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not so great Petscan
Friday I had my first Petscan after two cycles of Ibrance and one on Kisqali. I was really hoping for all good results. Unfortunately, it was a mixed bag. My metastasis is my my lungs and there were three spots, two were biopsies and one too small was just assumed to be my breast cancer cells. Well
Friday I had my first Petscan after two cycles of Ibrance and one on Kisqali. I was really hoping for all good results. Unfortunately, it was a mixed bag. My metastasis is my my lungs and there were three spots, two were biopsies and one too small was just assumed to be my breast cancer cells. Well
jltorcz
in
SHARE Metastatic Breast Cancer
4 months ago
How Genomic Biomarkers are Shaping Treatment Decisions
Big Data and AI are powerful... https://www.urotoday.com/video-lectures/prostate-cancer-genomic-classifier/video/mediaitem/3634-deciphering-prostate-cancer-how-genomic-biomarkers-are-shaping-treatment-decisions-paul-nguyen.html
Big Data and AI are powerful... https://www.urotoday.com/video-lectures/prostate-cancer-genomic-classifier/video/mediaitem/3634-deciphering-prostate-cancer-how-genomic-biomarkers-are-shaping-treatment-decisions-paul-nguyen.html
Maxone73
in
Advanced Prostate Cancer
8 months ago
Dual Action Hormone Therapy Targeting Two Parts of Androgen Receptor for mCRPC
Phase I/II trial of masofaniten combined with enzalutamide, a novel hormonal therapy for mCRPC. Masofaniten, a first-in-class N-terminal ligand antagonist for the androgen receptor, shows promise in overcoming resistance to current hormonal therapies. Hopefully a new weapon for us!
Phase I/II trial of masofaniten combined with enzalutamide, a novel hormonal therapy for mCRPC. Masofaniten, a first-in-class N-terminal ligand antagonist for the androgen receptor, shows promise in overcoming resistance to current hormonal therapies. Hopefully a new weapon for us!
Maxone73
in
Advanced Prostate Cancer
8 months ago
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Anyone tried cabazitaxel (Jevtana) monotherapy?
If you've tried cabazitaxel [u]
without
[/u] ADT, I would appreciate hearing about your side effects and effectiveness. I'm currently in excellent shape at age 72. Previously I tolerated docetaxel (which along with radiation of abdominal lymph nodes helped me return to undetectable PSA for 4+ years
If you've tried cabazitaxel [u]
without
[/u] ADT, I would appreciate hearing about your side effects and effectiveness. I'm currently in excellent shape at age 72. Previously I tolerated docetaxel (which along with radiation of abdominal lymph nodes helped me return to undetectable PSA for 4+ years
ron_bucher
in
Advanced Prostate Cancer
8 months ago
Pleur x catheter
Update:- good news: l don't need pericardial effusion window surgery. - l did get a pleur x catheter placed last Friday. The procedure went well. I've had 2 drainage at home so far. - l would appreciate showering advice. I wrapped the dressing in place and seal plastic wrap but water still seeped into
Update:- good news: l don't need pericardial effusion window surgery. - l did get a pleur x catheter placed last Friday. The procedure went well. I've had 2 drainage at home so far. - l would appreciate showering advice. I wrapped the dressing in place and seal plastic wrap but water still seeped into
NPmary
in
SHARE Metastatic Breast Cancer
4 months ago
lymphedema from prostate cancer, any advice on how to manage?
