Firstly, thanks for all the support and information over the past few weeks, there is a core of really dedicated people to this forum, and we all owe than a big thank you.
An update as brief as I can make it on my situation.
I have a good GP, but have also consulted a French GP at the Holistic Clinic to get his advice and lots of tests to check all bases, which proved interesting. I had no skin allergies and no food intolerance issues, which was good. The issues he did pick up, several, generally appear to be just outside the normal range but he said they all contribute to the inflammation problem I have, and that I am not controlling and processing fat well enough which is a compounding problem. They include the following- INSULIN 23.5mU/L (double normal 5 – 13). - HOMOCYSTEINE 17.4 umol/L (5 – 15 max). - THYROID FUNCTION T3, T4 OK but TSH 4.1mlU/L (0.3 – 4.0). - SERUM CORTISOL 700nmol/L (200 – 700nmol/L) - SERUM B12 300pmol/L said it needs to be 400. And a CANDIDA PATTERN a food yeast issue that is not right in my diet. We have avoided sugar where possible for ages.
For the above situation, he has prescribed daily – Red Yeast Rice 600mg tablets, building up to 4 tablets daily over 6 days, plus 2/150mg CoQ10 tablets. 1/200mg Selenium tablet for 3 weeks. A 1000mcg B12 injection once a week for 3 weeks. In addition to what the doctor has prescribed, I take 250mg of Magnesium Malate, 125mg of Calcium, an Aspirin and Apple Cider Vinegar in the mornings. I have completely changed my diet and would be now 90% organic and about 85% vegan, plus giving up the one glass of wine a night and going alcohol free. I need to lose about 7kg to reach my optimum weight.
I try to swim 400m most days plus do a light work out in the gym, once or twice a week, plus walking.
What is really interesting is my ESR result on 17 March was 16 mm/hr (0 – 25) so normal. My CRP result on 16 March was 6mg/L and on the 29 March was 10 mg/L , both of which I would consider low, based on comments I have read on this blog but my doctor calls 10mg/L high as it is above 5!
Both doctors advised me to take Prednisone, which you are aware I was trying hard to avoid, but after weighing up all the advice, reluctantly started on 15mg, which I take as one dose at lunch time. My first dose was on 1 April; within 2 hours I had a 30% improvement, 5 hours 60 – 70% improvement, which continued until I virtually reached 100% no aches and pains within say 10 hours. Had one of the best night’s sleep in a while, but about 4am I started to get slight aches in the upper arm muscles, about 20% of what it was. The fact I have had such a positive response, by what I have read, seems to confirm I do have PMR although the ESR and CRP results don’t seem that dramatic.
I return to my GP tomorrow, to bring her up to speed on the past 3 weeks, and plan my Pred over the next few months. Obviously, I would like to get down to at least 7.5mg as soon as possible, but do not want to make the mistake of tapering too quickly, so therefore would appreciate your advice on the following. What is the best time to take Pred, I’m taking it at lunchtime? Is it better to do one dose, which is easier, or spread it out over the day? I’m starting on 15mg, can I drop to 10mg quickly – what is your advice here? Bearing in mind all the information I have provided, what do you think is a sensible taping programme, timeframes & dose, for me to help avoid the obvious setbacks that do happen.
My son suggested I buy a Shakti Mat $69NZ, made in India- google shaktimat.co.nz I’m sure there is a uk site – looks interesting, you may find it beneficial and wish to look it up.
Hope I have not over done it again! But it all adds to the knowledge bank. Kind Regards John