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Androgen deprivation therapy (ADT)
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Can Nubeqa (Darolutamide) be used instead of normal ADT drugs for localized PCa?
It seems that this drug has fewer side effects than the usual
ADT
drugs and from what I can gather does a pretty good job of preventing the growth and spread of PCa. So my question is; Can we use this drug in place of
ADT
when we also use RT to get on top of localised PCa?
It seems that this drug has fewer side effects than the usual
ADT
drugs and from what I can gather does a pretty good job of preventing the growth and spread of PCa. So my question is; Can we use this drug in place of
ADT
when we also use RT to get on top of localised PCa?
Mike58
in
Advanced Prostate Cancer
8 months ago
PSA holding low after all!!
With a warm-hearted attitude, somehow enthusiastic but foolish too, as these things are never static, at least I will have some quiet and smooth times ahead for a few months again :-) I have a doctor appointment in a week from now and it is 2 years I started
ADT
. Wish you all good health, Paulo
With a warm-hearted attitude, somehow enthusiastic but foolish too, as these things are never static, at least I will have some quiet and smooth times ahead for a few months again :-) I have a doctor appointment in a week from now and it is 2 years I started
ADT
. Wish you all good health, Paulo
Paulo1968
in
Advanced Prostate Cancer
6 months ago
Treatment awaited
My recurrent state is limited to a relatively low PSA and three avid lymph nodes with no prostate or pelvic avidity after original whole of pelvis radiation and four year
ADT
holiday So far as I can see the clinical trials for oligometastatic recurrence concern <5 bone metastases +/-LNs.
My recurrent state is limited to a relatively low PSA and three avid lymph nodes with no prostate or pelvic avidity after original whole of pelvis radiation and four year
ADT
holiday So far as I can see the clinical trials for oligometastatic recurrence concern <5 bone metastases +/-LNs.
Sisyphus
in
Advanced Prostate Cancer
9 days ago
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Old Guy Update
I had EBRT and 24 months of
ADT
which was terminated in October of 2022. My PSA at that time was undetectable and my Testosterone was also undetectable. It’s now July 2024, and my PSA is 0.2 and my Testosterone is 10.
I had EBRT and 24 months of
ADT
which was terminated in October of 2022. My PSA at that time was undetectable and my Testosterone was also undetectable. It’s now July 2024, and my PSA is 0.2 and my Testosterone is 10.
TottenhamMan
in
Advanced Prostate Cancer
18 days ago
How important is missing 2 months of ADT?
How important is missing 2 months of
ADT
for the effectiveness of the RT? I don't wish to be antagonistic, but I'm pretty pissed because of their mistake. I just don't know how important it is. Any data out there about gaps in
ADT
?
How important is missing 2 months of
ADT
for the effectiveness of the RT? I don't wish to be antagonistic, but I'm pretty pissed because of their mistake. I just don't know how important it is. Any data out there about gaps in
ADT
?
Eadgbe
in
Prostate Cancer Network
9 months ago
ISO a third MO opinion for my dad
Put on
adt
and zytiga (not sure of spelling), scans show pelvic bed spots and 1 on s1, radiation summer of 22 and have been undetectable since. Now both advent health RO &MO and moffitt MO want him to stop the meds. He wants to but is very uneasy about it, as we all are.
Put on
adt
and zytiga (not sure of spelling), scans show pelvic bed spots and 1 on s1, radiation summer of 22 and have been undetectable since. Now both advent health RO &MO and moffitt MO want him to stop the meds. He wants to but is very uneasy about it, as we all are.
Dsmejkal88
in
Advanced Prostate Cancer
5 months ago
PSA uptick
Initially treated with docetaxel +
ADT
. His PSA has been at/near undetected (<0.01-0.02) for several years, but recently there has been an uptick to 0.08 (similar on a recheck, so not lab error). Obviously still low-level, but concerning signal.
Initially treated with docetaxel +
ADT
. His PSA has been at/near undetected (<0.01-0.02) for several years, but recently there has been an uptick to 0.08 (similar on a recheck, so not lab error). Obviously still low-level, but concerning signal.
mediocra
in
Advanced Prostate Cancer
5 months ago
Estrogen for Bone Health in PCa patient.
Treatment was conventional
ADT
using Firmagon for 4 months before RT using IMRT @78Gy over 39 sessions in Dec 2019. By Sep 2021 PSA started rising. Was advised Nubeqa as there was no spread visible on PSMA Pet CT scan. Preceding Nubeqa I had an orchidectomy.
Treatment was conventional
ADT
using Firmagon for 4 months before RT using IMRT @78Gy over 39 sessions in Dec 2019. By Sep 2021 PSA started rising. Was advised Nubeqa as there was no spread visible on PSMA Pet CT scan. Preceding Nubeqa I had an orchidectomy.
binati
in
Advanced Prostate Cancer
1 month ago
Recovery of Testosterone
We all have heard about how long it takes to recover testosterone after you stop
ADT
. You probably also heard how age affects recovery time. The older you are the longer it takes and the T may never recover. The type of
ADT
you take can also affect recovery time - shot versus pill.
We all have heard about how long it takes to recover testosterone after you stop
ADT
. You probably also heard how age affects recovery time. The older you are the longer it takes and the T may never recover. The type of
ADT
you take can also affect recovery time - shot versus pill.
Mgtd
in
Prostate Cancer Network
6 months ago
Brachyboost and PSA progression free survival question
”We can proceed with EBRT followed by LDR brachytherapy boost and minimum 6 months of
ADT
(as per Japanese randomized trial (IJRPBP 2023), where 6 months vs 24 months of hormones together with EBRT prostate brachytherapy boost in high risk patients yield completely the same results).
