Hi. I'm new to here. I've had depression on and off since I was 18 and always been on medication. I'm 47 now and this particular bout of depression has been going on for over 2 years and is terrible. I've been seeing a CPN and psychiatrist. In April this year I had Electro convulsive therapy and shortly after had to go into hospital for a couple of weeks because I felt so awful. I've got a loving wife, two lovely children and no money worries so no external reasons to be depressed. The meds I'm taking are Lithium, Vortioxetine, Quetiapine, Pregabalin and they've just started me on Liothyronine last week. I've not been able to work for 20 months. I feel so desperately depressed, I don't socialise anymore and often isolate myself in the bedroom. I can't see an end to this misery.