In January I was diagnosed with SCPC with liver metastasis.
My first line of treatment was Platinum based chemo (carboplatin+etoposide). This treatment failed after 3 infusions with radiographic progression on CT Scan.
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HEPATOBILIARY: Innumerable bilobar hepatic metastasis have progressed. There are several new lesions and enlargement of the pre-existing lesions. For instance, a 1.5 x 1.1 cm lesion in segment 7 is now 2.7 x 2.5 cm. There is mass effect narrowing the hepatic vessels but the portal and hepatic veins remain patent. No biliary dilation the gallbladder is unremarkable.
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For the 2nd time this year, I was given an estimated 90 days to live without effective 2nd line treatment. Also my MO seems to stand behind this estimate since he has registered me with BC Palliative Care Program (6 mo's to live).
At my urging, my MO reached out to US based Clinics in Seattle, Portland and San Francisco with the goal of seeking out clinical trials relevant to my condition.
Within 1 week I have a spot reserved on the PLANE/PC trial contingent on meeting the eligibility requirements. We are in the processing of working thru that now and I will probably have to travel to Oregon in the near future.
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Does anybody have any experience with or opinions on this trial:
PLANE/PC - Phase 2 - Pembrolizumab + Lenvatinib