”We can proceed with EBRT followed by LDR brachytherapy boost and minimum 6 months of
ADT
(as per Japanese randomized trial (IJRPBP 2023), where 6 months vs 24 months of hormones together with EBRT prostate brachytherapy boost in high risk patients yield completely the same results).
EvFC
in
Advanced Prostate Cancer
3 months ago
Targeting Mets w SBRT- what’s your experience?
Have any of you guys had any luck targeting distant metastases with SBRT after your mets remained small or dormant while on
ADT
but after PSMA scans had showed more in number than olago (more than five mets)?
Have any of you guys had any luck targeting distant metastases with SBRT after your mets remained small or dormant while on
ADT
but after PSMA scans had showed more in number than olago (more than five mets)?
SeattleDan
in
Advanced Prostate Cancer
5 months ago
Side effect of Lupron
My husband was just diagnosed with PC back in April, and he is on
ADT
while waiting for his CK treatment this month. After three-weeks of Lupron injection, he now has a swollen right foot and ankle in the last three days and his BP sometimes runs high.
My husband was just diagnosed with PC back in April, and he is on
ADT
while waiting for his CK treatment this month. After three-weeks of Lupron injection, he now has a swollen right foot and ankle in the last three days and his BP sometimes runs high.
kiyo
in
Prostate Cancer Network
2 months ago
High PSA upon diagnosis, treatment , and outcome
As a result had aggressive tri modality treatment .. brachytherapy seeds, 15 linac radiation sessions, and 9 months o
ADT
..just stopped .. The thing is I’m in Japan and didn’t have access to a PSMA pet scan.. plan to get one down the road now…Anyone else in the same boat?
As a result had aggressive tri modality treatment .. brachytherapy seeds, 15 linac radiation sessions, and 9 months o
ADT
..just stopped .. The thing is I’m in Japan and didn’t have access to a PSMA pet scan.. plan to get one down the road now…Anyone else in the same boat?
Yokohama2023
in
Prostate Cancer Network
4 months ago
Zytiga , prednesone , Options ?
The question is according to a study , per Tall Allen , Stampede Study , I could drop the Zytiga , prednisone but stay with
ADT
, Eligard for 1 more year . Im not shure what I want to do . All Labs are good .
The question is according to a study , per Tall Allen , Stampede Study , I could drop the Zytiga , prednisone but stay with
ADT
, Eligard for 1 more year . Im not shure what I want to do . All Labs are good .
reconjj
in
Advanced Prostate Cancer
5 months ago
Results from 4 Genomic labs
GHANDI suggests
ADT
+ Docetaxel We are also looking into the clinical trial OR-503 m AB (Cemiplimab/Libtayo) There are so many variables for eligibility in Clinical Trials. He is excluded from many bc of no chemo as of yet. Plus, many require bone metastasis. Thank you for any thoughts!
GHANDI suggests
ADT
+ Docetaxel We are also looking into the clinical trial OR-503 m AB (Cemiplimab/Libtayo) There are so many variables for eligibility in Clinical Trials. He is excluded from many bc of no chemo as of yet. Plus, many require bone metastasis. Thank you for any thoughts!
JolleySprings
in
Advanced Prostate Cancer
2 months ago
Treatment and Prevention Strategies for Cognitive Function in PCa
Paul/MB 1) Estradiol Patches during
ADT
and ARSI therapies. Also effectively supports
ADT
by helping suppress the hypothalamic-piruitary-testicular axis (LHRH inhibition).
Paul/MB 1) Estradiol Patches during
ADT
and ARSI therapies. Also effectively supports
ADT
by helping suppress the hypothalamic-piruitary-testicular axis (LHRH inhibition).
MateoBeach
in
Fight Prostate Cancer
7 months ago
Declining psa #8
Gm folks, hope all is well during this Christmas season… I’ve just received my 8th psa test after getting off
ADT
, 9 months of using alternative meds ivermectin, cbd oil turmeric zinc ashwaganda n dim a natural estrogen blocker solely.
Gm folks, hope all is well during this Christmas season… I’ve just received my 8th psa test after getting off
ADT
, 9 months of using alternative meds ivermectin, cbd oil turmeric zinc ashwaganda n dim a natural estrogen blocker solely.
Nfler
in
Advanced Prostate Cancer
7 months ago
What they don't tell you about Androgen Deprivation Therapy (ADT, hormone therapy) unedited version
ADT
Educational Program Info: https://www.lifeonadt.com/
ADT
Educational Program Info: https://www.lifeonadt.com/
Darryl
Partner
in
Advanced Prostate Cancer
9 months ago
PSA rising on Triplet Therapy after <18m
His quality of life has been good while on
ADT
. I am trying to get a better sense of what QoL will be going forward, assuming he will require different treatments, either in addition to or alongside
ADT
. Besides the cancer, his health is very good.
His quality of life has been good while on
ADT
. I am trying to get a better sense of what QoL will be going forward, assuming he will require different treatments, either in addition to or alongside
ADT
. Besides the cancer, his health is very good.
nyc_son
in
Advanced Prostate Cancer
5 months ago
Where do I go for alternative to continuous ADT?
I want to an alternative to continuous
ADT
, whether its IADT, BAT or something else, in hopes of preventing castration resistance. I live on the East Coast of U.S. I exercise a lot each day and have cleaned up my diet.
I want to an alternative to continuous
ADT
, whether its IADT, BAT or something else, in hopes of preventing castration resistance. I live on the East Coast of U.S. I exercise a lot each day and have cleaned up my diet.
Forest1160
in
Fight Prostate Cancer
8 months ago
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