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List of good Genetic Tests in Homologous Recombination Deficiency in PCa and the Mechanisms of Resistance to PARP Inhibitors
I was searching RAD50 and PARPinhibitors and since i am going for a high risk genetic consult i came across this good explanation of different genetic testing. Title of article:
Homologous Recombination Deficiency in Ovarian, Breast, Colorectal, Pancreatic, Non-Small Cell Lung and Prostate Cancers
I was searching RAD50 and PARPinhibitors and since i am going for a high risk genetic consult i came across this good explanation of different genetic testing. Title of article:
Homologous Recombination Deficiency in Ovarian, Breast, Colorectal, Pancreatic, Non-Small Cell Lung and Prostate Cancers
KocoPr
in
Advanced Prostate Cancer
1 month ago
Experience/Opinions on: Pembrolizumab + Lenvatinib for NEPC/SCPC
In January I was diagnosed with SCPC with liver metastasis. My first line of treatment was Platinum based chemo (carboplatin+etoposide). This treatment failed after 3 infusions with radiographic progression on CT Scan. ----- ... HEPATOBILIARY: Innumerable bilobar hepatic metastasis have progressed
In January I was diagnosed with SCPC with liver metastasis. My first line of treatment was Platinum based chemo (carboplatin+etoposide). This treatment failed after 3 infusions with radiographic progression on CT Scan. ----- ... HEPATOBILIARY: Innumerable bilobar hepatic metastasis have progressed
skiingfiend
in
Advanced Prostate Cancer
1 month ago
Aspen wins $8M to advance Parkinson’s stem cell therapy
The grant, funded by the California Institute for Regenerative Medicine (CIRM), will support the ongoing Phase 1/2a clinical trial that’s evaluating the treatment in people with Parkinson’s disease. https://parkinsonsnewstoday.com/news/aspen-wins-8-m-advance-stem-cell-therapy-parkinsons-disease/
The grant, funded by the California Institute for Regenerative Medicine (CIRM), will support the ongoing Phase 1/2a clinical trial that’s evaluating the treatment in people with Parkinson’s disease. https://parkinsonsnewstoday.com/news/aspen-wins-8-m-advance-stem-cell-therapy-parkinsons-disease/
Farooqji
in
Cure Parkinson's
1 month ago
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Clinical Trial using Pluvicto without chemo? Anyone know of any I can try?
Failed second line and looking for a clinical trial. I don't want to do chemo. Please let me know! Thx
Failed second line and looking for a clinical trial. I don't want to do chemo. Please let me know! Thx
Youngman-
in
Advanced Prostate Cancer
1 month ago
Please join us Tuesday,May 21st, for our Living Room discussion on Is a Clinical Trial Right for You?
Hello, Please join us in our San Carlos office Tuesday May 21st in person or if you don’t live in the area, you can join us virtually on GO2's YouTube Live channel. We are thrilled to have Jorge J. Nieva, MD, Associate Professor of Clinical Medicine, Keck School of Medicine of USC, Medical Oncologist
Hello, Please join us in our San Carlos office Tuesday May 21st in person or if you don’t live in the area, you can join us virtually on GO2's YouTube Live channel. We are thrilled to have Jorge J. Nieva, MD, Associate Professor of Clinical Medicine, Keck School of Medicine of USC, Medical Oncologist
Michelezeh
Partner
in
Lung Cancer Support
1 month ago
The Immune Mind by Monty Lyman - Radio 4
I'm still working on getting a proper understanding of what this Book of the Week is all about. I keep setting it going, and drifting off to sleep. However, today I was awake enough to listen (with quite a good level of attention) to episode 4, which starts off talking about rheumatoid arthritis and
I'm still working on getting a proper understanding of what this Book of the Week is all about. I keep setting it going, and drifting off to sleep. However, today I was awake enough to listen (with quite a good level of attention) to episode 4, which starts off talking about rheumatoid arthritis and
Hezekiah
in
NRAS
1 month ago
Started Phase 1 trial - RO7656594 yesterday
