Experiences with

Alogliptin / Metformin

Hi Folks Looking for a little help here. I am 18 months post MI non stemmi 2 stents a ruptured stump ! 3 blockages. 95% & 85% LAd & Circ. Third blockage not stented. Felt 100% before the heart attack, since I am crippled with pain. I have been back in and had another angiogram and there is narrowing

New international study, below [1]. "Secondary analysis of COU-AA-301 and COU-AA-302" [2] & [3]. Objective: To determine whether metformin or statins ± abiraterone acetate plus prednisone/prednisolone (AAP) influence OS {overall survival} and PSA-RR {prostate specific antigen response rate}.

I'm curious about the opinions of members here on how they would currently rank Neutraceutical and off-label use drugs in order of highest benefit potential (most confirming clinical trial evidence combined with actual therapeutic or synergistic therapeutic effect) in slowing/stopping PCa progression

I've been studying Metformin (not Berberine, yet). My conclusion reading all the latest studies, especially the large meta-studies, is that evidence is weak on Metformin having a significant positive effect BY ITSELF. There appears to be significant evidence it has a positive effect when used synergistically

Hello - the last few days have been not so good - no energy or motivation and this morning I had my breakfast and felt so sick afterwards I had to go back to bed. It has been slowly going downhill for a few days now.My biggest worry is that this all points to kidney function and the dialysis question

Having been told 3 years ago that I was pre diabetic I made as many changes to my diet and lifestyle (other health conditions and covid permitting) to try and avoid progressing to the "I am diabetic" status but today I have been told I am diabetic, steroid induced. My doctor prescribed gliclazide in

New study below [1]. Anyone here using Salmon Protein Hydrolysate? FWIW: "A growing body of evidence implicates iron dysmetabolism in prostate cancer progression. A bioactive peptide-rich salmon protein hydrolysate (SPH) has previously been demonstrated to modulate iron homeostatic mechanisms.

Hello All, my first post and I'm afraid it will be a long one but perhaps someone has had similar experiences and can help. I am male and 53 years old. I’ve had a diagnosis of Raynaud’s since my teens. Over the last ten years or so I developed visible red veins on the backs of my hands, forearms, feet

Prostate cancer (PCa) is a common type of cancer affecting male population. PCa treatments have side effects and are temporarily effective, so new therapeutic options are being investigated. Due to the high demand of energy for cell proliferation, an increase in the expression and activity of lipogenic

I know that some of you take metformin. I read that it comes from a natural ingredient called French lilac, also known as Goat's Rue. It is in other plants as well. Has anyone taken any of those natural forms instead of metformin? Thanks.

so so fed up and in tears. The self injecting of B12 is going well, not arranged re checking of bloods yet going to ask in a few months. So I am fat, have carried extra fat for a few years, but seems to have got out of hand last couple. Early last year had all sorts of blood done after insisting

This is my season for more radiation treatments. This coming week I will have 5 SBRT treatments in 5 days to two newly identified small lymph nodes found on my latest PSMA scan. One in the right pelvis (external iliac) and the other in the abdomen near the celiac plexus. The latter now makes my "officially

Thank you! Your responses to my query regarding specific tests that assist in determining pernicious anemia will be incredibly helpful. I looked on MyChart - my medical clinic's website that provides patients direct access to their test results. Here is what I found along with responses to some of

I am not a diabetic. Before having my thyroidectomy my glucose levels never rose above 82. Controlling by morning blood sugars have been especially difficult, maybe due to taking the meds at 6am while the "Dawn Effect" is still present. Do anyone exercise in the mornings before taking their meds

Men's use of Metformin just before conception is linked to a 40% increase in birth defects, study finds Interesting. Metformin has anti testosterone effect. CNN: Men's use of diabetes drug just before conception is linked to a 40% increase in birth defects, study finds. https://www.cnn.com/2022

But: "Who uses it today? Almost nobody." "We have answered the questions and closed the book." As reported in 2003, the risk for prostate cancer over the initial 7-year study period was 25% lower with finasteride than with placebo. That risk reduction now "goes out to 16 years, at least," (unlike ADT

Hi everyone, I’m a T1D and was diagnosed at age 26yrs. I was originally misdiagnosed as T2D by my GP and started on metformin. Although it worked for a while, I became progressively sicker and was later referred into the hospital for support. Like many people, I manage my diabetes with a combination

Hi everyone, I still am continuing my Levo trial with 50mcg. I have read plenty in older posts about interference and wanted some help to figure out which stuff can go together and which needs spacing out.. I take these: - Levo 50mcg - Vitamin D 4,000 IU drops - Folic Acid 5mg - Myo Inositol - Berberine

I think this is the wrong place to post, but not sure where to as it's both related to PCOS, T1D, Insulin resistance and Infertility, some of which are related/conditioned by Hashi.. So, basically was researching recently and discovered that Berberine may have very positive effects (in some studies

What do you think about: “Metformin Use Linked to Increased Dementia, Parkinson's Risk in Patients With Diabetes” https://www.medscape.com/viewarticle/877965. With NMN, niacin or NR I feel a slight tingling sensation inside my head which I take as my brain being energized, but metformin causes me to