Plaquenil and Calcium/Vit D: For those of you who... - LUPUS UK

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Plaquenil and Calcium/Vit D

Purpletop profile image
11 Replies

For those of you who take calcium tablets, I saw on drugs.com (there is a facility to check drug interactions)that taking Plaquenil at the same time with calcium could reduce the efficacy of Plaquenil by up to 50%. To get around that, it is best to leave 4 hours between taking either of them. The doctor's indication on my Plaquenil packet does say not to take antacids for 2 hours within taking Plaquenil but I didn't realise that calcium tablets have a similar effect.

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Purpletop profile image
Purpletop
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11 Replies

thats useful info,thanks

Sher78 profile image
Sher78

I find the whole 'Calcium' thing confusing, I have too much calcium in my body which can in turn affect Raynauds but my bones, nails, teeth r so weak, it's hilarious, they break at the slightest thing (& no, I'm not just talking about my nails either!), this is part of the reason I will not touch steroids

Purpletop profile image
Purpletop in reply toSher78

Oh my God, I didn't realise one can have too much Calcium! I'm taking 1000mg a day to be on the safe side, what with menopause and steroids etc.

Tigerlily4 profile image
Tigerlily4 in reply toPurpletop

It seems 3,000mg per day is the correct dose of Calcium/Vit D when taking steroids Purple so I woudn't worry too much.

Purpletop profile image
Purpletop in reply toTigerlily4

Brilliant, thank you for letting me know. Sher raised a good point in that some people might be predisposed to calcium accumulation, I just never thought of it. My blood tests last week were fine where calcium was concerned, so I will continue at my normal dose and stagger it away from Plaquenil at 4 hour difference.

Tigerlily4 profile image
Tigerlily4 in reply toPurpletop

Welcome :)

Sher78 profile image
Sher78

I don't think it's a problem 4 every1 but considering too much calcium can make u're blood clot quicker (which aint exactly helpful if u have Antiphospholipid lol!), cause extreme fatigue, kidney & liver problems, muscle weakness, low blood pressure, circulation problems, erratic brain function, cns problems (sounds a lot like lupus eh?!) etc if u ALREADY have problems with this, obviously it's ADDING 2 it & sending everything in2 hyper drive. There r certain signs they look 4 so don't panic too much but maybe an idea 2 get levels checked every now & again. Normal range is between 2.1 mmol per litre and 2.6 mmol per litre of blood. If u notice u start 2 get calcium 'spots' (kind of like whiteheads) on u're chest, shoulders, arms etc when u don't actually suffer from spots then ask 2 have u're levels checked ;0)

Purpletop profile image
Purpletop in reply toSher78

This is when I feel like I'm in the twilight zone, few months ago I thought I'm just tired and in need of a proper holiday, today I'm looking into white spots on arms, how life can change so dramatically so quickly!

Thank you, Sher, helpful as ever.

Sher78 profile image
Sher78

Hopefully they're nothing as I haven't met many lupoids who have constantly have crazy Calcium levels. I've pulled up a couple of links 4 u. Just 2 clarify, my level is ALWAYS too high & although they have tried 2 reduce my calcium production, nothing works 4 me, (my grandad had arterial calcification so there may be some link there 4 me but then again maybe just coincidence) but just 2 reiterate, many meds can (such as the contraceptive pill, some diuretics, diethylstilbesterol (DES), antacids, etc) also increase our calcium levels plus if u actually sat down & looked at how much calcium we actually consume (& it's NOT just in dairy people, many things have 'added calcium now such as bread & a few fruit & veggies contain it too) we would probably find we r taking in enough. But DON'T PANIC, my aim is just 2 make people aware as the docs sometimes 2 4get 2 tell us about certain things. npr.org/blogs/health/20... aakp.org/aakp-library/t...

Sue2803 profile image
Sue2803

I take Calcichew and Plaquenil, but take Calcichew in mornings and Plaquenil after dinner in the evenings.

Sher78 profile image
Sher78

I don't take any Cal supplement or vit D & I don't go mad or any cal enriched foods/drinks or dairy so it's a bit of a mystery & I certainly don't take any meds 2 push my levels up. I guess some of us r just awkward buggers ;0)

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