Started clinical trial through Honor Health Research in Scottsdale yesterday. Day one was intense with multiple labs and EKG's after his first dose. Appointments today and tomorrow without the med but with follow up labs/EKG's. Friday's appointment will be the start of daily medication. Bone scans and
Started clinical trial through Honor Health Research in Scottsdale yesterday. Day one was intense with multiple labs and EKG's after his first dose. Appointments today and tomorrow without the med but with follow up labs/EKG's. Friday's appointment will be the start of daily medication. Bone scans and
Yadifan
in
Advanced Prostate Cancer
2 months ago
Tales from the heart: Fixing flawed ADHD testing
Tales from the heart: Fixing flawed ADHD testing MindTension has developed a direct-to-brain test to precisely diagnose ADHD, removing variables and the fear of imposter syndrome. In Israel, a critical point in the ADHD diagnosis process is the MOXO test: a computerized assessment tool that measures
Tales from the heart: Fixing flawed ADHD testing MindTension has developed a direct-to-brain test to precisely diagnose ADHD, removing variables and the fear of imposter syndrome. In Israel, a critical point in the ADHD diagnosis process is the MOXO test: a computerized assessment tool that measures
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 months ago
#AskChatGPT - Top ADC Treatment for prostate cancer
Several antibody-drug conjugates (ADCs) are emerging as promising treatments for metastatic castration-resistant prostate cancer (mCRPC). Here are some of the latest and most notable ADCs in development: ARX517: This PSMA-directed ADC has shown encouraging preliminary results in the APEX-01 trial.
Several antibody-drug conjugates (ADCs) are emerging as promising treatments for metastatic castration-resistant prostate cancer (mCRPC). Here are some of the latest and most notable ADCs in development: ARX517: This PSMA-directed ADC has shown encouraging preliminary results in the APEX-01 trial.
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
New to Afib- tiredness
Diagnosed a little over a week ago with Afib. On Diltazem and Eloquis. I am 58 years old and always been healthy until now. They have given me Flecainide to start taking daily if I have another episode. My question is about being so tired all the time. I sleep a lot but have to work full time.
Diagnosed a little over a week ago with Afib. On Diltazem and Eloquis. I am 58 years old and always been healthy until now. They have given me Flecainide to start taking daily if I have another episode. My question is about being so tired all the time. I sleep a lot but have to work full time.
Jeep2021
in
AF Association
9 months ago
Korean prostate cancer radiopharmaceutical dosed 1st US patient in P2 trial
FutureChem said Monday that it has recently entered full-scale clinical trials with the first dose of its radiopharmaceutical, FC705, in patients with metastatic castration-resistant prostate cancer (mCRPC) in a U.S. phase 2a study. Source link: https://www.futurechem.co.kr/eng/business/pipeline2
FutureChem said Monday that it has recently entered full-scale clinical trials with the first dose of its radiopharmaceutical, FC705, in patients with metastatic castration-resistant prostate cancer (mCRPC) in a U.S. phase 2a study. Source link: https://www.futurechem.co.kr/eng/business/pipeline2
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
InkMune clinical trial goes on: second cohort is being treated
In phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a biologic therapy In its announcement on Monday, INmune said it successfully completed nine INKmune administrations in the outpatient setting within the first cohort in the trial. None of the patients who have received INKmune so far have
In phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a biologic therapy In its announcement on Monday, INmune said it successfully completed nine INKmune administrations in the outpatient setting within the first cohort in the trial. None of the patients who have received INKmune so far have
Maxone73
in
Advanced Prostate Cancer
2 months ago
💬 Discussion Topic: What Do You Want to Learn About the Pharmaceutical Industry?
