I’m not sure if anyone can offer an insight to the information I have.
Routine blood test for my lupus sle and the liver count was 100 rather than being the usual 25. I’ve been advised to not take methotrexate this week and the rheumatology nurse advised that it means my my liver is having to work much harder as indicated by this reading.
I’ve had another blood test today and awaiting results but just confused as to what the raised blood count is actually showing.
Does anyone have any idea?
Mint thanks
Written by
Sin123
To view profiles and participate in discussions please or .
Hi.it could be showing inflammation of the liver.i had to stop taking azathioprine as I developed drug induced hepatitis.i then had to wait 3 months for my liver to recover before starting mycophenolate instead. It does resolve itself once the drug is stopped Xxx
Oh, ok. Thanks for reply. I’ve been on mthx for 2 1/2 years with no issue to date so that’s interesting. My hair is also shedding so wonder if they’re related?...
Sorry I cant help on that score.by asking you not to take the drug and re testing your bloods they could possibly be looking to see if the methotrexate is the cause.best wishes xx
Patients may drink alcohol whilst taking long-term low weekly doses of methotrexate (25mg or less) for skin conditions, rheumatoid arthritis and other inflammatory conditions, but they should be advised that both alcohol and methotrexate can potentially damage the liver, so they should not drink more alcohol than ...22 Sep 2020
Did you result go back to normal? I have been taken off my mycophenolate as Alt high had second bloods still high and only had liver scan 4 weeks ago which was all fine. Consultant wants me to see liver specialist.
Hi.it took 3 months for my liver to recover after the azathioprine caused the drug induced hepatitis. I'm still on monthly dmards bloods and all is ok.after 5 months they put me on mycophenolate. I've now been on that for 18 months xx
Sorry you are having a worrying time. It may be that your liver is working extra hard and maybe you need a break from the MTX. Link in with the Rheumatology nurse she can support you. I have thinning hair too, however I think that it is part of the connective tissue disorder rather than the medication, and I have had Methotrexate, Mycophenolate and now Rituximab but I use shampoo with caffeine in, which helps a bit.
Hi hope your feeling better. I am on Methotrexate and when I first started she started me at 8 pills once a week, shortly after that my blood work showed that my liver count was up so she lowered Me to 6. After a few months my liver count went back to normal. However my RA was not as good as it could have been so she raised me up to seven. So far so good. Hope this was helpful
My liver count has now come down to 80 from 100 so my rheumatologist wants me to take another test in two weeks and to also take an antibody test. She’s advised I stay off mthx in the meantime. I currently don’t have any symptoms so really hoping the count will continue to come down.
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
Blood test results? Book recommendation? 
Blood test results
Test result guidance
Generic Blood Test Results to start initial tests for Lupus show raised liver enzymes.
Low vitamin d levels and low full blood count- and more tablets
