Korean prostate cancer radiopharmaceutical dosed 1st US patient in P2 trial

[God_Loves_Me]

FutureChem said Monday that it has recently entered full-scale clinical trials with the first dose of its radiopharmaceutical, FC705, in patients with metastatic castration-resistant prostate cancer (mCRPC) in a U.S. phase 2a study.

Source link:

futurechem.co.kr/eng/busine...

2nd Generation PSMA-targeted Therapeutic Radiopharmaceuticals

Since 177Lu-PSMA-617 injection dose is high, the radiation exposure to normal organs such as salivary glands and kidneys is inevitable. Many patients who have participated in clinical trials actually complained of various side effects from salivary gland radiation exposure. Recently, studies on PSMA-targeted compounds with albumin-binding functional group have been reported. Albumin is the most abundant protein in the blood (40 mg/mL) and the introduction of albumin conjugates into the drug increases the drug's retention time in the blood, resulting in more accumulation of the drug in the target area. This suggests that lower dose than 177Lu-PSMA-617 can significantly reduce damage to normal tissues have while producing the same therapeutic effect. . These 2nd generation PSMA-targeted radiopharmaceuticals are still in basic research stage throughout the world.

Press release :

koreabiomed.com/news/articl...

[Maxone73]

Yes! It's promising!

[spencoid2]

Leave it to the Koreans go Korea (South that is) Typing on a Korean computer which is the best I have had in years. My clothes are the cleanest ever with our LG washer. No complaints about the refrigerator. Next they will cure my cancer Oh and my new dentist is Korean. Do I see a trend here?

[j-o-h-n in reply to spencoid2]

And I own a Kia Sportage. It comes in two sections North and South and split down the middle, into two parts, at the 38th parallel. Note: Don't drive while lunching on Kimchi...

행운을 빕니다, 건강과 좋은 유머.

haeng-un-eul bibnida, geongang-gwa joh-eun yumeo.

Good Luck, Good Health and Good Humor.

j-o-h-n