Embarking on a journey into the pharmaceutical industry opens up endless possibilities. Whether you're drawn to drug discovery, regulatory processes, or ethical considerations in healthcare, there's a wealth of topics to explore. Join our discussion to share your interests and aspirations for learning
Embarking on a journey into the pharmaceutical industry opens up endless possibilities. Whether you're drawn to drug discovery, regulatory processes, or ethical considerations in healthcare, there's a wealth of topics to explore. Join our discussion to share your interests and aspirations for learning
AnnaHU
HealthUnlocked
in
Research Opportunities
2 months ago
Protection from Coronaviruses That Haven’t Yet Emerged
To paraphrase Ozzy Osbourne, pandemics can spring up without warning. Although 101 years separated the most recent, truly global pandemics - the H1N1 virus killing tens of millions of people from 1918 to 1920 and SARS-COV2 killing an estimated 14.8 million people in 2020-21 alone https://www.ncbi.nlm.nih.gov
To paraphrase Ozzy Osbourne, pandemics can spring up without warning. Although 101 years separated the most recent, truly global pandemics - the H1N1 virus killing tens of millions of people from 1918 to 1920 and SARS-COV2 killing an estimated 14.8 million people in 2020-21 alone https://www.ncbi.nlm.nih.gov
bennevisplace
in
CLL Support
2 months ago
Post op concerns
Had partial Thyroidectomy on 20.03.24 to remove large goitre with nodules. Since the operation I have swelling at the incision site and a dull, throbbing headache daily.Some days a take Paracetamol, some days I don't. Neck still feels very stiff. Saw surgeon on 19.04.24. He advised that this is
Had partial Thyroidectomy on 20.03.24 to remove large goitre with nodules. Since the operation I have swelling at the incision site and a dull, throbbing headache daily.Some days a take Paracetamol, some days I don't. Neck still feels very stiff. Saw surgeon on 19.04.24. He advised that this is
Purplesane
in
Thyroid UK
2 months ago
Anyone participated in AMG50 clinical trial?
has anyone here participated in an AMG 50 clinical trial? if so, what were the adverse events? How bad and for how long? And was the treatment successful in stabilizing or reducing PCa?
has anyone here participated in an AMG 50 clinical trial? if so, what were the adverse events? How bad and for how long? And was the treatment successful in stabilizing or reducing PCa?
Farmhand
in
Advanced Prostate Cancer
2 months ago
Letter I received today
ANNOVIS ANNOUNCES UNBLINDING OF THE BUNTANETAP PHASE III DATA IN PARKINSON’S DISEASE The Phase III study was completed in 4Q 2023 with an original plan for data announcement in 1Q 2024, however the Company faced a delay in the process of data cleaning beyond the original prognosis. Maria Maccecchini
ANNOVIS ANNOUNCES UNBLINDING OF THE BUNTANETAP PHASE III DATA IN PARKINSON’S DISEASE The Phase III study was completed in 4Q 2023 with an original plan for data announcement in 1Q 2024, however the Company faced a delay in the process of data cleaning beyond the original prognosis. Maria Maccecchini
mauigirl18
in
Cure Parkinson's
2 months ago
Ovacome clinical update day 18 May 2024 London
Hello All You are warmly invited to join us for our annual clinical update day on Saturday 18 May from 9:30am to 4:30pm. This event is for anyone affected by ovarian cancer including family and friends and is being held at the Ovacome office in London. The day will be a combination of talks from clinicians
Hello All You are warmly invited to join us for our annual clinical update day on Saturday 18 May from 9:30am to 4:30pm. This event is for anyone affected by ovarian cancer including family and friends and is being held at the Ovacome office in London. The day will be a combination of talks from clinicians
OvacomeSupport
My Ovacome Team
in
My Ovacome
2 months ago
low T4 and T3 normal TSH
I posted earlier in the year about my daughter diagnosed with post partum thyroiditis , no treatment at the time but endocrinologist said he’d keep an eye on her! Her most recent results seem odd to me in that both T4 and T3 are very low but her TSH is also low - her case has been closed and results
I posted earlier in the year about my daughter diagnosed with post partum thyroiditis , no treatment at the time but endocrinologist said he’d keep an eye on her! Her most recent results seem odd to me in that both T4 and T3 are very low but her TSH is also low - her case has been closed and results
Sususulio
in
Thyroid UK
9 months ago
Any guidance appreciated!
Hi everyone, My Dad (77) diagnosed in January w/ stage 4 PC, mets to L5 spine. PET scan showed no other spots elsewhere. PSA was 19 at time of diagnosis, Gleason 10. BRCA negative. PSA is now at 0.2 since starting hormone therapy. Feeling good, no pain. Still works (owns his own company). Started
Hi everyone, My Dad (77) diagnosed in January w/ stage 4 PC, mets to L5 spine. PET scan showed no other spots elsewhere. PSA was 19 at time of diagnosis, Gleason 10. BRCA negative. PSA is now at 0.2 since starting hormone therapy. Feeling good, no pain. Still works (owns his own company). Started
LDC2024
in
Advanced Prostate Cancer
2 months ago
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