms are eyes closing involuntarily (eyelid opening apraxia) and very quite speech (profound
Hi, it is 18 months since my wife's first visit to a neurologist, initially they suspected Parkinson's or Parkinson's plus; PSP was mentioned quite early on and now her diagnosis is suspected PSP. Her main symptoms are eyes closing involuntarily (eyelid opening apraxia) and very quite speech (profound
Zerachiel profile image
Zerachiel
in PSP Association

ARE YOU A NON TREMOR DOMINANT PD PATIENT WITH DYSKINESIA? IF SO, PLEASE HELP.

Hi, your suggestions would help a lot. I am beginning to have dyskinesia more frequently. Mostly worse at night. I take Rytary 3pills 145mg, (8am,12noon,4pm and 8pm). My MDS thinks it is motor fluctuations, caused by uneven plasma level of Levodopa. He suggested that I should add two more pills,
Hi, your suggestions would help a lot. I am beginning to have dyskinesia more frequently. Mostly worse at night. I take Rytary 3pills 145mg, (8am,12noon,4pm and 8pm). My MDS thinks it is motor fluctuations, caused by uneven plasma level of Levodopa. He suggested that I should add two more pills,
OREOLU profile image
OREOLU
in Cure Parkinson's

Amantadine for tremor?

I've needed to write a long post (or a few separate posts) for weeks now, but I'm just too busy. I'm going to try to make time to do some thorough updates on my situation soon, but I have an immediate question: I can't tolerate Sinemet (tried it from Jan. 16-Mar. 10, 2021), so my neuro (MDS) wants me
I've needed to write a long post (or a few separate posts) for weeks now, but I'm just too busy. I'm going to try to make time to do some thorough updates on my situation soon, but I have an immediate question: I can't tolerate Sinemet (tried it from Jan. 16-Mar. 10, 2021), so my neuro (MDS) wants me
1LittleWillow profile image
1LittleWillow
in Cure Parkinson's
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