I've been on Ibrance and Letrozole since MBC diagnosis in August 2019 to bones and marrow (after primary bilateral mastectomy, immediate lat dorsi reconstruction, chemo, rads, and Herceptin in 2010). Stable CT scans since, but now AST liver enzyme rising, my Ferritin (which is odd with low haemoglobin) and AST is very high, my haemoglobin has started to drop since Christmas after being stable at just normal range of 115g/L, WBC always low from Ibrance so I am on 75mg and a 2 week break. LDH has gone through the roof to 2483 (normal top of the range is 214!). All my other liver function tests are normal apart from AST but I am having a full liver report done. Told it is probably Ibrance or baddies growing in the marrow.... so feeling so very anxious and worried what treatment is possible next. I have read that if you have bone metastases then it is often in the marrow too, but doesn't always affect the blood.
Thank you so much for any input!
Best wishes to you all,