Not the results we wanted from my first pet scan last week since my diagnosis of MBC in September. After only three months on Ibrance, all of the spots had decreased in size or remained stable EXCEPT for the liver. There were 2 new small spots on the liver, and my oncologist said we had to change medications to try a new route. Now I am on Afinitor and Aromasin. I was doing so good on Ibrance, I really hated to start a whole new drug path after only 3 months. Has anyone had a similar situation?