One of my dad’s biggest issues with prostate cancer is severe lymphedema from the waist down. He used to just have it in his right leg from lymph node removal during RP. Since being on the lynparza in January both sides have swelled up as well as scrotum and everything else below the waist. He was told
One of my dad’s biggest issues with prostate cancer is severe lymphedema from the waist down. He used to just have it in his right leg from lymph node removal during RP. Since being on the lynparza in January both sides have swelled up as well as scrotum and everything else below the waist. He was told
LJGD
in
Advanced Prostate Cancer
4 months ago
Pinostilbene inhibits the Enz-resistant CRPC cell line by inhibiting AR variant 7
i take pterostilbene daily which pinostilbene is a metabolite of pterostilbene. in any event if you are failing on enzalutamide or any PCa warrior you probably should take pterostilbene. Below is a 2023 in-depth article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550987/ Pinostilbene inhibits
i take pterostilbene daily which pinostilbene is a metabolite of pterostilbene. in any event if you are failing on enzalutamide or any PCa warrior you probably should take pterostilbene. Below is a 2023 in-depth article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550987/ Pinostilbene inhibits
KocoPr
in
Fight Prostate Cancer
8 months ago
PSA +
Is a PSA increase from .13 to .20 a concern? I'm on Eligard and Zytiga & Prednisone + Xgeva.
Is a PSA increase from .13 to .20 a concern? I'm on Eligard and Zytiga & Prednisone + Xgeva.
TommyCarz2
in
Advanced Prostate Cancer
8 months ago
Advancements on drugs delivery: interesting review (and with drugs I meant medicine!)
A review on advancements in the application of starch-based nanomaterials in biomedicine: Precision drug delivery and cancer therapy, just one of the many delivery strategies that are being developed sometimes I forget that we have plenty of chemotherapeutics, also new ones that can diversify our strategy
A review on advancements in the application of starch-based nanomaterials in biomedicine: Precision drug delivery and cancer therapy, just one of the many delivery strategies that are being developed sometimes I forget that we have plenty of chemotherapeutics, also new ones that can diversify our strategy
Maxone73
in
Advanced Prostate Cancer
4 months ago
Back MRI Showed Pelvic Mass
Hello all! I am new here, so this is my first post. I had a back MRI in September 2023 in preparation for possible back surgery. The results of the MRI showed a pelvic mass in the area of left ovary. I took this information to my Gyn, who referred me to a GynOnc because of my age (65), the results
Hello all! I am new here, so this is my first post. I had a back MRI in September 2023 in preparation for possible back surgery. The results of the MRI showed a pelvic mass in the area of left ovary. I took this information to my Gyn, who referred me to a GynOnc because of my age (65), the results
retiredteacher1
in
My Ovacome
8 months ago
Studies help explain why some prostate cancers become resistant to hormone therapy
https://www.sciencedaily.com/releases/2023/12/231204135037.htm
https://www.sciencedaily.com/releases/2023/12/231204135037.htm
zeitgeistxx
in
Advanced Prostate Cancer
8 months ago
Pluvicto and low Hemoglobin
Hi all, My dad received his second infusion of pluvicto on February 14. About a week ago his hemoglobin dropped to 65. After a unit of blood it went up to around 85 and then every 3 days or so it drops back down the high 60’s. My dad does have prostrate cancer in his bones and lymph nodes. My question
Hi all, My dad received his second infusion of pluvicto on February 14. About a week ago his hemoglobin dropped to 65. After a unit of blood it went up to around 85 and then every 3 days or so it drops back down the high 60’s. My dad does have prostrate cancer in his bones and lymph nodes. My question
Uman101
in
Advanced Prostate Cancer
4 months ago
Avodart and Flomax
Hello brothers. Is it safe to use Avodart and Flomax with advanced prostate cáncer? I am tired of getting up to pee 7 or 8 times a night.
Hello brothers. Is it safe to use Avodart and Flomax with advanced prostate cáncer? I am tired of getting up to pee 7 or 8 times a night.
