I have been suffering from rectal & pelvic floor pain for last 18 months. 2 months ago I was placed on Prucalopride as the magnesium citrate they I was taking stopped working. My pelvic floor pain & rectal spasm appears to be getting worse. I used to be able to sleep at night but now struggling. Has anyone else noticed this? Are they connected? Do I need to adjust anything whilst taking Prucalopride?
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Hopetobewell
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Hi, yes I do have constipation which is why I am on Prucalopride. No mention made of impact on spasms but have noticed that since I started taking it the pelvic floor spasms have got worse. Wondered if there was a connection
I got terribly unwell on prucalopride - twice they made me try it for slow transit. Both times severe headache with flu-like symptoms and numb swollen face and lips 24/7. I’ve finally got it acknowledged as an adverse reaction. I take picolax syrup , Linaclotide and domperidone (Gastroparesis) and use Peristeen plus once daily. It’s a huge burden but no side effects apart from fecal incontinence so have to plan accordingly. I’ve begged for illeostomy but so far surgeon feels risks too high for me.
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