Methotrexate

[LouLamb]

Hi.

I'm currently back on methotrexate tablets have been since end of Jan. I've gotten up to 7.5mg. The goal was 10mg. My liver result went up few weeks ago so was told to take tablets another 2 weeks and check again. It's gone back down to normal now. I've been told if it goes back up again when I get my blood test next week I will need to try something else.

I'm just wondering what other meds people have tried if methotrexate didn't work for them and how long it took. I'm currently taking hydroxy as well. I've only tried leflunomide in the past but that raised my liver result and was stopped.

I'm still currently on steroids which will end the beginning of July. I'm worried if I have to change meds there will be a period of delay in ending steroids and the new meds working. I wish steroids were a long term fix I've felt great since being on them since January.

I hope everyone is doing well. I'm on countdown to half term now which is great 😀

[mickey_in_cincy]

I have lupus and was put on prednisone which seemed to help. When i was put on hydroxychloroquine and methotrexate i got blood clots in my legs, vertigo, and severe eye strain. Please be safe.

[LouLamb in reply to mickey_in_cincy]

I’m currently on prednisone. Which has been great but obviously not a long term fix.

[TJB59]

Hi loulambI've been on methotrexate on for about 10 months ,my last bloods show that my liver is having a tough time but at the moment i take 17.5ml every Friday ,I was talking to my consultant about my blood test results my problem is i also take pregabalin this also messed with my liver my doctor wants me to go for a liver ultrasound scan and if it shows that my liver is not coping he tells me he will be putting me on injections on the injections it's apparently a lot easier because you don't have to have blood test every month you have a blood test every 3 to 4 months so if I was you I'd ask about going on the injections apparently it's a lot easier and it doesn't cause liver problems the injections are also delivered to your house for you ,sounds better than being on methotrexate, before my nurse specialist leave she said to me the best thing is injections ,but before you go on the injections you have to jump through a few hoops like showing an intolerance to methotrexate, because the injections cost a lot of money and tablets are very cheap compared to the injections plus depending on which injections they put you on some you take every month and some you take every two months,if it was me I would go on the injections if I was offered them, because the methotrexate is causing me problems the next step for me is injections and I can't wait to be honest ,hope this helps a bit .

And good luck 😀👍.

[LouLamb in reply to TJB59]

I use to have injections. I’ve tried them twice in the past. They just are not for me. I mentally couldn’t do it. I would be worrying every day about having to do it. It made me feel sick all the worrying. That’s why I agreed to do tablets again.

[TJB59 in reply to LouLamb]

Oh I see how that case your better off on the tablets but if you don't get on with the tablets ,it doesn't,leave you a lot of choice does it ,it wouldn't bother me injections ,but if you don't like doing it that's understandable some people don't like injections ,when I have injections into watch them doing it I'm not that bothered,I'm not saying he like them but if it's going to be better for me than the tablets ,I can do the injections it's doesn't bother me really