Trodelvy and low white blood cell count

[Tanyateresa]

Hi lovely ladies I'm into my third month of Trodelvy infusions. All seems to be going well except for my low white blood cell count which a couple of times has been too low to admit the treatment. Just wondered if anyone else had this problem and what remedies have you found - nutrition or suplements?

Thanks again and a big hug from Spain

[Pimpelmees]

Hello Tanyateresa. I had problems with my white blood cell counts when I was on Ribociclib. My neutrophils dropped dramatically the first cycle from 5.0 to 1.2. I investigated and found a clinical essay on RE+ bc chemotherapy and Uncaria tomentosa, Cat’s claw, with positive results on neutrophils. I used Ut 3gr three times a day with boiling water and after 2 weeks they rose to 2.8 and another 2 weeks later they were at 3.6. Commented it with my onco and she confirmed there's no interference with ribociclib. Unfortunately I had to stop treatment with ribociclib because of bad liver values. I don’t know if it is safe to use in combination con Trodelvy, you should ask your onc.

All my best wishes to you and a hug from … (northern) Spain!

[Tanyateresa in reply to Pimpelmees]

Hi there, thanksvery much for that. My oncologist is not that keen on supplements precisely because of the effect on liver. I am on one capsule of Reishi 6500 mg but it hasn't made much difference to my white blood cell count. So I will look into the cats claw. Thanks!! Good to hear from another Spanish resident!! All the best!!

[Best521]

My start with Trodelvy was tough. Low white blood cell counts, gastrointestinal issues etc., however once the dosage was lowered the white blood cell counts came back. Occasionally I have low red blood cell counts. My oncologist wants to keep the load off my liver and protect it. Unless it is medically necessary I do not take any supplements, over the counter drugs or prescription drugs. I want my liver to last a long time.

[Tanyateresa in reply to Best521]

Hi good to hear from another Trodelvy gal. Well yes my oncologist is also not keen on supplements because of the liver issue. Maybe they will have to lower the dosage a bit....

How long have too been on Trodelvy?

[Best521]

I have been on Trodelvy for 1 year. The scans show my tumors shrank 25%. My tumor markers continue to drop a bit each cycle . The infusion nurse told me she has a patient who has been on Trodelvy for 2 years. I am grateful to be able to have this life extending treatment and fingers crossed it keeps working.