CountryJoe
in
Advanced Prostate Cancer
8 months ago
exciting clinical trial
My very long time (20 years!) MBC changed from E+ to triple negative a few months ago and yesterday I was looking on line for clinical trials for TNBC and found one that looks exciting to me, whether I qualify for it or not. It's sponsored by Lyell Immunopharma and targets CAR T cells. I have no idea
My very long time (20 years!) MBC changed from E+ to triple negative a few months ago and yesterday I was looking on line for clinical trials for TNBC and found one that looks exciting to me, whether I qualify for it or not. It's sponsored by Lyell Immunopharma and targets CAR T cells. I have no idea
PJBinMI
in
SHARE Metastatic Breast Cancer
4 months ago
Heading down hospice road too…
I’m so sorry to hear about your dad 😢 I’m in a very similar situation with my dad, age 71, Gleason 9 with Mets to bone, lungs, lymph nodes and now a tumor in his bladder. Zytiga worked for him for years, but last January started with more bone Mets and lymph nodes, zytiga restarted and failed. Tried
I’m so sorry to hear about your dad 😢 I’m in a very similar situation with my dad, age 71, Gleason 9 with Mets to bone, lungs, lymph nodes and now a tumor in his bladder. Zytiga worked for him for years, but last January started with more bone Mets and lymph nodes, zytiga restarted and failed. Tried
LJGD
in
Advanced Prostate Cancer
4 months ago
surgical pathology - IDC
Can anyone review pathology? Shows IDC but negative everything else. Doctor is not recommending radiation. Thoughts? Life expectancy? Chance of reoccurrence? TUMOR Histologic Type: Acinar adenocarcinoma, conventional (usual) Histologic Grade: Grade: Grade group 2 (Gleason Score 3 + 4 = 7) Percentage
Can anyone review pathology? Shows IDC but negative everything else. Doctor is not recommending radiation. Thoughts? Life expectancy? Chance of reoccurrence? TUMOR Histologic Type: Acinar adenocarcinoma, conventional (usual) Histologic Grade: Grade: Grade group 2 (Gleason Score 3 + 4 = 7) Percentage
Granolaberry
in
Prostate Cancer Network
4 months ago
Lupus and Radiotherapy
Hi everyone ; I have SLE and APS and take Warfarin ; this has been my situation for around 25 years. I was diagnosed with Prostate cancer around sixteen months ago and have been on Hormone therapy for fourteen months. I was offered Radiotherapy around nine months ago , but due to the possible side
Hi everyone ; I have SLE and APS and take Warfarin ; this has been my situation for around 25 years. I was diagnosed with Prostate cancer around sixteen months ago and have been on Hormone therapy for fourteen months. I was offered Radiotherapy around nine months ago , but due to the possible side
jamesroybuck
in
LUPUS UK
4 months ago
Advice on hormonal treatment?
hi all, 10 days post-lap here. Unfortunately ended up losing my left ovary and tube - had 4 endometriomas on it, 1 of which was 8cm, and this was all adhered to my rectum. So the surgeon said it needed to come out. I’m waiting for a post-op appointment but the consultant said the endo will likely come
hi all, 10 days post-lap here. Unfortunately ended up losing my left ovary and tube - had 4 endometriomas on it, 1 of which was 8cm, and this was all adhered to my rectum. So the surgeon said it needed to come out. I’m waiting for a post-op appointment but the consultant said the endo will likely come
Apprentice_Hag
in
Endometriosis UK
4 months ago
What do you think?
I’ve been on Lupron and Xgeva since 2014 and have had many other treatments along the way. As my PSA rose I found my best treatment was Xtandi. I had pretty good results from 2017 to 2020 , then my PSA moved upward again. Looks like I’m going to fail with Nubeqa, which I have been on for 2 1/2 months
I’ve been on Lupron and Xgeva since 2014 and have had many other treatments along the way. As my PSA rose I found my best treatment was Xtandi. I had pretty good results from 2017 to 2020 , then my PSA moved upward again. Looks like I’m going to fail with Nubeqa, which I have been on for 2 1/2 months
docbulldog
in
Advanced Prostate Cancer
8 months ago
What remains?
My husband's PSA count is 3631. He's had every treatment bar Lutetium and immunotherapy and he doesn't have the BRCA gene. Are we at EOL? He, although emaciated, believes that it's not over yet.
My husband's PSA count is 3631. He's had every treatment bar Lutetium and immunotherapy and he doesn't have the BRCA gene. Are we at EOL? He, although emaciated, believes that it's not over yet.
Eala
in
Advanced Prostate Cancer
4 months ago
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