What do you think?

[docbulldog]

I’ve been on Lupron and Xgeva since 2014 and have had many other treatments along the way. As my PSA rose I found my best treatment was Xtandi. I had pretty good results from 2017 to 2020 , then my PSA moved upward again. Looks like I’m going to fail with Nubeqa, which I have been on for 2 1/2 months, my PSA jumped from 176 to 194 and then up to 224.

Tomorrow I will see my oncologist and ask if I can go back on Xtandi and combine that with chemo or some other second line treatment.

[Tall_Allen]

I suggest you email him this link before your meeting so he has a chance to review it:

thelancet.com/journals/lano...

[j-o-h-n]

Hey Doc,

2 1/2 months and you're giving up Nubeqa...... don't you two doctors want to give it a chance.....So far my usage has been a hit. (See my old post*)....

*Never mind you did see my old post.

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 12/06/2023 4:30 PM EST

[docbulldog in reply to j-o-h-n]

Dr wants me to continue Nubeqa and possibly add chemo again after upcoming Ct/Bone scan.

[j-o-h-n in reply to docbulldog]

I can't speak to the chemo..........and I'm not a Doc like you who can give advice....... but always remember God is on your side..... Wishing you -

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 12/06/2023 5:54 PM EST

[DrFeeelgood]

mine has been ticking up too. Spoke with Dr. Sartor and since my last PSmA pet showed uptake, he wants me to try Pluvicto.

[Ian996]

I started Xtandi in June of 2022 My PSA was 0.69 and climbing

By December it had dropped to 2.27 but then gradually started to rise.

By June of 2023 the PSA was up to 0.79. I had a ga 68 PSMA pet scan that showed some PSA uptake in my upper right lung This was treated with SBRT Another PSMA PET scan in Aug 2023 showed I was clear But My PSA was up to 2.6. However it fell to 2.2 by sept 2023 and has since risen back up to 2.4 in Nov 2023. Another PSMA PET scan on Nov 30 2023 shows more mets on my spine Time for chemo I think The Xtandi doesnt appear to be working on me